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Journal Articles

Abstract PO5-24-06: Genomic findings in metastatic breast cancer

Kimberly Cole, Melissa Tjota, Jeremy Segal, Peng Wang, Susanne Crespo-Ramos
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-24-06.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-24-06
Published: 02 May 2024
View article titled, Abstract PO5-24-06: Genomic findings in metastatic breast cancer
Journal Articles

Abstract 6560: Cell-free RNA analysis for non-invasive cancer detection and characterization

Monica C. Nesselbush, Bogdan A. Luca, Young-Jun Jeon, Isabel Jabara, Catherine B. Meador, Michael S. Binkley, Nova Xu, Angela B. Hui, Andrea Garofalo, William Y. Shi, Kevin J. Liu, Takeshi Sugio, Noah Kastelowitz, Emily G. Hamilton, Rene F. Bonilla, Yi Peng Wang, Alice Jiang, Brianna Lau, Jordan Eichholz, Mandeep Banwait, Joseph Schroers-Martin, Jan Boegeholz, Daniel A. King, Mohammad S. Esfahani, Tyler Raclin, Robert Tibshirani, Sandy Srinivas, Viswam S. Nair, James M. Isbell, Bob T. Li, Zofia Piotrowska, Lecia V. Sequist, Aaron N. Hata, Joel W. Neal, Heather A. Wakelee, Andrew J. Gentles, Ash A. Alizadeh, Maximilian Diehn
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6560.
https://doi.org/10.1158/1538-7445.AM2024-6560
Published: 22 March 2024
View article titled, Abstract 6560: Cell-free RNA analysis for non-invasive cancer detection and characterization
Journal Articles

Abstract 5940: JAB-30355: A highly potent, orally bioavailable p53-Y220C reactivator

Qian Zheng, Peng Wang, Chen Liang, Yao Li, Xin Sun, Amin Li, Wei Zhang, Wei Long, Yanping Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5940.
https://doi.org/10.1158/1538-7445.AM2024-5940
Published: 22 March 2024
View article titled, Abstract 5940: JAB-30355: A highly potent, orally bioavailable p53-Y220C reactivator
Journal Articles

Abstract 1660: Preclinical investigation of orally bioavailable, potent KRASMulti inhibitor JAB-23425

Peng Wang, Yanping Wang, Xin Sun, Dan Liu, Xiaoyu Liu, Wei Zhang, Xueting He, Rui Zhou, Cunbo Ma, Amin Li, Yiwei Lin, Wei Long
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1660.
https://doi.org/10.1158/1538-7445.AM2023-1660
Published: 04 April 2023
View article titled, Abstract 1660: Preclinical investigation of orally bioavailable, potent KRAS<sup>Multi</sup> inhibitor JAB-23425
Journal Articles

Abstract 241: Evaluation of single cell RNA sequencing from FFPE tissue using 10x Genomics Chromium Fixed RNA Profiling

Adam J. Black, Emily Wiseman, Peng Wang, Douglas Wilson, Fernando Torres, Joseph Modarelli
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 241.
https://doi.org/10.1158/1538-7445.AM2023-241
Published: 04 April 2023
View article titled, Abstract 241: Evaluation of single cell RNA sequencing from FFPE tissue using 10x Genomics Chromium Fixed RNA Profiling
Journal Articles

Abstract A015: Targeting necroptosis and RIP3 in colorectal cancer to overcome chemotherapeutic resistance

Kaylee A. Ermine, Dongshi Chen, Peng Wang, Jian Yu, Lin Zhang
Journal: Cancer Research
Cancer Res (2022) 82 (23_Supplement_1): A015.
https://doi.org/10.1158/1538-7445.CRC22-A015
Published: 01 December 2022
View article titled, Abstract A015: Targeting necroptosis and RIP3 in colorectal cancer to overcome chemotherapeutic resistance
Journal Articles

MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma

Tian Gan, Yan Wang, Manyi Xie, Qiang Wang, Saisai Zhao, Peng Wang, Qinyu Shi, Xuanchen Qian, Faan Miao, Zhigang Shen, Er Nie
Journal: Cancer Research
Cancer Res (2022) 82 (22): 4234–4246.
https://doi.org/10.1158/0008-5472.CAN-22-2036
Published: 15 November 2022
View article titled, MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma
Open the PDF for MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 3461: Focused ultrasound induced blood-tumor barrier permeability of combinatorial chemotherapy

Tasneem A. Arsiwala, Kathryn E. Blethen, Samuel A. Sprowls, Ross A. Fladeland, Brooke Keilkowski, Morgan Glass, Trenton Pritt, Peng Wang, Ali Rezai, Paul R. Lockman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3461.
https://doi.org/10.1158/1538-7445.AM2022-3461
Published: 15 June 2022
View article titled, Abstract 3461: Focused ultrasound induced blood-tumor barrier permeability of combinatorial chemotherapy
Journal Articles

Abstract 358: Restoring necroptosis in colorectal cancer cells to overcome chemotherapeutic resistance

Kaylee Ermine, Dongshi Chen, Peng Wang, Jian Yu, Lin Zhang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 358.
https://doi.org/10.1158/1538-7445.AM2022-358
Published: 15 June 2022
View article titled, Abstract 358: Restoring necroptosis in colorectal cancer cells to overcome chemotherapeutic resistance
Journal Articles

CDK4/6 Inhibition Suppresses p73 Phosphorylation and Activates DR5 to Potentiate Chemotherapy and Immune Checkpoint Blockade

Jingshan Tong, Xiao Tan, Xiangping Song, Man Gao, Denise Risnik, Suisui Hao, Kaylee Ermine, Peng Wang, Hua Li, Yi Huang, Jian Yu, Lin Zhang
Journal: Cancer Research
Cancer Res (2022) 82 (7): 1340–1352.
https://doi.org/10.1158/0008-5472.CAN-21-3062
Published: 01 April 2022
View article titled, CDK4/6 Inhibition Suppresses p73 Phosphorylation and Activates DR5 to Potentiate Chemotherapy and Immune Checkpoint Blockade
Open the PDF for CDK4/6 Inhibition Suppresses p73 Phosphorylation and Activates DR5 to Potentiate Chemotherapy and Immune Checkpoint Blockade in another window
Includes: Supplementary data
Journal Articles

Correction: The EZH2-PHACTR2-AS1- Ribosome Axis Induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer

Wenhui Chu, Xi Zhang, Lihua Qi, Yenan Fu, Peng Wang, Wei Zhao, Juan Du, Jing Zhang, Jun Zhan, Yunling Wang, Wei-Guo Zhu, Yu Yu, Hongquan Zhang
Journal: Cancer Research
Cancer Res (2022) 82 (4): 735.
https://doi.org/10.1158/0008-5472.CAN-21-4346
Published: 15 February 2022
View article titled, Correction: The EZH2-PHACTR2-AS1- Ribosome Axis Induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer
Open the PDF for Correction: The EZH2-PHACTR2-AS1- Ribosome Axis Induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer in another window
Journal Articles

A Notch-Dependent Inflammatory Feedback Circuit between Macrophages and Cancer Cells Regulates Pancreatic Cancer Metastasis

Yawen Geng, Jie Fan, Lianyu Chen, Chenyue Zhang, Chao Qu, Ling Qian, Kun Chen, Zhiqiang Meng, Zhen Chen, Peng Wang
Journal: Cancer Research
Cancer Res (2021) 81 (1): 64–76.
https://doi.org/10.1158/0008-5472.CAN-20-0256
Published: 04 January 2021
View article titled, A Notch-Dependent Inflammatory Feedback Circuit between Macrophages and Cancer Cells Regulates Pancreatic Cancer Metastasis
Open the PDF for A Notch-Dependent Inflammatory Feedback Circuit between Macrophages and Cancer Cells Regulates Pancreatic Cancer Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 3916: Patient-derived organoid and cell culture models from the NCI Patient-Derived Models Repository (NCI PDMR) preserve genomic stability and heterogeneity of patient tumor specimens

Biswajit Das, Yvonne A. Evrard, Li Chen, Rajesh Patidar, Tomas Vilimas, Justine N. McCutcheon, Amanda L. Peach, Nikitha V. Nair, Thomas D. Forbes, Brandie A. Fullmer, Anna J. Lee Fong, Luis E. Romero, Alyssa K. Chapman, Kelsey A. Conley, Robin D. Harrington, Shahanawaz S. Jiwani, Peng Wang, Michelle M. Gottholm-Ahalt, Erin N. Cantu, Gloryvee Rivera, Lindsay M. Dutko, Kelly M. Benauer, Vishnuprabha R. Kannan, Carrie A. Bonomi, Kelly M. Dougherty, Joseph P. Geraghty, Marion V. Gibson, Savanna S. Styers, Abigail J. Walke, Jenna E. Moyer, Anna Wade, Mariah L. Baldwin, Kaitlyn A. Arthur, Kevin J. Plater, Luke Stockwin, Matthew R. Murphy, Michael E. Mullendore, Dianne L. Newton, Melinda G. Hollingshead, Chris A. Karlovich, Paul M. Williams, James H. Doroshow
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3916.
https://doi.org/10.1158/1538-7445.AM2020-3916
Published: 15 August 2020
View article titled, Abstract 3916: Patient-derived organoid and cell culture models from the NCI Patient-Derived Models Repository (NCI PDMR) preserve genomic stability and heterogeneity of patient tumor specimens
Journal Articles

Abstract 5056: Quality control efforts in a large-scale, preclinical trial of rare cancer PDXs by the National Cancer Institute's patient-derived models repository (NCI PDMR)

Yvonne A. Evrard, Biswajit Das, Sergio Y. Alcoser, Suzanne Borgel, Devynn Breen, John Carter, Tiffanie Chase, Alice Chen, Lily Chen, Kristen Cooley, Emily Delaney, Raymond Divelbiss, Lyndsay Dutko, Thomas Forbes, Kyle Georgius, Michelle Gottholm-Ahalt, Tara Grinnage-Pulley, Sierra Hoffman, Chris Karlovich, Shahanawaz Jiwani, Justine Mills, Malorie Morris, Michael Mullendore, Dianne Newton, Rajesh Patidar, Gloryvee Rivera, Howard Stotler, Jesse Stottlemyer, Savanna Styers, Debbie Trail, Shannon Uzelac, Thomas Vilimas, Abigail Walke, Thomas Walsh, Nicole Walters, Peng Wang, P. Mickey Williams, Melinda Hollingshead, James H. Doroshow
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5056.
https://doi.org/10.1158/1538-7445.AM2020-5056
Published: 15 August 2020
View article titled, Abstract 5056: Quality control efforts in a large-scale, preclinical trial of rare cancer PDXs by the National Cancer Institute's patient-derived models repository (NCI PDMR)
Journal Articles

Abstract 3554: Genomic landscape of acquired uniparental disomy in NCI PDMR patient derived xenograft models

Rajesh Patidar, Li Chen, Chris A. Karlovich, Biswajit Das, Yvonne A. Evrard, Tomas Vilimas, Justine N. McCutcheon, Amanda L. Peach, Nikitha V. Nair, Thomas D. Forbes, Brandie A. Fullmer, Anna J. Lee Fong, Luis E. Romero, Alyssa K. Chapman, Kelsey A. Conley, Robin D. Harrington, Shahanawaz S. Jiwani, Peng Wang, Michelle M. Gottholm Ahalt, Erin N. Cantu, Gloryvee Rivera, Lindsay M. Dutko, Kelly M. Benauer, Vishnuprabha R. Kannan, Suzanne D. Borgel, John P. Carter, Jesse M. Stottlemyer, Tiffanie L. Miner, Devynn R. Breen, Emily T. Delaney, Chelsea A. McGlynn, Candace N. Mallow, Marianne Radzyminski, Shannon N. Uzelac, Sergio Y. Alcoser, Tara L. Grinnage-Pulley, Michelle A. Eugeni, Dianne L. Newton, Melinda G. Hollingshead, Paul M. Williams, James H. Doroshow
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3554.
https://doi.org/10.1158/1538-7445.AM2020-3554
Published: 15 August 2020
View article titled, Abstract 3554: Genomic landscape of acquired uniparental disomy in NCI PDMR patient derived xenograft models
Journal Articles

Abstract 35: Construction of ce-RNA networks and comprehensive analysis with tumor infiltrating immune cells in hepatocellular carcinoma

Jianxiang Shi, Chi Cui, Yaru Duan, Hua Ye, Peng Wang, Jitian Li, Shuiling Jin, Liping Dai, Jianying Zhang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 35.
https://doi.org/10.1158/1538-7445.AM2020-35
Published: 15 August 2020
View article titled, Abstract 35: Construction of ce-RNA networks and comprehensive analysis with tumor infiltrating immune cells in hepatocellular carcinoma
Journal Articles

The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer

Wenhui Chu, Xi Zhang, Lihua Qi, Yenan Fu, Peng Wang, Wei Zhao, Juan Du, Jing Zhang, Jun Zhan, Yunling Wang, Wei-Guo Zhu, Yu Yu, Hongquan Zhang
Journal: Cancer Research
Cancer Res (2020) 80 (13): 2737–2750.
https://doi.org/10.1158/0008-5472.CAN-19-3326
Published: 02 July 2020
View article titled, The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer
Open the PDF for The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract P4-09-01: Clinical sequencing characterizes the genomic landscape and actionable mutations of Chinese breast cancer

Guan-Tian Lang, Jin-Xiu Shi, Yi-Zhou Jiang, Xiao-Guang Li, Yu-Chen Pei, Fang-Lin Zhang, Chen-Hui Zhang, Ding Ma, Yi Xiao, Ke-Da Yu, Peng-Chen Hu, Ming-Liang Jin, Hai Wang, Yun-Song Yang, Xuan Luo, Qi Hong, Feng Qiao, Wei-Li Sun, Meng-Zhu Xue, Shi-Ping Li, A-Yong Cao, Zhong-Hua Wang, Jia-Xin Zhang, Gen-Hong Di, Peng Wang, Da-Qiang Li, Xin Hu, Wei Huang, Zhi-Ming Shao
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-09-01.
https://doi.org/10.1158/1538-7445.SABCS19-P4-09-01
Published: 15 February 2020
View article titled, Abstract P4-09-01: Clinical sequencing characterizes the genomic landscape and actionable mutations of Chinese breast cancer
Journal Articles

Abstract P4-05-02: Machine learning predicts rapid relapse in triple negative breast cancer

Yiqing Zhang, William Nock, Meghan Wyse, Zachary Weber, Elizabeth J Adams, Asad Sarah, Sinclair Stockard, David Tallman, Jasneet Singh, Junu Bae, Eric P Winer, Nancy U Lin, Yi-Zhou Jiang, Ding Ma, Peng Wang, Leming Shi, Wei Huang, Zhi-Ming Shao, Claire Verschraegen, Mathew Cherian, Maryam B Lustberg, Bhuvana Ramaswamy, Sagar Sardesai, Jeffrey VanDeusen, Nicole Williams, Wesolowski Robert, Daniel G Stover
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-05-02.
https://doi.org/10.1158/1538-7445.SABCS19-P4-05-02
Published: 15 February 2020
View article titled, Abstract P4-05-02: Machine learning predicts rapid relapse in triple negative breast cancer
Journal Articles

A Feedback Circuitry between Polycomb Signaling and Fructose-1, 6-Bisphosphatase Enables Hepatic and Renal Tumorigenesis

Kun Liao, Shuye Deng, Liyan Xu, Wenfeng Pan, Shiyu Yang, Fufu Zheng, Xingui Wu, Hongrong Hu, Zhijun Liu, Junhang Luo, Rui Zhang, Dong-Ming Kuang, Jiajun Dong, Yi Wu, Hui Zhang, Penghui Zhou, Jin-Xin Bei, Yang Xu, Yin Ji, Peng Wang, Huai-Qiang Ju, Rui-Hua Xu, Bo Li
Journal: Cancer Research
Cancer Res (2020) 80 (4): 675–688.
https://doi.org/10.1158/0008-5472.CAN-19-2060
Published: 14 February 2020
View article titled, A Feedback Circuitry between Polycomb Signaling and Fructose-1, 6-Bisphosphatase Enables Hepatic and Renal Tumorigenesis
Open the PDF for A Feedback Circuitry between Polycomb Signaling and Fructose-1, 6-Bisphosphatase Enables Hepatic and Renal Tumorigenesis in another window
Includes: Supplementary data