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Journal Articles

Abstract 5729: Dynamic phase separation of the androgen receptor and its coactivators to regulate gene expression

Cancer Res (2022) 82 (12_Supplement): 5729.

https://doi.org/10.1158/1538-7445.AM2022-5729

Published: 15 June 2022

View articletitled, Abstract 5729: Dynamic phase separation of the androgen receptor and its coactivators to regulate gene expression

Journal Articles

Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression

Nora Pällmann, Ke Deng, Marte Livgård, Martina Tesikova, Yixin Jin, Nicolai Sebastian Frengen, Nermin Kahraman, Hamada M. Mokhlis, Bulent Ozpolat, Wanja Kildal, Havard Emil Danielsen, Ladan Fazli, Paul S. Rennie, Partha P. Banerjee, Aykut Üren, Yang Jin, Omer F. Kuzu, Fahri Saatcioglu

Cancer Res (2021) 81 (15): 4066–4078.

https://doi.org/10.1158/0008-5472.CAN-20-3956

Published: 01 August 2021

View articletitled, Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression

Includes: Supplementary data

Journal Articles

Abstract IA21: AR is ablated: Now what? Targeting the double-negative phenotype

Cancer Res (2018) 78 (16_Supplement): IA21.

https://doi.org/10.1158/1538-7445.PRCA2017-IA21

Published: 14 August 2018

View articletitled, Abstract IA21: AR is ablated: Now what? Targeting the double-negative phenotype

Journal Articles

Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3

Zahid M. Delwar, Yvonne Kuo, Yan H. Wen, Paul S. Rennie, William Jia

Cancer Res (2018) 78 (3): 718–730.

https://doi.org/10.1158/0008-5472.CAN-17-0599

Published: 31 January 2018

View articletitled, Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3

Includes: Supplementary data

Journal Articles

Abstract 130: Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer

Cancer Res (2017) 77 (13_Supplement): 130.

https://doi.org/10.1158/1538-7445.AM2017-130

Published: 01 July 2017

View articletitled, Abstract 130: Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer

Journal Articles

Abstract 1834: Semaphorin 3C is an androgen receptor-regulated gene

Kevin J. Tam, Kush Dalal, Michael Hsing, Chi Wing Cheng, Yan Ting Chiang, Aishwariya Sharma, James W. Peacock, Artem Cherkasov, Yuzhuo Wang, Martin E. Gleave, Paul S. Rennie, Christopher J. Ong

Cancer Res (2016) 76 (14_Supplement): 1834.

https://doi.org/10.1158/1538-7445.AM2016-1834

Published: 15 July 2016

View articletitled, Abstract 1834: Semaphorin 3C is an androgen receptor-regulated gene

Journal Articles

Abstract 4644: Inhibition of the androgen receptor at two drug-targetable sites on the DNA-binding domain protein surface

Kush Dalal, Aishwariya Sharma, Mani Roshan-Moniri, Hendrik Borgmann, Nada Lallous, Shannon Awrey, Huifang Li, Fuqiang Ban, Eric LeBlanc, Artem Cherkasov, Paul S. Rennie

Cancer Res (2016) 76 (14_Supplement): 4644.

https://doi.org/10.1158/1538-7445.AM2016-4644

Published: 15 July 2016

View articletitled, Abstract 4644: Inhibition of the androgen receptor at two drug-targetable sites on the DNA-binding domain protein surface

Journal Articles

Abstract 1727: DNA-binding domain as an alternative target site on androgen receptor for prostate cancer therapy: Pre-clinical in vivo study of a novel small molecule for drug development

Mohamed DH Hassona, Leslie G. Chan, Gray R. Meckling, Huifang Li, Eric LeBlanc, Fuqiang Ban, Artem Cherkasov, Paul S. Rennie, Emma Guns

Cancer Res (2015) 75 (15_Supplement): 1727.

https://doi.org/10.1158/1538-7445.AM2015-1727

Published: 01 August 2015

View articletitled, Abstract 1727: DNA-binding domain as an alternative target site on androgen receptor for prostate cancer therapy: Pre-clinical in vivo study of a novel small molecule for drug development

Journal Articles

Abstract 1778: Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer

Kush Dalal, Mani Roshan-Moniri, Aishwariya Sharma, Huifang Li, Fuqiang Ban, Mohamed D. Hassona, Michael Hsing, Kriti Singh, Eric LeBlanc, Scott Dehm, Emma Tomlinson Guns, Artem Cherkasov, Paul S. Rennie

Cancer Res (2015) 75 (15_Supplement): 1778.

https://doi.org/10.1158/1538-7445.AM2015-1778

Published: 01 August 2015

View articletitled, Abstract 1778: Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer

Journal Articles

Abstract 3653: Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors

Huifang Li, Nada Lallous, Kush Dalal, Eric Leblanc, Fuqiang Ban, Fabrice Ciesielski, Paul S. Rennie, Artem Cherkasov

Cancer Res (2015) 75 (15_Supplement): 3653.

https://doi.org/10.1158/1538-7445.AM2015-3653

Published: 01 August 2015

View articletitled, Abstract 3653: Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors

Journal Articles

Abstract 1652: Therapeutic targeting of ETS factor ERG for the treatment of prostate cancer

Mani Roshan-Moniri, Michael Hsing, Miriam S. Butler, Desmond Lau, Peter Axerio-Cilies, Paul Yen, Ari Kim, Scott Lien, Marta Mroczek, Dennis Ma, Huifang Li, Yubin Guo, Fuqiang Ban, Fariba Ghaidi, Eric LeBlanc, Lawrence McIntosh, Michael Cox, Artem Cherkasov, Paul S. Rennie

Cancer Res (2015) 75 (15_Supplement): 1652.

https://doi.org/10.1158/1538-7445.AM2015-1652

Published: 01 August 2015

View articletitled, Abstract 1652: Therapeutic targeting of ETS factor ERG for the treatment of prostate cancer

Journal Articles

Abstract 1648: Targeting ETS factor ETV4 as a novel therapeutic for the management of breast and prostate cancer

Miriam S. Butler, Michael Hsing, Mani Roshan Moniri, Desmond Lau, Paul Yen, Ari Kim, Scott Lien, Marta Mroczek, Fariba Ghaidi, Eric LeBlanc, Lawrence McIntosh, Michael Cox, Artem Cherkasov, Paul S. Rennie

Cancer Res (2015) 75 (15_Supplement): 1648.

https://doi.org/10.1158/1538-7445.AM2015-1648

Published: 01 August 2015

View articletitled, Abstract 1648: Targeting ETS factor ETV4 as a novel therapeutic for the management of breast and prostate cancer

Journal Articles

Abstract 3651: The development of anti-estrogens targeting the activation function 2 site of estrogen receptor alpha for treatment of Tamoxifen resistant breast cancer

Kriti Singh, Ravi Shashi Nayana Munuganti, Eric Leblanc, Artem Cherkasov, Paul S. Rennie

Cancer Res (2015) 75 (15_Supplement): 3651.

https://doi.org/10.1158/1538-7445.AM2015-3651

Published: 01 August 2015

View articletitled, Abstract 3651: The development of anti-estrogens targeting the activation function 2 site of estrogen receptor alpha for treatment of Tamoxifen resistant breast cancer

Journal Articles

Abstract 3654: Targeting binding function-3 site on the androgen receptor to treat Enzalutamide-resistant prostate cancer

Ravi Shashi Nayana Munuganti, Mohamed DH Hassona, Eric Leblanc, Emma T. Guns, Paul S. Rennie, Artem Cherkasov

Cancer Res (2015) 75 (15_Supplement): 3654.

https://doi.org/10.1158/1538-7445.AM2015-3654

Published: 01 August 2015

View articletitled, Abstract 3654: Targeting binding function-3 site on the androgen receptor to treat Enzalutamide-resistant prostate cancer

Journal Articles

Abstract PD6-7: In-silico discovery of novel estrogen receptor-α inhibitors as potential therapeutics for tamoxifen resistant breast cancer

Kriti Singh, Ravi SN Munuganti, Miriam Butler, Artem Cherkasov, Paul S Rennie

Cancer Res (2015) 75 (9_Supplement): PD6-7.

https://doi.org/10.1158/1538-7445.SABCS14-PD6-7

Published: 01 May 2015

View articletitled, Abstract PD6-7: In-silico discovery of novel estrogen receptor-α inhibitors as potential therapeutics for tamoxifen resistant breast cancer

Journal Articles

Abstract 1632: Discovery of a novel series of androgen receptor antagonists with potential therapeutic applications in castration-resistant prostate cancer

Huifang Li, Mohamed DH Hassona, Nathan A. Lack, Peter Axerio-Cilies, Eric Leblanc, Emma T. Guns, Paul S. Rennie, Artem Cherkasov

Cancer Res (2014) 74 (19_Supplement): 1632.

https://doi.org/10.1158/1538-7445.AM2014-1632

Published: 01 October 2014

View articletitled, Abstract 1632: Discovery of a novel series of androgen receptor antagonists with potential therapeutic applications in castration-resistant prostate cancer

Journal Articles

Abstract 1235: Targeting the DNA binding domain of the androgen receptor as a potential therapy for prostate cancer

Kush Dalal, Huifang Li, Mani R. Moniri, Fuqiang Ban, Aishwariya Sharma, Artem Cherkasov, Paul S. Rennie

Cancer Res (2014) 74 (19_Supplement): 1235.

https://doi.org/10.1158/1538-7445.AM2014-1235

Published: 01 October 2014

View articletitled, Abstract 1235: Targeting the DNA binding domain of the androgen receptor as a potential therapy for prostate cancer

Journal Articles

Abstract 2521: Small molecule inhibitors targeting the activation function-2 site of estrogen receptor-α

Kriti Singh, Ravi Shashi Nayana Munuganti, Eric Leblanc, Artem Cherkasov, Paul S. Rennie

Cancer Res (2014) 74 (19_Supplement): 2521.

https://doi.org/10.1158/1538-7445.AM2014-2521

Published: 01 October 2014

View articletitled, Abstract 2521: Small molecule inhibitors targeting the activation function-2 site of estrogen receptor-α

Journal Articles

Abstract 2508: The development of anti-androgens with a novel mechanism of action for treatment of castration-resistant prostate cancer

Ravi Shashi Nayana Munuganti, Mohamed DH Hassona, Eric Leblanc, Fuqiang Ban, Emma T. Guns, Paul S. Rennie, Artem Cherkasov

Cancer Res (2014) 74 (19_Supplement): 2508.

https://doi.org/10.1158/1538-7445.AM2014-2508

Published: 01 October 2014

View articletitled, Abstract 2508: The development of anti-androgens with a novel mechanism of action for treatment of castration-resistant prostate cancer

Journal Articles

Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications

Laurent Grosse, Sophie Pâquet, Patrick Caron, Ladan Fazli, Paul S. Rennie, Alain Bélanger, Olivier Barbier

Cancer Res (2013) 73 (23): 6963–6971.

https://doi.org/10.1158/0008-5472.CAN-13-1462

Published: 01 December 2013

View articletitled, Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications

Includes: Supplementary data

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Abstract 5729: Dynamic phase separation of the androgen receptor and its coactivators to regulate gene expression

Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression

Abstract IA21: AR is ablated: Now what? Targeting the double-negative phenotype

Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3

Abstract 130: Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer

Abstract 1834: Semaphorin 3C is an androgen receptor-regulated gene

Abstract 4644: Inhibition of the androgen receptor at two drug-targetable sites on the DNA-binding domain protein surface

Abstract 1727: DNA-binding domain as an alternative target site on androgen receptor for prostate cancer therapy: Pre-clinical in vivo study of a novel small molecule for drug development

Abstract 1778: Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer

Abstract 3653: Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors

Abstract 1652: Therapeutic targeting of ETS factor ERG for the treatment of prostate cancer

Abstract 1648: Targeting ETS factor ETV4 as a novel therapeutic for the management of breast and prostate cancer

Abstract 3651: The development of anti-estrogens targeting the activation function 2 site of estrogen receptor alpha for treatment of Tamoxifen resistant breast cancer

Abstract 3654: Targeting binding function-3 site on the androgen receptor to treat Enzalutamide-resistant prostate cancer

Abstract PD6-7: In-silico discovery of novel estrogen receptor-α inhibitors as potential therapeutics for tamoxifen resistant breast cancer

Abstract 1632: Discovery of a novel series of androgen receptor antagonists with potential therapeutic applications in castration-resistant prostate cancer

Abstract 1235: Targeting the DNA binding domain of the androgen receptor as a potential therapy for prostate cancer

Abstract 2521: Small molecule inhibitors targeting the activation function-2 site of estrogen receptor-α

Abstract 2508: The development of anti-androgens with a novel mechanism of action for treatment of castration-resistant prostate cancer

Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications

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