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Nobuyuki Ito
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Journal Articles

Immunohistochemical Demonstration of Carcinogen-DNA Adducts in Tissues of Rats Given 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): Detection in Paraffin-embedded Sections and Tissue Distribution

Free
Satoru Takahashi, Seiko Tamano, Masao Hirose, Naoya Kimoto, Yoshihisa Ikeda, Michihisa Sakakibara, Mariko Tada, Fred F. Kadlubar, Nobuyuki Ito, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (1998) 58 (19): 4307–4313.
Published: 01 October 1998
View articletitled, Immunohistochemical Demonstration of Carcinogen-DNA Adducts in Tissues of Rats Given 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): Detection in Paraffin-embedded Sections and Tissue Distribution
Open the PDF for Immunohistochemical Demonstration of Carcinogen-DNA Adducts in Tissues of Rats Given 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): Detection in Paraffin-embedded Sections and Tissue Distribution in another window
Journal Articles

The Prostate: A Target for Carcinogenicity of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Derived from Cooked Foods

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Tomoyuki Shirai, Masashi Sano, Seiko Tamano, Satoru Takahashi, Masao Hirose, Mitsuru Futakuchi, Ryohei Hasegawa, Katsumi Imaida, Ken-ichiro Matsumoto, Keiji Wakabayashi, Takashi Sugimura, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1997) 57 (2): 195–198.
Published: 01 January 1997
View articletitled, The Prostate: A Target for Carcinogenicity of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Derived from Cooked Foods
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Journal Articles

Chemoprevention by Dehydroepiandrosterone and Indomethacin in a Rat Multiorgan Carcinogenesis Model

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Masa-Aki Shibata, Ryohei Hasegawa, Katsumi Imaida, Akihiro Hagiwara, Kumiko Ogawa, Masao Hirose, Nobuyuki Ito, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (1995) 55 (21): 4870–4874.
Published: 01 November 1995
View articletitled, Chemoprevention by Dehydroepiandrosterone and Indomethacin in a Rat Multiorgan Carcinogenesis Model
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Journal Articles

Increased Risk of Mammary Carcinoma Development following Transplacental and Trans-Breast Milk Exposure to a Food-derived Carcinogen, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in Sprague-Dawley Rats

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Ryohei Hasegawa, Juki Kimura, Makoto Yaono, Satoru Takahashi, Toshio Kato, Mitsuru Futakuchi, Masato Fukutake, Kazuo Fukutome, Keiji Wakabayashi, Takashi Sugimura, Nobuyuki Ito, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (1995) 55 (19): 4333–4338.
Published: 01 October 1995
View articletitled, Increased Risk of Mammary Carcinoma Development following Transplacental and Trans-Breast Milk Exposure to a Food-derived Carcinogen, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in Sprague-Dawley Rats
Open the PDF for Increased Risk of Mammary Carcinoma Development following Transplacental and Trans-Breast Milk Exposure to a Food-derived Carcinogen, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in Sprague-Dawley Rats in another window
Journal Articles

Effects of Sodium Nitrite and Catechol, 3-Methoxycatechol, or Butylated Hydroxyanisole in Combination in a Rat Multiorgan Carcinogenesis Model

Free
Masao Hirose, Hikaru Tanaka, Satoru Takahashi, Mitsuru Futakuchi, Shoji Fukushima, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1993) 53 (1): 32–37.
Published: 01 January 1993
View articletitled, Effects of Sodium Nitrite and Catechol, 3-Methoxycatechol, or Butylated Hydroxyanisole in Combination in a Rat Multiorgan Carcinogenesis Model
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Journal Articles

Multistage Carcinogenesis: The Twenty-Second International Symposium of the Princess Takamatsu Cancer Research Fund

Free
Curtis C. Harris, Setsuo Hirohashi, Nobuyuki Ito, Henry C. Pitot, Takashi Sugimura, Masaaki Terada, Jun Yokota
Journal: Cancer Research
Cancer Res (1992) 52 (17): 4837–4840.
Published: 01 September 1992
View articletitled, Multistage Carcinogenesis: The Twenty-Second International Symposium of the Princess Takamatsu Cancer Research Fund
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Journal Articles

Reversibility of Catechol-induced Rat Glandular Stomach Lesions

Free
Masao Hirose, Shigetsugu Wada, Shuji Yamaguchi, Atsuko Masuda, Shuzo Okazaki, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1992) 52 (4): 787–790.
Published: 01 February 1992
View articletitled, Reversibility of Catechol-induced Rat Glandular Stomach Lesions
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Journal Articles

Forestomach and Kidney Carcinogenicity of Caffeic Acid in F344 Rats and C57BL/6N × C3H/HeN F1 Mice

Free
Akihiro Hagiwara, Masao Hirose, Satoru Takahashi, Kumiko Ogawa, Tomoyuki Shirai, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1991) 51 (20): 5655–5660.
Published: 01 October 1991
View articletitled, Forestomach and Kidney Carcinogenicity of Caffeic Acid in F344 Rats and C57BL/6N × C3H/HeN F1 Mice
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Journal Articles

Elevated Levels of Transforming Growth Factor β Messenger RNA and Its Polypeptide in Human Hepatocellular Carcinoma

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Nobuyuki Ito, Sumio Kawata, Shinji Tamura, Kenji Takaishi, Yasuhiro Shirai, Shinichi Kiso, Iwao Yabuuchi, Yasuo Matsuda, Minoru Nishioka, Seiichiro Tarui
Journal: Cancer Research
Cancer Res (1991) 51 (15): 4080–4083.
Published: 01 August 1991
View articletitled, Elevated Levels of Transforming Growth Factor β Messenger RNA and Its Polypeptide in Human Hepatocellular Carcinoma
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Journal Articles

Induction of Invasive Carcinomas in the Accessory Sex Organs Other Than the Ventral Prostate of Rats Given 3,2′-Dimethyl-4-aminobiphenyl and Testosterone Propionate

Free
Tomoyuki Shirai, Seiko Tamano, Toshio Kato, Shogo Iwasaki, Satoru Takahashi, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1991) 51 (4): 1264–1269.
Published: 01 February 1991
View articletitled, Induction of Invasive Carcinomas in the Accessory Sex Organs Other Than the Ventral Prostate of Rats Given 3,2′-Dimethyl-4-aminobiphenyl and Testosterone Propionate
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Journal Articles

Effects of Phenolic Antioxidants in Low Dose Combination on Forestomach Carcinogenesis in Rats Pretreated with N-Methyl-N′-nitro-N-nitrosoguanidine

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Masao Hirose, Mamoru Mutai, Satoru Takahashi, Mayumi Yamada, Shoji Fukushima, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1991) 51 (3): 824–827.
Published: 01 February 1991
View articletitled, Effects of Phenolic Antioxidants in Low Dose Combination on Forestomach Carcinogenesis in Rats Pretreated with N-Methyl-N′-nitro-N-nitrosoguanidine
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Journal Articles

Rapid Regression of Squamous Cell Hyperplasia and Slow Regression of Basal Cell Hyperplasia in the Forestomach of F344 Rats Treated with N-Methyl-N′-nitro-N-nitrosoguanidine and/or Butylated Hydroxyanisole

Free
Masae Tatematsu, Kumiko Ogawa, Mamoru Mutai, Toyohiko Aoki, Toru Hoshiya, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1991) 51 (1): 318–323.
Published: 01 January 1991
View articletitled, Rapid Regression of Squamous Cell Hyperplasia and Slow Regression of Basal Cell Hyperplasia in the Forestomach of F344 Rats Treated with N-Methyl-N′-nitro-N-nitrosoguanidine and/or Butylated Hydroxyanisole
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Journal Articles

Increase in the Active Form of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase in Human Hepatocellular Carcinoma: Possible Mechanism for Alteration of Cholesterol Biosynthesis

Free
Sumio Kawata, Kenji Takaishi, Toshihiko Nagase, Nobuyuki Ito, Yukihiko Matsuda, Shinji Tamura, Yuji Matsuzawa, Seiichiro Tarui
Journal: Cancer Research
Cancer Res (1990) 50 (11): 3270–3273.
Published: 01 June 1990
View articletitled, Increase in the Active Form of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase in Human Hepatocellular Carcinoma: Possible Mechanism for Alteration of Cholesterol Biosynthesis
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Journal Articles

Modification by Catechol and Resorcinol of Upper Digestive Tract Carcinogenesis in Rats Treated with Methyl-N-amylnitrosamine

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Shuji Yamaguchi, Masao Hirose, Shoji Fukushima, Ryohei Hasegawa, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1989) 49 (21): 6015–6018.
Published: 01 November 1989
View articletitled, Modification by Catechol and Resorcinol of Upper Digestive Tract Carcinogenesis in Rats Treated with Methyl-N-amylnitrosamine
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Journal Articles

Promotion by Dihydroxybenzene Derivatives of N-Methyl-N′-nitro-N-nitrosoguanidine-induced F344 Rat Forestomach and Glandular Stomach Carcinogenesis

Free
Masao Hirose, Shuji Yamaguchi, Shoji Fukushima, Ryohei Hasegawa, Satoshi Takahashi, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1989) 49 (18): 5143–5147.
Published: 01 September 1989
View articletitled, Promotion by Dihydroxybenzene Derivatives of N-Methyl-N′-nitro-N-nitrosoguanidine-induced F344 Rat Forestomach and Glandular Stomach Carcinogenesis
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Journal Articles

Cell Proliferation Induced by Uracil-Calculi and Subsequent Development of Reversible Papillomatosis in the Rat Urinary Bladder

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Tomoyuki Shirai, Shoji Fukushima, Yoshiaki Tagawa, Masanao Okumura, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1989) 49 (2): 378–383.
Published: 01 January 1989
View articletitled, Cell Proliferation Induced by Uracil-Calculi and Subsequent Development of Reversible Papillomatosis in the Rat Urinary Bladder
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Journal Articles

Modification of N-Methyl-N′-nitro-N-nitrosoguanidine-induced Forestomach and Glandular Stomach Carcinogenesis by Phenolic Antioxidants in Rats

Free
Masao Hirosa, Shoji Fukushima, Yasushi Kurata, Hiroyuki Tsuda, Masae Tatematsu, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1988) 48 (18): 5310–5315.
Published: 01 September 1988
View articletitled, Modification of N-Methyl-N′-nitro-N-nitrosoguanidine-induced Forestomach and Glandular Stomach Carcinogenesis by Phenolic Antioxidants in Rats
Open the PDF for Modification of N-Methyl-N′-nitro-N-nitrosoguanidine-induced Forestomach and Glandular Stomach Carcinogenesis by Phenolic Antioxidants in Rats in another window
Journal Articles

Variation in Tumor Yield in the Prostate and Other Target Organs of the Rat in Response to Varied Dosage and Duration of Administration of 3,2′-Dimethyl-4-aminobiphenyl

Free
Nobuyuki Ito, Tomoyuki Shirai, Yoshiaki Tagawa, Atsushi Nakamura, Shoji Fukushima
Journal: Cancer Research
Cancer Res (1988) 48 (16): 4629–4632.
Published: 01 August 1988
View articletitled, Variation in Tumor Yield in the Prostate and Other Target Organs of the Rat in Response to Varied Dosage and Duration of Administration of 3,2′-Dimethyl-4-aminobiphenyl
Open the PDF for Variation in Tumor Yield in the Prostate and Other Target Organs of the Rat in Response to Varied Dosage and Duration of Administration of 3,2′-Dimethyl-4-aminobiphenyl in another window
Journal Articles

Strong Promoting Activity of Reversible Uracil-induced Urolithiasis on Urinary Bladder Carcinogenesis in Rats Initiated with N-Butyl-N-(4-hydroxybutyl)nitrosamine

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Tomoyuki Shirai, Yoshiaki Tagawa, Shoji Fukushima, Katsumi Imaida, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1987) 47 (24_Part_1): 6726–6730.
Published: 15 December 1987
View articletitled, Strong Promoting Activity of Reversible Uracil-induced Urolithiasis on Urinary Bladder Carcinogenesis in Rats Initiated with N-Butyl-N-(4-hydroxybutyl)nitrosamine
Open the PDF for Strong Promoting Activity of Reversible Uracil-induced Urolithiasis on Urinary Bladder Carcinogenesis in Rats Initiated with N-Butyl-N-(4-hydroxybutyl)nitrosamine in another window
Journal Articles

Regression of Simple Hyperplasia and Papillomas and Persistence of Basal Cell Hyperplasia in the Forestomach of F344 Rats Treated with Butylated Hydroxyanisole

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Tsuneo Masui, Makoto Asamoto, Masao Hirose, Shoji Fukushima, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1987) 47 (19): 5171–5174.
Published: 01 October 1987
View articletitled, Regression of Simple Hyperplasia and Papillomas and Persistence of Basal Cell Hyperplasia in the Forestomach of F344 Rats Treated with Butylated Hydroxyanisole
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