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Journal Articles

Abstract 6217: TP53 loss with whole genome doubling mediates heterogeneous intra-patient therapy response in EGFR-driven lung adenocarcinoma: A TRACERx study

Sebastijan Hobor, Maise Al Bakir, Marcin Skrzypski, Alexander M. Frankell, Bjorn Bakker, Thomas B. Watkins, Aleksandra Markovets, Jonathan R. Dry, Andrew P. Brown, Jasper van der Aart, Dahmane Oukrif, Marco Novelli, Matthew J. Renshaw, William Hill, Hilda van den Bos, Diana C. Spierings, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Elza de Bruin, Floris Foijer, Karen H. Vousden, TRACERx consortium, Robert E. Hynds, Crispin T. Hiley, Nnennaya Kanu, Simone Zaccaria, Eva C. Gronroos, Charles Swanton
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6217.
DOI: https://doi.org/10.1158/1538-7445.AM2022-6217
Published: 15 June 2022
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Journal Articles

Abstract CT004: Adjuvant therapy with nivolumab (NIVO) combined with ipilimumab (IPI) vs NIVO alone in patients (pts) with resected stage IIIB-D/IV melanoma (CheckMate 915)

Georgina V. Long, Dirk Schadendorf, Michele Del Vecchio, James Larkin, Victoria Atkinson, Michael Schenker, Jacopo Pigozzo, Helen J. Gogas, Stéphane Dalle, Nicolas Meyer, Paolo A. Ascierto, Shahneen Sandhu, Thomas Eigentler, Ralf Gutzmer, Jessica C. Hassel, Caroline Robert, Matteo Carlino, Anna Maria Di Giacomo, Marcus O. Butler, Eva Muñoz-Couselo, Michael P. Brown, Piotr Rutkowski, Andrew Haydon, Jean-Jacques Grob, Jacob Schachter, Paola Queirolo, Alexander Menzies, Sandra Re, Tuba O. Bas, Veerle de Pril, Daniel Tenney, Hao Tang, Jeffrey S. Weber
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT004.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT004
Published: 01 July 2021
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Journal Articles

Abstract SP020: Beyond Hormones: Newer Pharmacologic Approaches

P Brown
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): SP020.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-SP20
Published: 15 February 2021
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Journal Articles

Abstract PO-026: Analysis of metabolic adaptations in HeLa cells as a function of energy status using a novel, direct ATP chelation methodology

Ashley P. Brown, Taha Muhammad, Selina Martinez, Shaleen B. Korch, Jeffrey Norris
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-026.
DOI: https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-026
Published: 02 December 2020
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Journal Articles

Abstract 930: On-target resistance to mutant selective EGFR inhibitors develops in an allele-specific manner dependent on the original EGFR activating mutation

Yunkai Zhang, Benjamin P. Brown, David Westover, Yingjun Yan, Huan Qiao, Vincent Huang, Zhenfang Du, Jarrod A. Smith, Jeffrey S. Ross, Vincent A. Miller, Siraj Ali, Lyudmila Bazhenova, Alexa B. Schrock, Jens Meiler, Christine M. Lovly
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 930.
DOI: https://doi.org/10.1158/1538-7445.AM2019-930
Published: 01 July 2019
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Journal Articles

Abstract CT013: Osimertinib displays high brain exposure in healthy subjects with intact blood-brain barrier: a microdose positron emission tomography (PET) study with 11C-labelled osimertinib

Karthick Vishwanathan, Andrea Varrone, Katarina Varnas, Aurelija Jucaite, Zsolt Cselenyi, Peter Johnstrom, Magnus Schou, Ana Vasquez-Romero, Mohammed Mahdi Moein, Christer Halldin, Andrew P. Brown, Lars Farde
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT013.
DOI: https://doi.org/10.1158/1538-7445.AM2018-CT013
Published: 01 July 2018
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Journal Articles

Abstract ES5-2: ES5-2 Non-endocrine strategies: Beyond the estrogen receptor

P Brown
Journal: Cancer Research
Cancer Res (2017) 77 (4_Supplement): ES5-2.
DOI: https://doi.org/10.1158/1538-7445.SABCS16-ES5-2
Published: 15 February 2017
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Journal Articles

Abstract P1-08-04: SOX9 is a critical regulator of triple-negative breast cancer cell growth and invasion

Y Ma, J Shepherd, A Mazumdar, D Zhao, L Bollu, J Hill, Y Zhang, P Brown
Journal: Cancer Research
Cancer Res (2017) 77 (4_Supplement): P1-08-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS16-P1-08-04
Published: 15 February 2017
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Journal Articles

Abstract 3159: In vitro characterization of third-generation chimeric antigen receptor T cells directed toward GD2-expressing and BRAF-inhibitor resistant melanoma target cells

Tessa Gargett, Michael P. Brown
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3159.
DOI: https://doi.org/10.1158/1538-7445.AM2015-3159
Published: 01 August 2015
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Journal Articles

Nutlin-3a Efficacy in Sarcoma Predicted by Transcriptomic and Epigenetic Profiling

Kathleen I. Pishas, Susan J. Neuhaus, Mark T. Clayer, Andreas W. Schreiber, David M. Lawrence, Michelle Perugini, Robert J. Whitfield, Gelareh Farshid, Jim Manavis, Steve Chryssidis, Bronwen J. Mayo, Rebecca C. Haycox, Kristen Ho, Michael P. Brown, Richard J. D'Andrea, Andreas Evdokiou, David M. Thomas, Jayesh Desai, David F. Callen, Paul M. Neilsen
Journal: Cancer Research
Cancer Res (2014) 74 (3): 921–931.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-2424
Published: 02 February 2014
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Includes: Supplementary data
Journal Articles

Abstract P6-04-04: Maternal embryonic leucine zipper kinase (MELK) is a novel radiosensitizing and therapeutic target and is independently prognostic in triple-negative breast cancer

C Speers, M Liu, P Alluri, N Batra, P Brown, L Pierce, F Feng
Journal: Cancer Research
Cancer Res (2013) 73 (24_Supplement): P6-04-04.
DOI: https://doi.org/10.1158/0008-5472.SABCS13-P6-04-04
Published: 15 December 2013
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Journal Articles

Abstract P3-10-23: Caveolin 1 and Patient Outcomes in Breast Cancer

RM Bambury, A-M Gonzalez-Angulo, MS Carey, A Sahin, P Brown, C Speers, A Lluch, GB Mills, BT Hennessy
Journal: Cancer Research
Cancer Res (2010) 70 (24_Supplement): P3-10-23.
DOI: https://doi.org/10.1158/0008-5472.SABCS10-P3-10-23
Published: 15 December 2010
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Journal Articles

Identification of Critical Transducers of Rexiniod-Mediated Growth Suppression in Normal Breast Cells.

J. Rodenberg, I. Uray, R. Bissonnette, P. Brown
Journal: Cancer Research
Cancer Res (2009) 69 (24_Supplement): 3134.
DOI: https://doi.org/10.1158/0008-5472.SABCS-09-3134
Published: 15 December 2009
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Journal Articles

PRSS23 Is an Estrogen Induced, AP-1-Dependent Gene in MCF-7 Breast Cancer Cells.

J. Mayer, C. Wang, J. Rodenberg, P. Brown
Journal: Cancer Research
Cancer Res (2009) 69 (24_Supplement): 1131.
DOI: https://doi.org/10.1158/0008-5472.SABCS-09-1131
Published: 15 December 2009
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Journal Articles

A Single Nucleotide Polymorphism in Steroid Receptor Coactivator-1 Diminishes the Coactivation of ERα.

R. Hartmaier, R. Hartmaier, R. Hartmaier, A. Richter, A. Richter, A. Richter, S. McGuire, S. McGuire, J. Wang, A. Lee, A. Lee, A. Lee, C. Osborne, C. Osborne, B. O'Malley, P. Brown, P. Brown, P. Brown, J. Xu, T. Skaar, T. Skaar, S. Philips, S. Philips, J. Rae, J. Rae, F. Azzouz, F. Azzouz, L. Li, L. Li, N. Henry, N. Henry, A. Nguyen, A. Nguyen, V. Stearns, V. Stearns, D. Hayes, D. Hayes, D. Flockhart, D. Flockhart, S. Oesterreich, S. Oesterreich, S. Oesterreich, S. Oesterreich
Journal: Cancer Research
Cancer Res (2009) 69 (24_Supplement): 66.
DOI: https://doi.org/10.1158/0008-5472.SABCS-09-66
Published: 15 December 2009
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Journal Articles

Pharmacologic inhibitors of the MEK-MAP kinase pathway are associated with toxicity to the skin, stomach, intestines, and liver

Alan P. Brown, James F. Reindel, Lonnie Grantham, Cho-Ming Loi, Keri Van Becelaere, Judy Leopold, Michael J. Graziano
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 308.
Published: 15 April 2006
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Journal Articles

Cutaneous lesions in the rat following administration of an irreversible pan-erbB receptor inhibitor

Alan P. Brown, Robert W. Dunstan, Cynthia L. Courtney, Kay A. Criswell, Michael J. Graziano
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 308.
Published: 15 April 2006
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Journal Articles

Pharmacologic inhibition of the MEK-MAP kinase signal transduction pathway in the rat.

Alan P. Brown, Tage Carlson, Cho-Ming Loi, Michael J. Graziano
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 489.
Published: 01 April 2004
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Journal Articles

Evaluation of the medicinal botanical Rhodiola rosea for estrogenicity

Patricia K. Eagon, Mary S. Elm, Patricia L. Gerbarg, Richard P. Brown, Jennifer J. Check, Gregory J. Diorio, Frank Houghton, Jr
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 663.
Published: 01 April 2004
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Journal Articles

BR96 sFv-PE40, a Potent Single-Chain Immunotoxin That Selectively Kills Carcinoma Cells

Paula N. Friedman, Stephen J. McAndrew, Susan L. Gawlak, Dana Chace, Pamela A. Trail, Joseph P. Brown, Clay B. Siegall
Journal: Cancer Research
Cancer Res (1993) 53 (2): 334–339.
Published: 01 January 1993
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