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Abstract 4807: Braf mutations initiate the development of rat gliomas induced by postnatal exposure to N-ethyl-N-nitrosourea (ENU)

Kaishi Satomi, Qi Wang, Ji Eun Oh, Barbara Hutter, Benedikt Brors, Nicolle Diessl, Hai-Kun Liu, Stephan Wolf, Otmar Wiestler, Paul Kleihues, Bernd Koelsch, Andrea Kindler-Rohrborn, Hiroko Ohgaki

Cancer Res (2017) 77 (13_Supplement): 4807.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4807

Published: 01 July 2017

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Journal Articles

Genetic Pathways to Glioblastoma: A Population-Based Study

Hiroko Ohgaki, Pierre Dessen, Benjamin Jourde, Sonja Horstmann, Tomofumi Nishikawa, Pier-Luigi Di Patre, Christoph Burkhard, Danielle Schüler, Nicole M. Probst-Hensch, Paulo César Maiorka, Nathalie Baeza, Paola Pisani, Yasuhiro Yonekawa, M. Gazi Yasargil, Urs M. Lütolf, Paul Kleihues

Cancer Res (2004) 64 (19): 6892–6899.

DOI: https://doi.org/10.1158/0008-5472.CAN-04-1337

Published: 01 October 2004

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Journal Articles

Li-Fraumeni and Related Syndromes: Correlation between Tumor Type, Family Structure, and TP53 Genotype

Magali Olivier, David E. Goldgar, Nayanta Sodha, Hiroko Ohgaki, Paul Kleihues, Pierre Hainaut, Rosalind A. Eeles

Cancer Res (2003) 63 (20): 6643–6650.

Published: 28 October 2003

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Journal Articles

Soluble Decoy Receptor 3 Is Expressed by Malignant Gliomas and Suppresses CD95 Ligand-induced Apoptosis and Chemotaxis

Wilfried Roth, Stefan Isenmann, Mitsutoshi Nakamura, Michael Platten, Wolfgang Wick, Paul Kleihues, Mathias Bähr, Hiroko Ohgaki, Avi Ashkenazi, Michael Weller

Cancer Res (2001) 61 (6): 2759–2765.

Published: 01 March 2001

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Journal Articles

Gene Expression Profiling of Low-Grade Diffuse Astrocytomas by cDNA Arrays

Huatao Huang, Stefano Colella, Michael Kurrer, Yasuhiro Yonekawa, Paul Kleihues, Hiroko Ohgaki

Cancer Res (2000) 60 (24): 6868–6874.

Published: 01 December 2000

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Journal Articles

Loss of DCC Expression and Glioma Progression

Miguel Reyes-Mugica, Kimberly Rieger-Christ, Hiroko Ohgaki, Bradley C. Ekstrand, Mary Helie, George Kleinman, Alan Yahanda, Eric R. Fearon, Paul Kleihues, Michael A. Reale

Cancer Res (1997) 57 (3): 382–386.

Published: 01 February 1997

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Journal Articles

Expression of Fas/APO-1 during the Progression of Astrocytomas

Osamu Tachibana, Hisayoshi Nakazawa, Johannes Lampe, Kunihiko Watanabe, Paul Kleihues, Hiroko Ohgaki

Cancer Res (1995) 55 (23): 5528–5530.

Published: 01 December 1995

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Journal Articles

Oncogene Complementation in Fetal Brain Transplants

Otmar D. Wiestler, Adriano Aguzzi, Markus Schneemann, Robert Eibl, Andreas von Deimling, Paul Kleihues

Cancer Res (1992) 52 (13): 3760–3767.

Published: 01 July 1992

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Journal Articles

p53 Mutations Are Associated with 17p Allelic Loss in Grade II and Grade III Astrocytoma

Andreas von Deimling, Robert H. Eibl, Hiroko Ohgaki, David N. Louis, Klaus von Ammon, Iver Petersen, Paul Kleihues, Richard Y. Chung, Otmar D. Wiestler, Bernd R. Seizinger

Cancer Res (1992) 52 (10): 2987–2990.

Published: 01 May 1992

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Journal Articles

Selective Mutation of Codons 204 and 213 of the p53 Gene in Rat Tumors Induced by Alkylating N-Nitroso Compounds

Hiroko Ohgaki, Gordon C. Hard, Norio Hirota, Akihiko Maekawa, Michihito Takahashi, Paul Kleihues

Cancer Res (1992) 52 (10): 2995–2998.

Published: 01 May 1992

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Journal Articles

p53 Mutations in Nonastrocytic Human Brain Tumors

Hiroko Ohgaki, Robert H. Eibl, Otmar D. Wiestler, M. Gazi Yasargil, Elizabeth W. Newcomb, Paul Kleihues

Cancer Res (1991) 51 (22): 6202–6205.

Published: 01 November 1991

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Journal Articles

Organ and Cell Specificity of DNA Methylation by N-Nitrosomethylamylamine in Rats

Michael Koenigsmann, Ivo Schmerold, Willy Jeltsch, Barbara Ludeke, Paul Kleihues, Manfred Wiessler

Cancer Res (1988) 48 (19): 5482–5486.

Published: 01 October 1988

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Journal Articles

Differential Proliferative Response of Gastric Mucosa during Carcinogenesis Induced by N-Methyl-N′-nitro-N-nitrosoguanidine in Susceptible ACI Rats, Resistant Buffalo Rats, and Their Hybrid F₁ Cross

Hiroko Ohgaki, Miki Tomihari, Shigeaki Sato, Paul Kleihues, Takashi Sugimura

Cancer Res (1988) 48 (18): 5275–5279.

Published: 01 September 1988

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Journal Articles

Selective Induction by N-Nitrosoethylurea of Oligodendrogliomas in Fetal Forebrain Transplants

Peter C. Burger, Taichiro Shibata, Adriano Aguzzi, Paul Kleihues

Cancer Res (1988) 48 (10): 2871–2875.

Published: 01 May 1988

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Journal Articles

Methylation versus Ethylation of DNA in Target and Nontarget Tissues of Fischer 344 Rats Treated with N-Nitrosomethylethylamine

Eric von Hofe, Friedrich Grahmann, Larry K. Keefer, William Lijinsky, Victor Nelson, Paul Kleihues

Cancer Res (1986) 46 (3): 1038–1042.

Published: 01 March 1986

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Journal Articles

DNA Methylation by Dimethylnitrosamine in the Mongolian Gerbil (Meriones unguiculatus): Indications of a Deficient, Noninducible Hepatic Repair System for O⁶-Methylguanine

Stephan Bamborschke, Peter J. O'Connor, Geoffrey P. Margison, Paul Kleihues, Girish B. Maru

Cancer Res (1983) 43 (3): 1306–1311.

Published: 01 March 1983

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Journal Articles

Mechanism of Esophageal Tumor Induction in Rats by N-Nitrosomethylbenzylamine and Its Ring-methylated Analog N-Nitrosomethyl(4-methylbenzyl)amine

Ruth M. Hodgson, Fritz Schweinsberg, Manfred Wiessler, Paul Kleihues

Cancer Res (1982) 42 (7): 2836–2840.

Published: 01 July 1982

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Journal Articles

Correlation of DNA Methylation by Methyl(acetoxymethyl)nitrosamine with Organ-specific Carcinogenicity in Rats

Paul Kleihues, Gerhard Doerjer, Larry K. Keefer, Jerry M. Rice, Peter P. Roller, Ruth M. Hodgson

Cancer Res (1979) 39 (12): 5136–5140.

Published: 01 December 1979

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Journal Articles

DNA Alkylation in Mice with Genetically Different Susceptibility to 1,2-Dimethylhydrazine-induced Colon Carcinogenesis

Helen K. Cooper, Joachim Buecheler, Paul Kleihues

Cancer Res (1978) 38 (9): 3063–3065.

Published: 01 September 1978

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Journal Articles

Interaction of the Carcinogen 3,3-Dimethyl-1-phenyltriazene with Nucleic Acids of Various Rat Tissues and the Effect of a Protein-free Diet

Paul Kleihues, George F. Kolar, Geoffrey P. Margison

Cancer Res (1976) 36 (7_Part_1): 2189–2193.

Published: 01 July 1976

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NARROW

Abstract 4807: Braf mutations initiate the development of rat gliomas induced by postnatal exposure to N-ethyl-N-nitrosourea (ENU)

Genetic Pathways to Glioblastoma: A Population-Based Study

Li-Fraumeni and Related Syndromes: Correlation between Tumor Type, Family Structure, and TP53 Genotype

Soluble Decoy Receptor 3 Is Expressed by Malignant Gliomas and Suppresses CD95 Ligand-induced Apoptosis and Chemotaxis

Gene Expression Profiling of Low-Grade Diffuse Astrocytomas by cDNA Arrays

Loss of DCC Expression and Glioma Progression

Expression of Fas/APO-1 during the Progression of Astrocytomas

Oncogene Complementation in Fetal Brain Transplants

p53 Mutations Are Associated with 17p Allelic Loss in Grade II and Grade III Astrocytoma

Selective Mutation of Codons 204 and 213 of the p53 Gene in Rat Tumors Induced by Alkylating N-Nitroso Compounds

p53 Mutations in Nonastrocytic Human Brain Tumors

Organ and Cell Specificity of DNA Methylation by N-Nitrosomethylamylamine in Rats

Differential Proliferative Response of Gastric Mucosa during Carcinogenesis Induced by N-Methyl-N′-nitro-N-nitrosoguanidine in Susceptible ACI Rats, Resistant Buffalo Rats, and Their Hybrid F₁ Cross

Selective Induction by N-Nitrosoethylurea of Oligodendrogliomas in Fetal Forebrain Transplants

Methylation versus Ethylation of DNA in Target and Nontarget Tissues of Fischer 344 Rats Treated with N-Nitrosomethylethylamine

DNA Methylation by Dimethylnitrosamine in the Mongolian Gerbil (Meriones unguiculatus): Indications of a Deficient, Noninducible Hepatic Repair System for O⁶-Methylguanine

Mechanism of Esophageal Tumor Induction in Rats by N-Nitrosomethylbenzylamine and Its Ring-methylated Analog N-Nitrosomethyl(4-methylbenzyl)amine

Correlation of DNA Methylation by Methyl(acetoxymethyl)nitrosamine with Organ-specific Carcinogenicity in Rats

DNA Alkylation in Mice with Genetically Different Susceptibility to 1,2-Dimethylhydrazine-induced Colon Carcinogenesis

Interaction of the Carcinogen 3,3-Dimethyl-1-phenyltriazene with Nucleic Acids of Various Rat Tissues and the Effect of a Protein-free Diet

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