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Patricia J. Keller
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Journal Articles

Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of ARID1A Mutant Cancers

Patricia J. Keller, Elizabeth J. Adams, Rentian Wu, Alexandre Côté, Shilpi Arora, Nico Cantone, Rosana Meyer, Jennifer A. Mertz, Victor Gehling, Jike Cui, Jacob I. Stuckey, Avinash Khanna, Feng Zhao, Zehua Chen, Ziyang Yu, Richard T. Cummings, Mohammed Taimi, Nehal J. Lakhani, Drew Rasco, Martin Gutierrez, Linda Duska, Michael Devitt, Ronda Rippley, Julian Levell, Jennifer Truong, Jing Wang, Kaiming Sun, Patrick Trojer
Journal: Cancer Research
Cancer Res (2024) 84 (15): 2501–2517.
https://doi.org/10.1158/0008-5472.CAN-24-0398
Published: 01 August 2024
View article titled, Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of <em>ARID1A</em> Mutant Cancers
Open the PDF for Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of <em>ARID1A</em> Mutant Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 2126: Therapeutic potential of CPI-0209

Rentian Wu, Feng Zhao, Patricia J. Keller, Jennifer A. Mertz, John P. McGrath, Barbara Bryant, Andrew R. Conery, Kaiming Sun, Jing Wang, Patrick Trojer
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2126.
https://doi.org/10.1158/1538-7445.AM2021-2126
Published: 01 July 2021
View article titled, Abstract 2126: Therapeutic potential of CPI-0209
Journal Articles

Abstract 4351: Single-cell RNA sequencing reveals transcriptomic heterogeneity in response to epigenetic inhibitors

Andrew R. Conery, Sungmi Park, Michael J. Steinbaugh, Barbara M. Bryant, Shruti Apte, Patricia J. Keller, C. C. Yuan, Bill Bradley, Archana Bommi-Reddy, Robert J. Sims
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4351.
https://doi.org/10.1158/1538-7445.AM2019-4351
Published: 01 July 2019
View article titled, Abstract 4351: Single-cell RNA sequencing reveals transcriptomic heterogeneity in response to epigenetic inhibitors
Journal Articles

Abstract 4749: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma

Patricia J. Keller, Andrew R. Conery, Richard C. Centore, Archana Bommi-Reddy, Karen E. Gascoigne, Barbara M. Bryant, Jennifer A. Mertz, Robert J. Sims
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4749.
https://doi.org/10.1158/1538-7445.AM2016-4749
Published: 15 July 2016
View article titled, Abstract 4749: Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
Journal Articles

Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis

Lisa M. Arendt, Jessica McCready, Patricia J. Keller, Dana D. Baker, Stephen P. Naber, Victoria Seewaldt, Charlotte Kuperwasser
Journal: Cancer Research
Cancer Res (2013) 73 (19): 6080–6093.
https://doi.org/10.1158/0008-5472.CAN-13-0926
Published: 01 October 2013
View article titled, Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
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Includes: Supplementary data
Journal Articles

Abstract LB-265: Mutations in BRCA1 impair breast epithelial differentiation through the transcriptional repressor Slug

Patricia J. Keller, Theresa A. DiMeo, Piyush B. Gupta, Ina Klebba, Hannah Gilmore, Nadine Tung, Stephen P. Naber, Stuart Schnitt, Eric S. Lander, Charlotte Kuperwasser
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-265.
https://doi.org/10.1158/1538-7445.AM10-LB-265
Published: 15 April 2010
View article titled, Abstract LB-265: Mutations in BRCA1 impair breast epithelial differentiation through the transcriptional repressor Slug
Journal Articles

PRL Tyrosine Phosphatases Regulate Rho Family GTPases to Promote Invasion and Motility

James J. Fiordalisi, Patricia J. Keller, Adrienne D. Cox
Journal: Cancer Research
Cancer Res (2006) 66 (6): 3153–3161.
https://doi.org/10.1158/0008-5472.CAN-05-3116
Published: 15 March 2006
View article titled, PRL Tyrosine Phosphatases Regulate Rho Family GTPases to Promote Invasion and Motility
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Journal Articles

Rac3-Mediated Transformation Requires Multiple Effector Pathways

Patricia J. Keller, Christyn M. Gable, Michele R. Wing, Adrienne D. Cox
Journal: Cancer Research
Cancer Res (2005) 65 (21): 9883–9890.
https://doi.org/10.1158/0008-5472.CAN-04-3116
Published: 01 November 2005
View article titled, Rac3-Mediated Transformation Requires Multiple Effector Pathways
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