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Peter A. Jones
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Journal Articles

Abstract CT121: A Phase II trial of guadecitabine (G) plus atezolizumab (A) in patients with metastatic urothelial carcinoma (UC) progressing after initial checkpoint inhibitor therapy

Elizabeth R. Plimack, Kerry Campbell, Jean-Pierre J. Issa, Noah M. Hahn, David I. Quinn, Hyo Sik Jang, Galen Hostetter, Peter W. Nichols, Woonbok Chung, Jozef Madzo, Hitoshi Ohtani, Hui Shen, Toshinori Hinoue, Stephen B. Baylin, Peter A. Jones
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT121.
https://doi.org/10.1158/1538-7445.AM2021-CT121
Published: 01 July 2021
View article titled, Abstract CT121: A Phase II trial of guadecitabine (G) plus atezolizumab (A) in patients with metastatic urothelial carcinoma (UC) progressing after initial checkpoint inhibitor therapy
Journal Articles

George F. Vande Woude: In Memoriam (1935–2021)

Peter A. Jones
Journal: Cancer Research
Cancer Res (2021) 81 (11): 2805–2806.
https://doi.org/10.1158/0008-5472.CAN-21-1345
Published: 01 June 2021
View article titled, George F. Vande Woude: In Memoriam (1935–2021)
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Journal Articles

Abstract IA14: Increasing viral mimicry with vitamin C

Peter A. Jones
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): IA14.
https://doi.org/10.1158/1538-7445.EPIMETAB20-IA14
Published: 02 December 2020
View article titled, Abstract IA14: Increasing viral mimicry with vitamin C
Journal Articles

Abstract 1078: The nucleosomal acidic patch helps anchor of de novo DNA methyltransferase DNMT3A2/3B3 complex

Ting-Hai Xu, Minmin Liu, Edward Zhou, Gangning Liang, Eric H. Xu, Karsten Melcher, Peter A. Jones
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1078.
https://doi.org/10.1158/1538-7445.AM2020-1078
Published: 15 August 2020
View article titled, Abstract 1078: The nucleosomal acidic patch helps anchor of <em>de novo</em> DNA methyltransferase DNMT3A2/3B3 complex
Journal Articles

Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine

Hitoshi Ohtani, Andreas D. Ørskov, Alexandra S. Helbo, Linn Gillberg, Minmin Liu, Wanding Zhou, Johanna Ungerstedt, Eva Hellström-Lindberg, Weili Sun, Gangning Liang, Peter A. Jones, Kirsten Grønbæk
Journal: Cancer Research
Cancer Res (2020) 80 (12): 2441–2450.
https://doi.org/10.1158/0008-5472.CAN-19-1696
Published: 15 June 2020
View article titled, Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine
Open the PDF for Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine in another window
Includes: Supplementary data
Journal Articles

Abstract 3092: Activation of evolutionarily young transposable elements and the host innate immune system are linked to clinical response to 5-azacitidine

Hitoshi Ohtani, Andreas D. Ørskov, Alexandra S. Helbo, Linn Gillberg, Minmin Liu, Wanding Zhou, Johanna Ungerstedt, Eva Hellstrom-Lindberg, Weili Sun, Gangning Liang, Peter A. Jones, Kirsten Grønbæk
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3092.
https://doi.org/10.1158/1538-7445.AM2019-3092
Published: 01 July 2019
View article titled, Abstract 3092: Activation of evolutionarily young transposable elements and the host innate immune system are linked to clinical response to 5-azacitidine
Journal Articles

Dual Inhibition of DNA and Histone Methyltransferases Increases Viral Mimicry in Ovarian Cancer Cells

Minmin Liu, Stacey L. Thomas, Ashley K. DeWitt, Wanding Zhou, Zachary B. Madaj, Hitoshi Ohtani, Stephen B. Baylin, Gangning Liang, Peter A. Jones
Journal: Cancer Research
Cancer Res (2018) 78 (20): 5754–5766.
https://doi.org/10.1158/0008-5472.CAN-17-3953
Published: 15 October 2018
View article titled, Dual Inhibition of DNA and Histone Methyltransferases Increases Viral Mimicry in Ovarian Cancer Cells
Open the PDF for Dual Inhibition of DNA and Histone Methyltransferases Increases Viral Mimicry in Ovarian Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 2993: A switch in epigenetic silencing mechanisms of endogenous retroviruses during human genome evolution

Hitoshi Ohtani, Minmin Liu, Wanding Zhou, Gangning Liang, Peter A. Jones
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2993.
https://doi.org/10.1158/1538-7445.AM2018-2993
Published: 01 July 2018
View article titled, Abstract 2993: A switch in epigenetic silencing mechanisms of endogenous retroviruses during human genome evolution
Journal Articles

Abstract IA14: Targeting human endogenous retroviruses for epigenetic therapy

Peter A. Jones
Journal: Cancer Research
Cancer Res (2017) 77 (22_Supplement): IA14.
https://doi.org/10.1158/1538-7445.NEWFRONT17-IA14
Published: 14 November 2017
View article titled, Abstract IA14: Targeting human endogenous retroviruses for epigenetic therapy
Journal Articles

Identification of DNA Methylation–Independent Epigenetic Events Underlying Clear Cell Renal Cell Carcinoma

Elinne Becket, Sameer Chopra, Christopher E. Duymich, Justin J. Lin, Jueng Soo You, Kurinji Pandiyan, Peter W. Nichols, Kimberly D. Siegmund, Jessica Charlet, Daniel J. Weisenberger, Peter A. Jones, Gangning Liang
Journal: Cancer Research
Cancer Res (2016) 76 (7): 1954–1964.
https://doi.org/10.1158/0008-5472.CAN-15-2622
Published: 31 March 2016
View article titled, Identification of DNA Methylation–Independent Epigenetic Events Underlying Clear Cell Renal Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Abstract IA04: How DNA methylation organizes the cancer epigenome

Peter A. Jones
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): IA04.
https://doi.org/10.1158/1538-7445.CHROMEPI15-IA04
Published: 14 January 2016
View article titled, Abstract IA04: How DNA methylation organizes the cancer epigenome
Journal Articles

Abstract B03: Identification of epigenetic regulated genes through simultaneous analysis of DNA methylation and chromatin structure in uncultured tumors

Elinne Becket, Sameer Chopra, Christopher Duymich, Lin J. Justin, Jueng Soo You, Kurinji Pandiyan, Peter W. Nichols, Kimberly D. Siegmund, Peter A. Jones, Gangning Liang
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): B03.
https://doi.org/10.1158/1538-7445.CHROMEPI15-B03
Published: 14 January 2016
View article titled, Abstract B03: Identification of epigenetic regulated genes through simultaneous analysis of DNA methylation and chromatin structure in uncultured tumors
Journal Articles

Abstract B02: The role of chromatin remodeler protein ARID1a in ovarian clear cell carcinoma

Ranjani Lakshminarasimhan, Claudia Andreu-Vieyra, Kate Lawrenson, Simon A. Gayther, Peter A. Jones, Gangning Liang
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): B02.
https://doi.org/10.1158/1538-7445.CHROMEPI15-B02
Published: 14 January 2016
View article titled, Abstract B02: The role of chromatin remodeler protein ARID1a in ovarian clear cell carcinoma
Journal Articles

Abstract IA20: DNA methylation and nucleosome repositioning in cancer

Peter A. Jones
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): IA20.
https://doi.org/10.1158/1538-7445.FBCR11-IA20
Published: 28 October 2014
View article titled, Abstract IA20: DNA methylation and nucleosome repositioning in cancer
Journal Articles

Abstract LB-130: Simultaneous evaluation of chromatin accessibility and DNA methylation in clear cell renal cell carcinoma by a newly developed assay, AcceSssIble

Elinne Becket, Christopher Duymich, Yin-Wei Chang, Kurinji Pandiyan, Peter A. Jones, Gangning Liang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-130.
https://doi.org/10.1158/1538-7445.AM2014-LB-130
Published: 01 October 2014
View article titled, Abstract LB-130: Simultaneous evaluation of chromatin accessibility and DNA methylation in clear cell renal cell carcinoma by a newly developed assay, AcceSssIble
Journal Articles

Abstract 4780: The effects of the global loss of DNA methylation on the functional organization of the epigenome

Fides D. Lay, Yaping Liu, Theresa K. Kelly, Heather Witt, Adam Blattler, Peggy J. Farnham, Ben P. Berman, Peter A. Jones
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4780.
https://doi.org/10.1158/1538-7445.AM2014-4780
Published: 01 October 2014
View article titled, Abstract 4780: The effects of the global loss of DNA methylation on the functional organization of the epigenome
Journal Articles

Abstract PR07: SNF5 is an essential executor of epigenetic regulation during differentiation

Jueng Soo You, Daniel D. De Carvalho, Chao Dai, Minmin Liu, Kurinji Pandiyan, Xianghong Zhou, Gangning Liang, Peter A. Jones
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): PR07.
https://doi.org/10.1158/1538-7445.CEC13-PR07
Published: 13 May 2014
View article titled, Abstract PR07: SNF5 is an essential executor of epigenetic regulation during differentiation
Journal Articles

Abstract IA16: Reactivating epigenetically silenced genes

Peter A. Jones
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): IA16.
https://doi.org/10.1158/1538-7445.CEC13-IA16
Published: 13 May 2014
View article titled, Abstract IA16: Reactivating epigenetically silenced genes
Journal Articles

Abstract B56: DNA demethylation in gene bodies is of therapeutic significance

Han Han Zhang, Xiaojing Yang, Daniel D. De Carvalho, Peter A. Jones, Gangning Liang
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): B56.
https://doi.org/10.1158/1538-7445.CEC13-B56
Published: 13 May 2014
View article titled, Abstract B56: DNA demethylation in gene bodies is of therapeutic significance
Journal Articles

Abstract A11: Role of chromatin remodeler mutations in urothelial cell carcinoma of the bladder

Christopher E. Duymich, Jessica Charlet, Gangning Liang, Peter A. Jones
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): A11.
https://doi.org/10.1158/1538-7445.CEC13-A11
Published: 13 May 2014
View article titled, Abstract A11: Role of chromatin remodeler mutations in urothelial cell carcinoma of the bladder