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Ouathek Ouerfelli
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Journal Articles

Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules

Kamini Singh, Jianan Lin, Nicolas Lecomte, Prathibha Mohan, Askan Gokce, Viraj R. Sanghvi, Man Jiang, Olivera Grbovic-Huezo, Antonija Burčul, Stefan G. Stark, Paul B. Romesser, Qing Chang, Jerry P. Melchor, Rachel K. Beyer, Mark Duggan, Yoshiyuki Fukase, Guangli Yang, Ouathek Ouerfelli, Agnes Viale, Elisa de Stanchina, Andrew W. Stamford, Peter T. Meinke, Gunnar Rätsch, Steven D. Leach, Zhengqing Ouyang, Hans-Guido Wendel
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (8): 2002–2014.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-2929
Published: 15 April 2021
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Includes: Supplementary data
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Abstract 1531: The Polycomb repressor complex 1 promotes recruitment of myeloid-derived suppressor cells and immune evasion during bone colonization in castration-resistant prostate cancer

Wenjing Su, Boyu Zhang, Hyunho Han, Goutam Chakraborty, Bing Zhou, Jie Su, Guangli Yang, Ouathek Ouerfelli, Neal Rosen, Howard I. Scher, Filippo G. Giancotti
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1531.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1531
Published: 01 July 2019
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Journal Articles

Abstract 4975: A small molecule pan Id protein antagonist shows strong antitumor activity

Paulina M. Wojnarowicz, Bina Desai, Yvette Chin, Sang Bae Lee, Marta Garcia-Cao, Ouathek Ouerfelli, Guangli Yang, Sijia Xu, Yehuda Goldgur, Meredith A. Miller, Jaideep Chaudhary, William A. Garland, Steven K. Albanese, Rajesh Soni, John Philip, Larry Norton, Neal Rosen, Ronald C. Hendrickson, Xi Kathy Zhou, Antonio Iavarone, Andrew J. Dannenberg, John D. Chodera, Nikola Pavletich, Anna Lasorella, Robert Benezra
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4975.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4975
Published: 01 July 2017
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Journal Articles

Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors

Neerav Shukla, Romel Somwar, Roger S. Smith, Sri Ambati, Stanley Munoz, Melinda Merchant, Padraig D'Arcy, Xin Wang, Rachel Kobos, Christophe Antczak, Bhavneet Bhinder, David Shum, Constantin Radu, Guangbin Yang, Barry S. Taylor, Charlotte K.Y. Ng, Britta Weigelt, Inna Khodos, Elisa de Stanchina, Jorge S. Reis-Filho, Ouathek Ouerfelli, Stig Linder, Hakim Djaballah, Marc Ladanyi
Journal: Cancer Research
Cancer Res (2016) 76 (15): 4525–4534.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-1040
Published: 31 July 2016
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Includes: Supplementary data
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Abstract PR09: High-throughput chemical screening identifies a novel class of proteasome inhibitors with significant activity against Ewing sarcoma

Neerav Shukla, Romel Somwar, Srikanth Ambati, Roger S. Smith, Melinda Merchant, Rachel Kobos, Ouathek Ouerfelli, Hakim Djaballah, Marc Ladanyi
Journal: Cancer Research
Cancer Res (2014) 74 (20_Supplement): PR09.
DOI: https://doi.org/10.1158/1538-7445.PEDCAN-PR09
Published: 09 October 2014
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Journal Articles

Abstract 2926: PNA as novel targeted cancer therapy for BRAFV600E mutant melanoma

Jeffrey H. Rothman, Oliver Surriga, Shyamprasad D. Vasudeva, Grazia Ambrosini, Ouathek Ouerfelli, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2926.
DOI: https://doi.org/10.1158/1538-7445.AM2014-2926
Published: 01 October 2014
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Journal Articles

Abstract 1828: Identification of MUC16/CA125-specific therapeutics through dual fluorescence high throughput screening

Dharmarao Thapi, Sahityasri Thapi, Nestor Rosales, Christophe Antczak, Ouathek Ouerfelli, David R. Spriggs, Hakim Djaballah
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1828.
DOI: https://doi.org/10.1158/1538-7445.AM2012-1828
Published: 15 April 2012
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Journal Articles

Abstract 3033: Identification of the MUC16/CA125 interaction network: Results of a high-throughput yeast two-hybrid screening

Stephan Polterauer, Dharmarao Thapi, Nikolaus Schultz, Ouathek Ouerfelli, Nancy Chen, Nestor Rosales, Xiu Yan, David R. Spriggs
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3033.
DOI: https://doi.org/10.1158/1538-7445.AM2012-3033
Published: 15 April 2012
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Journal Articles

ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment

Nicola J. Clegg, John Wongvipat, James D. Joseph, Chris Tran, Samedy Ouk, Anna Dilhas, Yu Chen, Kate Grillot, Eric D. Bischoff, Ling Cai, Anna Aparicio, Steven Dorow, Vivek Arora, Gang Shao, Jing Qian, Hong Zhao, Guangbin Yang, Chunyan Cao, John Sensintaffar, Teresa Wasielewska, Mark R. Herbert, Celine Bonnefous, Beatrice Darimont, Howard I. Scher, Peter Smith-Jones, Mark Klang, Nicholas D. Smith, Elisa De Stanchina, Nian Wu, Ouathek Ouerfelli, Peter J. Rix, Richard A. Heyman, Michael E. Jung, Charles L. Sawyers, Jeffrey H. Hager
Journal: Cancer Research
Cancer Res (2012) 72 (6): 1494–1503.
DOI: https://doi.org/10.1158/0008-5472.CAN-11-3948
Published: 14 March 2012
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Includes: Supplementary data
Journal Articles

Abstract #3413: A new pathway for processing mitochondrial-DNA encoded proteins is essential to mitochondrial energy production in human cancer cells

Sindy Escobar Alvarez, Jeffrey Gardner, Aneesh Sheth, Guangli Yang, Ouathek Ouerfelli, Giovanni Manfredi, Mark Heaney, David Scheinberg
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3413.
Published: 01 May 2009
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Journal Articles

Abstract #2085: EGFR T790M-driven murine lung tumors respond to dual EGFR targeting with cetuximab and BIBW-2992

Lucia Regales, Yixuan Gong, Katerina Politi, Ronglai Shen, Maria Spassova, Ouathek Ouerfelli, William Pao
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2085.
Published: 01 May 2009
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Journal Articles

Crystal structure of a new cancer target, human peptide deformylase with its inhibitor

Sindy Escobar Alvarez, Yehuda Goldgur, Christophe Antczak, Guangli Yang, Ouathek Ouerfelli, Hakim Djaballah, Yueming Li, David Scheinberg
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1639.
Published: 01 May 2007
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