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Journal Articles

Abstract IA10: Targeting melanoma metabolism to overcome resistance to treatment

Allison Betoff, Jonathan Zippin, Taha Merghoub, Paul B. Chapman, Jedd Wolchok
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): IA10.
DOI: https://doi.org/10.1158/1538-7445.MEL2019-IA10
Published: 02 October 2020
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Journal Articles

Abstract LB-227: Estimation of tumor-derived mutant allele fractions in cfDNA by shallow whole genome sequencing and fragment size analysis

Julie Yang, Francesco Marass, Peter Ulz, Maha Shady, Michael L. Cheng, Prachi Kothari, Erika Gedvilaite, Saira Somnay, Neerav Shukla, Shakeel Modak, Emily K. Slotkin, Dana E. Rathkopf, Iyer Gopaumar, Howard I. Scher, Pedram Razavi, Darren R. Feldman, Bob T. Li, Paul B. Chapman, Jonathan E. Rosenberg, Dean F. Bajorin, Howard I. Scher, Michael F. Berger, Venkatraman E. Seshan, Nicholas D. Socci, David B. Solit, Ellen Heitzer, Dana W. Y. Tsui
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-227.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-227
Published: 01 July 2018
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Journal Articles

Loss of NF1 in Cutaneous Melanoma Is Associated with RAS Activation and MEK Dependence

Moriah H. Nissan, Christine A. Pratilas, Alexis M. Jones, Ricardo Ramirez, Helen Won, Cailian Liu, Shakuntala Tiwari, Li Kong, Aphrothiti J. Hanrahan, Zhan Yao, Taha Merghoub, Antoni Ribas, Paul B. Chapman, Rona Yaeger, Barry S. Taylor, Nikolaus Schultz, Michael F. Berger, Neal Rosen, David B. Solit
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (8): 2340–2350.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-2625
Published: 15 April 2014
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Includes: Supplementary data
Journal Articles

Abstract 2284: Phase II trial of MEK inhibitor selumetinib (AZD6244) in patients with BRAFV600E/K- or NRAS-mutated melanoma.

Federica Catalanotti, David B. Solit, Melissa P. Pulitzer, Michael F. Berger, Sasinya N. Scott, Tunc Iyriboz, Mario E. Lacouture, Katherine S. Panageas, Jedd D. Wolchok, Richard D. Carvajal, Gary K. Schwartz, Neal Rosen, Paul B. Chapman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2284.
DOI: https://doi.org/10.1158/1538-7445.AM2013-2284
Published: 15 April 2013
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Journal Articles

Abstract LB-428: RAS-independent dimerization of BRAF(V600E) splicing variants promotes resistance to RAF inhibitors

Poulikos I. Poulikakos, Yogindra Persaud, Manickam Janakiraman, Xiangju Kong, Charles Ng, Gatien Moriceau, Hubing Shi, Mohammad Atefi, Bjoern Titz, May Tal Gabay, Maayan Salton, Kimberly B. Dahlman, Madhavi Tadi, Jennifer A. Wargo, Keith T. Flaherty, Mark C. Kelley, Tom Misteli, Paul B. Chapman, Jeffrey A. Sosman, Thomas G. Graeber, Antoni Ribas, Roger S. Lo, Neal Rosen, David B. Solit
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-428.
DOI: https://doi.org/10.1158/1538-7445.AM2012-LB-428
Published: 15 April 2012
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Journal Articles

Abstract LB-419: An in-frame deletion in the N-terminal regulatory domain of BRAF(V600E) causes resistance to the RAF inhibitor PLX4032

Poulikos I. Poulikakos, Yogindra Persaud, May Tal Gabay, Manickam Janakiraman, Eric W. Joseph, Christine A. Pratilas, Paul B. Chapman, Neal Rosen, David B. Solit
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-419.
DOI: https://doi.org/10.1158/1538-7445.AM2011-LB-419
Published: 15 April 2011
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Journal Articles

Treatment of melanoma patients with 17AAG results in downregulation of the MAPK pathway in the melanoma tumors

Philip Friedlander, David Solit, Iman Osman, David Polsky, Ronald Elamparo, Neal Rosen, Paul B. Chapman
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 352.
Published: 01 May 2005
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Journal Articles

Clinical significance of BRAF or NRAS mutations in metastatic melanoma.

David Z. Chang, Katherine S. Panageas, Iman Osman, David Polsky, David Polsky, Paul B. Chapman
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 846.
Published: 01 April 2004
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Journal Articles

Phase I Evaluation of a Combination of Monoclonal Antibody R24 and Interleukin 2 in Patients with Metastatic Melanoma

Dean F. Bajorin, Paul B. Chapman, George Wong, Daniel G. Coit, Jolanta Kunicka, Joseph Dimaggio, Carlos Cordon-Cardo, Carlos Urmacher, Lucy Dantes, Mary Agnes Templeton, John Liu, Herbert F. Oettgen, Alan N. Houghton
Journal: Cancer Research
Cancer Res (1990) 50 (23): 7490–7495.
Published: 01 December 1990
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Journal Articles

Light Chain Variants of an IgG3 Anti-GD3 Monoclonal Antibody and the Relationship among Avidity, Effector Functions, Tumor Targeting, and Antitumor Activity

Paul B. Chapman, Mathew Lonberg, Alan N. Houghton
Journal: Cancer Research
Cancer Res (1990) 50 (5): 1503–1509.
Published: 01 March 1990
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