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Niramol Savaraj
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Journal Articles

Abstract 3065: Targeting of metabolic reprogramming in lung cancer by utilizing patient-derived organoid tissue for precision medicine

Free
Chunjing Wu, Jonathan D. Nguyen, George Theodore, Estelamari Rodriguez, Sydney Spector, Emily Kim, Taranatee Khan, Pablo Puente, Yujie Wang, Dao M. Nguyen, Cheng-Bang Chen, Diane Lim, Lynn G. Feun, Niramol Savaraj, Medhi Wangpaichitr
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3065.
https://doi.org/10.1158/1538-7445.AM2024-3065
Published: 22 March 2024
View article titled, Abstract 3065: Targeting of metabolic reprogramming in lung cancer by utilizing patient-derived organoid tissue for precision medicine
Journal Articles

Abstract 3840: Can serum exosomal content predict response to immunotherapy in hepatocellular carcinoma

Free
Niramol Savaraj, Pablo Puente, Ying-Ying Li, Chunjing Wu, Jonathan D. Nguyen, Medhi Wangpaichitr, Peter J. Hosein, Lynn G. Feun
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3840.
https://doi.org/10.1158/1538-7445.AM2024-3840
Published: 22 March 2024
View article titled, Abstract 3840: Can serum exosomal content predict response to immunotherapy in hepatocellular carcinoma
Journal Articles

Abstract 5886: Targeting IDO1 and TDO2 is crucial for the modulation of immune effector in platinum resistant non-small cell lung cancer

Free
Sydney Spector, Chunjing Wu, George Theodore, Jonathan Dan Nguyen, Emily Kim, Ashley Garcia, Niramol Savaraj, Diane Lim, Lynn Feun, Medhi Wangpaichitr
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5886.
https://doi.org/10.1158/1538-7445.AM2023-5886
Published: 04 April 2023
View article titled, Abstract 5886: Targeting IDO1 and TDO2 is crucial for the modulation of immune effector in platinum resistant non-small cell lung cancer
Journal Articles

Abstract 4114: Can exosomal cargoes predict checkpoint inhibitor response in melanoma, and can we overcome drug resistance

Free
Pablo Eduardo Puente, Dan Nguyen, Niramol Savaraj, Chunjing Wu, Medhi Wangpaichitr, Stephane Roche, Guangkuan Zhao, Alexis Richaud, Jose Lutzky, Leonel Hernandez Aya, Mecker Moller, Jessica Crystal, Neha Goel, Lynn Feun
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4114.
https://doi.org/10.1158/1538-7445.AM2023-4114
Published: 04 April 2023
View article titled, Abstract 4114: Can exosomal cargoes predict checkpoint inhibitor response in melanoma, and can we overcome drug resistance
Journal Articles

Abstract 2325: Targeting kynurenine pathway using novel IDO/TDO dual inhibitor (AT0174) to modulate tumor microenvironment in platinum resistant non-small cell lung cancer cancer: An immunometabolism compliment markers

Free
Sydney Spector, Chunjing Wu, Dan Nguyen, George Theodore, Ashley Garcia, Lynn Feun, Niramol Savaraj, Medhi Wangpaichitr
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2325.
https://doi.org/10.1158/1538-7445.AM2022-2325
Published: 15 June 2022
View article titled, Abstract 2325: Targeting kynurenine pathway using novel IDO/TDO dual inhibitor (AT0174) to modulate tumor microenvironment in platinum resistant non-small cell lung cancer cancer: An immunometabolism compliment markers
Journal Articles

Abstract 2771: Circulating biomarkers to predict antitumor response to immunotherapy in advanced unresectable hepatoma

Free
Lynn G. Feun, Ying-Ying Li, Chunjing Wu, Medhi Wangpaichitr, Alfred Chicco, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2771.
https://doi.org/10.1158/1538-7445.AM2022-2771
Published: 15 June 2022
View article titled, Abstract 2771: Circulating biomarkers to predict antitumor response to immunotherapy in advanced unresectable hepatoma
Journal Articles

Abstract 988: Targeting immunological and apoptotic cell death to improve therapeutic efficacy in melanoma

Free
Niramol Savaraj, Min You, Ying-Ying Li, Chunjing Wu, Medhi Wangpaichitr, Saurez Miguel, Alfred Chicco, Macus T. Kuo, Lynn G. Feun
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 988.
https://doi.org/10.1158/1538-7445.AM2021-988
Published: 01 July 2021
View article titled, Abstract 988: Targeting immunological and apoptotic cell death to improve therapeutic efficacy in melanoma
Journal Articles

Abstract 4747: Surviving skills in melanoma cells: An important consideration to both targeted and immunological approach in the treatment of melanoma

Free
Niramol Savaraj, Ying-Ying Li, Chunjing Wu, Medhi Wangpaichitr, Seth Spector, Michael Sentome, Lynn G. Feun
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4747.
https://doi.org/10.1158/1538-7445.AM2019-4747
Published: 01 July 2019
View article titled, Abstract 4747: Surviving skills in melanoma cells: An important consideration to both targeted and immunological approach in the treatment of melanoma
Journal Articles

Abstract 4361: Kynurenine - Aryl hydrocarbon receptor axis: A crucial modulator of immunometabolism in cisplatin resistant lung cancer

Free
Medhi Wangpaichitr, Dan JM Nguyen, Ying-Ying Li, Chunjing Wu, Lynn G. Feun, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4361.
https://doi.org/10.1158/1538-7445.AM2019-4361
Published: 01 July 2019
View article titled, Abstract 4361: Kynurenine - Aryl hydrocarbon receptor axis: A crucial modulator of immunometabolism in cisplatin resistant lung cancer
Journal Articles

Abstract 5478: Targeting kynurenine pathway for the treatment of cisplatin-resistant lung cancer

Free
Medhi Wangpaichitr, Chunjing Wu, Dan JM Nguyen, Ying-Ying Li, Lynn G. Feun, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5478.
https://doi.org/10.1158/1538-7445.AM2018-5478
Published: 01 July 2018
View article titled, Abstract 5478: Targeting kynurenine pathway for the treatment of cisplatin-resistant lung cancer
Journal Articles

Abstract 3642: Relationship of argininosuccinate synthetase (ASS) and PD-L1 expression in arginine enriched or depleted environment in melanoma

Free
Chunjing Wu, Ying-Ying Li, Medhi Wangpaichitr, Lynn G. Feun, Macus T. Kuo, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3642.
https://doi.org/10.1158/1538-7445.AM2018-3642
Published: 01 July 2018
View article titled, Abstract 3642: Relationship of argininosuccinate synthetase (ASS) and PD-L1 expression in arginine enriched or depleted environment in melanoma
Journal Articles

Abstract 4404: Novel approach to circumvent cisplatin resistant lung cancer by targeting metabolism

Free
Medhi Wangpaichitr, Chunjing Wu, Ying Ying Li, Lynn G. Feun, Macus T. Kuo, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4404.
https://doi.org/10.1158/1538-7445.AM2017-4404
Published: 01 July 2017
View article titled, Abstract 4404: Novel approach to circumvent cisplatin resistant lung cancer by targeting metabolism
Journal Articles

Abstract 3712: The relationship of Procollagen alpha 1 type 1 (Col1A1) / DDR2 signaling in malignant glioma and sensitivity to STAT 3/5 inhibitor

Free
Shumei Chen, Chunjing Wu, Ying-Ying Li, Medhi Wangpaichitr, Ronald J. Benveniste, James Turkson, Niramol Savaraj, Lynn G. Feun
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3712.
https://doi.org/10.1158/1538-7445.AM2016-3712
Published: 15 July 2016
View article titled, Abstract 3712: The relationship of Procollagen alpha 1 type 1 (Col1A1) / DDR2 signaling in malignant glioma and sensitivity to STAT 3/5 inhibitor
Journal Articles

Abstract 1038: Exploiting ROS and metabolic differences to selectively killing cisplatin resistant lung cancer

Free
Medhi Wangpaichitr, Chunjing Wu, Ying Ying Li, Sumedh Shah, Shu-Mei Chen, Vy Dinh, Macus T. Kuo, Lynn G. Feun, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1038.
https://doi.org/10.1158/1538-7445.AM2016-1038
Published: 15 July 2016
View article titled, Abstract 1038: Exploiting ROS and metabolic differences to selectively killing cisplatin resistant lung cancer
Journal Articles

Abstract 2671: BRAF inhibitor resistance reprograms metabolic and survival pathways to sensitize melanoma cells to arginine deprivation

Free
Ying-Ying Li, Chunjing Wu, Sumedh Shah, Shu-Mei Chen, Medhi Wangpaichitr, Lynn Feun, Macus Kuo, Miguel Suarez, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2671.
https://doi.org/10.1158/1538-7445.AM2016-2671
Published: 15 July 2016
View article titled, Abstract 2671: BRAF inhibitor resistance reprograms metabolic and survival pathways to sensitize melanoma cells to arginine deprivation
Journal Articles

Abstract 2900: Biochemical alterations in BRAF inhibitor (BRAFi) resistant melanoma cells increase their vulnerability to arginine deprivation

Free
Ying-Ying Li, Niramol Savaraj, Chunjing Wu, Shumei Chen, Medhi Wangpaichitr, Macus T. Kuo, Lynn G. Feun
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2900.
https://doi.org/10.1158/1538-7445.AM2015-2900
Published: 01 August 2015
View article titled, Abstract 2900: Biochemical alterations in BRAF inhibitor (BRAFi) resistant melanoma cells increase their vulnerability to arginine deprivation
Journal Articles

Abstract 43: The role of discoidin domain receptor 2 (DDR2) and its relationship with procollagen alpha 1 type 1(Col1A1) in malignant glioma

Free
Shumei Chen, Chunjing Wu, Ying Ying Li, Medhi Wangpaichitr, Lynn G. Feun, Ronald Benveniste, Vy Dinh, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 43.
https://doi.org/10.1158/1538-7445.AM2015-43
Published: 01 August 2015
View article titled, Abstract 43: The role of discoidin domain receptor 2 (DDR2) and its relationship with procollagen alpha 1 type 1(Col1A1) in malignant glioma
Journal Articles

Abstract 1206: Cisplatin resistant non small cell lung cancer is sensitive to arginine deprivation therapy

Free
Medhi Wangpaichitr, Chunjing Wu, Dao M. Nguyen, Min You, Ying Ying Li, Shumei Chen, Lynn G. Feun, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1206.
https://doi.org/10.1158/1538-7445.AM2015-1206
Published: 01 August 2015
View article titled, Abstract 1206: Cisplatin resistant non small cell lung cancer is sensitive to arginine deprivation therapy
Journal Articles

Abstract 1428: Targeting metabolic alteration in cisplatin-resistant lung cancer

Free
Medhi Wangpaichitr, Chunjing Wu, Ying Ying Li, Shumei Chen, Min You, Vy Dinh, Lynn G. Feun, Macus T. Kuo, Niramol Savaraj
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1428.
https://doi.org/10.1158/1538-7445.AM2014-1428
Published: 01 October 2014
View article titled, Abstract 1428: Targeting metabolic alteration in cisplatin-resistant lung cancer
Journal Articles

Abstract 1435: Exploiting obligate arginine auxotrophy in tumor cells lacking arginino-succinate synthetase (ASS) expression to develop targeted molecular therapy for non-small cell lung cancer (NSCLC)

Free
Min You, Medhi Wangpaichitr, Jonathan D. Nguyen, Jennifer R. Chapman, Maureen Cioffi-Lavina, Niramol Savaraj, Dao M. Nguyen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1435.
https://doi.org/10.1158/1538-7445.AM2014-1435
Published: 01 October 2014
View article titled, Abstract 1435: Exploiting obligate arginine auxotrophy in tumor cells lacking arginino-succinate synthetase (ASS) expression to develop targeted molecular therapy for non-small cell lung cancer (NSCLC)