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Ninel Azoitei
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Journal Articles

RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic Cancer

Frank Arnold, Johann Gout, Heike Wiese, Stephanie E. Weissinger, Elodie Roger, Lukas Perkhofer, Karolin Walter, Jeanette Scheible, Caterina Prelli Bozzo, André Lechel, Thomas J. Ettrich, Ninel Azoitei, Li Hao, Axel Fürstberger, Ewa K. Kaminska, Konstantin M.J. Sparrer, Volker Rasche, Sebastian Wiese, Hans A. Kestler, Peter Möller, Thomas Seufferlein, Pierre-Olivier Frappart, Alexander Kleger
Journal: Cancer Research
Cancer Res (2021) 81 (7): 1758–1774.
https://doi.org/10.1158/0008-5472.CAN-20-2633
Published: 01 April 2021
View article titled, RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic Cancer
Open the PDF for RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 3437: Requirement for YAP1 signaling in myxoid liposarcoma

Marcel Trautmann, Ya-Yun Cheng, Patrizia Jensen, Ninel Azoitei, Ines Brunner, Jennifer Hüllein, Mikolaj Slabicki, Ilka Isfort, Magdalene Cyra, Eva Wardelmann, Sebastian Huss, Bianca Altvater, Claudia Rossig, Susanne Hafner, Thomas Simmet, Anders Ståhlberg, Pierre Åman, Thorsten Zenz, Undine Lange, Thomas Kindler, Claudia Scholl, Wolfgang Hartmann, Stefan Fröhling
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3437.
https://doi.org/10.1158/1538-7445.AM2019-3437
Published: 01 July 2019
View article titled, Abstract 3437: Requirement for YAP1 signaling in myxoid liposarcoma
Journal Articles

ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage

Lukas Perkhofer, Anna Schmitt, Maria Carolina Romero Carrasco, Michaela Ihle, Stephanie Hampp, Dietrich Alexander Ruess, Elisabeth Hessmann, Ronan Russell, André Lechel, Ninel Azoitei, Qiong Lin, Stefan Liebau, Meike Hohwieler, Hanibal Bohnenberger, Marina Lesina, Hana Algül, Laura Gieldon, Evelin Schröck, Jochen Gaedcke, Martin Wagner, Lisa Wiesmüller, Bence Sipos, Thomas Seufferlein, Hans Christian Reinhardt, Pierre-Olivier Frappart, Alexander Kleger
Journal: Cancer Research
Cancer Res (2017) 77 (20): 5576–5590.
https://doi.org/10.1158/0008-5472.CAN-17-0634
Published: 15 October 2017
View article titled, ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage
Open the PDF for ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage in another window
Includes: Supplementary data
Journal Articles

Abstract 1809: PKM2 promotes tumor angiogenesis by regulating HIF-1alpha through NF-kappaB activation

Ninel Azoitei, Alexander Becher, Konrad Steinestel, Arefeh Rouhi, Kristina Diepold, Susanne Bobrovich, Thomas Seufferlein
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1809.
https://doi.org/10.1158/1538-7445.AM2017-1809
Published: 01 July 2017
View article titled, Abstract 1809: PKM2 promotes tumor angiogenesis by regulating HIF-1alpha through NF-kappaB activation
Journal Articles

Abstract 1435: Role of PRKD2 in HSP90- and hypoxia-mediated epithelial-to-mesenchymal transition

Ninel Azoitei, Alexander Becher, Kristina Diepold, Susanne Bobrovich, Cornelia Brunner, Gabriela Chiosis, Stefan Fröhling, van Lint Johan, Claudia Scholl, Thomas Seufferlein
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1435.
https://doi.org/10.1158/1538-7445.AM2015-1435
Published: 01 August 2015
View article titled, Abstract 1435: Role of PRKD2 in HSP90- and hypoxia-mediated epithelial-to-mesenchymal transition
Journal Articles

HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization

Ninel Azoitei, Kristina Diepold, Cornelia Brunner, Arefeh Rouhi, Felicitas Genze, Alexander Becher, Hans Kestler, Johan van Lint, Gabriela Chiosis, John Koren, III, Stefan Fröhling, Claudia Scholl, Thomas Seufferlein
Journal: Cancer Research
Cancer Res (2014) 74 (23): 7125–7136.
https://doi.org/10.1158/0008-5472.CAN-14-1017
Published: 30 November 2014
View article titled, HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization
Open the PDF for HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization in another window
Includes: Supplementary data
Journal Articles

Abstract 5129: Role of PRKD2 in HSP90 inhibition-mediated suppression of cancer growth

Ninel Azoitei, Kristina Diepold, Felicitas Genze, Arefeh Rouhi, Susanne Brobovich, Stefan Froehling, Gabriela Chiosis, Cornelia Brunner, Johan van Lint, Marcus Cronauer, Claudia Scholl, Thomas Seufferlein
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5129.
https://doi.org/10.1158/1538-7445.AM2014-5129
Published: 01 October 2014
View article titled, Abstract 5129: Role of PRKD2 in HSP90 inhibition-mediated suppression of cancer growth
Journal Articles

Abstract 2773: HSP90 inhibitors target KRAS mutant human tumors through degradation of STK33

Ninel Azoitei, Christopher M. Hoffmann, Jana M. Ellegast, Claudia R. Ball, Kerstin Obermayer, Ulrike Gößele, Britta Koch, Katrin Faber, Felicitas Genze, Mark Schrader, Hans A. Kestler, Hartmut Döhner, Gabriela Chiosis, Hanno Glimm, Stefan Fröhling, Claudia Scholl
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2773.
https://doi.org/10.1158/1538-7445.AM2012-2773
Published: 15 April 2012
View article titled, Abstract 2773: HSP90 inhibitors target KRAS mutant human tumors through degradation of STK33