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Paula M. Vertino
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Journal Articles

Abstract C019: The circadian master regulator BMAL1 blocks immune cell recognition of pancreatic ductal adenocarcinomas by reducing proteasome activity and MHC1 cell surface localization

Orjola Prela, Lan Wang, Ching-Hua Shih, Juliana Cazarin de Menezes, Brian Altman, Paula M. Vertino, Chris R. Harris, Darren R. Carpizo
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): C019.
https://doi.org/10.1158/1538-7445.PANCA2023-C019
Published: 16 January 2024
View article titled, Abstract C019: The circadian master regulator BMAL1 blocks immune cell recognition of pancreatic ductal adenocarcinomas by reducing proteasome activity and MHC1 cell surface localization
Journal Articles

Abstract 525: Targeting interleukin-1 receptor-associated kinase 1/4 in acute myeloid leukemia stem cells

Tzu-Chieh Ho, Rakesh K. Singh, Hiroki Kawano, Mark W. LaMere, Jian Wang, Paula M. Vertino, Nikolay V. Dokholyan, Laura M. Calvi, Craig T. Jordan, Michael W. Becker
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 525.
https://doi.org/10.1158/1538-7445.AM2023-525
Published: 04 April 2023
View article titled, Abstract 525: Targeting interleukin-1 receptor-associated kinase 1/4 in acute myeloid leukemia stem cells
Journal Articles

Abstract 3597: SUV420H2-mediated regulation of collective invasion in triple-negative breast cancer

Emily Campbell Whitt, Laura M. McLane, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3597.
https://doi.org/10.1158/1538-7445.AM2023-3597
Published: 04 April 2023
View article titled, Abstract 3597: SUV420H2-mediated regulation of collective invasion in triple-negative breast cancer
Journal Articles

Combined Inhibition of G9a and EZH2 Suppresses Tumor Growth via Synergistic Induction of IL24-Mediated Apoptosis

Francesco Casciello, Gregory M. Kelly, Priya Ramarao-Milne, Nabilah Kamal, Teneale A. Stewart, Pamela Mukhopadhyay, Stephen H. Kazakoff, Mariska Miranda, Dorim Kim, Felicity M. Davis, Nicholas K. Hayward, Paula M. Vertino, Nicola Waddell, Frank Gannon, Jason S. Lee
Journal: Cancer Research
Cancer Res (2022) 82 (7): 1208–1221.
https://doi.org/10.1158/0008-5472.CAN-21-2218
Published: 01 April 2022
View article titled, Combined Inhibition of G9a and EZH2 Suppresses Tumor Growth via Synergistic Induction of IL24-Mediated Apoptosis
Open the PDF for Combined Inhibition of G9a and EZH2 Suppresses Tumor Growth via Synergistic Induction of IL24-Mediated Apoptosis in another window
Includes: Supplementary data
Journal Articles

Abstract 839: Whole genome DNA methylation analysis of multiple myeloma identifies pervasive hypomethylation and biomarkers of survival

Benjamin G. Barwick, Doris R. Powell, Daniel Penaherrera, Sheri Skerget, Jonathan J. Keats, Daniel Auclair, Sagar Lonial, Lawrence H. Boise, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 839.
https://doi.org/10.1158/1538-7445.AM2019-839
Published: 01 July 2019
View article titled, Abstract 839: Whole genome DNA methylation analysis of multiple myeloma identifies pervasive hypomethylation and biomarkers of survival
Journal Articles

Abstract 4590: Dissecting the biology of leader and follower cells in collective cancer invasion

Brian A. Pedro, Jessica Konen, Emily Summerbell, Janna K. Mouw, Manali Rupji, Bhakti Dwivedi, Jeanne Kowalski, Paula M. Vertino, Adam I. Marcus
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4590.
https://doi.org/10.1158/1538-7445.AM2019-4590
Published: 01 July 2019
View article titled, Abstract 4590: Dissecting the biology of leader and follower cells in collective cancer invasion
Journal Articles

Abstract PR08: GC skew defines distinct RNA polymerase pause sites in CpG island promoters

Joshua SK Bell, Wendy A. Kellner, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): PR08.
https://doi.org/10.1158/1538-7445.CHROMEPI15-PR08
Published: 14 January 2016
View article titled, Abstract PR08: GC skew defines distinct RNA polymerase pause sites in CpG island promoters
Journal Articles

Abstract 2105: Regulation of estrogen receptor turnover by lysine 302 methylation

Elizabeth L. Zoeller, Dalia Barsyte-Lovejoy, Peter J. Brown, Dafydd R. Owen, Cheryl H. Arrowsmith, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2105.
https://doi.org/10.1158/1538-7445.AM2014-2105
Published: 01 October 2014
View article titled, Abstract 2105: Regulation of estrogen receptor turnover by lysine 302 methylation
Journal Articles

Abstract A57: Dual role of the histone methyltransferase PR-SET7/SETD8 in the local regulation of Pol II promoter-proximal pausing

Priya Kapoor, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): A57.
https://doi.org/10.1158/1538-7445.CEC13-A57
Published: 13 May 2014
View article titled, Abstract A57: Dual role of the histone methyltransferase PR-SET7/SETD8 in the local regulation of Pol II promoter-proximal pausing
Journal Articles

Overexpression of MBD2 in Glioblastoma Maintains Epigenetic Silencing and Inhibits the Antiangiogenic Function of the Tumor Suppressor Gene BAI1

Dan Zhu, Stephen B. Hunter, Paula M. Vertino, Erwin G. Van Meir
Journal: Cancer Research
Cancer Res (2011) 71 (17): 5859–5870.
https://doi.org/10.1158/0008-5472.CAN-11-1157
Published: 30 August 2011
View article titled, Overexpression of MBD2 in Glioblastoma Maintains Epigenetic Silencing and Inhibits the Antiangiogenic Function of the Tumor Suppressor Gene <em>BAI1</em>
Open the PDF for Overexpression of MBD2 in Glioblastoma Maintains Epigenetic Silencing and Inhibits the Antiangiogenic Function of the Tumor Suppressor Gene <em>BAI1</em> in another window
Includes: Supplementary data
Journal Articles

Abstract 822: Withaferin A inhibits breast cancer invasion and metastasis at subcytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

Jose T. Thaiparambil, Laura Bender, Thota Ganesh, Erik Kline, Pritty Patel, Yuan Liu, Mourad Tighiouart, Paula M. Vertino, R Donald Harvey, Anapatricia Garcia, Adam Marcus
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 822.
https://doi.org/10.1158/1538-7445.AM2011-822
Published: 15 April 2011
View article titled, Abstract 822: Withaferin A inhibits breast cancer invasion and metastasis at subcytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
Journal Articles

Silencing of TMS1/ASC Promotes Resistance to Anoikis in Breast Epithelial Cells

Melissa J. Parsons, Pritty Patel, Daniel J. Brat, Laronna Colbert, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2009) 69 (5): 1706–1711.
https://doi.org/10.1158/0008-5472.CAN-08-2351
Published: 02 March 2009
View article titled, Silencing of TMS1/ASC Promotes Resistance to Anoikis in Breast Epithelial Cells
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Journal Articles

A Multifactorial Signature of DNA Sequence and Polycomb Binding Predicts Aberrant CpG Island Methylation

Michael T. McCabe, Eva K. Lee, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2009) 69 (1): 282–291.
https://doi.org/10.1158/0008-5472.CAN-08-3274
Published: 31 December 2008
View article titled, A Multifactorial Signature of DNA Sequence and Polycomb Binding Predicts Aberrant CpG Island Methylation
Open the PDF for A Multifactorial Signature of DNA Sequence and Polycomb Binding Predicts Aberrant CpG Island Methylation in another window
Includes: Supplementary data
Journal Articles

LKB1 Is Necessary for Akt-Mediated Phosphorylation of Proapoptotic Proteins

Diansheng Zhong, Xiuju Liu, Fadlo R. Khuri, Shi-Yong Sun, Paula M. Vertino, Wei Zhou
Journal: Cancer Research
Cancer Res (2008) 68 (18): 7270–7277.
https://doi.org/10.1158/0008-5472.CAN-08-1484
Published: 14 September 2008
View article titled, LKB1 Is Necessary for Akt-Mediated Phosphorylation of Proapoptotic Proteins
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Includes: Supplementary data
Journal Articles

Role of hMOF-Dependent Histone H4 Lysine 16 Acetylation in the Maintenance of TMS1/ASC Gene Activity

Priya Kapoor-Vazirani, Jacob D. Kagey, Doris R. Powell, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2008) 68 (16): 6810–6821.
https://doi.org/10.1158/0008-5472.CAN-08-0141
Published: 12 August 2008
View article titled, Role of hMOF-Dependent Histone H4 Lysine 16 Acetylation in the Maintenance of <em>TMS1/ASC</em> Gene Activity
Open the PDF for Role of hMOF-Dependent Histone H4 Lysine 16 Acetylation in the Maintenance of <em>TMS1/ASC</em> Gene Activity in another window
Journal Articles

The Tumor Suppressor LKB1 Regulates Lung Cancer Cell Polarity by Mediating cdc42 Recruitment and Activity

Shumin Zhang, Katherine Schafer-Hales, Fadlo R. Khuri, Wei Zhou, Paula M. Vertino, Adam I. Marcus
Journal: Cancer Research
Cancer Res (2008) 68 (3): 740–748.
https://doi.org/10.1158/0008-5472.CAN-07-2989
Published: 01 February 2008
View article titled, The Tumor Suppressor LKB1 Regulates Lung Cancer Cell Polarity by Mediating cdc42 Recruitment and Activity
Open the PDF for The Tumor Suppressor LKB1 Regulates Lung Cancer Cell Polarity by Mediating cdc42 Recruitment and Activity in another window
Includes: Supplementary data
Journal Articles

FOXO3a phosphorylation at threonine32 requires both Akt and LKB1 in NSCLC cell lines

Diansheng Zhong, Xiuju Liu, Shi-Yong Sun, Paula M. Vertino, Wei Zhou
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 280.
Published: 01 May 2007
View article titled, FOXO3a phosphorylation at threonine32 requires both Akt and LKB1 in NSCLC cell lines
Journal Articles

Restoration of Tamoxifen Sensitivity in Estrogen Receptor–Negative Breast Cancer Cells: Tamoxifen-Bound Reactivated ER Recruits Distinctive Corepressor Complexes

Dipali Sharma, Neeraj K. Saxena, Nancy E. Davidson, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2006) 66 (12): 6370–6378.
https://doi.org/10.1158/0008-5472.CAN-06-0402
Published: 15 June 2006
View article titled, Restoration of Tamoxifen Sensitivity in Estrogen Receptor–Negative Breast Cancer Cells: Tamoxifen-Bound Reactivated ER Recruits Distinctive Corepressor Complexes
Open the PDF for Restoration of Tamoxifen Sensitivity in Estrogen Receptor–Negative Breast Cancer Cells: Tamoxifen-Bound Reactivated ER Recruits Distinctive Corepressor Complexes in another window
Journal Articles

Homozygous deletion of LKB1 mutation in H157 lung cancer cell line

Diansheng Zhong, Lizheng Guo, Itziar de Aguirre, Xiuju Liu, Neil Lamb, Shiyong Sun, Anthony Gal, Paula M Vertino, Wei Zhou
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 49.
Published: 15 April 2006
View article titled, Homozygous deletion of LKB1 mutation in H157 lung cancer cell line
Journal Articles

Role of TMS1 in detachment-induced apoptosis

Melissa J. Parsons, Paula M. Vertino
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 580.
Published: 15 April 2006
View article titled, Role of TMS1 in detachment-induced apoptosis