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Nozomi Tomimatsu
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Journal Articles

Abstract PO4-28-08: Unraveling the Role of BRCA1-BARD1 E3 Ubiquitin Ligase in DNA Repair: A Promise for Enhanced Chemotherapy Outcomes

Wenjing Li, Meiling Wang, Nozomi Tomimatsu, Jae-Hoon Ji, Salvador Alejo, Gangadhara R. Sareddy, Sandeep Burma, Rachel Klevit, Weixing Zhao
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-28-08.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-28-08
Published: 02 May 2024
View article titled, Abstract PO4-28-08: Unraveling the Role of BRCA1-BARD1 E3 Ubiquitin Ligase in DNA Repair: A Promise for Enhanced Chemotherapy Outcomes
Journal Articles

Abstract A035: Radiation-induced senescence as a driver of glioblastoma recurrence

Ben R. Jordan, Nozomi Tomimatsu, Luis Macedo Di Cristofaro, Suman Kanji, Bipasha Mukherjee, Sandeep Burma
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_1): A035.
https://doi.org/10.1158/1538-7445.BRAIN23-A035
Published: 04 March 2024
View article titled, Abstract A035: Radiation-induced senescence as a driver of glioblastoma recurrence
Journal Articles

Abstract PR001: DNA damage-induced senescence as a driver of glioblastoma recurrence

Sandeep Burma, Nozomi Tomimatsu, Luis Cristofaro, Suman Kanji, Benjamin Jordan, Bipasha Mukherjee
Journal: Cancer Research
Cancer Res (2024) 84 (1_Supplement): PR001.
https://doi.org/10.1158/1538-7445.DNAREPAIR24-PR001
Published: 09 January 2024
View article titled, Abstract PR001: DNA damage-induced senescence as a driver of glioblastoma recurrence
Journal Articles

Abstract A009: DNA damage-induced senescence as a driver of glioblastoma recurrence

Sandeep Burma, Nozomi Tomimatsu, Luis Cristofaro, Suman Kanji, Benjamin Jordan, Bipasha Mukherjee
Journal: Cancer Research
Cancer Res (2024) 84 (1_Supplement): A009.
https://doi.org/10.1158/1538-7445.DNAREPAIR24-A009
Published: 09 January 2024
View article titled, Abstract A009: DNA damage-induced senescence as a driver of glioblastoma recurrence
Journal Articles

Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence

Eliot Fletcher-Sananikone, Suman Kanji, Nozomi Tomimatsu, Luis Fernando Macedo Di Cristofaro, Rahul K. Kollipara, Debabrata Saha, John R. Floyd, Patrick Sung, Robert Hromas, Terry C. Burns, Ralf Kittler, Amyn A. Habib, Bipasha Mukherjee, Sandeep Burma
Journal: Cancer Research
Cancer Res (2021) 81 (23): 5935–5947.
https://doi.org/10.1158/0008-5472.CAN-21-0752
Published: 01 December 2021
View article titled, Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence
Open the PDF for Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence in another window
Includes: Supplementary data
Journal Articles

Abstract 2006: Targeting AXL kinase with TP-0903 successfully reverses the mesenchymal phenotype and extends survival in preclinical models of advanced ovarian cancer

Nozomi Tomimatsu, Ken Fujimura, Yuta Matsumura, Hiroki Umehara, Lars Mouritsen, Steven L. Warner, David J. Bearss
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2006.
https://doi.org/10.1158/1538-7445.AM2019-2006
Published: 01 July 2019
View article titled, Abstract 2006: Targeting AXL kinase with TP-0903 successfully reverses the mesenchymal phenotype and extends survival in preclinical models of advanced ovarian cancer
Journal Articles

INT6/EIF3E Controls the RNF8-Dependent Ubiquitylation Pathway and Facilitates DNA Double-Strand Break Repair in Human Cells

Christelle Morris, Nozomi Tomimatsu, Sandeep Burma, Pierre Jalinot
Journal: Cancer Research
Cancer Res (2016) 76 (20): 6054–6065.
https://doi.org/10.1158/0008-5472.CAN-16-0723
Published: 13 October 2016
View article titled, INT6/EIF3E Controls the RNF8-Dependent Ubiquitylation Pathway and Facilitates DNA Double-Strand Break Repair in Human Cells
Open the PDF for INT6/EIF3E Controls the RNF8-Dependent Ubiquitylation Pathway and Facilitates DNA Double-Strand Break Repair in Human Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 523: Activating mutations in EGFR abrogate hypoxia-associated radiation resistance in non-small cell lung cancer

Mohammad Saki, Haruhiko Makino, Nozomi Tomimatsu, Lianghao Ding, Michael D. Story, Sandeep Burma, Chaitanya Nirodi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 523.
https://doi.org/10.1158/1538-7445.AM2016-523
Published: 15 July 2016
View article titled, Abstract 523: Activating mutations in EGFR abrogate hypoxia-associated radiation resistance in non-small cell lung cancer
Journal Articles

Abstract LB-359: Inhibition of DNA repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a novel radiosensitization strategy for glioblastoma.

Carlos Gil Del Alcazar, Molly Gillam, Nozomi Tomimatsu, Xiaohuan Gao, Bipasha Mukherjee, Sandeep Burma
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-359.
https://doi.org/10.1158/1538-7445.AM2013-LB-359
Published: 15 April 2013
View article titled, Abstract LB-359: Inhibition of DNA repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a novel radiosensitization strategy for glioblastoma.
Journal Articles

INT6/EIF3E Interacts with ATM and Is Required for Proper Execution of the DNA Damage Response in Human Cells

Christelle Morris, Nozomi Tomimatsu, Derek J. Richard, David Cluet, Sandeep Burma, Kum Kum Khanna, Pierre Jalinot
Journal: Cancer Research
Cancer Res (2012) 72 (8): 2006–2016.
https://doi.org/10.1158/0008-5472.CAN-11-2562
Published: 16 April 2012
View article titled, INT6/EIF3E Interacts with ATM and Is Required for Proper Execution of the DNA Damage Response in Human Cells
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Includes: Supplementary data
Journal Articles

Abstract 3745: The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKcs-mediated DNA damage responses

Bipasha Mukherjee, Nozomi Tomimatsu, Kaushik Amancherla, Cristel Camacho, Sandeep Burma
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3745.
https://doi.org/10.1158/1538-7445.AM2012-3745
Published: 15 April 2012
View article titled, Abstract 3745: The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKcs-mediated DNA damage responses
Journal Articles

PTEN Loss Compromises Homologous Recombination Repair in Astrocytes: Implications for Glioblastoma Therapy with Temozolomide or Poly(ADP-Ribose) Polymerase Inhibitors

Brian McEllin, Cristel V. Camacho, Bipasha Mukherjee, Brandon Hahm, Nozomi Tomimatsu, Robert M. Bachoo, Sandeep Burma
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5457–5464.
https://doi.org/10.1158/0008-5472.CAN-09-4295
Published: 30 June 2010
View article titled, PTEN Loss Compromises Homologous Recombination Repair in Astrocytes: Implications for Glioblastoma Therapy with Temozolomide or Poly(ADP-Ribose) Polymerase Inhibitors
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Includes: Supplementary data
Journal Articles

EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in Glioblastoma

Bipasha Mukherjee, Brian McEllin, Cristel V. Camacho, Nozomi Tomimatsu, Shyam Sirasanagandala, Suraj Nannepaga, Kimmo J. Hatanpaa, Bruce Mickey, Christopher Madden, Elizabeth Maher, David A. Boothman, Frank Furnari, Webster K. Cavenee, Robert M. Bachoo, Sandeep Burma
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4252–4259.
https://doi.org/10.1158/0008-5472.CAN-08-4853
Published: 15 May 2009
View article titled, EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in Glioblastoma
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