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Journal Articles

Retraction: Cytokines Modulate Telomerase Activity in a Human Multiple Myeloma Cell Line

Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, Yu-Tzu Tai, Constantine S. Mitsiades, Nicholas Mitsiades, Dharminder Chauhan, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 940.
https://doi.org/10.1158/0008-5472.CAN-24-0516
Published: 15 March 2024
View article titled, Retraction: Cytokines Modulate Telomerase Activity in a Human Multiple Myeloma Cell Line
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Journal Articles

Retraction: Nuclear Factor-κB p65 Mediates Tumor Necrosis Factor α-induced Nuclear Translocation of Telomerase Reverse Transcriptase Protein

Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, Yu-Tzu Tai, Constantine S. Mitsiades, Nicholas Mitsiades, Dharminder Chauhan, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 939.
https://doi.org/10.1158/0008-5472.CAN-24-0517
Published: 15 March 2024
View article titled, Retraction: Nuclear Factor-κB p65 Mediates Tumor Necrosis Factor α-induced Nuclear Translocation of Telomerase Reverse Transcriptase Protein
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Journal Articles

Retraction: Effects of Oligonucleotide N3′→P5′ Thio-phosphoramidate (GRN163) Targeting Telomerase RNA in Human Multiple Myeloma Cells

Masaharu Akiyama, Teru Hideshima, Masood A. Shammas, Toshiaki Hayashi, Makoto Hamasaki, Yu-Tzu Tai, Paul Richardson, Sergei Gryaznov, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 937.
https://doi.org/10.1158/0008-5472.CAN-24-0518
Published: 15 March 2024
View article titled, Retraction: Effects of Oligonucleotide N3′→P5′ Thio-phosphoramidate (GRN163) Targeting Telomerase RNA in Human Multiple Myeloma Cells
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Journal Articles

Retraction: Insulin-like Growth Factor-1 Induces Adhesion and Migration in Human Multiple Myeloma Cells via Activation of β1-Integrin and Phosphatidylinositol 3′-Kinase/AKT Signaling

Yu-Tzu Tai, Klaus Podar, Laurence Catley, Yu-Hua Tseng, Masaharu Akiyama, Reshma Shringarpure, Renate Burger, Teru Hideshima, Dharminder Chauhan, Nicholas Mitsiades, Paul Richardson, Nikhil C. Munshi, C. Ronald Kahn, Constantine Mitsiades, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 938.
https://doi.org/10.1158/0008-5472.CAN-24-0519
Published: 15 March 2024
View article titled, Retraction: Insulin-like Growth Factor-1 Induces Adhesion and Migration in Human Multiple Myeloma Cells via Activation of β1-Integrin and Phosphatidylinositol 3′-Kinase/AKT Signaling
Open the PDF for Retraction: Insulin-like Growth Factor-1 Induces Adhesion and Migration in Human Multiple Myeloma Cells via Activation of β1-Integrin and Phosphatidylinositol 3′-Kinase/AKT Signaling in another window
Journal Articles

Retraction: Mechanisms by which SGN-40, a Humanized Anti-CD40 Antibody, Induces Cytotoxicity in Human Multiple Myeloma Cells: Clinical Implications

Yu-Tzu Tai, Laurence P. Catley, Constantine S. Mitsiades, Renate Burger, Klaus Podar, Reshma Shringpaure, Teru Hideshima, Dharminder Chauhan, Makoto Hamasaki, Kenji Ishitsuka, Paul Richardson, Steven P. Treon, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 936.
https://doi.org/10.1158/0008-5472.CAN-24-0520
Published: 15 March 2024
View article titled, Retraction: Mechanisms by which SGN-40, a Humanized Anti-CD40 Antibody, Induces Cytotoxicity in Human Multiple Myeloma Cells: Clinical Implications
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Journal Articles

Abstract 1843: Melflufen efficacy in multiple myeloma with TP53 aberrations

Ana Slipicevic, Umair Munawar, Thorsten Stühmer, Johan Aschan, Fredrik Lehmann, Nina N. Nupponen, Juho Miettinen, Maiju-Emilia Huppunen, Caroline A. Heckman, María-Victoria Mateos, Paula Rodríguez Otero, Paul Richardson, Ralf Bargou
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1843.
https://doi.org/10.1158/1538-7445.AM2020-1843
Published: 15 August 2020
View article titled, Abstract 1843: Melflufen efficacy in multiple myeloma with <em>TP53</em> aberrations
Journal Articles

Abstract 3832: A proliferation-inducing ligand (APRIL) directly impacts immune regulatory subsets to regulate suppressive multiple myeloma bone marrow microenvironment

Yu-Tzu Tai, Liang Lin, Liji Xing, Liji Xing, Kenneth Wen, Nikhil Munshi, Paul Richardson, Kenneth Anderson
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3832.
https://doi.org/10.1158/1538-7445.AM2018-3832
Published: 01 July 2018
View article titled, Abstract 3832: A proliferation-inducing ligand (APRIL) directly impacts immune regulatory subsets to regulate suppressive multiple myeloma bone marrow microenvironment
Journal Articles

Abstract 972: B-cell maturation antigen (BCMA) activation in human multiple myeloma cells promotes myeloma cell growth and survival in the bone marrow microenvironment via upregulated MCL-1 and NFκB signaling

Yu-Tzu Tai, Chirag Acharya, Mike Y. Zhong, Michele Cea, Antonia Cagnetta, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 972.
https://doi.org/10.1158/1538-7445.AM2014-972
Published: 01 October 2014
View article titled, Abstract 972: B-cell maturation antigen (BCMA) activation in human multiple myeloma cells promotes myeloma cell growth and survival in the bone marrow microenvironment via upregulated MCL-1 and NFκB signaling
Journal Articles

Abstract 638: Lenalidomide treatment enhances the anti-tumor activities of XBP1 specific cytotoxic T lymphocytes by increasing the frequency and tumor-specific response of central memory CD3+CD8+ T cells

Jooeun Bae, Rao Prabhala, Ruben Carrasco, Paul Richardson, Glen Dranoff, Kenneth C. Anderson, Nikhil C. Munshi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 638.
https://doi.org/10.1158/1538-7445.AM2014-638
Published: 01 October 2014
View article titled, Abstract 638: Lenalidomide treatment enhances the anti-tumor activities of XBP1 specific cytotoxic T lymphocytes by increasing the frequency and tumor-specific response of central memory CD3+CD8+ T cells
Journal Articles

Abstract 644: Novel anti-B cell maturation antigen-monomethyl auristatin F antibody-drug conjugate (GSK2857916) induces potent and selective anti-multiple myeloma activity via enhanced effector function and direct tumor cell killing

Yu-Tzu Tai, Chirag Acharya, Mike Y. Zhong, Michele Cea, Antonia Cagnetta, Patrick A. Mayes, Jenny Craigen, Louise Gliddon, James Smothers, Amanda L. Christie, Andrew L. Kung, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 644.
https://doi.org/10.1158/1538-7445.AM2014-644
Published: 01 October 2014
View article titled, Abstract 644: Novel anti-B cell maturation antigen-monomethyl auristatin F antibody-drug conjugate (GSK2857916) induces potent and selective anti-multiple myeloma activity via enhanced effector function and direct tumor cell killing
Journal Articles

Abstract 2142: The nuclear export protein CRM1 (XPO1) regulates multiple myeloma cell growth, osteoclastogenesis, and myeloma-induced osteolysis.

Yu-Tzu Tai, Yosef Landesman, Chirag Acharya, Yolanda Calle, Mike Zhong, Michele Cea, Daniel Tannenbaum, Antonia Cagnetta, Michaela Reagan, Aditya Munshi, William Senapedis, Jean-Richard Saint-Martin, Trinayan Kashyap, Sharon Shacham, Michael Kauffman, Yumei Gu, Lizi Wu, Steve Schey, Irene Ghobrial, Andrew Kung, Nikhil Munshi, Paul Richardson, Kenneth Anderson, Haoqiang Ying
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2142.
https://doi.org/10.1158/1538-7445.AM2013-2142
Published: 15 April 2013
View article titled, Abstract 2142: The nuclear export protein CRM1 (XPO1) regulates multiple myeloma cell growth, osteoclastogenesis, and myeloma-induced osteolysis.
Journal Articles

Abstract 2934: Targeting Bruton's tyrosine kinase with PCI-32765 blocks growth and survival of multiple myeloma and Waldenström macroglobulinemia via potent inhibition of osteoclastogenesis, cytokines/chemokine secretion, and myeloma stem-like cells in the bone marrow microenvironment

Yu-Tzu Tai, Betty Chang, Sun-Young Kong, Mariateresa Fulciniti, Guang Yang, Yolanda Calle, Yiguo Hu, Jianhong Lin, Jian-Jun Zhao, Antonia Cagnetta, Michele Cea, Michael Sellitto, Michelle Chen, Daniel R. Carrasco, Laurence Elias, Joseph Buggy, Steven P. Treon, Zachary Hunter, William Matsui, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2934.
https://doi.org/10.1158/1538-7445.AM2012-2934
Published: 15 April 2012
View article titled, Abstract 2934: Targeting Bruton's tyrosine kinase with PCI-32765 blocks growth and survival of multiple myeloma and Waldenström macroglobulinemia via potent inhibition of osteoclastogenesis, cytokines/chemokine secretion, and myeloma stem-like cells in the bone marrow microenvironment
Journal Articles

Abstract #3695: Targeting MEK1/2 signaling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo

Yu-Tzu Tai, Kihyun Kim, Mariateresa Fulciniti, Ender Soydan, Weihua Song, Xian-Feng Li, Matthew Rumizen, Sabikun Nahar, Peter Burger, Teru Hideshima, Paul Richardson, Nikhil Munshi, Ann Clark, Andreas Goutopoulos, Luca Rastelli, Kenneth Kenneth
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3695.
Published: 01 May 2009
View article titled, Abstract #3695: Targeting MEK1/2 signaling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo
Journal Articles

The sequence analysis of β-subunit genes of the 20S proteasome in tumor tissue

David Lichter, Michael Pickard, Eric Lightcap, Olga Tayber, William Trepicchio, George Mulligan, Andy Boral, Paul Richardson, Kenneth Anderson, Melissa Alsina, William Dalton, Pieter Sonneveld, Hadi Danaee
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4805.
Published: 01 May 2008
View article titled, The sequence analysis of β-subunit genes of the 20S proteasome in tumor tissue
Journal Articles

Clues from the MMRC Genomics Initiative about the multiple myeloma druggable genome

Daniel Auclair, Jonathan Keats, John Carpten, Mike Chapman, Suzanne Trudel, David Seigel, S. Vincent Rajkumar, Melissa Alsina, Paul Richardson, Kenneth Anderson, Rafael Fonseca, Todd Golub, Jeffrey Trent, Louise Perkins
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4130.
Published: 01 May 2008
View article titled, Clues from the MMRC Genomics Initiative about the multiple myeloma druggable genome
Journal Articles

Inhibition of MAPK/ERK1/2 activity by MEK1/2 inhibitor AZD6244 (ARRY-142886) induces human multiple myeloma (MM) cell apoptosis and blocks MM interactions within the bone marrow microenvironment: a new therapeutic strategy for MM

Yu-Tzu Tai, Teru Hideshima, Weihua Song, Xian-Feng Li, Matthew Rumizen, Peter Burger, Aileen Morrison, Klaus Podar, Robert Schlossman, Paul Richardson, Nikhil Munshi, Irene Ghobria, Paul Smith, Kenneth Anderson
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3242.
Published: 01 May 2007
View article titled, Inhibition of MAPK/ERK1/2 activity by MEK1/2 inhibitor AZD6244 (ARRY-142886) induces human multiple myeloma (MM) cell apoptosis and blocks MM interactions within the bone marrow microenvironment: a new therapeutic strategy for MM
Journal Articles

Modulation of heparanase expression in myeloma tumor cell lines by defibrotide: A novel mechanism of anti-tumor activity

Cinara Echart, Maria Distaso, Cinzia Repice, Antonio Palumbo, Constantine Mitsiades, Paul Richardson, Kenneth Anderson, Massimo Iacobelli
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3100.
Published: 01 May 2007
View article titled, Modulation of heparanase expression in myeloma tumor cell lines by defibrotide: A novel mechanism of anti-tumor activity
Journal Articles

Role of B-Cell–Activating Factor in Adhesion and Growth of Human Multiple Myeloma Cells in the Bone Marrow Microenvironment

Yu-Tzu Tai, Xian-Feng Li, Iris Breitkreutz, Weihua Song, Paola Neri, Laurence Catley, Klaus Podar, Teru Hideshima, Dharminder Chauhan, Noopur Raje, Robert Schlossman, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2006) 66 (13): 6675–6682.
https://doi.org/10.1158/0008-5472.CAN-06-0190
Published: 03 July 2006
View article titled, Role of B-Cell–Activating Factor in Adhesion and Growth of Human Multiple Myeloma Cells in the Bone Marrow Microenvironment
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Journal Articles

Role of BAFF in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment

Yu-Tzu Tai, Xian-Feng Li, Rory Coffey, Laurence Catley, Klaus Podar, Teru Hideshima, Dharminder Chauhan, Noopur Raje, Robert Schlossman, Paul Richardson, Nikhil Munshi, Kenneth Anderson
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1132.
Published: 15 April 2006
View article titled, Role of BAFF in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment
Journal Articles

Pharmacodynamic profiling defines the significant biological activities of the novel proteasome inhibitor NPI-0052: Comparison with Velcade® (Bortezomib)

Ta-Hsiang Chao, Dharminder Chauhan, Gordafaried Deyanat-Yazdi, Laurence Catley, Paul Richardson, G. Kenneth Lloyd, Saskia T. C. Neuteboom, Kenneth C. Anderson, Michael A. Palladino
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1141.
Published: 15 April 2006
View article titled, Pharmacodynamic profiling defines the significant biological activities of the novel proteasome inhibitor NPI-0052: Comparison with Velcade<sup>®</sup> (Bortezomib)