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Olli Kallioniemi
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Journal Articles

Abstract 6481: Multiplexed single-cell pharmacotranscriptomics and spatial tumor biology reveals targetable reciprocal cancer-stromal interactions in prostate cancer

Free
Astrid Murumägi, Frida Rantanen, Alice Dini, Mariliina Arjama, Katja Välimäki, Elina Multamäki, Tuomas Mirtti, Antti Rannikko, Teijo Pellinen, Daniela Ungureanu, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6481.
https://doi.org/10.1158/1538-7445.AM2025-6481
Published: 21 April 2025
View articletitled, Abstract 6481: Multiplexed single-cell pharmacotranscriptomics and spatial tumor biology reveals targetable reciprocal cancer-stromal interactions in prostate cancer
Journal Articles

Abstract B026: Leveraging patient-derived models to identify novel treatment options in high-grade serous ovarian cancer

Free
Greta Gudoityte, Olena Berkovska, Lukas Orre, Elisabeth Moussaud-Lemoderie, Josefin Fernebro, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore-Ludlow
Journal: Cancer Research
Cancer Res (2025) 85 (5_Supplement): B026.
https://doi.org/10.1158/1538-7445.GENFUNC25-B026
Published: 11 March 2025
View articletitled, Abstract B026: Leveraging patient-derived models to identify novel treatment options in high-grade serous ovarian cancer
Journal Articles

Abstract A017: Enhanced efficacy of anti-mesothelin CAR T cells in ovarian cancer through drug combinations: Impact of treatment kinetics, co-stimulatory domain, and donor variability

Free
Lucía Rico Pizarro, Thomas Poiret, Greta Gudoitytė, Olli Kallioniemi, Brinton Seashore-Ludlow, Isabelle Magalhaes, Tom Erkers
Journal: Cancer Research
Cancer Res (2025) 85 (5_Supplement): A017.
https://doi.org/10.1158/1538-7445.GENFUNC25-A017
Published: 11 March 2025
View articletitled, Abstract A017: Enhanced efficacy of anti-mesothelin CAR T cells in ovarian cancer through drug combinations: Impact of treatment kinetics, co-stimulatory domain, and donor variability
Journal Articles

Abstract 5490: Spatial profiling of inflamed tumor microenvironment of clear cell renal cell carcinoma

Free
Teijo Pellinen, Lassi Luomala, Kalle Mattila, Jenni Säilä, Annabrita Hemmes, Katja Valimaki, Oscar Bruck, Lassi Paavolainen, Harry Nisen, Petrus Järvinen, Olli Kallioniemi, Paula Vainio, Panu Jaakkola, Tuomas Mirtti
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5490.
https://doi.org/10.1158/1538-7445.AM2024-5490
Published: 22 March 2024
View articletitled, Abstract 5490: Spatial profiling of inflamed tumor microenvironment of clear cell renal cell carcinoma
Journal Articles

Abstract 4727: Large scale drug response comparison across different neuroblastoma cell model systems

Free
Se Whee Park, Ernest Liu, Aironas Los, Brinton Seashore-Ludlow, Päivi Östling, Jan Molenaar, Olli Kallioniemi, Jakob Stenman, Kasper Karlsson
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4727.
https://doi.org/10.1158/1538-7445.AM2024-4727
Published: 22 March 2024
View articletitled, Abstract 4727: Large scale drug response comparison across different neuroblastoma cell model systems
Journal Articles

Abstract 3100: Interactive analysis of drug testing data for functional precision oncology with Breeze 2.0

Free
Swapnil Potdar, Filipp Ianevski, Aleksandr Ianevski, Ziaurrehman Tanoli, Krister Wennerberg, Brinton Seashore-Ludlow, Olli Kallioniemi, Päivi Östling, Tero Aittokallio, Jani Saarela
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3100.
https://doi.org/10.1158/1538-7445.AM2024-3100
Published: 22 March 2024
View articletitled, Abstract 3100: Interactive analysis of drug testing data for functional precision oncology with Breeze 2.0
Journal Articles

Abstract 299: FAP/αSMA association with tumor visibility and progression in prostate cancer

Free
Jenni Säilä, Timo-Pekka Lehto, Annabrita Schoonenberg, Katja Välimäki, Andrew Erickson, Antti Rannikko, Olli Kallioniemi, Tuomas Mirtti, Teijo Pellinen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 299.
https://doi.org/10.1158/1538-7445.AM2024-299
Published: 22 March 2024
View articletitled, Abstract 299: FAP/αSMA association with tumor visibility and progression in prostate cancer
Journal Articles

Abstract 706: Advancing radiotherapy strategies for high-risk rhabdomyosarcoma: Unveiling BCL-xL inhibition as a potent sensitizer to radiotherapy

Free
Sammy Se Whee Park, Nona Struyf, Tom Erkers, Sören Lehmann, Michael T. Meister, Jarno Drost, Frank C. Holstege, Nikolas Herold, Päivi Östling, Jakob Stenman, Olli Kallioniemi, Jan-Inge Henter, Brinton Seashore-Ludlow, Kasper Karlsson
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 706.
https://doi.org/10.1158/1538-7445.AM2024-706
Published: 22 March 2024
View articletitled, Abstract 706: Advancing radiotherapy strategies for high-risk rhabdomyosarcoma: Unveiling BCL-xL inhibition as a potent sensitizer to radiotherapy
Journal Articles

Abstract 4459: Spatial profiling of the inflamed tumor microenvironment identifies novel prognostic subclasses in non-metastatic clear cell renal carcinoma patients

Free
Teijo Pellinen, Lassi Luomala, Kalle Mattila, Jenni Säilä, Annabrita Hemmes, Katja Välimäki, Oscar Bruck, Lassi Paavolainen, Harry Nisen, Petrus Järvinen, Olli Kallioniemi, Paula Vainio, Panu Jaakkola, Tuomas Mirtti
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4459.
https://doi.org/10.1158/1538-7445.AM2023-4459
Published: 04 April 2023
View articletitled, Abstract 4459: Spatial profiling of the inflamed tumor microenvironment identifies novel prognostic subclasses in non-metastatic clear cell renal carcinoma patients
Journal Articles

Abstract 2091: Open-source single-cell spatial image analysis pipeline for ten-plex immunofluorescence of histological prostate cancer tissue sections

Free
Jenni Säilä, Annabrita Schoonenberg, Katja Välimäki, Timo-Pekka Lehto, Carolin Stürenberg, Andrew Erickson, Antti Rannikko, Olli Kallioniemi, Lassi Paavolainen, Tuomas Mirtti, Teijo Pellinen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2091.
https://doi.org/10.1158/1538-7445.AM2023-2091
Published: 04 April 2023
View articletitled, Abstract 2091: Open-source single-cell spatial image analysis pipeline for ten-plex immunofluorescence of histological prostate cancer tissue sections
Journal Articles

Abstract 6612: Data-driven hallmarks of cancer as a new paradigm for precision medicine: multi-omics and functional profiling in acute myeloid leukemia

Free
Tom Erkers, Nona Struyf, Tojo James, Francesco Marabita, Mattias Vesterlund, Nghia Vu, Cornelia Arnroth, Albin Österroos, Anna Bohlin, Sofia Bengtzén, Matthias Stahl, Rozbeh Jafari, Lukas Orre, Yudi Pawitan, Brinton Seashore-Ludlow, Janne Lehtiö, Sören Lehmann, Päivi Östling, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6612.
https://doi.org/10.1158/1538-7445.AM2023-6612
Published: 04 April 2023
View articletitled, Abstract 6612: Data-driven hallmarks of cancer as a new paradigm for precision medicine: multi-omics and functional profiling in acute myeloid leukemia
Journal Articles

Abstract 1890: Development of the drug efficacy testing in ex vivo 3D cultures (DETECT) platform and its application to functional precision medicine in ovarian cancer

Free
Emma Åkerlund, Greta Gudoityte, Elisabeth Moussaud Lamodiere, Joseph Carlson, Emelie Wallin, Josefin Fernebro, Olli Kallioniemi, Päivi Östling, Ulrika Joneborg, Brinton Seashore-Ludlow
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1890.
https://doi.org/10.1158/1538-7445.AM2022-1890
Published: 15 June 2022
View articletitled, Abstract 1890: Development of the drug efficacy testing in ex vivo 3D cultures (DETECT) platform and its application to functional precision medicine in ovarian cancer
Journal Articles

Abstract 4134: Stromal FAP expression is associated with MRI visibility and patient survival in prostate cancer

Free
Teijo Pellinen, Kevin Smith, Sami Blom, Riku Turkki, Annabrita Hemmes, Katja Välimäki, Juho Eineluoto, Anu Kenttämies, Stig Nordling, Olli Kallioniemi, Antti Rannikko, Tuomas Mirtti
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4134.
https://doi.org/10.1158/1538-7445.AM2022-4134
Published: 15 June 2022
View articletitled, Abstract 4134: Stromal FAP expression is associated with MRI visibility and patient survival in prostate cancer
Journal Articles

Abstract 2945: Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling

Free
Astrid Murumägi, Daniela Ungureanu, Suleiman Khan, Akira Hirasawa, Mariliina Arjama, Katja Välimäki, Piia Mikkonen, Wilhelmiina Niininen, Ashwini Kumar, Samuli Eldfors, Teijo Pellinen, Vilja Pietiäinen, Andrus Mägi, Riitta Koivisto-Korander, Johanna Tapper, Mikko Loukovaara, Tero Aittokallio, Ralf Bützow, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2945.
https://doi.org/10.1158/1538-7445.AM2019-2945
Published: 01 July 2019
View articletitled, Abstract 2945: Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling
Journal Articles

Abstract 458: Precision systems medicine in acute myeloid leukemia: real-time translation of tailored therapeutic opportunities arising from ex-vivo drug sensitivity testing and molecular profiling

Free
Disha Malani, Ashwni Kumar, Bhagwan Yadav, Mika Kontro, Swapnil Potdar, Oscar Bruck, Säri Kytölä, Jani Saarela, Samuli Eldfors, Riikka Karjalainen, Muntasir M. Majumder, Imre Västrik, Pekka Ellonen, Matti Kankainen, Minna Suvela, Siv Knappila, Alun Parson, Aino Palva, Pirkko Mattila, Evgeny Kulesskiy, Laura Turunen, Karoliina Laamanen, Elina Lehtinen, Maria Nurmi, Katja Suomi, Astrid Muruimägi, Bjorn T. Gjertsen, Satu Mustjoki, Simon Anders, Maija Wolf, Tero Aittokallio, Krister Wennerberg, Caroline Heckman, Kimmo Porkka, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 458.
https://doi.org/10.1158/1538-7445.AM2019-458
Published: 01 July 2019
View articletitled, Abstract 458: Precision systems medicine in acute myeloid leukemia: real-time translation of tailored therapeutic opportunities arising from ex-vivo drug sensitivity testing and molecular profiling
Journal Articles

Abstract 5302: Phenotypic heterogeneity of patient-derived tumor cells visualized by unsupervised analysis in cell-based personalized drug testing

Free
Riku Turkki, Lassi Paavolainen, Piia Mikkonen, Päivi Östling, Peter Horvath, Vilja Pietiäinen, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5302.
https://doi.org/10.1158/1538-7445.AM2018-5302
Published: 01 July 2018
View articletitled, Abstract 5302: Phenotypic heterogeneity of patient-derived tumor cells visualized by unsupervised analysis in cell-based personalized drug testing
Journal Articles

Abstract 5029: Precision cancer medicine based on 3D drug profiling of patient-derived cancer cell spheroid models

Free
Piia Mikkonen, Laura Turunen, Lauri Paasonen, Swapnil Potdar, Lassi Paavolainen, Astrid Murumägi, Olli Kallioniemi, Vilja M. Pietiäinen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5029.
https://doi.org/10.1158/1538-7445.AM2018-5029
Published: 01 July 2018
View articletitled, Abstract 5029: Precision cancer medicine based on 3D drug profiling of patient-derived cancer cell spheroid models
Journal Articles

Abstract 2199: Establishment and high-throughput drug testing of multiple patient-derived cells from each renal cancer; intratumor heterogeneity of drug response and implications for precision medicine

Free
Khalid Saeed, Poojitha Ojamies, Teijo Pellinen, Samuli Eldfors, Riku Turkki, Johan Lundin, Harry Nisen, Petrus Järvinen, Kimmo Taari, Taija af Hällström, Antti Rannikko, Tuomas Mirtti, Olli Kallioniemi, Päivi Östling
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2199.
https://doi.org/10.1158/1538-7445.AM2018-2199
Published: 01 July 2018
View articletitled, Abstract 2199: Establishment and high-throughput drug testing of multiple patient-derived cells from each renal cancer; intratumor heterogeneity of drug response and implications for precision medicine
Journal Articles

Abstract 3899: Discovery and clinical implementation of individualized therapies in acute myeloid leukemia based on ex vivo drug sensitivity testing and multi-omics profiling

Free
Disha Malani, Ashwini Kumar, Bhagwan Yadav, Mika Kontro, Swapnil Potdar, Oscar Brück, Sari Kytölä, Jani Saarela, Samuli Eldfors, Poojitha Ojamies, Karjalainen Riikka, Muntasir Mamun Majumder, Imre Västrik, Pekka Ellonen, Matti Kankainen, Minna Suvela, Siv Knappila, Alun Parson, Aino Palva, Pirkko Mattila, Evgeny Kulesskiy1, Laura Turunen, Karoliina Laamanen, Elina Lehtinen, Piia Mikkonen, Maria Nurmi, Sanna Timonen, Astrid Murumägi, Bjorn Tore Gjersten, Satu Mustjoki, Tero Aittokallio, Krister Wennerberg, Simon Anders, Maija Wolf, Caroline Heckman, Kimmo Porkka, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3899.
https://doi.org/10.1158/1538-7445.AM2018-3899
Published: 01 July 2018
View articletitled, Abstract 3899: Discovery and clinical implementation of individualized therapies in acute myeloid leukemia based on ex vivo drug sensitivity testing and multi-omics profiling
Journal Articles

Abstract 286: Transcriptomic features predicting drug sensitivity and resistance in acute myeloid leukemia

Free
Ashwini Kumar, Disha Malani, Bhagwan Yadav, Mika Kontro, Matti Kankainen, Swapnil Potdar, Simon Anders, Kimmo Porkka, Olli Kallioniemi Kallioniemi, Caroline Heckman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 286.
https://doi.org/10.1158/1538-7445.AM2018-286
Published: 01 July 2018
View articletitled, Abstract 286: Transcriptomic features predicting drug sensitivity and resistance in acute myeloid leukemia