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Journal Articles

Abstract LB-251: The cancer clinical trial landscape in the EU and the Nordic countries

Jeroen Pouwels, Sebastian Soidinsalo, Heidi Haikala, Panu Jaakola, Tarja Jalava, Heikki Joensuu, Mika Mustonen, Pasi Korhonen, Panu Kovanen, Anne Lehtonen, Johanna Mattson, Outi Monni, Jukka Westermarck, Juha Klefström
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-251.
https://doi.org/10.1158/1538-7445.AM2019-LB-251
Published: 01 July 2019
View article titled, Abstract LB-251: The cancer clinical trial landscape in the EU and the Nordic countries
Journal Articles

Abstract 1698: Systems pathology for characterization of cancer model systems in a multicenter IMI-PREDECT project

Sami Blom, Yinhai Wang, Tauno Metsalu, Tiina Vesterinen, Teijo Pellinen, Anne Grote, Nina Linder, Jenni Säilä, Katja Välimäki, Ruusu-Maria Kovanen, Outi Monni, Panu Kovanen, Emma Davies, Kristin Stock, Marta Estrada, Georgios Sflomos, Sylvia Grünewald, Catarina Brito, Julia Schüler, Ronald de Hoogt, Cathrin Brisken, Heiko van der Kuip, Wytske van Weerden, Simon Barry, Wolgang Sommergruber, Elizabeth Anderson, Matthias Nees, Juha Klefström, Jaak Vilo, Emmy Verschuren, Ralph Graeser, John Hickman, Johan Lundin, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1698.
https://doi.org/10.1158/1538-7445.AM2015-1698
Published: 01 August 2015
View article titled, Abstract 1698: Systems pathology for characterization of cancer model systems in a multicenter IMI-PREDECT project
Journal Articles

Abstract 1188: Primary human breast tumor explant platform for integrated profiling and target validation

Liina Nevalaita, Hanna Ala-Hongisto, Maria Lehtivaara, Päivi Heikkilä, Marjut Leidenius, Panu Kovanen, Outi Monni, Juha Klefström
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1188.
https://doi.org/10.1158/1538-7445.AM2014-1188
Published: 01 October 2014
View article titled, Abstract 1188: Primary human breast tumor explant platform for integrated profiling and target validation
Journal Articles

Abstract 4933: Functional properties of PPFIA1, located at the 11q13 amplification region, in epithelial cancer cells.

Henna Pehkonen, Tatiana Lepikhova, Riku Louhimo, Nina Peitsaro, Misa Imai, Rafael Martinez, Juha Kleftsröm, Sampsa Hautaniemi, Outi Monni
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4933.
https://doi.org/10.1158/1538-7445.AM2013-4933
Published: 15 April 2013
View article titled, Abstract 4933: Functional properties of PPFIA1, located at the 11q13 amplification region, in epithelial cancer cells.
Journal Articles

Abstract 1628: Molecular cross-talk between head and neck squamous cell carcinoma cells and cancer-associated fibroblasts.

Anna Ansell, Matti Kankainen, Outi Monni, Ann-Charlotte Johansson
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1628.
https://doi.org/10.1158/1538-7445.AM2013-1628
Published: 15 April 2013
View article titled, Abstract 1628: Molecular cross-talk between head and neck squamous cell carcinoma cells and cancer-associated fibroblasts.
Journal Articles

Abstract 4836: In vitro drug sensitivity testing along with full genome and transcriptome sequencing and phosphoproteomics: Comprehensive “next-generation” molecular oncology portrait of a sarcoma for facilitating treatment decisions

For the Individualized Medicine Collaboration, Caroline Heckman, Kari Alitalo, Leif Andersson, Peter Campbell, Henrik Edgren, Andy Futreal, Tanja Holopainen, Paul Huang, Heikki Joensuu, Olli Kallioniemi, Sara Kangaspeska, Sami Kilpinen, Jami Mandelin, Outi Monni, Astrid Murumägi, Daniel Nicorici, Arto Orpana, Merja Perälä, Maarit Sarlomo-Rikala, Mike Stratton, Forest White
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4836.
https://doi.org/10.1158/1538-7445.AM2011-4836
Published: 15 April 2011
View article titled, Abstract 4836: In vitro drug sensitivity testing along with full genome and transcriptome sequencing and phosphoproteomics: Comprehensive “next-generation” molecular oncology portrait of a sarcoma for facilitating treatment decisions
Journal Articles

Abstract #2591: Defining amplification target genes in epithelial cancers by loss-of-function screen

Tatyana Lepikhova, Iina Vuoristo, Sauli Kyttänen, Topi Tervonen, Juha Klefström, Outi Monni
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2591.
Published: 01 May 2009
View article titled, Abstract #2591: Defining amplification target genes in epithelial cancers by loss-of-function screen
Journal Articles

A novel array-based “DNA/RNA outlier analysis” distinguishes key pathogenetic genes and novel therapeutic targets in breast cancer.

Henrik Edgren, Maija Wolf, Rolf Skotheim, Sami Kilpinen, Reija Autio, Aslaug Muggerud, Therese Sörlie, Kristiina Iljin, Outi Monni, Saija Haapa-Paananen, Merja Perälä, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1339.
Published: 15 April 2006
View article titled, A novel array-based “DNA/RNA outlier analysis” distinguishes key pathogenetic genes and novel therapeutic targets in breast cancer.
Journal Articles

PI3K/Akt pathway interference leads to specific gene expression alterations in breast cancer

Outi Monni, Sampsa Hautaniemi, Matti Saarela, Anni Nieminen, Juha Klefstrom, Anne Kallioniemi
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 978.
Published: 15 April 2006
View article titled, PI3K/Akt pathway interference leads to specific gene expression alterations in breast cancer
Journal Articles

Differentiation of Human Embryonal Carcinomas In vitro and In vivo Reveals Expression Profiles Relevant to Normal Development

Rolf I. Skotheim, Guro E. Lind, Outi Monni, Jahn M. Nesland, Vera M. Abeler, Sophie D. Fosså, Nur Duale, Gunnar Brunborg, Olli Kallioniemi, Peter W. Andrews, Ragnhild A. Lothe
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5588–5598.
https://doi.org/10.1158/0008-5472.CAN-05-0153
Published: 01 July 2005
View article titled, Differentiation of Human Embryonal Carcinomas <em>In vitro</em> and <em>In vivo</em> Reveals Expression Profiles Relevant to Normal Development
Open the PDF for Differentiation of Human Embryonal Carcinomas <em>In vitro</em> and <em>In vivo</em> Reveals Expression Profiles Relevant to Normal Development in another window
Includes: Supplementary data
Journal Articles

Bioinformatic tools to analyze gene copy number and expression alterations in head and neck cancer

Anna-Kaarina Järvinen, Reija Autio, Saija Haapa-Paananen, Matti Saarela, Maija Wolf, Henrik Edgren, Sampsa Hautaniemi, Ilmo Leivo, Reidar Grénman, Antti Mäkitie, Outi Monni
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 209–210.
Published: 01 May 2005
View article titled, Bioinformatic tools to analyze gene copy number and expression alterations in head and neck cancer
Journal Articles

Identification of putative target genes in gastric cancer by CGH and expression microarray analyses

Siina Junnila, Samuel Myllykangas, Arto Kokkola, Matti Saarela, Reija Autio, Juha Saharinen, Marja-Liisa Karjalainen-Lindsberg, Pauli Puolakkainen, Sakari Knuutila, Outi Monni
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 838–839.
Published: 01 May 2005
View article titled, Identification of putative target genes in gastric cancer by CGH and expression microarray analyses
Journal Articles

Bioinformatic analysis reveals an association of HOXB7 gene expression withoncogenic pathways and phenotypic properties in cancer

Sami K. Kilpinen, Reija Autio, Sampsa Hautaniemi, Outi Monni, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1109.
Published: 01 April 2004
View article titled, Bioinformatic analysis reveals an association of HOXB7 gene expression withoncogenic pathways and phenotypic properties in cancer
Journal Articles

Identification of druggable genes in cancer using bioinformatic analysis of CGH and cDNA microarray data.

Henrik Edgren, Maija Wolf, Sampsa Hautaniemi, Spyro Mousses, Pia Huusko, Minna Allinen, Abdel Elkahloun, Outi Monni, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 756–757.
Published: 01 April 2004
View article titled, Identification of druggable genes in cancer using bioinformatic analysis of CGH and cDNA microarray data.
Journal Articles

High-resolution genome-wide copy number and expression profiling reveals putative new amplification target genes in pancreatic cancer.

Anne H. Kallioniemi, Eija H. Mahlamaki, Paivikki Kauraniemi, Outi Monni, Maija Wolf, Sampsa Hautaniemi
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 795.
Published: 01 April 2004
View article titled, High-resolution genome-wide copy number and expression profiling reveals putative new amplification target genes in pancreatic cancer.
Journal Articles

High-resolution genome-wide copy number and expression profiling of squamous cell carcinoma of head and neck

Anna-Kaarina Jarvinen, Ilmo Leivo, Maija Wolf, Sampsa Hautaniemi, Reidar Grénman, Antti Makitie, Outi Monni
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 655.
Published: 01 April 2004
View article titled, High-resolution genome-wide copy number and expression profiling of squamous cell carcinoma of head and neck
Journal Articles

High-resolution CGH microarray analysis in human prostate cancer: Impact of copy number changes on gene expression levels

Maija Wolf, Spyro Mousses, Sampsa Hautaniemi, Ritva Karhu, Pia Huusko, Minna Allinen, Abdel Elkahloun, Outi Monni, Anne Kallioniemi, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 655.
Published: 01 April 2004
View article titled, High-resolution CGH microarray analysis in human prostate cancer: Impact of copy number changes on gene expression levels
Journal Articles

Impact of DNA Amplification on Gene Expression Patterns in Breast Cancer

Elizabeth Hyman, Päivikki Kauraniemi, Sampsa Hautaniemi, Maija Wolf, Spyro Mousses, Ester Rozenblum, Markus Ringnér, Guido Sauter, Outi Monni, Abdel Elkahloun, Olli-P. Kallioniemi, Anne Kallioniemi
Journal: Cancer Research
Cancer Res (2002) 62 (21): 6240–6245.
Published: 01 November 2002
View article titled, Impact of DNA Amplification on Gene Expression Patterns in Breast Cancer
Open the PDF for Impact of DNA Amplification on Gene Expression Patterns in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Targets of Gene Amplification and Overexpression at 17q in Gastric Cancer

Asta Varis, Maija Wolf, Outi Monni, Marja-Leena Vakkari, Arto Kokkola, Chris Moskaluk, Henry Frierson, Jr., Steven M. Powell, Sakari Knuutila, Anne Kallioniemi, Wa’el El-Rifai
Journal: Cancer Research
Cancer Res (2002) 62 (9): 2625–2629.
Published: 01 May 2002
View article titled, Targets of Gene Amplification and Overexpression at 17q in Gastric Cancer
Open the PDF for Targets of Gene Amplification and Overexpression at 17q in Gastric Cancer in another window
Journal Articles

New Insights into Testicular Germ Cell Tumorigenesis from Gene Expression Profiling

Rolf I. Skotheim, Outi Monni, Spyro Mousses, Sophie D. Fosså, Olli-P. Kallioniemi, Ragnhild A. Lothe, Anne Kallioniemi
Journal: Cancer Research
Cancer Res (2002) 62 (8): 2359–2364.
Published: 01 April 2002
View article titled, New Insights into Testicular Germ Cell Tumorigenesis from Gene Expression Profiling
Open the PDF for New Insights into Testicular Germ Cell Tumorigenesis from Gene Expression Profiling in another window