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Abstract 3826: A therapeutically actionable pro-tumoral axis of cytokines involving interleukin-8, TNFα and IL-1β

Irene Olivera, Rebeca Sanz-Pamplona, Elixabet Bolaños, Inmaculada Rodriguez, Iñaki Etxeberria, Assunta Cirella, Saray Garasa, Itziar Migueliz, Iñaki Eguren, Miguel F. Sanmamed, Javier Glez-Vaz, Arantza Azpilikueta, Maite Alvarez, Maria C. Ochoa, Carlos E. De Andrea, Pedro Berraondo, Álvaro Teijeira, Ignacio Melero

Cancer Res (2022) 82 (12_Supplement): 3826.

DOI: https://doi.org/10.1158/1538-7445.AM2022-3826

Published: 15 June 2022

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Journal Articles

Abstract 1691: CD137 (4-1BB) costimulation of CD8 T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation

Itziar Otano, Arantza Azpilikueta, Javier Glez-Vaz, Peter Ellmark, Sara Fritzell, Gabriela Fernandez-Hoyos, Michelle Hase Nelson, Maite Alvarez, María del Carmen Ochoa, Elixabet Bolaños, Doina Cuculescu, Patricia Jauregui, Sandra Sanchez, Iñaki Etxeberría, María E. Rodriguez-Ruiz, Miguel F. Sanmamed, Alvaro Teijeira, Pedro Berraondo, Igancio Melero

Cancer Res (2021) 81 (13_Supplement): 1691.

DOI: https://doi.org/10.1158/1538-7445.AM2021-1691

Published: 01 July 2021

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Journal Articles

Abstract 1698: Cellular cytotoxicity is a form of immunogenic cell death

Luna Minute, Alvaro Teijeira, Alfonso Rodriguez Sánchez-Paulete, Maria del Carmen Ochoa, Maite Alvarez, Itziar Otano, Iñaki Etxeberria, Elixabet Bolaños, Arantza Azpilikueta, Saray Garasa, Noelia Casares, José Luiz Pérez-Gracia, Maria Esperanza Rodríguez-Ruiz, Pedro Berraondo, Ignacio Melero

Cancer Res (2020) 80 (16_Supplement): 1698.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1698

Published: 15 August 2020

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Journal Articles

Abstract 2331: Intratumor adoptive transfer of IL-12 mRNA transiently engineered anti-tumor CD8+ T cells

Inaki Etxeberria, Elixabet Bolaños, Alvaro Teijeira, Arantza Azpilicueta, Jose Ignacio Quetglas, Alfonso Rodriguez Sanchez-Paulete, Itziar Otano, Uxua Mancheño, Sandra Hervas-Stubbs, Susana Inoges, Saray Garasa, Maite Alvarez, Pedro Berraondo, Ignacio Melero

Cancer Res (2019) 79 (13_Supplement): 2331.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2331

Published: 01 July 2019

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Journal Articles

Abstract 1474: Repurposing the yellow fever vaccine for intratumoral immunotherapy

M. Angela Aznar, Carmen Molina, Alvaro Teijeira, Arantza Azpilikueta, Saray Garasa, Alfonso R. Sanchez-Paulete, Iñaki Etxeberria, Maite Alvarez, Pedro Berraondo, Ignacio Melero

Cancer Res (2019) 79 (13_Supplement): 1474.

DOI: https://doi.org/10.1158/1538-7445.AM2019-1474

Published: 01 July 2019

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Journal Articles

Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus–Derived Vectors Fosters Dendritic Cell–Mediated T-cell Cross-Priming

Alfonso R. Sánchez-Paulete, Álvaro Teijeira, José I. Quetglas, María E. Rodríguez-Ruiz, Álvaro Sánchez-Arráez, Sara Labiano, Iñaki Etxeberria, Arantza Azpilikueta, Elixabet Bolaños, María Cristina Ballesteros-Briones, Noelia Casares, Sergio A. Quezada, Pedro Berraondo, David Sancho, Cristian Smerdou, Ignacio Melero

Cancer Res (2018) 78 (23): 6643–6654.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-0933

Published: 03 December 2018

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Includes: Supplementary data

Journal Articles

Abstract LB-151: Prophylactic TNFα blockade unplugs toxicity and efficacy in immunotherapy anti-PD-1 + anti-CTLA-4 combinations

ELISABETH PEREZ-RUIZ, LUNA MINUTE, MARIA CARMEN OCHOA, ARANTXA AZPILICUETA, SARAY GARASA, M E RODRIGUEZ-RUIZ, VIRGINIA BELSUE, CARMEN MOLINA, PEDRO BERRAONDO, IGNACIO MELERO

Cancer Res (2018) 78 (13_Supplement): LB-151.

DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-151

Published: 01 July 2018

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Journal Articles

Immunostimulatory Monoclonal Antibodies and Immunomodulation: Harvesting the Crop

Pedro Berraondo, María Carmen Ochoa, María Esperanza Rodriguez-Ruiz, Luna Minute, Juan José Lasarte, Ignacio Melero

Cancer Res (2016) 76 (10): 2863–2867.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-3279

Published: 12 May 2016

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Includes: Supplementary data

Journal Articles

Abstract 1223: Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein.

Maria Carmen Ochoa, Pedro Berraondo, Ignacio Melero

Cancer Res (2013) 73 (8_Supplement): 1223.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1223

Published: 15 April 2013

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Journal Articles

Antitumor Immunotherapeutic and Toxic Properties of an HDL-Conjugated Chimeric IL-15 Fusion Protein

Maria C. Ochoa, Jessica Fioravanti, Inmaculada Rodriguez, Sandra Hervas-Stubbs, Arantza Azpilikueta, Guillermo Mazzolini, Alfonso Gúrpide, Jesus Prieto, Julian Pardo, Pedro Berraondo, Ignacio Melero

Cancer Res (2013) 73 (1): 139–149.

DOI: https://doi.org/10.1158/0008-5472.CAN-12-2660

Published: 02 January 2013

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Includes: Supplementary data

Journal Articles

Changing the Tumor Microenvironment: New Strategies for Immunotherapy

Pedro Berraondo, Viktor Umansky, Ignacio Melero

Cancer Res (2012) 72 (20): 5159–5164.

DOI: https://doi.org/10.1158/0008-5472.CAN-12-1952

Published: 14 October 2012

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Includes: Supplementary data

Journal Articles

Eradication of Large Tumors in Mice by a Tritherapy Targeting the Innate, Adaptive, and Regulatory Components of the Immune System

Pedro Berraondo, Clémence Nouzé, Xavier Préville, Daniel Ladant, Claude Leclerc

Cancer Res (2007) 67 (18): 8847–8855.

DOI: https://doi.org/10.1158/0008-5472.CAN-07-0321

Published: 17 September 2007

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Includes: Supplementary data

Journal Articles

Low Surface Expression of B7-1 (CD80) Is an Immunoescape Mechanism of Colon Carcinoma

Iñigo Tirapu, Eduardo Huarte, Cristiana Guiducci, Ainhoa Arina, Mikel Zaratiegui, Oihana Murillo, Alvaro Gonzalez, Carmen Berasain, Pedro Berraondo, Puri Fortes, Jesús Prieto, Mario P. Colombo, Lieping Chen, Ignacio Melero

Cancer Res (2006) 66 (4): 2442–2450.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-1681

Published: 17 February 2006

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Includes: Supplementary data

NARROW

Abstract 3826: A therapeutically actionable pro-tumoral axis of cytokines involving interleukin-8, TNFα and IL-1β

Abstract 1691: CD137 (4-1BB) costimulation of CD8 T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation

Abstract 1698: Cellular cytotoxicity is a form of immunogenic cell death

Abstract 2331: Intratumor adoptive transfer of IL-12 mRNA transiently engineered anti-tumor CD8+ T cells

Abstract 1474: Repurposing the yellow fever vaccine for intratumoral immunotherapy

Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus–Derived Vectors Fosters Dendritic Cell–Mediated T-cell Cross-Priming

Abstract LB-151: Prophylactic TNFα blockade unplugs toxicity and efficacy in immunotherapy anti-PD-1 + anti-CTLA-4 combinations

Immunostimulatory Monoclonal Antibodies and Immunomodulation: Harvesting the Crop

Abstract 1223: Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein.

Antitumor Immunotherapeutic and Toxic Properties of an HDL-Conjugated Chimeric IL-15 Fusion Protein

Changing the Tumor Microenvironment: New Strategies for Immunotherapy

Eradication of Large Tumors in Mice by a Tritherapy Targeting the Innate, Adaptive, and Regulatory Components of the Immune System

Low Surface Expression of B7-1 (CD80) Is an Immunoescape Mechanism of Colon Carcinoma

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