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Nicolas André
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Journal Articles

Abstract 1204: Very high throughput genome sequencing for pediatric cancers in France

Ludovic Lacroix, Gaelle Pierron, Julien Masliah Planchon, Marc Barritault, Adrien Buisson, Alain Viari, Tiphaine Adam-De-Beaumais, Gaelle Tachon, Valery Attignon, Helene Cavé, Helene Lapillonne, Pascale Flandrin-Gresta, Eric Delabesse, Sylvie Tondeur, Mathilde Laubert, Isabelle Rochet, Imene Hezam, Silvana Beatriz Dangiolo, Samuel Abbou, Pablo Berlanga, Jacques Grill, Franck Bourdeaut, Natacha Entz-Werle, Pierre Leblond, Nicolas André, Gabriel Revon-Riviere, Antony Ceraulo, Marion Strullu, Pierre Rohrlich, Arnaud Petit, Stephane Ducassou, Lea Guerrini-Rousseau, Claudia Pasqualini, Gudrun Schleiermacher, Nadege Corradini, Birgit Geoerger
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1204.
https://doi.org/10.1158/1538-7445.AM2025-1204
Published: 21 April 2025
View articletitled, Abstract 1204: Very high throughput genome sequencing for pediatric cancers in France
Journal Articles

ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma

Evangeline R. Jackson, Ryan J. Duchatel, Dilana E. Staudt, Mika L. Persson, Abdul Mannan, Sridevi Yadavilli, Sarah Parackal, Shaye Game, Wai Chin Chong, W. Samantha N. Jayasekara, Marion Le Grand, Padraic S. Kearney, Alicia M. Douglas, Izac J. Findlay, Zacary P. Germon, Holly P. McEwen, Tyrone S. Beitaki, Adjanie Patabendige, David A. Skerrett-Byrne, Brett Nixon, Nathan D. Smith, Bryan Day, Neevika Manoharan, Sumanth Nagabushan, Jordan R. Hansford, Dinisha Govender, Geoff B. McCowage, Ron Firestein, Meegan Howlett, Raelene Endersby, Nicholas G. Gottardo, Frank Alvaro, Sebastian M. Waszak, Martin R. Larsen, Yolanda Colino-Sanguino, Fatima Valdes-Mora, Andria Rakotomalala, Samuel Meignan, Eddy Pasquier, Nicolas André, Esther Hulleman, David D. Eisenstat, Nicholas A. Vitanza, Javad Nazarian, Carl Koschmann, Sabine Mueller, Jason E. Cain, Matthew D. Dun
Journal: Cancer Research
Cancer Res (2023) 83 (14): 2421–2437.
https://doi.org/10.1158/0008-5472.CAN-23-0186
Published: 14 July 2023
View articletitled, ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma
Open the PDF for ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma in another window
Includes: Supplementary data
Journal Articles

Abstract CT019: Phase I/II study of the PARP inhibitor olaparib and ATR inhibitor ceralasertib in children with advanced malignancies: Arm N of the AcSé-ESMART trial

Susanne A. Gatz, Alba Rubio San Simón, Baptiste Archambaud, Samuel Abbou, Morgane Cleirec, Amaury Leruste, Anne-Sophie Defachelles, Nicolas André, Jonathan Rubino, Souad Nebchi, Windy Rondof, Simon A. Smith, Peter G. Mortimer, Bienvenu Loembé, Gwenael Le Teuff, Gilles Vassal, Birgit Geoerger
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT019.
https://doi.org/10.1158/1538-7445.AM2023-CT019
Published: 29 May 2023
View articletitled, Abstract CT019: Phase I/II study of the PARP inhibitor olaparib and ATR inhibitor ceralasertib in children with advanced malignancies: Arm N of the AcSé-ESMART trial
Journal Articles

Abstract CT088: Phase I/II study of the PARP inhibitor olaparib in combination with irinotecan in children with advanced malignancies: arm D of the AcSé-ESMART trial

Susanne A. Gatz, Pablo Berlanga, Baptiste Archambaud, Yassine Bouchoucha, Nicolas André, Nadege Corradini, Windy Rondof, Jonathan Rubino, Souad Nebchi, Antonin Marchais, Estelle Thebaud, Alba Rubio San Simón, Natasha K. van Eijkelenburg, Lynley V. Marshall, Anne-Sophie Defachelles, Adela Canyete, Stephane Ducassou, Guy Makin, Michela Casanova, Emilie De Carli, Arnaud Petit, Gwenael Le Teuff, Xavier Paoletti, Peter G. Mortimer, Gilles Vassal, Birgit Geoerger
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT088.
https://doi.org/10.1158/1538-7445.AM2023-CT088
Published: 14 April 2023
View articletitled, Abstract CT088: Phase I/II study of the PARP inhibitor olaparib in combination with irinotecan in children with advanced malignancies: arm D of the AcSé-ESMART trial
Journal Articles

Abstract CT087: Phase I/II study of the WEE1 inhibitor adavosertib in combination with carboplatin in children with advanced malignancies: arm C of the AcSé-ESMART trial

Susanne A. Gatz, Anne C. Harttrampf, Caroline Brard, Francisco J. Bautista, Nicolas André, Samuel Abbou, Jonathan Rubino, Windy Rondof, Marc Deloger, Marc Rübsam, Daniel Hübschmann, Lynley V. Marshall, Souad Nebchi, Isabelle Aerts, Estelle Thebaud, Emilie De Carli, Anne-Sophie Defachelles, Xavier Paoletti, Robert Godin, Kowser Miah, Peter G. Mortimer, Gilles Vassal, Birgit Geoerger
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT087.
https://doi.org/10.1158/1538-7445.AM2023-CT087
Published: 14 April 2023
View articletitled, Abstract CT087: Phase I/II study of the WEE1 inhibitor adavosertib in combination with carboplatin in children with advanced malignancies: arm C of the AcSé-ESMART trial
Journal Articles

Abstract 2022: Model-informed pediatric drug development: oral vinorelbine in low-grade glioma as a case study

Mourad HAMIMED, Pierre LEBLOND, Aurélie DUMONT, Florence GATTACCECA, Emmanuelle TRESCH-BRUNEEL, Alicia PROBST, Pascal CHASTAGNER, Anne PAGNIER, Emilie DE CARLI, Natacha ENTZ-WERLÉ, Jacques GRILL, Isabelle AERTS, Didier FRAPPAZ, Anne-Isabelle BERTOZZI-SALAMON, Caroline SOLAS, Nicolas ANDRÉ, Joseph Ciccolini
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2022.
https://doi.org/10.1158/1538-7445.AM2022-2022
Published: 15 June 2022
View articletitled, Abstract 2022: Model-informed pediatric drug development: oral vinorelbine in low-grade glioma as a case study
Journal Articles

Abstract CT136: Phase I study with rapamycin combined with irinotecan, the SFCE RAPIRI I trial, a new way to target tumor hypoxia in pediatric refractory cancers

Sarah Jannier, Veronique Kemmel, Consuelo Sebastia, Agathe Chammas, Amelia-Naomi Sabo, Erwan Pencreach, Françoise Farace, Benoit Lhermitte, Birgit Geoerger, Isabelle Aerts, Didier Frappaz, Pierre Leblond, Nicolas Andre, Yves Perel, Nadège Corradini, Anne Isabelle Bertozzi, Florence Vincent, Natacha Entz-Werle
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT136.
https://doi.org/10.1158/1538-7445.AM2020-CT136
Published: 15 August 2020
View articletitled, Abstract CT136: Phase I study with rapamycin combined with irinotecan, the SFCE RAPIRI I trial, a new way to target tumor hypoxia in pediatric refractory cancers
Journal Articles

Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy

Joseph Ciccolini, Dominique Barbolosi, Christophe Meille, Aurélie Lombard, Cindy Serdjebi, Sarah Giacometti, Laetitia Padovani, Eddy Pasquier, Nicolas André
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4723–4733.
https://doi.org/10.1158/0008-5472.CAN-16-3130
Published: 31 August 2017
View articletitled, Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy
Open the PDF for Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy

Raphael Serre, Sebastien Benzekry, Laetitia Padovani, Christophe Meille, Nicolas André, Joseph Ciccolini, Fabrice Barlesi, Xavier Muracciole, Dominique Barbolosi
Journal: Cancer Research
Cancer Res (2016) 76 (17): 4931–4940.
https://doi.org/10.1158/0008-5472.CAN-15-3567
Published: 31 August 2016
View articletitled, Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy
Open the PDF for Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract 2572: Metronomic scheduling: a promising strategy to manage intratumor heterogeneity and control treatment resistance

Manon Carre, Maryna Bondarenko, Marie-Pierre Montero, Guillemette Chapuisat, Assia Benabdallah, Marion Le Grand, Diane Braguer, Nicolas Andre, Eddy Pasquier
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2572.
https://doi.org/10.1158/1538-7445.AM2015-2572
Published: 01 August 2015
View articletitled, Abstract 2572: Metronomic scheduling: a promising strategy to manage intratumor heterogeneity and control treatment resistance
Journal Articles

Abstract 4506: Computational-driven metronomics: application to gemcitabine in neuroblastoma-bearing mice

Joseph Ciccolini, Eddy Pasquier, Aurelie Lombard, Sarah Giacometti, Christian Faivre, Raphaelle Fanciullino, Cindy Serdjebi, Dominique Barbolosi, Nicolas Andre
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4506.
https://doi.org/10.1158/1538-7445.AM2015-4506
Published: 01 August 2015
View articletitled, Abstract 4506: Computational-driven metronomics: application to gemcitabine in neuroblastoma-bearing mice
Journal Articles

Abstract 5549: Recipient-donor contradictory genotype with impact on anticancer drug pharmacogenetics after liver transplant: A deadly gift

Cindy Serdjebi, Raphaelle Fanciullino, Frederic Fina, Arnaud Verschuur, Bertrand Roquelaure, Bruno Lacarelle, L'Houcine Ouafik, Joseph Ciccolini, Nicolas André
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5549.
https://doi.org/10.1158/1538-7445.AM2014-5549
Published: 01 October 2014
View articletitled, Abstract 5549: Recipient-donor contradictory genotype with impact on anticancer drug pharmacogenetics after liver transplant: A deadly gift
Journal Articles

Abstract 4625: Age dependence of doxorubicin pharmacokinetics in pediatric cancer patients; results of an FP7-funded clinical study

Alan V. Boddy, Nicolas Andre, Gianni Bisogno, Joachim Boos, Maurizio D'Incalci, Nina Kontny, Miriam Krischke, Swantje Voeller, Georg Hempel
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4625.
https://doi.org/10.1158/1538-7445.AM2014-4625
Published: 01 October 2014
View articletitled, Abstract 4625: Age dependence of doxorubicin pharmacokinetics in pediatric cancer patients; results of an FP7-funded clinical study
Journal Articles

Abstract 2219: The European Paediatric Oncology off-patent medicines Consortium (EPOC) pharmacokinetic/pharmacodynamic study of doxorubicin.

Alan V. Boddy, Alison J. Steel, Joachim Boos, Miriam Krischke, Nicolas Andre, Gianni Bisogno, Georg Hempel, Gerlind Bode, Maurizio D'Incalci, Nina Kontny
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2219.
https://doi.org/10.1158/1538-7445.AM2013-2219
Published: 15 April 2013
View articletitled, Abstract 2219: The European Paediatric Oncology off-patent medicines Consortium (EPOC) pharmacokinetic/pharmacodynamic study of doxorubicin.
Journal Articles

Phenotypic determination of CDA status: Animal study and application in paediatric oncology

Nicolas Andre, Adrien Ortiz, Cedric Mercier, Sarah Giacometti, Jean-Marc Feuerstein, Caroline Brunet, Laurence Camoin-Jau, Jean-Louis Bernard, Joseph Ciccolini
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4806A.
Published: 01 May 2008
View articletitled, Phenotypic determination of CDA status: Animal study and application in paediatric oncology
Journal Articles

Toxic-death case upon gemcitabine/carboplatin administration: probable implication of cytidine deaminase gene polymorphism

Joseph Ciccolini, Laetitia Dahan, Alexandre Evrard, Caroline Raynal, Adrien Ortiz, Sarah Giacometti, Fleur Franceschini, Aurore Blesius, Aude Le Goffic, Nicolas Andre, Gerard Milano, Roger Favre, Jean-Francois Seitz, Cedric Mercier
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 740.
Published: 01 May 2007
View articletitled, Toxic-death case upon gemcitabine/carboplatin administration: probable implication of cytidine deaminase gene polymorphism