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Abstract 349: Oncolytic reovirus variants induce direct oncolysis in human prostate cancer

Arjanneke F. van de Merbel, Geertje van der Horst, Maaike H. van der Mark, Diana J. van den Wollenberg, Jack A. Schalken, Anne Collins, Norman J. Maitland, Rob C. Hoeben, Gabri van der Pluijm

Cancer Res (2019) 79 (13_Supplement): 349.

DOI: https://doi.org/10.1158/1538-7445.AM2019-349

Published: 01 July 2019

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Journal Articles

Abstract A040: Targeting the prostate cancer stem cell niche with the STAT3 inhibitor galiellalactone

Giacomo Canesin, Anne T. Collins, Rebecka Hellsten, Norman J. Maitland, Anders Bjartell

Cancer Res (2018) 78 (16_Supplement): A040.

DOI: https://doi.org/10.1158/1538-7445.PRCA2017-A040

Published: 14 August 2018

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Journal Articles

Abstract 1662: Synthesis and biologic evaluation of diethylbenzaldehyde analogues to probe functional activity of aldehyde dehydrogenase activity in cancer

Ali Ibrahim, Maria Sadiq, Daniela Presa, Ioannis Ntafoulis, Ahmad Alkawi, Fiona Frame, Norman J. Maitland, Zoe Cournia, Paul M. Loadman, Jan Moreb, Klaus Pors

Cancer Res (2018) 78 (13_Supplement): 1662.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1662

Published: 01 July 2018

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Journal Articles

Abstract 3900: STAT3 inhibition with Galiellalactone effectively targets the prostate cancer stem-like cell population

Giacomo Canesin, Anne T. Collins, Rebecka Hellsten, Norman J. Maitland, Anders Bjartell

Cancer Res (2017) 77 (13_Supplement): 3900.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3900

Published: 01 July 2017

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Journal Articles

Abstract 1900: Understanding the biological role of latexin in the normal and malignant prostate

Robert I. Seed, Alberto J. Taurozzi, Giovanna Nappo, Holger H. Erb, Anne Collins, Norman J. Maitland, Fiona Frame

Cancer Res (2017) 77 (13_Supplement): 1900.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1900

Published: 01 July 2017

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Journal Articles

Abstract 970: Probing the expression and function of aldehyde dehydrogenases in prostate cancer using ALDH-affinic compounds and siRNA

Maria Sadiq, Ali I. Ibrahim, Fiona Frame, Simon J. Allison, Mark Sutherland, Roger M. Phillips, Norman J. Maitland, Klaus Pors

Cancer Res (2017) 77 (13_Supplement): 970.

DOI: https://doi.org/10.1158/1538-7445.AM2017-970

Published: 01 July 2017

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Journal Articles

Abstract 5102: TRXE-009-1 has pan-acting anticancer activity and potently inhibits colony formation of prostate cancer epithelial cell explants

Eleanor I. Ager, Dominika Butler, Alex Stevenson, Eiffe Eiffe, Andrew Heaton, Brian Gabrielli, Norman J. Maitland, David Brown

Cancer Res (2017) 77 (13_Supplement): 5102.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5102

Published: 01 July 2017

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Journal Articles

Abstract 4093: The impact of the prostate cancer microenvironment on the expression and regulation of aldehyde dehydrogenases

Maria Sadiq, Simon J. Allison, Fiona Frame, Mark Sutherland, Roger M. Phillips, Norman J. Maitland, Klaus Pors

Cancer Res (2016) 76 (14_Supplement): 4093.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4093

Published: 15 July 2016

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Journal Articles

An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells

Cancer Res (2016) 76 (9): 2637–2651.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-2116

Published: 01 May 2016

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Includes: Supplementary data

Journal Articles

Cyclin A1 and P450 Aromatase Promote Metastatic Homing and Growth of Stem-like Prostate Cancer Cells in the Bone Marrow

Regina Miftakhova, Andreas Hedblom, Julius Semenas, Brian Robinson, Athanasios Simoulis, Johan Malm, Albert Rizvanov, David M. Heery, Nigel P. Mongan, Norman J. Maitland, Cinzia Allegrucci, Jenny L. Persson

Cancer Res (2016) 76 (8): 2453–2464.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-2340

Published: 14 April 2016

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Includes: Supplementary data

Journal Articles

Abstract 3: Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy

Frédéric R. Santer, Holger H.H. Erb, Su Jung Oh, Florian Handle, Gertrud E. Feiersinger, Birgit Luef, Huajie Bu, Georg Schäfer, Christian Ploner, Martina Egger, Jayant K. Rane, Norman J. Maitland, Helmut Klocker, Iris E. Eder, Zoran Culig

Cancer Res (2015) 75 (15_Supplement): 3.

DOI: https://doi.org/10.1158/1538-7445.AM2015-3

Published: 01 August 2015

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Journal Articles

Abstract 3053: Epigenetic control of cell phenotypes in the stem cell compartments of human prostate and prostate cancer: Implications for enhancement of prostate cancer therapies

Norman J. Maitland, Davide Pellacani, Jayant K. Rane, Fiona M. Frame, Anne T. Collins

Cancer Res (2014) 74 (19_Supplement): 3053.

DOI: https://doi.org/10.1158/1538-7445.AM2014-3053

Published: 01 October 2014

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Journal Articles

Abstract B25: DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation

Davide Pellacani, Dimitra Kestoras, Alastair P. Droop, Fiona M. Frame, Paul A. Berry, Mitchell G. Lawrence, Michael J. Stower, Matthew S. Simms, Vincent M. Mann, Anne T. Collins, Gail P. Risbridger, Norman J. Maitland

Cancer Res (2013) 73 (13_Supplement): B25.

DOI: https://doi.org/10.1158/1538-7445.CEC13-B25

Published: 13 May 2014

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Journal Articles

JAK-STAT Blockade Inhibits Tumor Initiation and Clonogenic Recovery of Prostate Cancer Stem-like Cells

Paula Kroon, Paul A. Berry, Michael J. Stower, Greta Rodrigues, Vincent M. Mann, Matthew Simms, Deepak Bhasin, Somsundaram Chettiar, Chenglong Li, Pui-Kai Li, Norman J. Maitland, Anne T. Collins

Cancer Res (2013) 73 (16): 5288–5298.

DOI: https://doi.org/10.1158/0008-5472.CAN-13-0874

Published: 13 August 2013

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Includes: Supplementary data

Journal Articles

Abstract 1726: Androgenic regulation of the anti-apoptotic Bcl-2 family member Mcl-1 in prostate cancer cells.

Frédéric R. Santer, Holger H. Erb, Birgit Luef, Florian Handle, Su Jung Oh, Susanne Lobenwein, Christian Ploner, Jayant Rane, Anne T. Collins, Norman J. Maitland, Zoran Culig

Cancer Res (2013) 73 (8_Supplement): 1726.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1726

Published: 15 April 2013

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Journal Articles

Abstract 5198: Elucidation of dynamic prostate epithelial hierarchy: Insights into transcriptional and epigenetic regulatory mechanisms

Jayant K. Rane, Davide Pellacani, Alastair P. Droop, Antti Ylipää, Michael J. Stower, Matthew S. Simms, Vincet M. Mann, Tapio Visakorpi, Anne T. Collins, Norman J. Maitland

Cancer Res (2012) 72 (8_Supplement): 5198.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5198

Published: 15 April 2012

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Journal Articles

Abstract 5209: Prostate cancer progenitor cells have distinct DNA methylation profile which changes upon differentiation

Davide Pellacani, Dimitra Kestoras, Alastair P. Droop, Katherine M. Wilson, Euan S. Polson, Stefanie Hager, Fiona M. Frame, Paul A. Berry, Michael J. Stower, Matthew S. Simms, Vincent M. Mann, Anne T. Collins, Norman J. Maitland

Cancer Res (2012) 72 (8_Supplement): 5209.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5209

Published: 15 April 2012

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Journal Articles

Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors

Munitta Muthana, Athina Giannoudis, Simon D. Scott, Hsin-Yu Fang, Seth B. Coffelt, Fiona J. Morrow, Craig Murdoch, Julian Burton, Neil Cross, Bernard Burke, Roshna Mistry, Freddie Hamdy, Nicola J. Brown, Lindsay Georgopoulos, Peter Hoskin, Magnus Essand, Claire E. Lewis, Norman J. Maitland

Cancer Res (2011) 71 (5): 1805–1815.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-2349

Published: 01 March 2011

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Includes: Supplementary data

Journal Articles

Altered Expression of Neurotensin Receptors Is Associated with the Differentiation State of Prostate Cancer

Stephanie L. Swift, Julie E. Burns, Norman J. Maitland

Cancer Res (2010) 70 (1): 347–356.

DOI: https://doi.org/10.1158/0008-5472.CAN-09-1252

Published: 04 January 2010

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Includes: Supplementary data

Journal Articles

Metalloproteinase expression in stromal and epithelial compartments can influence prostate cancer cell invasion

Badar A. Usmani, Anthony J. Turner, Norman J. Maitland, Louise A. Dawson

Cancer Res (2006) 66 (8_Supplement): 775.

Published: 15 April 2006

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NARROW

Abstract 349: Oncolytic reovirus variants induce direct oncolysis in human prostate cancer

Abstract A040: Targeting the prostate cancer stem cell niche with the STAT3 inhibitor galiellalactone

Abstract 1662: Synthesis and biologic evaluation of diethylbenzaldehyde analogues to probe functional activity of aldehyde dehydrogenase activity in cancer

Abstract 3900: STAT3 inhibition with Galiellalactone effectively targets the prostate cancer stem-like cell population

Abstract 1900: Understanding the biological role of latexin in the normal and malignant prostate

Abstract 970: Probing the expression and function of aldehyde dehydrogenases in prostate cancer using ALDH-affinic compounds and siRNA

Abstract 5102: TRXE-009-1 has pan-acting anticancer activity and potently inhibits colony formation of prostate cancer epithelial cell explants

Abstract 4093: The impact of the prostate cancer microenvironment on the expression and regulation of aldehyde dehydrogenases

An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells

Cyclin A1 and P450 Aromatase Promote Metastatic Homing and Growth of Stem-like Prostate Cancer Cells in the Bone Marrow

Abstract 3: Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy

Abstract 3053: Epigenetic control of cell phenotypes in the stem cell compartments of human prostate and prostate cancer: Implications for enhancement of prostate cancer therapies

Abstract B25: DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation

JAK-STAT Blockade Inhibits Tumor Initiation and Clonogenic Recovery of Prostate Cancer Stem-like Cells

Abstract 1726: Androgenic regulation of the anti-apoptotic Bcl-2 family member Mcl-1 in prostate cancer cells.

Abstract 5198: Elucidation of dynamic prostate epithelial hierarchy: Insights into transcriptional and epigenetic regulatory mechanisms

Abstract 5209: Prostate cancer progenitor cells have distinct DNA methylation profile which changes upon differentiation

Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors

Altered Expression of Neurotensin Receptors Is Associated with the Differentiation State of Prostate Cancer

Metalloproteinase expression in stromal and epithelial compartments can influence prostate cancer cell invasion

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