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Journal Articles

Abstract 1853: The Chk1 inhibitor, SRA737, synergizes with niraparib to kill cancer cells via multiple cell death pathways

Laurence Booth, Jane Roberts, Andrew Poklepovic, Ryan J. Hansen, Bryan Strouse, Snezana Milutinovic, Christian Hassig, Paul Dent

Cancer Res (2018) 78 (13_Supplement): 1853.

https://doi.org/10.1158/1538-7445.AM2018-1853

Published: 01 July 2018

View article titled, Abstract 1853: The Chk1 inhibitor, SRA737, synergizes with niraparib to kill cancer cells via multiple cell death pathways

Journal Articles

Abstract 1741: GRP78 / BiP / HSPA5 expression and those of other chaperone proteins is rapidly degraded by OSU-03012 and Viagra exposure: Implications for anti-cancer and anti-pathogen therapies

Laurence A. Booth, Jane L. Roberts, Paul Dent

Cancer Res (2015) 75 (15_Supplement): 1741.

https://doi.org/10.1158/1538-7445.AM2015-1741

Published: 01 August 2015

View article titled, Abstract 1741: GRP78 / BiP / HSPA5 expression and those of other chaperone proteins is rapidly degraded by OSU-03012 and Viagra exposure: Implications for anti-cancer and anti-pathogen therapies

Journal Articles

Abstract LB-094: Regorafenib and sildenafil interact to kill tumor cells

Mehrad Tavallai, Laurence Booth, Jane L. Roberts, Andrew Poklepovic, Paul Dent

Cancer Res (2015) 75 (15_Supplement): LB-094.

https://doi.org/10.1158/1538-7445.AM2015-LB-094

Published: 01 August 2015

View article titled, Abstract LB-094: Regorafenib and sildenafil interact to kill tumor cells

Journal Articles

Abstract 3503: Gilenya and Alimta interact to kill breast cancer cells

Jane L. Roberts, Seyedmehrad Tavallai, Andrew Poklepovic, Laurence Booth, Paul Dent

Cancer Res (2015) 75 (15_Supplement): 3503.

https://doi.org/10.1158/1538-7445.AM2015-3503

Published: 01 August 2015

View article titled, Abstract 3503: Gilenya and Alimta interact to kill breast cancer cells

Journal Articles

Abstract 796: Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ERBB2 therapy

Nichola A. Cruickshanks, Hossein A. Hamed, Larry A. Booth, Seyedmehrad Tavallai, G B. Sajithlal, Steven Grant, Andrew Poklepovic, Paul Dent

Cancer Res (2014) 74 (19_Supplement): 796.

https://doi.org/10.1158/1538-7445.AM2014-796

Published: 01 October 2014

View article titled, Abstract 796: Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ERBB2 therapy

Journal Articles

Abstract 2690: Sorafenib/regorafenib and phosphatidyl inositol 3 kinase/thymoma viral proto-oncogene inhibition interact to kill tumor cells

Larry A. Booth, Nichola A. Cruickshanks, G B. Sajithlal, Hossein A. Hamed, Seyedmehrad Tavallai, J Syed, Steven Grant, Andrew Poklepovic, Paul Dent

Cancer Res (2014) 74 (19_Supplement): 2690.

https://doi.org/10.1158/1538-7445.AM2014-2690

Published: 01 October 2014

View article titled, Abstract 2690: Sorafenib/regorafenib and phosphatidyl inositol 3 kinase/thymoma viral proto-oncogene inhibition interact to kill tumor cells

Journal Articles

Abstract B85: MDA-9/syntenin is a key regulator of glioma pathogenesis

Timothy P. Kegelman, Swadesh K. Das, Bin Hu, Mitchell Menezes, Luni Emdad, Santanu Dasgupta, Albert S. Baldwin, Jr., Jeffery N. Bruce, Paul Dent, Maurizio Pellecchia, Devanand Sarkar, Paul B. Fisher

Cancer Res (2013) 73 (3_Supplement): B85.

https://doi.org/10.1158/1538-7445.TIM2013-B85

Published: 01 May 2014

View article titled, Abstract B85: MDA-9/syntenin is a key regulator of glioma pathogenesis

Journal Articles

Abstract 2618: MDA-9/syntenin is a key regulator of glioma pathogenesis.

Timothy P. Kegelman, Swadesh K. Das, Bin Hu, Mitchell Menezes, Luni Emdad, Santanu Dasgupta, Albert S. Baldwin, Jeffrey N. Bruce, Paul Dent, Maurizio Pellecchia, Devanand Sarkar, Paul B. Fisher

Cancer Res (2013) 73 (8_Supplement): 2618.

https://doi.org/10.1158/1538-7445.AM2013-2618

Published: 15 April 2013

View article titled, Abstract 2618: MDA-9/syntenin is a key regulator of glioma pathogenesis.

Journal Articles

Abstract LB-315: Chemoprevention gene therapy (CGT) approach for pancreatic cancer.

Siddik Sarkar, Belal Azab, Bridget A. Quinn, Xuening Shen, Paul Dent, Alexander L. Klibanov, Luni Emdad, Swadesh K. Das, Devanand Sarkar, Paul B. Fisher

Cancer Res (2013) 73 (8_Supplement): LB-315.

https://doi.org/10.1158/1538-7445.AM2013-LB-315

Published: 15 April 2013

View article titled, Abstract LB-315: Chemoprevention gene therapy (CGT) approach for pancreatic cancer.

Journal Articles

Abstract 2628: The multifunctional protein staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion of hepatocellular carcinoma (HCC) cells by modulating angiotensin II type 1 receptor (AT1R) and transforming growth factor-β (TGF-β) s

Prasanna K. Santhekadur, Rachel Gredler, Maaged Akiel, Paul Dent, Paul B. Fisher, Devanand Sarkar

Cancer Res (2013) 73 (8_Supplement): 2628.

https://doi.org/10.1158/1538-7445.AM2013-2628

Published: 15 April 2013

View article titled, Abstract 2628: The multifunctional protein staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion of hepatocellular carcinoma (HCC) cells by modulating angiotensin II type 1 receptor (AT1R) and transforming growth factor-β (TGF-β) s

Journal Articles

Abstract 3902: MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma.

Swadesh K. Das, Timothy P. Kegelman, Prasanna K. Santhekadur, Santanu Dasgupta, Paul Dent, Steven Grant, Luni Emdad, Devanand Sarkar, Paul B. Fisher, Maurizio Pellecchia

Cancer Res (2013) 73 (8_Supplement): 3902.

https://doi.org/10.1158/1538-7445.AM2013-3902

Published: 15 April 2013

View article titled, Abstract 3902: MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma.

Journal Articles

MDA-9/Syntenin and IGFBP-2 Promote Angiogenesis in Human Melanoma

Swadesh K. Das, Sujit K. Bhutia, Belal Azab, Timothy P. Kegelman, Leyla Peachy, Prasanna K. Santhekadur, Santanu Dasgupta, Rupesh Dash, Paul Dent, Steven Grant, Luni Emdad, Maurizio Pellecchia, Devanand Sarkar, Paul B. Fisher

Cancer Res (2013) 73 (2): 844–854.

https://doi.org/10.1158/0008-5472.CAN-12-1681

Published: 16 January 2013

View article titled, MDA-9/Syntenin and IGFBP-2 Promote Angiogenesis in Human Melanoma

Includes: Supplementary data

Journal Articles

CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies

Shuang Chen, Yun Dai, Xin-Yan Pei, Jennifer Myers, Li Wang, Lora B. Kramer, Mandy Garnett, Daniella M. Schwartz, Florence Su, Gary L. Simmons, Justin D. Richey, Dustin G. Larsen, Paul Dent, Robert Z. Orlowski, Steven Grant

Cancer Res (2012) 72 (16): 4225–4237.

https://doi.org/10.1158/0008-5472.CAN-12-1118

Published: 14 August 2012

View article titled, CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies

Includes: Multimedia, Supplementary data

Journal Articles

Abstract 61: A new serotype chimera Cancer Terminator Virus (Ad.5/3-CTV) expands the efficiency and specificity of prostate cancer gene transfer and therapy

Belal Azab, Rupesh Dash, Swadesh Das, Sujit Bhutia, Xue-Ning Shen, Bridget Quinn, Santanu Dasgupta, Paul Dent, Igor Dmitriev, Xiang-Yang Wang, David Curiel, Steven Grant, Maurizio Pellecchia, John Reed, Devanand Sarkar, Paul Fisher

Cancer Res (2012) 72 (8_Supplement): 61.

https://doi.org/10.1158/1538-7445.AM2012-61

Published: 15 April 2012

View article titled, Abstract 61: A new serotype chimera Cancer Terminator Virus (Ad.5/3-CTV) expands the efficiency and specificity of prostate cancer gene transfer and therapy

Journal Articles

Sorafenib Enhances Pemetrexed Cytotoxicity through an Autophagy-Dependent Mechanism in Cancer Cells

M. Danielle Bareford, Margaret A. Park, Adly Yacoub, Hossein A. Hamed, Yong Tang, Nichola Cruickshanks, Patrick Eulitt, Nisan Hubbard, Gary Tye, Matthew E. Burow, Paul B. Fisher, Richard G. Moran, Kenneth P. Nephew, Steven Grant, Paul Dent

Cancer Res (2011) 71 (14): 4955–4967.

https://doi.org/10.1158/0008-5472.CAN-11-0898

Published: 14 July 2011

View article titled, Sorafenib Enhances Pemetrexed Cytotoxicity through an Autophagy-Dependent Mechanism in Cancer Cells

Includes: Supplementary data

Journal Articles

Abstract 5367: Simultaneous inhibition of Chk1 and MEK1/2 targets non-proliferating multiple myeloma cells

Xin-Yan Pei, Yun Dai, Leena E. Youssefian, Shuang Chen, Wesley Bodie, Yukie Takabatake, George Almenara, Lora Kramer, Paul Dent, Steven Grant

Cancer Res (2011) 71 (8_Supplement): 5367.

https://doi.org/10.1158/1538-7445.AM2011-5367

Published: 15 April 2011

View article titled, Abstract 5367: Simultaneous inhibition of Chk1 and MEK1/2 targets non-proliferating multiple myeloma cells

Journal Articles

Abstract 5366: The small molecule Bcl-2 antagonist obatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC and ABC- sub types of DLBCL cells both in vitro and in vivo

Girija P. Dasmahapatra, Dmitry Lembersky, Jonathan W. Friedberg, Richard I. Fisher, Paul Dent, Steven Grant

Cancer Res (2011) 71 (8_Supplement): 5366.

https://doi.org/10.1158/1538-7445.AM2011-5366

Published: 15 April 2011

View article titled, Abstract 5366: The small molecule Bcl-2 antagonist obatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC and ABC- sub types of DLBCL cells both in vitro and in vivo

Journal Articles

Abstract 5390: A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels

Mary Danielle Bareford, Hossein A. Hamed, Margaret Park, Steven Grant, Paul Fisher, Paul Dent

Cancer Res (2011) 71 (8_Supplement): 5390.

https://doi.org/10.1158/1538-7445.AM2011-5390

Published: 15 April 2011

View article titled, Abstract 5390: A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels

Journal Articles

Abstract 5383: Inhibition of MCL-1 in mammary and CNS tumor cells promotes cell death in vitro and in vivo

Hossein A. Hamed, Clint Mitchell, Paul Dent, Adly Yacoub, Gary Tye, Mary Danielle Bareford

Cancer Res (2011) 71 (8_Supplement): 5383.

https://doi.org/10.1158/1538-7445.AM2011-5383

Published: 15 April 2011

View article titled, Abstract 5383: Inhibition of MCL-1 in mammary and CNS tumor cells promotes cell death in vitro and in vivo

Journal Articles

Cytokine Receptor CXCR4 Mediates Estrogen-Independent Tumorigenesis, Metastasis, and Resistance to Endocrine Therapy in Human Breast Cancer

Cancer Res (2011) 71 (2): 603–613.

https://doi.org/10.1158/0008-5472.CAN-10-3185

Published: 13 January 2011

View article titled, Cytokine Receptor CXCR4 Mediates Estrogen-Independent Tumorigenesis, Metastasis, and Resistance to Endocrine Therapy in Human Breast Cancer

Includes: Supplementary data

NARROW

Abstract 1853: The Chk1 inhibitor, SRA737, synergizes with niraparib to kill cancer cells via multiple cell death pathways

Abstract 1741: GRP78 / BiP / HSPA5 expression and those of other chaperone proteins is rapidly degraded by OSU-03012 and Viagra exposure: Implications for anti-cancer and anti-pathogen therapies

Abstract LB-094: Regorafenib and sildenafil interact to kill tumor cells

Abstract 3503: Gilenya and Alimta interact to kill breast cancer cells

Abstract 796: Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ERBB2 therapy

Abstract 2690: Sorafenib/regorafenib and phosphatidyl inositol 3 kinase/thymoma viral proto-oncogene inhibition interact to kill tumor cells

Abstract B85: MDA-9/syntenin is a key regulator of glioma pathogenesis

Abstract 2618: MDA-9/syntenin is a key regulator of glioma pathogenesis.

Abstract LB-315: Chemoprevention gene therapy (CGT) approach for pancreatic cancer.

Abstract 2628: The multifunctional protein staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion of hepatocellular carcinoma (HCC) cells by modulating angiotensin II type 1 receptor (AT1R) and transforming growth factor-β (TGF-β) s

Abstract 3902: MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma.

MDA-9/Syntenin and IGFBP-2 Promote Angiogenesis in Human Melanoma

CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies

Abstract 61: A new serotype chimera Cancer Terminator Virus (Ad.5/3-CTV) expands the efficiency and specificity of prostate cancer gene transfer and therapy

Sorafenib Enhances Pemetrexed Cytotoxicity through an Autophagy-Dependent Mechanism in Cancer Cells

Abstract 5367: Simultaneous inhibition of Chk1 and MEK1/2 targets non-proliferating multiple myeloma cells

Abstract 5366: The small molecule Bcl-2 antagonist obatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC and ABC- sub types of DLBCL cells both in vitro and in vivo

Abstract 5390: A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels

Abstract 5383: Inhibition of MCL-1 in mammary and CNS tumor cells promotes cell death in vitro and in vivo

Cytokine Receptor CXCR4 Mediates Estrogen-Independent Tumorigenesis, Metastasis, and Resistance to Endocrine Therapy in Human Breast Cancer

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