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Pearl S. Huang
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Journal Articles

Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Nelson Rhodes, Dirk A. Heerding, Derek R. Duckett, Derek J. Eberwein, Victoria B. Knick, Timothy J. Lansing, Randy T. McConnell, Tona M. Gilmer, Shu-Yun Zhang, Kimberly Robell, Jason A. Kahana, Robert S. Geske, Elena V. Kleymenova, Anthony E. Choudhry, Zhihong Lai, Jack D. Leber, Elisabeth A. Minthorn, Susan L. Strum, Edgar R. Wood, Pearl S. Huang, Robert A. Copeland, Rakesh Kumar
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2366–2374.
https://doi.org/10.1158/0008-5472.CAN-07-5783
Published: 01 April 2008
View article titled, Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
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Includes: Supplementary data
Journal Articles

Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic BRAF by the Kinase Inhibitor SB-590885

Alastair J. King, Denis R. Patrick, Roberta S. Batorsky, Maureen L. Ho, Hieu T. Do, Shu Yun Zhang, Rakesh Kumar, David W. Rusnak, Andrew K. Takle, David M. Wilson, Erin Hugger, Lifu Wang, Florian Karreth, Julie C. Lougheed, Jae Lee, David Chau, Thomas J. Stout, Earl W. May, Cynthia M. Rominger, Michael D. Schaber, Lusong Luo, Ami S. Lakdawala, Jerry L. Adams, Rooja G. Contractor, Keiran S.M. Smalley, Meenhard Herlyn, Michael M. Morrissey, David A. Tuveson, Pearl S. Huang
Journal: Cancer Research
Cancer Res (2006) 66 (23): 11100–11105.
https://doi.org/10.1158/0008-5472.CAN-06-2554
Published: 04 December 2006
View article titled, Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <em>BRAF</em> by the Kinase Inhibitor SB-590885
Open the PDF for Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <em>BRAF</em> by the Kinase Inhibitor SB-590885 in another window
Includes: Supplementary data
Journal Articles

In vitro and in vivo biology of a small molecular weight Tpo receptor agonist, SB-497115

Connie L. Erickson-Miller, Juan I. Luengo, Richard Nicholl, Daphne Williams, Charlotte Baidoo, Jennifer Phillips, Yanli Deng, Evelyne Delorme, Leslie Giampa, Christopher B. Hopson, Elizabeth I. Valoret, Pearl S. Huang, Shin-Shay Tian, Stephen G. Miller, Richard M. Keenan, Jon Rosen, Susan B. Dillon, Kevin Duffy, Valerie Kitchen, Peter Lamb, Julian M. Jenkins
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 603.
Published: 01 May 2005
View article titled, In vitro and in vivo biology of a small molecular weight Tpo receptor agonist, SB-497115
Journal Articles

A novel, potent and selective small molecule inhibitor of B-Raf kinase, SB-590885, inhibits signal transduction and growth of cells bearing the B-Raf V600E mutation

Alastair J. King, Denis R. Patrick, Roberta S. Batorsky, Maureen L. Ho, Hieu T. Do, David W. Rusnak, Andrew K. Takle, David M. Wilson, Lifu Wang, Florian Karreth, Michael D. Schaber, John J. Voycik, Lusong Luo, Ami S. Lakdawala, Jerry L. Adams, Keiran S. M. Smalley, Meenhard Herlyn, David A. Tuveson, Pearl S. Huang
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1250.
Published: 01 May 2005
View article titled, A novel, potent and selective small molecule inhibitor of B-Raf kinase, SB-590885, inhibits signal transduction and growth of cells bearing the B-Raf V600E mutation