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Paul M. Harari
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Journal Articles

Abstract B027: Spatial transcriptomic profiling of the head and neck cancer tumor microenvironment to guide design of microphysiological systems for reporting treatment response

Free
Rene Welch Schwartz, Adeel Ahmed, Rong Hu, Randall J Kimple, Paul M Harari, Irene M Ong, Sheena C Kerr
Journal: Cancer Research
Cancer Res (2025) 85 (5_Supplement): B027.
https://doi.org/10.1158/1538-7445.GENFUNC25-B027
Published: 11 March 2025
View articletitled, Abstract B027: Spatial transcriptomic profiling of the head and neck cancer tumor microenvironment to guide design of microphysiological systems for reporting treatment response
Journal Articles

Abstract B023: Patient-specific, organotypic head and neck cancer model for personalized medicine

Free
Adeel Ahmed, Nathan W Hendrikse, Marcos A Lares, Fauzan Ahmed, Adam R Burr, Paul M Harari, David J Beebe, Sheena C Kerr
Journal: Cancer Research
Cancer Res (2025) 85 (5_Supplement): B023.
https://doi.org/10.1158/1538-7445.GENFUNC25-B023
Published: 11 March 2025
View articletitled, Abstract B023: Patient-specific, organotypic head and neck cancer model for personalized medicine
Journal Articles

Abstract B034: Engineering the tumor microenvironment: Patient-specific microphysiological systems of the head and neck cancer tumor microenvironment

Free
Adeel Ahmed, Marcos Lares, Fauzan Ahmed, Adam R. Burr, Paul M. Harari, David J. Beebe, Sheena C. Kerr
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): B034.
https://doi.org/10.1158/1538-7445.TUMBODY-B034
Published: 17 November 2024
View articletitled, Abstract B034: Engineering the tumor microenvironment: Patient-specific microphysiological systems of the head and neck cancer tumor microenvironment
Journal Articles

Abstract 3535: Simultaneous inhibition of Axl and MerTK enhances anti-PDL1 efficacy and creates a pro-inflammatory tumor immune microenvironment in head and neck cancer

Free
Kourtney L. Kostecki, Mari Iida, Anne L. Wiley, Seungpyo Hong, Ravi Salgia, Paul M. Harari, Deric L. Wheeler
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3535.
https://doi.org/10.1158/1538-7445.AM2022-3535
Published: 15 June 2022
View articletitled, Abstract 3535: Simultaneous inhibition of Axl and MerTK enhances anti-PDL1 efficacy and creates a pro-inflammatory tumor immune microenvironment in head and neck cancer
Journal Articles

Abstract 2929: Radiosensitization of head and neck cancer by FGFR inhibition

Free
Gopika SenthilKumar, Margot Miller, Michael Fisher, Sean Brennan, Saakshi Kaushik, Lindsey Able, Paul M. Harari, Gopal Iyer, Randall J. Kimple, Andrew M. Baschnagel
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2929.
https://doi.org/10.1158/1538-7445.AM2019-2929
Published: 01 July 2019
View articletitled, Abstract 2929: Radiosensitization of head and neck cancer by FGFR inhibition
Journal Articles

Abstract 851: Therapeutic combination of radiolabeled CLR1404 with external beam radiation in head and neck cancer murine xenograft models

Free
Chunrong Li, Jenna M. Mylin, Jamey P. Weichert, Justin J. Jeffery, Ashley M. Weichmann, Kwang P. Nickel, Lindsey J. Abel, Reinier Hernandez, Joseph J. Grudzinski, Ian R. Marsh, Bryan P. Bednarz, Shari M. Piaskowski, Paul M. Harari
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 851.
https://doi.org/10.1158/1538-7445.AM2018-851
Published: 01 July 2018
View articletitled, Abstract 851: Therapeutic combination of radiolabeled CLR1404 with external beam radiation in head and neck cancer murine xenograft models
Journal Articles

Abstract 1094: Combining the pan-FGFR inhibitor AZD4547 with radiation in lung and head and neck squamous cell carcinoma

Free
Andrew M. Baschnagel, Chunrong Li, Alecia M. Morgan, Sean R. Brennan, Kalley A. Russo, Paul M. Harari
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1094.
https://doi.org/10.1158/1538-7445.AM2017-1094
Published: 01 July 2017
View articletitled, Abstract 1094: Combining the pan-FGFR inhibitor AZD4547 with radiation in lung and head and neck squamous cell carcinoma
Journal Articles

Abstract 827: Statistical analyses of stable housekeeping gene expression in cancer post-irradiation

Free
Albert R. Wang, Gopal Iyer, Sean Brennan, Shay Bourgeois, Eric Armstrong, Pari Shah, Paul M. Harari
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 827.
https://doi.org/10.1158/1538-7445.AM2017-827
Published: 01 July 2017
View articletitled, Abstract 827: Statistical analyses of stable housekeeping gene expression in cancer post-irradiation
Journal Articles

Abstract 3044: Patient-derived adenoid cystic carcinoma xenografts to study molecular target modulation of tumor radiosensitivity

Free
Prashanth Prabakaran, Kwangok P. Nickel, David T. Yang, Lauryn R. Werner, Justine Y. Bruce, Aaron M. Wieland, Timothy M. McCulloch, Gregory K. Hartig, Paul M. Harari, Adam D. Swick, Randall J. Kimple
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3044.
https://doi.org/10.1158/1538-7445.AM2016-3044
Published: 15 July 2016
View articletitled, Abstract 3044: Patient-derived adenoid cystic carcinoma xenografts to study molecular target modulation of tumor radiosensitivity
Journal Articles

Abstract 2102A: Simultaneous targeting of EGFR and ALK in EML4-ALK positive lung cancer to inhibit tumor cell proliferation and migration

Free
Chunrong Li, Joseph G. Kern, Shyhmin Huang, Eric A. Armstrong, Lauryn R. Werner, Paul M. Harari
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2102A.
https://doi.org/10.1158/1538-7445.AM2016-2102A
Published: 15 July 2016
View articletitled, Abstract 2102A: Simultaneous targeting of EGFR and ALK in EML4-ALK positive lung cancer to inhibit tumor cell proliferation and migration
Journal Articles

Abstract 4013: Transcriptionally mediated effects of radiation on the expression of immune susceptibility markers in murine and human melanoma

Free
Lauryn R. Werner, Monica Gressett, Maureen Riegert, Shyhmin Huang, Joseph G. Kern, Amy Erbe, Paul M. Harari, Paul M. Sondel, Zachary S. Morris
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4013.
https://doi.org/10.1158/1538-7445.AM2016-4013
Published: 15 July 2016
View articletitled, Abstract 4013: Transcriptionally mediated effects of radiation on the expression of immune susceptibility markers in murine and human melanoma
Journal Articles

Abstract 4011: Effective in situ immunization via local radiation therapy (RT) and tumor-specific immunocytokine (IC): Suppression from distant tumor is blocked by RT or Treg-depleting CTLA-4 antibody

Free
Zachary S. Morris, Emily Guy, David Francis, Monica M. Gressett, Eric A. Armstrong, Shyhmin Huang, Lauryn R. Werner, Stephen D. Gillies, Alan Korman, Jacquelyn A. Hank, Alexander L. Rakhmilevich, Paul M. Harari, Paul M. Sondel
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4011.
https://doi.org/10.1158/1538-7445.AM2016-4011
Published: 15 July 2016
View articletitled, Abstract 4011: Effective in situ immunization via local radiation therapy (RT) and tumor-specific immunocytokine (IC): Suppression from distant tumor is blocked by RT or Treg-depleting CTLA-4 antibody
Journal Articles

In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments

Free
Zachary S. Morris, Emily I. Guy, David M. Francis, Monica M. Gressett, Lauryn R. Werner, Lakeesha L. Carmichael, Richard K. Yang, Eric A. Armstrong, Shyhmin Huang, Fariba Navid, Stephen D. Gillies, Alan Korman, Jacquelyn A. Hank, Alexander L. Rakhmilevich, Paul M. Harari, Paul M. Sondel
Journal: Cancer Research
Cancer Res (2016) 76 (13): 3929–3941.
https://doi.org/10.1158/0008-5472.CAN-15-2644
Published: 30 June 2016
View articletitled, In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments
Open the PDF for In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments in another window
Includes: Supplementary data
Journal Articles

Abstract 2630: Inhibition of angiogenesis contributes to enhanced radiation response in tumors following MDM2 inhibition by AMG 232

Free
Lauryn R. Werner, Shyhmin Huang, Eric A. Armstrong, Fang Ma, Jude Canon, Paul M. Harari
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2630.
https://doi.org/10.1158/1538-7445.AM2015-2630
Published: 01 August 2015
View articletitled, Abstract 2630: Inhibition of angiogenesis contributes to enhanced radiation response in tumors following MDM2 inhibition by AMG 232
Journal Articles

Abstract 3309: Co-inhibition of ALK and EGFR and/or c-MET on cell growth and response to radiation in ALK-positive NSCLC cells

Free
Chunrong Li, Shyhmin Huang, Fang Ma, Eric A. Armstrong, David Francis, Lauryn Werner, Paul M. Harari
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3309.
https://doi.org/10.1158/1538-7445.AM2015-3309
Published: 01 August 2015
View articletitled, Abstract 3309: Co-inhibition of ALK and EGFR and/or c-MET on cell growth and response to radiation in ALK-positive NSCLC cells
Journal Articles

Abstract 856: Combination of crizotinib and radiation in the treatment of ALK-positive and cetuximab-resistant lung cancer

Free
Chunrong Li, Shyhmin Huang, Noah Walters, Eric A. Armstrong, Paul M. Harari
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 856.
https://doi.org/10.1158/1538-7445.AM2014-856
Published: 01 October 2014
View articletitled, Abstract 856: Combination of crizotinib and radiation in the treatment of ALK-positive and cetuximab-resistant lung cancer
Journal Articles

Abstract 4495: Sym013, novel pan-HER monoclonal antibody mixture, augments radiation response in human lung and head and neck tumors

Free
David Francis, Shyhmin Huang, Lauryn Werner, Johan Lantto, Ivan D. Horak, Michael Kragh, Paul M. Harari
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4495.
https://doi.org/10.1158/1538-7445.AM2014-4495
Published: 01 October 2014
View articletitled, Abstract 4495: Sym013, novel pan-HER monoclonal antibody mixture, augments radiation response in human lung and head and neck tumors
Journal Articles

Abstract 2610: AMG 232, a small molecular inhibitor of MDM2 augments radiation response in human tumors harboring wild-type p53

Free
Lauryn Werner, Shyhmin Huang, Eric A. Armstrong, Dave Francis, Tao Osgood, Jude Canon, Paul M. Harari
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2610.
https://doi.org/10.1158/1538-7445.AM2014-2610
Published: 01 October 2014
View articletitled, Abstract 2610: AMG 232, a small molecular inhibitor of MDM2 augments radiation response in human tumors harboring wild-type p53
Journal Articles

Enhanced Radiation Sensitivity in HPV-Positive Head and Neck Cancer

Free
Randall J. Kimple, Molly A. Smith, Grace C. Blitzer, Alexandra D. Torres, Joshua A. Martin, Robert Z. Yang, Chimera R. Peet, Laurel D. Lorenz, Kwangok P. Nickel, Aloysius J. Klingelhutz, Paul F. Lambert, Paul M. Harari
Journal: Cancer Research
Cancer Res (2013) 73 (15): 4791–4800.
https://doi.org/10.1158/0008-5472.CAN-13-0587
Published: 31 July 2013
View articletitled, Enhanced Radiation Sensitivity in HPV-Positive Head and Neck Cancer
Open the PDF for Enhanced Radiation Sensitivity in HPV-Positive Head and Neck Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 73: Preclinical evaluation of chemoradiation with cetuximab HPV-positive head and neck cancer suggests significant radiosensitization.

Free
Molly A. Smith, Grace C. Blitzer, Alexandra D. Torres, Eric A. Armstrong, Paul F. Lambert, Paul M. Harari, Randall J. Kimple
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 73.
https://doi.org/10.1158/1538-7445.AM2013-73
Published: 15 April 2013
View articletitled, Abstract 73: Preclinical evaluation of chemoradiation with cetuximab HPV-positive head and neck cancer suggests significant radiosensitization.