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Padhma Radhakrishnan
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Journal Articles

Abstract LB-286: An ex-vivo tumor platform used to predict clinical trial efficacy: Pembrolizumab+Pt+5-FU vs. EXTREME in recurrent head and neck squamous cell carcinoma

Saravanan Thyiagarajan, Biswanath Majumder, Abhisekh Basu, Padhma Radhakrishnan, Manjusha Biswas, Munisha Smalley, Hans Gertje, Parker Cassidy, Mark Lawson, KS Sabitha, Govind Babu, Aaron J. Goldman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-286.
https://doi.org/10.1158/1538-7445.AM2018-LB-286
Published: 01 July 2018
View article titled, Abstract LB-286: An <em>ex-vivo</em> tumor platform used to predict clinical trial efficacy: Pembrolizumab+Pt+5-FU vs. EXTREME in recurrent head and neck squamous cell carcinoma
Journal Articles

Abstract 705: Nonuniform T-cell infiltration induced by PD-1 checkpoint blockade, ex vivo, predicts distinct clinical response

Munisha Smalley, Basavaraja Shanthappa, Hans Gertje, Mark Lawson, Baraneedharan Ulaganathan, Allen Thayakumar, D.C. Doval, Anurag Mehta, S. P. Somashekhar, Padhma Radhakrishnan, Pradip Majumder, Aaron J. Goldman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 705.
https://doi.org/10.1158/1538-7445.AM2018-705
Published: 01 July 2018
View article titled, Abstract 705: Nonuniform T-cell infiltration induced by PD-1 checkpoint blockade, <em>ex vivo,</em> predicts distinct clinical response
Journal Articles

Abstract 3681: A patient derived ex vivo platform CANScript™ predicts distinct therapeutic outcomes to multiple PD-1 checkpoint inhibitors in single tumor biopsies

Padhma Radhakrishnan, Vasanthakumar Sekar, Nilesh Brijwani, Priyanka Chevour, Babu Balakrishnan, Dency D Pinto, Muthusami Oliyarasi, Debapriya G. Mehrotra, Manjusha Biswas, Sabitha K S, Kodaganur S. Gopinath, Arkasubhra Ghosh, M s Ganesh, Ashok M. Shenoy, Saravanan Thiyagarajan, Biswanath Majumder, Aaron Goldman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3681.
https://doi.org/10.1158/1538-7445.AM2017-3681
Published: 01 July 2017
View article titled, Abstract 3681: A patient derived <em>ex vivo</em> platform CANScript™ predicts distinct therapeutic outcomes to multiple PD-1 checkpoint inhibitors in single tumor biopsies
Journal Articles

Abstract 3397: Intrinsic factors from patient's tumor help neovascularization in an ex vivo platform

Baraneedharan Ulaganathan, Allen Thayakumar B, Manoj Rajappa, Ayyappan Velu, Arun Prasath, Kamal Ameer, Nilesh Brijwani, Padhma Radhakrishnan, Biswanath Majumder, Pradip K. Majumder, Saravanan Thiyagarajan
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3397.
https://doi.org/10.1158/1538-7445.AM2016-3397
Published: 15 July 2016
View article titled, Abstract 3397: Intrinsic factors from patient's tumor help neovascularization in an ex vivo platform
Journal Articles

Abstract 5121: Immunomodulating cytokine profiling of docetaxel-treated human prostate cancer specimens

Debapriya G. Mehrotra, Nilesh Brijwani, Biplab Tewary, Vasathkumar Sekar, Abhishek Krishnan, Dency D. Pinto, Muthusamy Oliyarasi, Biswanath Majumder, Saravanan Thiyagarajan, Padhma Radhakrishnan, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5121.
https://doi.org/10.1158/1538-7445.AM2016-5121
Published: 15 July 2016
View article titled, Abstract 5121: Immunomodulating cytokine profiling of docetaxel-treated human prostate cancer specimens
Journal Articles

Abstract 5129: Delineating immune networks in colorectal cancers to predict effects of immune checkpoint inhibitors using CANScript platform technology preserving tumor immune microenvironment

Pradip K. Majumder, Nilesh Brijwani, Nikita N. Karandikar, Vinod D. Radhakrishna, Muthusamy Oliyarasi, Dency D. Pinto, Babu Balakrishnan, Vasathakumar Sekar, Manoj Rajappa, Debapriya G. Mehrotra, Priyanka Chevur, Priyanka Chevur, Arkasubhra Ghosh, Saravanan Thyiagarajan, Padhma Radhakrishnan, Biswanath Majumder
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5129.
https://doi.org/10.1158/1538-7445.AM2016-5129
Published: 15 July 2016
View article titled, Abstract 5129: Delineating immune networks in colorectal cancers to predict effects of immune checkpoint inhibitors using CANScript platform technology preserving tumor immune microenvironment
Journal Articles

Abstract 1304: Identification of responders for Anti-CTLA4 in refractory colorectal cancers using CANScript™ platform

Biswanath Majumder, Baraneedharan Ulaganathan, Allen Thayakumar, Saravanan Thiyagarajan, Nilesh Brijwani, Biplab Tewari, Basavaraja U. Santhappa, Padhma Radhakrishnan, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1304.
https://doi.org/10.1158/1538-7445.AM2015-1304
Published: 01 August 2015
View article titled, Abstract 1304: Identification of responders for Anti-CTLA4 in refractory colorectal cancers using CANScript™ platform
Journal Articles

Abstract 1478: Development of novel Mi-HTX in vivo platform by reconstituting autologous immune components in patient tumor-derived xenografts

Saravanan Thiyagarajan, Padhma Radhakrishnan, Vinod D Radhakrishna, Dency D Pinto, Biswanath Majumder
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1478.
https://doi.org/10.1158/1538-7445.AM2015-1478
Published: 01 August 2015
View article titled, Abstract 1478: Development of novel Mi-HTX in vivo platform by reconstituting autologous immune components in patient tumor-derived xenografts
Journal Articles

Abstract 3736: Application of patient tumors-derived tumor ecosystem platform for the development of novel HDAC inhibitor in solid cancers

Mallikarjun Sundaram, Baraneedharan Ulaganathan, Muthu Dhandapani, Allen Thayakumar, Pragnashree Mukhopadhyay, Saravanan Thiyagarajan, Biswanath Majumder, Prasad Shivarudriah, H Jagadheshan, Ganesh Sambasivam, Steve Birnbuam, Padhma Radhakrishnan, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3736.
https://doi.org/10.1158/1538-7445.AM2014-3736
Published: 01 October 2014
View article titled, Abstract 3736: Application of patient tumors-derived tumor ecosystem platform for the development of novel HDAC inhibitor in solid cancers
Journal Articles

Abstract 2051: PAT-1102, a novel HDAC inhibitor exhibits potent anti-tumor efficacy in patient-derived refractory solid tumors.

Padhma Radhakrishnan, Muthu Dhandapani, Baraneedharan Ulaganathan, Allen Thayakumar, Saravanan Thiyagarajan, Dency Pinto, D R. Vinod, Biswanath Majumder, Prasad Shivarudriaah, H Jagadheshan, Ganesh Sambasivam, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2051.
https://doi.org/10.1158/1538-7445.AM2013-2051
Published: 15 April 2013
View article titled, Abstract 2051: PAT-1102, a novel HDAC inhibitor exhibits potent anti-tumor efficacy in patient-derived refractory solid tumors.
Journal Articles

Abstract 4947: Inhibition of Rapamycin induced AKT activation elicits differential anti-tumor response in head and neck cancers.

Padhma Radhakrishnan, Ulaganathan Baraneedharan, Muthu Dhandapani, Allen Thyakumar, Dency Pinto, Arun Prasath, Ayyappan Velu, A Kamal, Nilesh Brijwani, Rohini Nair, R Basavaraja, Misti Jain, Saravanan Thiyagarajan, Biswanath Majumder, Mallik Sundaram, Prasad Narayanan, Vikram D. Kekatpure, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4947.
https://doi.org/10.1158/1538-7445.AM2013-4947
Published: 15 April 2013
View article titled, Abstract 4947: Inhibition of Rapamycin induced AKT activation elicits differential anti-tumor response in head and neck cancers.
Journal Articles

Abstract 5072: Human tumor derived Oncoprint® platform predicts molecular mechanism of sensitivity and resistance to Fragmin in pancreatic cancer.

Mallikarjun Sundaram, Saravanan Thiyagarajan, Muthu Dhandapani, Nilesh Brijwani, Arun Prasath, Allen Thayakumar, Ameer Kamal, Padhma Radhakrishnan, Biswanath Majumder, Baraneedharan Ulaganathan, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5072.
https://doi.org/10.1158/1538-7445.AM2013-5072
Published: 15 April 2013
View article titled, Abstract 5072: Human tumor derived Oncoprint<sup>®</sup> platform predicts molecular mechanism of sensitivity and resistance to Fragmin in pancreatic cancer.
Journal Articles

Inhibition of Rapamycin-Induced AKT Activation Elicits Differential Antitumor Response in Head and Neck Cancers

Padhma Radhakrishnan, Ulaganathan Baraneedharan, Subhadra Veluchamy, Muthu Dhandapani, Dency D. Pinto, Saravanan Thiyagarajan, Allen Thayakumar, Arun Prasath, Kamal A, Ayyappan Velu, Misti Jain, Nilesh Brijwani, Prasad Narayanan, Vikram D. Kekatpure, Biswanath Majumder, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1118–1127.
https://doi.org/10.1158/0008-5472.CAN-12-2545
Published: 31 January 2013
View article titled, Inhibition of Rapamycin-Induced AKT Activation Elicits Differential Antitumor Response in Head and Neck Cancers
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Journal Articles

Abstract 3191: Primary human tumor-derived Oncoprint platform predicts molecular mechanism of sensitivity and resistance to anti-EGFR in colorectal cancer: A step towards personalized cancer medicine

Misti Jain, Farrah Zahed, Arun Prasath, Muthu Dhandapani, Subhadra Veluchamy, A Kamal, Padhma Radhakrishnan, Saravanan Thiyagarajan, Rajagopalan Surendran, Biswanath Mazumder, Mallik Sundaram, Pradip K. Majumder
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3191.
https://doi.org/10.1158/1538-7445.AM2012-3191
Published: 15 April 2012
View article titled, Abstract 3191: Primary human tumor-derived Oncoprint platform predicts molecular mechanism of sensitivity and resistance to anti-EGFR in colorectal cancer: A step towards personalized cancer medicine