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Ofer Mandelboim
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Journal Articles

Abstract 7539: First-in-class anti-PVR mAb NTX1088 advancing through Phase I: Safe and potent in restoring DNAM1 expression to enhance antitumor immunity

Anas Atieh, Akram Obeidat, Alon Vitenshtein, Guy Cinamon, Keren Paz, Tihana Roviš, Paola Brilc, Ofer Mandelboim, Stipan Jonjic, Pini Tsukerman
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7539.
https://doi.org/10.1158/1538-7445.AM2024-7539
Published: 22 March 2024
View article titled, Abstract 7539: First-in-class anti-PVR mAb NTX1088 advancing through Phase I: Safe and potent in restoring DNAM1 expression to enhance antitumor immunity
Journal Articles

Abstract 5893: Suppression of anti-tumor immunity by the Fusobacterium nucleatum protease fusolisin

Amjad Shhadeh, Liat Dassa, Jamal Fahoum, Nicole Haj, Reuven Wiener, Ofer Mandelboim, Gilad Bachrach
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5893.
https://doi.org/10.1158/1538-7445.AM2023-5893
Published: 04 April 2023
View article titled, Abstract 5893: Suppression of anti-tumor immunity by the <em>Fusobacterium nucleatum</em> protease fusolisin
Journal Articles

Abstract 6657: Phase I trial of first-in-class anti-PVR mAb NTX1088: Restoration of DNAM1 expression as MOA for enhanced antitumor immunity

Anas Atieh, Akram Obiedat, Alon Vitenshtein, Guy Cinamon, Keren Paz, Tihana lenac, Paola Kucan, Marija Mazor, Ofer Mandelboim, Stipan Jonji, Pini Tsukerman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6657.
https://doi.org/10.1158/1538-7445.AM2023-6657
Published: 04 April 2023
View article titled, Abstract 6657: Phase I trial of first-in-class anti-PVR mAb NTX1088: Restoration of DNAM1 expression as MOA for enhanced antitumor immunity
Journal Articles

Abstract 3436: Novel multifunctional tetravalent CD38 NKp46 FLEX NK࣪ engagers actively target and kill multiple myeloma cells

Liang Lin, Hao-Ming Chang, Cecilia Nakid, Stanley Frankel, Dennis Wu, Jean Kadouche, Daniel Teper, Ofer Mandelboim, Jean-Christophe Bories, Antonio Arulanandam, Wei Li
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3436.
https://doi.org/10.1158/1538-7445.AM2022-3436
Published: 15 June 2022
View article titled, Abstract 3436: Novel multifunctional tetravalent CD38 NKp46 FLEX NK࣪ engagers actively target and kill multiple myeloma cells
Journal Articles

Abstract 5534: NTX-1088, a first-in-class anti-PVR mAb mediates DNAM1-dependent antitumor immunity

Akram Obiedat, Anas Atieh, Guy Cinamon, Keren Paz, Paola Kucan Brilc, Lea Hirsl, Tihana Lenac Roviš, Ofer Mandelboim, Stipan Jonjic, Pini Tsukerman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5534.
https://doi.org/10.1158/1538-7445.AM2022-5534
Published: 15 June 2022
View article titled, Abstract 5534: NTX-1088, a first-in-class anti-PVR mAb mediates DNAM1-dependent antitumor immunity
Journal Articles

Abstract 2752: Preclinical characterization of FLEX-NK࣪ tetravalent NKp46 engager directed against GPC3 (CYT-303) alone or in combination with iPSC derived Natural Killer cells (iNKs) against hepatocellular carcinoma (HCC)

Antonio Arulanandam, Liang Lin, Hao-Ming Chang, David Zou, Melissa Triggiano, Nejmi Dilmac, Yinan Wang, Shira Kahlon, Stanley Frankel, Jean Kadouche, Daniel Teper, Ofer Mandelboim, Wei Li
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2752.
https://doi.org/10.1158/1538-7445.AM2022-2752
Published: 15 June 2022
View article titled, Abstract 2752: Preclinical characterization of FLEX-NK࣪ tetravalent NKp46 engager directed against GPC3 (CYT-303) alone or in combination with iPSC derived Natural Killer cells (iNKs) against hepatocellular carcinoma (HCC)
Journal Articles

MiR-10b Downregulates the Stress-Induced Cell Surface Molecule MICB, a Critical Ligand for Cancer Cell Recognition by Natural Killer Cells

Pinchas Tsukerman, Noam Stern-Ginossar, Chamutal Gur, Ariella Glasner, Daphna Nachmani, Yoav Bauman, Rachel Yamin, Alon Vitenshtein, Noah Stanietsky, Tomer Bar-Mag, Dikla Lankry, Ofer Mandelboim
Journal: Cancer Research
Cancer Res (2012) 72 (21): 5463–5472.
https://doi.org/10.1158/0008-5472.CAN-11-2671
Published: 31 October 2012
View article titled, MiR-10b Downregulates the Stress-Induced Cell Surface Molecule MICB, a Critical Ligand for Cancer Cell Recognition by Natural Killer Cells
Open the PDF for MiR-10b Downregulates the Stress-Induced Cell Surface Molecule MICB, a Critical Ligand for Cancer Cell Recognition by Natural Killer Cells in another window
Includes: Supplementary data
Journal Articles

Caspase-Mediated Cleavage Converts Livin from an Antiapoptotic to a Proapoptotic Factor: Implications for Drug-Resistant Melanoma

Boaz Nachmias, Yaqoub Ashhab, Vered Bucholtz, Olga Drize, Luna Kadouri, Michal Lotem, Tamar Peretz, Ofer Mandelboim, Dina Ben-Yehuda
Journal: Cancer Research
Cancer Res (2003) 63 (19): 6340–6349.
Published: 14 October 2003
View article titled, Caspase-Mediated Cleavage Converts Livin from an Antiapoptotic to a Proapoptotic Factor: <subtitle>Implications for Drug-Resistant Melanoma</subtitle>
Open the PDF for Caspase-Mediated Cleavage Converts Livin from an Antiapoptotic to a Proapoptotic Factor: <subtitle>Implications for Drug-Resistant Melanoma</subtitle> in another window