1-20 of 20
Paul Moore
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 1555: Enhanced HER2-dependent immune activation by margetuximab, an investigational Fc-engineered anti-HER2 mAb, supports combination with checkpoint blockade

Xiaoyu Zhang, Haiquan Li, Yinhua Yang, Qihong Xu, Tom Kaufman, Doug Smith, Jeffrey Nordstrom, Ezio Bonvini, Paul Moore
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1555.
DOI: https://doi.org/10.1158/1538-7445.AM2021-1555
Published: 01 July 2021
View article
Journal Articles

Abstract CT085: Pharmacodynamic correlates in a phase I study of INCMGA00012, a PD-1 antagonistic monoclonal antibody

Thomas Condamine, Sherry Owens, Patricia Feldman, Ross La Motte-Mohs, John Muth, Bradley Sumrow, Paul Moore, Robert Newton
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT085.
DOI: https://doi.org/10.1158/1538-7445.AM2019-CT085
Published: 01 July 2019
View article
Journal Articles

Abstract 1533: IMGC936, a first-in-class ADAM9-targeting antibody-drug conjugate, demonstrates promising anti-tumor activity

Stuart Hicks, Deryk Loo, Kerstin Sinkevicius, Juniper Scribner, Bhaswati Barat, Nicholas Yoder, Christopher Espelin, Marian Themeles, Francine Chen, Jacquelynn Lucas, Jennifer Brown, Bahar Matin, Megan Fuller, Jenny Lee, Paulin Salomon, Juliet Costoplus, Sadiqa Yancey, Gundo Diedrich, Sergey Gorlatov, Thomas Son, Michael Chiechi, Pam Li, Michael Spliedt, Valentina Ciccarone, Jeff Hooley, Nadia Gantt, James Tamura, Kerry Donahue, Paul Moore, Syd Johnson, Thomas Chittenden, Richard Gregory, Ezio Bonvini
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1533.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1533
Published: 01 July 2019
View article
Journal Articles

Abstract 1538: Margetuximab mediates greater Fc-dependent anti-tumor activities than trastuzumab or pertuzumab in vitro

Liqin Liu, Yinhua Yang, Robert Burns, Jonathan Li, Haiquan Li, Sergey Gorlatov, Paul Moore, Jeffrey Nordstrom
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1538.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1538
Published: 01 July 2019
View article
Journal Articles

Abstract 554: Tumor-antigen 5T4-dependent activation of the CD137 costimulatory pathway by bispecific 5T4 x CD137 x CD137 TRIDENT™ molecules

Liqin Liu, Ling Huang, Vatana Long, Yinhua Yang, Robert Burns, Jonathan Li, Jennifer DiChiara, Qihong Xu, Arin Whiddon, Chia-Ying K Lam, Jim Tamura, Valentina Ciccarone, Syd Johnson, Ezio Bonvini, Paul Moore
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 554.
DOI: https://doi.org/10.1158/1538-7445.AM2019-554
Published: 01 July 2019
View article
Journal Articles

Abstract 3642: Tumor-antigen expression-dependent activation of the CD137 costimulatory pathway by bispecific DART® proteins

Liqin Liu, Chia-Ying K. Lam, Vatana Long, Lusiana Widjaja, Yinhua Yang, Kalpana Shah, Doug Smith, Joanna Pan, Syd Johnson, Ezio Bonvini, Paul Moore
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3642.
DOI: https://doi.org/10.1158/1538-7445.AM2017-3642
Published: 01 July 2017
View article
Journal Articles

Abstract 4608: A 5T4 x CD3 bispecific DART® molecule with extended half-life for T-cell immunotherapy of cancers

Ling Huang, Gurunadh Chichili, Ralph Alderson, Francine Chen, Jennifer Brown, Hua Li, Valentina Ciccarone, Jim Tamura, Daorong Liu, Liqin Liu, Syd Johnson, Ezio Bonvini, Paul Moore
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4608.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4608
Published: 01 July 2017
View article
Journal Articles

Abstract 1489: Development of a humanized ROR1 x CD3 bispecific DART® molecule for the treatment of solid and liquid tumors

Bhaswati Barat, Gurunadh Chichili, Valentina Ciccarone, James Tamura, Sergey Gorlatov, Michael Spliedt, Francine Chen, Scott Koenig, Paul Moore, Ezio Bonvini, Ralph Alderson, Syd Johnson
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1489.
DOI: https://doi.org/10.1158/1538-7445.AM2016-1489
Published: 15 July 2016
View article
Journal Articles

Abstract 1498: Development of an IL13Ralpha2 x CD3 bispecific DART® protein for redirected T-cell killing of solid tumors

Jill Rillema, Monica Licea, Shereen Saini-Lal, Doug Smith, Francine Chen, Annie Lam, Yinhua Yang, Liqin Liu, James Tamura, Ralph Alderson, Ezio Bonvini, Syd Johnson, Paul Moore
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1498.
DOI: https://doi.org/10.1158/1538-7445.AM2016-1498
Published: 15 July 2016
View article
Journal Articles

Abstract 3217: MGD013, a bispecific PD-1 x LAG-3 Dual-Affinity Re-Targeting (DART®) protein with T-cell immunomodulatory activity for cancer treatment

Ross LaMotte-Mohs, Kalpana Shah, Doug Smith, Sergey Gorlatov, Valentina Ciccarone, James Tamura, Hua Li, Jill Rillema, Monica Licea, Leilei He, Farha Vasanwala, Wei Chen, Xiao-Tao Yao, Francine Chen, Jennifer Brown, Jeffrey Nordstrom, Scott Koenig, Ezio Bonvini, Syd Johnson, Paul Moore
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3217.
DOI: https://doi.org/10.1158/1538-7445.AM2016-3217
Published: 15 July 2016
View article
Journal Articles

Abstract 583: Evaluation of EphA2 as a therapeutic target for redirected T-cell killing by DART® bispecific molecules

Claudia B. Fieger, Kalpana Shah, Gurunadh Chichili, Jonathan Li, Thomas Son, Jeffrey Hooley, Francine Chen, Sergey Gorlatov, Steve Burke, Valentina Ciccarone, Ralph Alderson, Deryk Loo, Syd Johnson, Ezio Bonvini, Paul Moore
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 583.
DOI: https://doi.org/10.1158/1538-7445.AM2016-583
Published: 15 July 2016
View article
Journal Articles

Abstract 2476: Bispecific redirected T-cell immunotherapy targeting P-cadherin expressing tumors

Timothy S. Fisher, Adam Root, Bryan Peano, Allison Rohner, Justin Lucas, Mark Elliott, Konstantinos Tsaparikos, Hui Wang, Jonathan Golas, Maria Gavriil, Susan Benard, Tao He, Tracey Clark, Nahor Haddish-Berhane, Ralph Alderson, Yinhua Yang, Syd Johnson, Paul Moore, Lioudmila Tchistiakova, Hans-Peter Gerber, Chad May
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2476.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2476
Published: 01 August 2015
View article
Journal Articles

Abstract 2725: Preclinical development of an Fc-enhanced anti-B7-H3 monoclonal antibody with potent anti-tumor activity

Deryk T. Loo, Ralph Alderson, Francine Chen, Ling Huang, Wenjun Zhang, Sergey Gorlatov, Steve Burke, Valentina Ciccarone, Hua Li, Yinhua Yang, Thomas Son, Yan Chen, Jonathan Li, Jill Rillema, Monica Licea, Tony Liang, Jennie P. Mather, Scott Koenig, Stanford J. Stewart, Syd Johnson, Ezio Bonvini, Paul Moore
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2725.
DOI: https://doi.org/10.1158/1538-7445.AM2012-2725
Published: 15 April 2012
View article
Journal Articles

Mass spectrometry-based identification and initial validation of protein biomarkers for detection of lung cancer

Charles Birse, Mehdi Mesri, Erin Brand, Leilei He, William FitzHugh, Tao He, Paul Moore, Steve Ruben, Marcia Lewis
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 948.
Published: 01 May 2008
View article
Journal Articles

Membrane proteomic analyses of ovarian cancer identifies the immune modulators CD70 and B7-H2 as candidate markers of cisplatin response

Sudeepta Aggarwal, Tao He, William Fitzhugh, Kim Rosenthal, Brian Field, Deborah Mesmer, Elizabeth Joseloff, Steven Ruben, Paul Moore
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2430.
Published: 01 May 2008
View article
Journal Articles

The use of mass spectrometry based proteomics to identify cell surface proteins applicable for monitoring drug resistance, response and therapeutic targeting

Elizabeth Joseloff, Kim Rosenthal, Chad Danis, Tao He, Jenny Heidbrink, William FitzHugh, Candy Lee, Karen Van Orden, Steve Ruben, Paul Moore
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 614.
Published: 01 May 2007
View article
Journal Articles

Lung cancer biomarkers identified through mass spectrometry-based proteomic discovery from tissue and cell lines

Charles Birse, Mehdi Mesri, Elizabeth Joseloff, Erin Brand, Tao He, Aiqun Li, Gordon Nicol, Kim Alving, David Parmelee, Ahn Nguyen, Linda Wang, Karen Van Orden, David Tanenbaum, Marcia Lewis, Paul Moore, Steve Ruben
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 617.
Published: 01 May 2007
View article
Journal Articles

Proteomic analysis of colorectal tumor cells identifies CD133/Prominin-1, a cancer stem cell marker, as a monoclonal antibody therapeutic candidate

Karen Van Orden, Charles Birse, Tao He, Leia Smith, Katherine McKinnon, Candy Lee, William FitzHugh, Steven Duniho, Albina Nesterova, Ian McCaffery, Yeoun Jin Kim, Sudeepta Aggarwal, Deborah Mesmer, Paul Carter, Paul Moore, Steven Ruben
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1324.
Published: 01 May 2007
View article
Journal Articles

CD133/prominin-1 is a novel antibody therapeutic target in pancreatic, gastric and hepatocellular cancers

Leia Smith, Albina Nesterova, Maureen Ryan, Steven Duniho, Mechthild Jonas, Martha Anderson, Roger Zabinski, Karen Van Orden, Paul Moore, Steven Ruben, Paul Carter
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1332.
Published: 01 May 2007
View article
Journal Articles

HGS-TR2J, an agonistic, TRAIL receptor 2 monoclonal antibody, actively and rapidly stimulates the TRAIL receptor pathway that leads to significant inhibition of tumor growth in human tumor cell lines in vitro and in vivo

Robin C. Humphreys, Lindsey Shepard, Carol Poortman, Kathy McCormick, Clint Lincoln, Wendy Halpern, Paul Moore, Jim Fikes, Vivian Albert
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1038.
Published: 01 May 2005
View article