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Journal Articles

Abstract 7321: Second primary cancer risks following breast cancer in BRCA1/2 pathogenic variant carriers

Isaac Allen, Hend Hassan, Yvonne Walburga, Catherine Huntley, Lucy Loong, Tameera Rahman, Beth Torr, Andrew Bacon, Craig Knott, Sophie Jose, Sally Vernon, Margreet Lüchtenborg, Joanna Pethick, Francesco Santaniello, Shilpi Goel, Sophie Allen, Katrina Lavelle, Fiona McRonald, Diana M. Eccles, Eva Morris, Steven Hardy, Clare Turnbull, Marc Tischkowitz, Paul Pharoah, Antonis C. Antoniou
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7321.
https://doi.org/10.1158/1538-7445.AM2024-7321
Published: 22 March 2024
View article titled, Abstract 7321: Second primary cancer risks following breast cancer in <em>BRCA1/2</em> pathogenic variant carriers
Journal Articles

Abstract A004: Patterns of lncRNA-regulated gene expression in high-grade serous ovarian carcinomas

Brett M. Reid, Ann Chen, Zhihua Chen, Florian A. Karreth, Peter Kanetsky, Jennifer B. Permuth, Ozlen Saglam, Jamie K. Teer, Xiaoqing Yu, Simon Gayther, Ellen Goode, Paul Pharoah, Thomas A. Sellers, Kate Lawrenson, Jonathan Tyrer
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): A004.
https://doi.org/10.1158/1538-7445.OVARIAN23-A004
Published: 04 March 2024
View article titled, Abstract A004: Patterns of lncRNA-regulated gene expression in high-grade serous ovarian carcinomas
Journal Articles

Abstract 6065: Patterns of dysregulated coding and noncoding gene expression in high-grade serous ovarian carcinomas

Brett M. Reid, Ann Chen, Zhihua Chen, Florian A. Karreth, Peter Kanetsky, Jennifer B. Permuth, Ozlen Saglam, Jamie Teer, Xiaoqing Yu, Simon Gayther, Ellen Goode, Paul Pharoah, Thomas A. Sellers, Kate Lawrenson
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6065.
https://doi.org/10.1158/1538-7445.AM2023-6065
Published: 04 April 2023
View article titled, Abstract 6065: Patterns of dysregulated coding and noncoding gene expression in high-grade serous ovarian carcinomas
Journal Articles

Abstract 3057: Second primary cancer risks for female and male breast cancer survivors

Isaac Allen, Tameera Rahman, Andrew Bacon, Craig Knott, Sophie Jose, Sally Vernon, Hend Hassan, Catherine Huntley, Lucy Loong, Yvonne Walburga, Katrina Lavelle, Eva Morris, Steven Hardy, Beth Torr, Diana Eccles, Clare Turnbull, Marc Tischkowitz, Paul Pharoah, Antonis C. Antoniou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3057.
https://doi.org/10.1158/1538-7445.AM2023-3057
Published: 04 April 2023
View article titled, Abstract 3057: Second primary cancer risks for female and male breast cancer survivors
Journal Articles

Abstract 988: Long-term health outcomes of bilateral salpingo-oophorectomy in women with personal history of breast cancer

Hend Hassan, Tameera Rahman, Andrew Bacon, Craig Knott, Isaac Allen, Catherine Huntley, Lucy Loong, Yvonne Walburga, Katrina Lavelle, Eva Morris, Steven Hardy, Bethany Torr, Diana M Eccles, Clare Turnbull, Marc Tischkowitz, Paul Pharoah, Antonis C. Antoniou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 988.
https://doi.org/10.1158/1538-7445.AM2023-988
Published: 04 April 2023
View article titled, Abstract 988: Long-term health outcomes of bilateral salpingo-oophorectomy in women with personal history of breast cancer
Journal Articles

Abstract 5227: Cross-trait genome-wide association meta-analyses of clonal hematopoiesis and solid tumor risk

Victoria Gray, George Richenberg, Pedro Quirós, Matthew Freedman, Paul Pharoah, Simon Gayther, Michelle Jones, George Vassiliou, Kate Lawrenson, Siddhartha Kar
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5227.
https://doi.org/10.1158/1538-7445.AM2023-5227
Published: 04 April 2023
View article titled, Abstract 5227: Cross-trait genome-wide association meta-analyses of clonal hematopoiesis and solid tumor risk
Journal Articles

Abstract OT2-10-02: Mypebs: An international randomized study comparing personalized, risk-stratified to standard breast cancer screening in women aged 40-70

Suzette Delaloge, Paolo Giorgi Rossi, Michal Guindy, Fiona Gilbert, Jean-Benoit Burrion, Corinne Balleyguier, Marta Roman Exposito, Livia Giordano, Harry De Koning, Sandrine de Montgolfier, Stephane Ragusa, Damien Drubay, Marie-Eve Rouge-Bugat, Gareth D Evans, Debbie Keatley, Helene Blanche, Anne Boland, Emilien Gauthier, Aloys Dubois d'Aische, Cécile Vissac-Sabatier, Daniel Couch, Camille Baron, Jean-François Deleuze, Paul Pharoah, Stefan Michiels
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): OT2-10-02.
https://doi.org/10.1158/1538-7445.SABCS21-OT2-10-02
Published: 15 February 2022
View article titled, Abstract OT2-10-02: Mypebs: An international randomized study comparing personalized, risk-stratified to standard breast cancer screening in women aged 40-70
Journal Articles

Abstract 30: Cross-cancer cross-tissue transcriptome-wide association study (TWAS) of 11 cancers identifies 56 novel genes

Helian Feng, Arunabha Majumdar, Bogdan Pasaniuc, Hongjie Chen, Sara Lindström, BCAC, OCAC, PRACTICAL, Jeroen Huyghe, Stephanie L. Schmit, Tracy A. O'Mara, Deborah J. Thompson, Stuart MacGregor, Paul Brennan, James McKay, Richard S. Houlston, Beatrice S. Melin, Christopher Amos, Anne E. Cus, Mark M. Iles, Siddhartha Kar, Paul Pharoah, Rayjean J. Hung, Peter Kraft
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 30.
https://doi.org/10.1158/1538-7445.AM2020-30
Published: 15 August 2020
View article titled, Abstract 30: Cross-cancer cross-tissue transcriptome-wide association study (TWAS) of 11 cancers identifies 56 novel genes
Journal Articles

Abstract 3523: MRI-first screening for prostate cancer: A benefit-harm and cost-effectiveness analysis

Thomas Callender, Mark Emberton, Steve Morris, Paul Pharoah, Nora Pashayan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3523.
https://doi.org/10.1158/1538-7445.AM2020-3523
Published: 15 August 2020
View article titled, Abstract 3523: MRI-first screening for prostate cancer: A benefit-harm and cost-effectiveness analysis
Journal Articles

Abstract 1194: Cross-cancer GWAS meta-analysis of more than 370,000 cases and 530,000 controls identifies multiple novel cancer risk regions

Sara Lindström, Siddhartha Kar, Lu Wang, Constance Turman, James MacDonald, Theo Bammler, BCAC, OCAC, PRACTICAL, Jeroen Huyghe, Stephanie Schmit, Tracy A. O'Mara, Deborah J. Thompson, Puya Gharahkhani, Stuart MacGregor, Paul Brennan, Richard S. Houlston, Beatrice S. Melin, Christopher I. Amos, James McKay, Mark M. Iles, Matthew H. Law, Alison Klein, Laufey Amundadottir, Bogdan Pasaniuc, Paul Pharoah, Rayjean J. Hung, Peter Kraft
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1194.
https://doi.org/10.1158/1538-7445.AM2020-1194
Published: 15 August 2020
View article titled, Abstract 1194: Cross-cancer GWAS meta-analysis of more than 370,000 cases and 530,000 controls identifies multiple novel cancer risk regions
Journal Articles

Abstract 5703: Oncologic therapy shapes the fitness landscape of clonal hematopoiesis

Kelly L. Bolton, Ryan N. Ptashkin, Teng Gao, Lior Braunstein, Sean M. Devlin, Minal Patel, Antonin Berthon, Aijazuddin Syed, Mariko Yabe, Catherine Coombs, Nicole M. Caltabellotta, Mike Walsh, Ken Offit, Zsofia Stadler, Choonsik Lee, Paul Pharoah, Konrad H. Stopsack, Barbara Spitzer, Simon Mantha, James Fagin, Laura Boucai, Christopher J. Gibson, Benjamin Ebert, Andrew L. Young, Todd Druley, Koichi Takahashi, Nancy Gillis, Markus Ball, Eric Padron, David Hyman, Jose Baselga, Larry Norton, Stuart Gardos, Virginia Klimek, Howard Scher, Dean Bajorin, Eder Paraiso, Ryma Benayed, Maria Arcilla, Marc Ladanyi, David Solit, Michael Berger, Martin Tallman, Montserrat Garcia-Closas, Nilanjan Chatterjee, Luis Diaz, Ross Levine, Lindsay Morton, Ahmet Zehir, Elli Papaemmanuil
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5703.
https://doi.org/10.1158/1538-7445.AM2020-5703
Published: 15 August 2020
View article titled, Abstract 5703: Oncologic therapy shapes the fitness landscape of clonal hematopoiesis
Journal Articles

Abstract 4976: Combining measures of immune infiltration uncovers predictors of survival in high-grade serous ovarian cancer

Anne Montfort, Steph J. Owen, Anna M. Piskorz, Anna Supernat, Luiza Moore, Sarwah Al-Khalidi, Steffen Boehm, Paul Pharoah, Jacqueline McDermott, Frances R. Balkwill, James D. Brenton
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4976.
https://doi.org/10.1158/1538-7445.AM2020-4976
Published: 15 August 2020
View article titled, Abstract 4976: Combining measures of immune infiltration uncovers predictors of survival in high-grade serous ovarian cancer
Journal Articles

Abstract 2415: Polygenic risk-tailored screening for prostate cancer: A cost-effectiveness analysis

Thomas Callender, Mark Emberton, Steve Morris, Ros Eeles, Zsofia Kote-Jarai, Paul Pharoah, Nora Pashayan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2415.
https://doi.org/10.1158/1538-7445.AM2019-2415
Published: 01 July 2019
View article titled, Abstract 2415: Polygenic risk-tailored screening for prostate cancer: A cost-effectiveness analysis
Journal Articles

Abstract 2271: Pathway analysis suggests biological processes driven by germline genetic associations with breast cancer prognosis

Maria Escala Garcia, Qi Guo, Lodewyk Wessels, Gary Bader, Paul Pharoah, Georgia Chenevix-Trench, Douglas Easton, Sander Canisius, Marjanka Schmidt
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2271.
https://doi.org/10.1158/1538-7445.AM2018-2271
Published: 01 July 2018
View article titled, Abstract 2271: Pathway analysis suggests biological processes driven by germline genetic associations with breast cancer prognosis
Journal Articles

Abstract 2211: Patient level polygenic risk scores and continuous estrogen receptor expression in breast cancer

Anamay H. Shetty, Raza Ali, Fiona Blows, Carlos Caldas, Nicholas Inard, Javier Benítez, Jenny Chang-Claude, Georgia Chenevix-Trench, Fergus Couch, Angela Cox, Peter Devilee, Douglas Easton, Montserrat Garcia-Closas, Arto Mannermaa, Heli Nevanlinna, Marjanka Schmidt, Paul Pharoah
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2211.
https://doi.org/10.1158/1538-7445.AM2018-2211
Published: 01 July 2018
View article titled, Abstract 2211: Patient level polygenic risk scores and continuous estrogen receptor expression in breast cancer
Journal Articles

Abstract 1225: Rare variants in DNA damage repair genes are associated with male breast cancer predisposition

Sarah L. Maguire, Katarzyna Tomczyk, Eleni Perrakis, Edward Saunders, Daniel Leongamornlert, ZSofia Kote-Jarai, Rosalind Eeles, Montserrat Garcia-Closas, Paul Pharoah, Douglas Easton, Christopher J. Lord, Alan Ashworth, Anthony Swerdlow, Nick Orr
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1225.
https://doi.org/10.1158/1538-7445.AM2018-1225
Published: 01 July 2018
View article titled, Abstract 1225: Rare variants in DNA damage repair genes are associated with male breast cancer predisposition
Journal Articles

Abstract 5502: Functional evaluation of superenhancers as mediators of epithelial ovarian cancer risk

Kevin C. Vavra, Simon Coetzee, Janet M. Lee, Paul Pharoah, Dennis J. Hazelett, Kate Lawrenson, Simon A. Gayther
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5502.
https://doi.org/10.1158/1538-7445.AM2017-5502
Published: 01 July 2017
View article titled, Abstract 5502: Functional evaluation of superenhancers as mediators of epithelial ovarian cancer risk
Journal Articles

Abstract 1308: Transcriptome-wide association study among 66,450 women to identify candidate susceptible genes for ovarian cancer risk

Yingchang Lu, Joellen M. Schildkraut, Thomas A. Sellers, Lang Wu, Xingyi Guo, Bingshan Li, Y. Ann Chen, Jennifer B. Doherty, Simon Gayther, Ellen L. Goode, Hae Kyung Im, Siddhartha Kar, Kate Lawrenson, Ani W. Manichaikul, Jennifer B. Permuth, Brett M. Reid, Jamie K. Teer, Paul Pharoah, Wei Zheng, Jirong Long
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1308.
https://doi.org/10.1158/1538-7445.AM2017-1308
Published: 01 July 2017
View article titled, Abstract 1308: Transcriptome-wide association study among 66,450 women to identify candidate susceptible genes for ovarian cancer risk
Journal Articles

Abstract 1299: Common germline risk loci and the tumor anticancer immune response in breast cancer

Siddhartha Kar, Jonathan Tyrer, Paul Pharoah, Breast Cancer Association Consortium (BCAC)
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1299.
https://doi.org/10.1158/1538-7445.AM2017-1299
Published: 01 July 2017
View article titled, Abstract 1299: Common germline risk loci and the tumor anticancer immune response in breast cancer
Journal Articles

Abstract 1289: Evaluation of vitamin D receptor regulated genes reveals EGFR polymorphism is associated with high-grade serous ovarian cancer in African American women

Delores J. Grant, Ani Manichaikul, Lauren C. Peres, Xin-Qun Wang, Ann G. Schwartz, Anna Wu, Edward Peters, Patricia Moorman, Michele L. Cote, Melissa Bondy, Linda E. Kelemen, Jill Barnholtz-Sloan, Temitope O. Keku, Cathrine Hoyo, Andrew Berchuck, Paul Pharoah, Joellen M. Schildkraut, African American Cancer Epidemiology Study (AACES) and the Ovarian Cancer Assoc Consortium (OCAC)
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1289.
https://doi.org/10.1158/1538-7445.AM2017-1289
Published: 01 July 2017
View article titled, Abstract 1289: Evaluation of vitamin D receptor regulated genes reveals EGFR polymorphism is associated with high-grade serous ovarian cancer in African American women