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Patrick Turko
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Journal Articles

Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma

Lorenza P. Ferretti, Flurina Böhi, Deena M. Leslie Pedrioli, Phil F. Cheng, Elena Ferrari, Petra Baumgaertner, Abdiel Alvarado-Diaz, Federica Sella, Alessandra Cereghetti, Patrick Turko, Roni H. Wright, Katrien De Bock, Daniel E. Speiser, Roberto Ferrari, Mitchell P. Levesque, Michael O. Hottiger
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3974–3988.
https://doi.org/10.1158/0008-5472.CAN-23-0485
Published: 01 December 2023
View article titled, Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma
Open the PDF for Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma in another window
Includes: Supplementary data
Journal Articles

ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma

Ossia M. Eichhoff, Corinne I. Stoffel, Jan Käsler, Luzia Briker, Patrick Turko, Gergely Karsai, Nina Zila, Verena Paulitschke, Phil F. Cheng, Alexander Leitner, Andrea Bileck, Nicola Zamboni, Anja Irmisch, Zsolt Balazs, Aizhan Tastanova, Susana Pascoal, Pål Johansen, Rebekka Wegmann, Julien Mena, Alaa Othman, Vasanthi S. Viswanathan, Judith Wenzina, Andrea Aloia, Annalisa Saltari, Andreas Dzung, TuPro Consortium, Michael Krauthammer, Stuart L. Schreiber, Thorsten Hornemann, Martin Distel, Berend Snijder, Reinhard Dummer, Mitchell P. Levesque
Journal: Cancer Research
Cancer Res (2023) 83 (7): 1128–1146.
https://doi.org/10.1158/0008-5472.CAN-22-1826
Published: 04 April 2023
View article titled, ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma
Open the PDF for ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma in another window
Includes: Supplementary data
Journal Articles

Specific Activation of the CD271 Intracellular Domain in Combination with Chemotherapy or Targeted Therapy Inhibits Melanoma Progression

Annalisa Saltari, Andreas Dzung, Marika Quadri, Natascia Tiso, Nicola Facchinello, Alberto Hernández-Barranco, Susana Garcia-Silva, Laura Nogués, Corinne Isabelle Stoffel, Phil F. Cheng, Patrick Turko, Ossia M. Eichhoff, Francesca Truzzi, Alessandra Marconi, Carlo Pincelli, Héctor Peinado, Reinhard Dummer, Mitchell P. Levesque
Journal: Cancer Research
Cancer Res (2021) 81 (23): 6044–6057.
https://doi.org/10.1158/0008-5472.CAN-21-0117
Published: 01 December 2021
View article titled, Specific Activation of the CD271 Intracellular Domain in Combination with Chemotherapy or Targeted Therapy Inhibits Melanoma Progression
Open the PDF for Specific Activation of the CD271 Intracellular Domain in Combination with Chemotherapy or Targeted Therapy Inhibits Melanoma Progression in another window
Includes: Supplementary data