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Pawel Kalinski
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Journal Articles

Abstract A047 Synergy between polarized dendritic cells, radiation and PD-1 blockade in effective treatment of rhabdomyosarcoma

Free
Ajay Gupta, Eoghan Connors, Michael Moser, Bryan Gillard, Katie Kokolus, Per Basse, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): A047.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-A047
Published: 05 September 2024
View articletitled, Abstract A047 Synergy between polarized dendritic cells, radiation and PD-1 blockade in effective treatment of rhabdomyosarcoma
Journal Articles

Abstract PO1-18-03: Chemokine-modulating regimen (rintatolimod, IFN-α2b, celecoxib): New strategy to drive CD8+T-cells into triple negative breast cancer

Free
Shipra Gandhi, Cayla Jones, Mateusz Opyrchal, Ronald Slomba, Kristopher Attwood, Jianmin Wang, Eduardo Cortes Gomez, Tracey O'Connor, Ellis Levine, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-18-03.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-18-03
Published: 02 May 2024
View articletitled, Abstract PO1-18-03: Chemokine-modulating regimen (rintatolimod, IFN-α2b, celecoxib): New strategy to drive CD8+T-cells into triple negative breast cancer
Journal Articles

Abstract PO4-25-03: Comprehensive immune profiling reveals factors associated with neoadjuvant chemotherapy response in triple negative breast cancer

Free
Robert Seager, Heidi Ko, Sarabjot Pabla, Maria-Fernanda Senosain, Pawel Kalinski, Erik Van Roey, Shuang Gao, Kyle Strickland, Rebecca Previs, Mary Nesline, Stephanie Hastings, Shengle Zhang, Jeffrey Conroy, Taylor Jensen, Marcia Eisenberg, Brian Caveney, Eric Severson, Shakti Ramkissoon, Shipra Gandhi
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-25-03.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-25-03
Published: 02 May 2024
View articletitled, Abstract PO4-25-03: Comprehensive immune profiling reveals factors associated with neoadjuvant chemotherapy response in triple negative breast cancer
Journal Articles

Abstract 6744: Activating anti-MDS immunity with polarized dendritic cell vaccines

Free
Daniel Alvarado, Jennifer Peresie, Adam Brinkman, Cheryl Allen, Weijian Jiang, Pawel Kalinski, Tiffany Tanaka, Elizabeth Griffiths, Michael Nemeth
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6744.
https://doi.org/10.1158/1538-7445.AM2024-6744
Published: 22 March 2024
View articletitled, Abstract 6744: Activating anti-MDS immunity with polarized dendritic cell vaccines
Journal Articles

Abstract 3966: NK receptors enable TCR-mediated CTL recognition and killing of cancer cells expressing non-mutated tumor-associated antigens

Free
Bowen Dong, Nataša Obermajer, Takemasa Tsuji, Junko Matsuzaki, Cindy Bonura, Henry Withers, Mark Long, Colin Chavel, Scott H. Olejniczak, Hans Minderman, Robert P. Edwards, Walter J. Storkus, Pedro Romero, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3966.
https://doi.org/10.1158/1538-7445.AM2024-3966
Published: 22 March 2024
View articletitled, Abstract 3966: NK receptors enable TCR-mediated CTL recognition and killing of cancer cells expressing non-mutated tumor-associated antigens
Journal Articles

Abstract P4-06-07: Preliminary indications of safety and efficacy of neoadjuvant chemotherapy plus chemokine-modulating regimen (rintatolimod, IFN-α2b, celecoxib) in triple negative breast cancer

Free
Shipra Gandhi, Mateusz Opyrchal, Cayla Ford, Ronald Slomba, Kristopher Attwood, Tracey O’Connor, Ellis Levine, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-06-07.
https://doi.org/10.1158/1538-7445.SABCS22-P4-06-07
Published: 01 March 2023
View articletitled, Abstract P4-06-07: Preliminary indications of safety and efficacy of neoadjuvant chemotherapy plus chemokine-modulating regimen (rintatolimod, IFN-α2b, celecoxib) in triple negative breast cancer
Journal Articles

Abstract 3127: Negative impact of paclitaxel on human breast tumor microenvironment and its reversal by the combination of interferon-α with TLR3 agonist rintatolimod

Free
Shipra Gandhi, Melissa Grimm, Ronald Slomba, Kazuaki Takabe, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3127.
https://doi.org/10.1158/1538-7445.AM2022-3127
Published: 15 June 2022
View articletitled, Abstract 3127: Negative impact of paclitaxel on human breast tumor microenvironment and its reversal by the combination of interferon-α with TLR3 agonist rintatolimod
Journal Articles

Abstract CT145: Systemic rintatolimod and interferon-α2b selectively reprogram local tumor microenvironment in patients with metastatic triple negative breast cancer for enhanced influx of cytotoxic T-lymphocytes but not regulatory T-cells

Free
Shipra Gandhi, Mateusz Opyrchal, Melissa Grimm, Ronald Slomba, Kathleen Kokolus, Sebastiano Battaglia, Kristopher Attwood, Adrienne Groman, Lauren Williams, Mary Lynne Tarquini, Paul Wallace, Kah Teong Soh, Tracey O'Connor, Amy Early, Ellis Levine, Igor Puzanov, Marc Ernstoff, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT145.
https://doi.org/10.1158/1538-7445.AM2022-CT145
Published: 15 June 2022
View articletitled, Abstract CT145: Systemic rintatolimod and interferon-α2b selectively reprogram local tumor microenvironment in patients with metastatic triple negative breast cancer for enhanced influx of cytotoxic T-lymphocytes but not regulatory T-cells
Journal Articles

Abstract CT105: Initial results of a phase II study evaluating a chemokine-modulatory (CKM) regimen in patients with colorectal cancer metastatic to the liver

Free
Sarbajit Mukherjee, Patrick M. Boland, Melissa Grimm, Ronald Slomba, Kristopher Attwood, Renuka Iyer, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT105.
https://doi.org/10.1158/1538-7445.AM2022-CT105
Published: 15 June 2022
View articletitled, Abstract CT105: Initial results of a phase II study evaluating a chemokine-modulatory (CKM) regimen in patients with colorectal cancer metastatic to the liver
Journal Articles

Abstract PS6-49: Intratumoral cytotoxic t-lymphocyte numbers and chemokine predict long-term survival of triple-negative breast cancer independently of tumor mutational burden

Free
Eriko Katsuta, Li Yan, Mateusz Opyrchal, Pawel Kalinski, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS6-49.
https://doi.org/10.1158/1538-7445.SABCS20-PS6-49
Published: 15 February 2021
View articletitled, Abstract PS6-49: Intratumoral cytotoxic t-lymphocyte numbers and chemokine predict long-term survival of triple-negative breast cancer independently of tumor mutational burden
Journal Articles

Abstract 6616: Functional hotness score generated by representative functional cytotoxic T-lymphocytes predicts long-term survival of triple-negative breast cancer independently to the tumor mutational burden

Free
Eriko Katsuta, Li Yan, Mateusz Opyrchal, Pawel Kalinski, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6616.
https://doi.org/10.1158/1538-7445.AM2020-6616
Published: 15 August 2020
View articletitled, Abstract 6616: Functional hotness score generated by representative functional cytotoxic T-lymphocytes predicts long-term survival of triple-negative breast cancer independently to the tumor mutational burden
Journal Articles

Abstract 968: Distinct pathways of DC-induced CD8+T cell differentiation revealed by single-cell mRNA sequencing analysis

Free
Bowen Dong, Sarabjot Pabla, Vincent Giamo, Weijian Jiang, Kiyomi Taniguchi, Sean T. Glenn, Masataka Shirai, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 968.
https://doi.org/10.1158/1538-7445.AM2020-968
Published: 15 August 2020
View articletitled, Abstract 968: Distinct pathways of DC-induced CD8+T cell differentiation revealed by single-cell mRNA sequencing analysis
Journal Articles

Abstract 970: Single-cell mRNA sequencing analysis of the synergistic impact of double-stranded RNA (dsRNA) and IFNα on human monocyte-derived macrophages

Free
Vincent Giamo, Melissa Grimm, Sarabjot Pabla, Ellen Karasik, Jesse Luce, Sean T. Glenn, Jeffrey Conroy, Jeffrey Conroy, Barbara Foster, Kiyomi Taniguchi, Pawel Kalinski, Masataka Shirai
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 970.
https://doi.org/10.1158/1538-7445.AM2020-970
Published: 15 August 2020
View articletitled, Abstract 970: Single-cell mRNA sequencing analysis of the synergistic impact of double-stranded RNA (dsRNA) and IFNα on human monocyte-derived macrophages
Journal Articles

Abstract P3-07-07: Functional hotness score of cytotoxic T-lymphocytes infiltration to predicts outcome of triple-negative breast cancer patients

Free
Eriko Katsuta, Li Yan, Mateusz Opyrchal, Pawel Kalinski, Kazuaki Takabe
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-07-07.
https://doi.org/10.1158/1538-7445.SABCS19-P3-07-07
Published: 15 February 2020
View articletitled, Abstract P3-07-07: Functional hotness score of cytotoxic T-lymphocytes infiltration to predicts outcome of triple-negative breast cancer patients
Journal Articles

Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment

Free
Marie-Nicole Theodoraki, Saigopalakrishna Yerneni, Saumendra N. Sarkar, Brian Orr, Ravikumar Muthuswamy, Jamie Voyten, Francesmary Modugno, Weijian Jiang, Melissa Grimm, Per H. Basse, David L. Bartlett, Robert P. Edwards, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2018) 78 (15): 4292–4302.
https://doi.org/10.1158/0008-5472.CAN-17-3985
Published: 31 July 2018
View articletitled, Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment
Open the PDF for Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment in another window
Includes: Supplementary data
Journal Articles

Abstract 951: Induction of COX-2 and NFκB activation represent TLR3-independent undesirable aspects of poly-I:C activity

Free
Marie-Nicole Theodoraki, Ravi Muthuswamy, Jamie Voyten, Francesmary Modugno, Natasa Obermajer, Robert P. Edwards, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 951.
https://doi.org/10.1158/1538-7445.AM2017-951
Published: 01 July 2017
View articletitled, Abstract 951: Induction of COX-2 and NFκB activation represent TLR3-independent undesirable aspects of poly-I:C activity
Journal Articles

Abstract B44: Enabling in vivo visualization of cellular therapies in the clinic: Maturation of αDC1 data sets.

Free
Brooke M. Helfer, Anthony Balducci, Julie Urban, Lisa Butterfield, Eric Ahrens, Pawel Kalinski, Amy Wesa
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): B44.
https://doi.org/10.1158/1538-7445.TUMIMM2012-B44
Published: 02 April 2014
View articletitled, Abstract B44: Enabling in vivo visualization of cellular therapies in the clinic: Maturation of αDC1 data sets.
Journal Articles

IL-18–Primed Helper NK Cells Collaborate with Dendritic Cells to Promote Recruitment of Effector CD8+ T Cells to the Tumor Microenvironment

Free
Jeffrey L. Wong, Erik Berk, Robert P. Edwards, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2013) 73 (15): 4653–4662.
https://doi.org/10.1158/0008-5472.CAN-12-4366
Published: 31 July 2013
View articletitled, IL-18–Primed Helper NK Cells Collaborate with Dendritic Cells to Promote Recruitment of Effector CD8+ T Cells to the Tumor Microenvironment
Open the PDF for IL-18–Primed Helper NK Cells Collaborate with Dendritic Cells to Promote Recruitment of Effector CD8+ T Cells to the Tumor Microenvironment in another window
Includes: Supplementary data
Journal Articles

NF-κB Hyperactivation in Tumor Tissues Allows Tumor-Selective Reprogramming of the Chemokine Microenvironment to Enhance the Recruitment of Cytolytic T Effector Cells

Free
Ravikumar Muthuswamy, Erik Berk, Beth Fallert Junecko, Herbert J. Zeh, Amer H. Zureikat, Daniel Normolle, The Minh Luong, Todd A. Reinhart, David L. Bartlett, Pawel Kalinski
Journal: Cancer Research
Cancer Res (2012) 72 (15): 3735–3743.
https://doi.org/10.1158/0008-5472.CAN-11-4136
Published: 31 July 2012
View articletitled, NF-κB Hyperactivation in Tumor Tissues Allows Tumor-Selective Reprogramming of the Chemokine Microenvironment to Enhance the Recruitment of Cytolytic T Effector Cells
Open the PDF for NF-κB Hyperactivation in Tumor Tissues Allows Tumor-Selective Reprogramming of the Chemokine Microenvironment to Enhance the Recruitment of Cytolytic T Effector Cells in another window
Includes: Supplementary data
Journal Articles

Defective NF-κB Signaling in Metastatic Head and Neck Cancer Cells Leads to Enhanced Apoptosis by Double-Stranded RNA

Free
Naoki Umemura, Jianzhong Zhu, Yvonne K. Mburu, Adriana Forero, Paishiun N. Hsieh, Ravikumar Muthuswamy, Pawel Kalinski, Robert L. Ferris, Saumendra N. Sarkar
Journal: Cancer Research
Cancer Res (2012) 72 (1): 45–55.
https://doi.org/10.1158/0008-5472.CAN-11-1484
Published: 02 January 2012
View articletitled, Defective NF-κB Signaling in Metastatic Head and Neck Cancer Cells Leads to Enhanced Apoptosis by Double-Stranded RNA
Open the PDF for Defective NF-κB Signaling in Metastatic Head and Neck Cancer Cells Leads to Enhanced Apoptosis by Double-Stranded RNA in another window
Includes: Supplementary data