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Journal Articles

The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma

Praneeth Reddy Sudalagunta, Rafael R. Canevarolo, Mark B. Meads, Maria Silva, Xiaohong Zhao, Christopher L. Cubitt, Samer S. Sansil, Gabriel DeAvila, Raghunandan Reddy Alugubelli, Ryan T. Bishop, Alexandre Tungesvik, Qi Zhang, Oliver Hampton, Jamie K. Teer, Eric A. Welsh, Sean J. Yoder, Bijal D. Shah, Lori Hazlehurst, Robert A. Gatenby, Dane R. Van Domelen, Yi Chai, Feng Wang, Andrew DeCastro, Amanda M. Bloomer, Erin M. Siegel, Conor C. Lynch, Daniel M. Sullivan, Melissa Alsina, Taiga Nishihori, Jason Brayer, John L. Cleveland, William Dalton, Christopher J. Walker, Yosef Landesman, Rachid Baz, Ariosto S. Silva, Kenneth H. Shain
Journal: Cancer Research
Cancer Res (2025) 85 (2): 378–398.
https://doi.org/10.1158/0008-5472.CAN-24-0886
Published: 15 January 2025
View article titled, The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma
Open the PDF for The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Abstract 3928: Genomic landscape and estimation of immune infiltration of soft tissue sarcoma histology subtypes from the ORIEN network

Alex C. Soupir, Oscar E. Ospina, Dale Hedges, Jamie K. Teer, Michael D. Radmacher, David M. McKean, Nathan Seligson, Martin McCarter, Breelyn Wilkey, Greg Riedlinger, John Groundland, Benjamin J. Miller, Bryan Schneider, Reema Patel, Abdul Rafeh-Naqash, Stephen Edge, Bodour Salhia, Chris Moskaluk, Maggy Johns, Michelle L. Churchman, Oliver Hampton, David Liebner, Brooke L. Fridley, Andrew S. Brohl
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3928.
https://doi.org/10.1158/1538-7445.AM2024-3928
Published: 22 March 2024
View article titled, Abstract 3928: Genomic landscape and estimation of immune infiltration of soft tissue sarcoma histology subtypes from the ORIEN network
Journal Articles

CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma

Karen L. Burger, Mario R. Fernandez, Mark B. Meads, Praneeth Sudalagunta, Paula S. Oliveira, Rafael Renatino Canevarolo, Raghunandan Reddy Alugubelli, Alexandre Tungsevik, Gabe De Avila, Maria Silva, Allison I. Graeter, Hongyue A. Dai, Nicole D. Vincelette, Antony Prabhu, Dario Magaletti, Chunying Yang, Weimin Li, Amit Kulkarni, Oliver Hampton, John M. Koomen, William R. Roush, Andrii Monastyrskyi, Anders E. Berglund, Ariosto S. Silva, John L. Cleveland, Kenneth H. Shain
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3901–3919.
https://doi.org/10.1158/0008-5472.CAN-22-2350
Published: 01 December 2023
View article titled, CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma
Open the PDF for CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Abstract 5453: Individualized risk stratification in newly diagnosed multiple myeloma

Arjun Raj Rajanna, Francesco Maura, Andriy Derkach, Bachisio Ziccheddu, Niels Weinhold, Kylee Maclachlan, Benjamin Diamond, Faith Davies, Eileen Boyle, Brian Walker, Alexandra Pos, Malin Hulcrantz, Ariosto Silva, Oliver Hampton, Jamie K. Teer, Niccolò Bolli, Graham Jackson, Martin Kaiser, Charlotte Pawlyn, Gordon Cook, Dennis Verducci, Dickran Kazandjian, Fritz Van Rhee, Saad Usmani, Kenneth H. Shain, Marc S. Raab, Gareth Morgan, Ola Landgren
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5453.
https://doi.org/10.1158/1538-7445.AM2023-5453
Published: 04 April 2023
View article titled, Abstract 5453: Individualized risk stratification in newly diagnosed multiple myeloma
Journal Articles

Abstract 1061: Characterization of synergistic selinexor combinations with dexamethasone, pomalidomide, elotuzumab, and daratumumab in primary MM cells

Praneeth Reddy Sudalagunta, Mark B. Meads, Rafael Renatino Canevarolo, Maria Coelho Silva, Christopher Cubitt, Gabriel DeAvila, Raghunandan Reddy Alugubelli, Constantine N. Logothetis, Amit Kulkarni, Qi Zhang, Oliver Hampton, Christopher J. Walker, Yosef Landesman, Kenneth Shain, Ariosto Siqueira Silva
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1061.
https://doi.org/10.1158/1538-7445.AM2021-1061
Published: 01 July 2021
View article titled, Abstract 1061: Characterization of synergistic selinexor combinations with dexamethasone, pomalidomide, elotuzumab, and daratumumab in primary MM cells
Journal Articles

Abstract 2482: A portable bioinformatics pipeline for the FDA authorized IMPACT DNAseq assay

Zuojian Tang, Nikhil Kumar, Allan Bolipata, Timothy Song, Cyriac Kandoth, Feng Liu, David Mcmanamon, Oliver Hampton, Nicholas Socci, David Solit
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2482.
https://doi.org/10.1158/1538-7445.AM2019-2482
Published: 01 July 2019
View article titled, Abstract 2482: A portable bioinformatics pipeline for the FDA authorized IMPACT DNAseq assay
Journal Articles

Abstract 2516: A bioinformatics framework for high-sensitivity detection and monitoring of oncogenic gene fusions in plasma cfDNA

Juber Patel, Maysun Hasan, Fanli Meng, Xiaohong Jing, Grittney Tam, Ian Johnson, Youyun Zheng, Chaitanya Bandlamudi, Caitlin Stewart, Helen Won, Oliver Hampton, Alison Schram, Ezra Rosen, Alexander Drilon, Anna Varghese, David Hyman, Dana Tsui, Brian Houck-Loomis, Michael Berger
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2516.
https://doi.org/10.1158/1538-7445.AM2019-2516
Published: 01 July 2019
View article titled, Abstract 2516: A bioinformatics framework for high-sensitivity detection and monitoring of oncogenic gene fusions in plasma cfDNA
Journal Articles

Abstract LB-069: Identification of personalized active agents in pediatric medulloblastoma through high-throughput drug screening in matching pairs of patient derived orthotopic xenograft neurosphere and monolayer cells

Lin Qi, Yuchen Du, Goeun Bae, Mari Mari, Frank Braun, Holly Lindsay, Huiyuan Zhang, Sibo Zhao, Sarah Injac, Patricia Baxter, Jack Su, Michael Mancini, Oliver Hampton, William Parsons, Mural Chintagumpala, Clifford Stephan, Peter Davies, Xiaonan Li
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-069.
https://doi.org/10.1158/1538-7445.AM2018-LB-069
Published: 01 July 2018
View article titled, Abstract LB-069: Identification of personalized active agents in pediatric medulloblastoma through high-throughput drug screening in matching pairs of patient derived orthotopic xenograft neurosphere and monolayer cells
Journal Articles

Abstract 5240: Functional and therapeutic significance of ESR1 gene fusions in breast cancer

Jonathan T. Lei, Jieya Shao, Jin Zhang, Michael Iglesia, Doug W. Chan, Jin Cao, Meenakshi Anurag, Purba Singh, Xiaping He, Yoshimasa Kosaka, Ryoichi Matsunuma, Robert Crowder, Jeremy Hoog, Chanpheng Phommaly, Rodrigo Goncalves, Susana Romalho, Raquel M. Peres, Nindo Punturi, Cheryl Schmidt, Alex Bartram, Eric Jou, W V. Lai, Oliver Hampton, Anna Rogers, Ethan Tobias, Poojan Parikh, Sherri R. Davies, Shunqiang Li, Cynthia X. Ma, Vera Suman, Kelly K. Hunt, Mark A. Watson, Katherine A. Hoadley, E A. Thompson, Xi Chen, Shyam M. Kavuri, Chad J. Creighton, Christopher A. Maher, Charles M. Perou, Svasti Haricharan, Matthew J. Ellis
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5240.
https://doi.org/10.1158/1538-7445.AM2018-5240
Published: 01 July 2018
View article titled, Abstract 5240: Functional and therapeutic significance of <em>ESR1</em> gene fusions in breast cancer
Journal Articles

Abstract 4877: Transcriptome sequencing of pediatric hepatocellular carcinoma reveals genomic events involving APC and TERT

Katherine Haines, Angshumoy Roy, Stephen Sarabia, Linghua Wang, Pavel Sumazin, Kyle Covington, Harsha Doddapaneni, Oliver Hampton, Donna M. Muzny, Dolores Lopez-Terrada, David A. Wheeler, Sharon E. Plon, D. Williams Parsons
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4877.
https://doi.org/10.1158/1538-7445.AM2017-4877
Published: 01 July 2017
View article titled, Abstract 4877: Transcriptome sequencing of pediatric hepatocellular carcinoma reveals genomic events involving <em>APC</em> and <em>TERT</em>
Journal Articles

Abstract 1033: Estrogen receptor gene fusions drive endocrine therapy resistance in estrogen receptor positive breast cancer

Jonathan T. Lei, Jieya Shao, Jin Zhang, Michael Iglesia, Doug W. Chan, Ryoichi Matsunuma, Xiaping He, Purba Singh, Yoshimasa Kosaka, Robert Crowder, Svasti Haricharan, Shyam Kavuri, Jeremy Hoog, Chanpheng Phommaly, Rodrigo Goncalves, Susana Romalho, Wei-Chu Lai, Oliver Hampton, Anna Rogers, Ethan Tobias, Poojan Parikh, Sherri Davies, Cynthia Ma, Vera Suman, Kelly Hunt, Mark Watson, Katherine A. Hoadley, Aubrey Thompson, Charles Perou, Chad J. Creighton, Chris Maher, Matthew J. Ellis
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1033.
https://doi.org/10.1158/1538-7445.AM2017-1033
Published: 01 July 2017
View article titled, Abstract 1033: Estrogen receptor gene fusions drive endocrine therapy resistance in estrogen receptor positive breast cancer
Journal Articles

Abstract 4214: Identification of personalized active agents in pediatric gliomas through high-throughput drug screening in matching pairs of patient derived orthotopic xenograft (PDOX) neurosphere and monolayer cells

Lin Qi, Yuchen Du, Mari Kogiso, Goeun Bae, Frank Braun, Holly Lindsay, Huiyuan Zhang, Sibo Zhao, Sarah Injac, Patricia Baxter, Jack Su, Michael Mancini, Oliver Hampton, William Parsons, Murali Chintagumpala, Clifford Stephan, Peter Davies, Xiao-Nan Li, Xiao-Nan Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4214.
https://doi.org/10.1158/1538-7445.AM2017-4214
Published: 01 July 2017
View article titled, Abstract 4214: Identification of personalized active agents in pediatric gliomas through high-throughput drug screening in matching pairs of patient derived orthotopic xenograft (PDOX) neurosphere and monolayer cells
Journal Articles

Abstract 484: Fidelity of subclonal representation in human neuroblastoma-derived cell line and patient-derived xenograft models: A report from the NCI-TARGET project

Maya Schonbach, Arnavaz Danesh, Jeff Bruce, Tito Woodburn, Tanja Davidsen, Leandro Hermida, Patee Gesuwan, Jaime Guidry Auvil, Oliver Hampton, David Wheeler, Julie Gastier-Foster, Malcolm Smith, Daniela Gerhard, John M. Maris, Patrick Reynolds, Trevor J. Pugh
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 484.
https://doi.org/10.1158/1538-7445.AM2015-484
Published: 01 August 2015
View article titled, Abstract 484: Fidelity of subclonal representation in human neuroblastoma-derived cell line and patient-derived xenograft models: A report from the NCI-TARGET project
Journal Articles

Abstract 4267: Integrated genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups

Dolores H. Lopez-Terrada, Pavel Sumazin, Yidong Chen, Lisa Trevino, Stephen Sarabia, Oliver Hampton, Kayuri Patel, Toni-Ann Mistretta, Barry Zorman, Sarah Comerford, David Wheeler, Murali Chintagumpala, Rebecka M. Meyers, Milton J. Finegold, Gail Tomlinson, Donald W. Parsons
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4267.
https://doi.org/10.1158/1538-7445.AM2015-4267
Published: 01 August 2015
View article titled, Abstract 4267: Integrated genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups
Journal Articles

Basepair-level map of chromosomal aberrations in the MCF-7 breast cancer cell line yields insights into evolution of a cancer genome

Oliver Hampton, Petra Den Hollander, David Delgado, Ronald Harris, Jian Li, Adrian Lee, Aleksandar Milosavljevic
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4332.
Published: 01 May 2008
View article titled, Basepair-level map of chromosomal aberrations in the MCF-7 breast cancer cell line yields insights into evolution of a cancer genome