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Nicholas B. La Thangue
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Journal Articles

TLR Adaptor Protein MYD88 Mediates Sensitivity to HDAC Inhibitors via a Cytokine-Dependent Mechanism

Free
Maria New, Semira Sheikh, Mina Bekheet, Heidi Olzscha, Marie-Laetitia Thezenas, Matthew A. Care, Susan Fotheringham, Reuben M. Tooze, Benedikt Kessler, Nicholas B. La Thangue
Journal: Cancer Research
Cancer Res (2016) 76 (23): 6975–6987.
https://doi.org/10.1158/0008-5472.CAN-16-0504
Published: 30 November 2016
View articletitled, TLR Adaptor Protein MYD88 Mediates Sensitivity to HDAC Inhibitors via a Cytokine-Dependent Mechanism
Open the PDF for TLR Adaptor Protein MYD88 Mediates Sensitivity to HDAC Inhibitors via a Cytokine-Dependent Mechanism in another window
Includes: Supplementary data
Journal Articles

Abstract B40: WEE1 inhibition selectively kills histone H3K36me3-deficient cancers by dNTP starvation

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Sophia X. Pfister, Enni Markkanen, Yanyan Jiang, Sovan Sarkar, Mick Woodcock, Lykourgos-Panagiotis Zalmas, Giulia Orlando, Neele Drobnitzky, Grigory Dianov, Songmin Ying, Nicholas B. La Thangue, Vincenzo D'Angiolella, Anderson Ryan, Timothy C. Humphrey
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): B40.
https://doi.org/10.1158/1538-7445.CHROMEPI15-B40
Published: 14 January 2016
View articletitled, Abstract B40: WEE1 inhibition selectively kills histone H3K36me3-deficient cancers by dNTP starvation
Journal Articles

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

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Sarah Picaud, Oleg Fedorov, Angeliki Thanasopoulou, Katharina Leonards, Katherine Jones, Julia Meier, Heidi Olzscha, Octovia Monteiro, Sarah Martin, Martin Philpott, Anthony Tumber, Panagis Filippakopoulos, Clarence Yapp, Christopher Wells, Ka Hing Che, Andrew Bannister, Samuel Robson, Umesh Kumar, Nigel Parr, Kevin Lee, Dave Lugo, Philip Jeffrey, Simon Taylor, Matteo L. Vecellio, Chas Bountra, Paul E. Brennan, Alison O'Mahony, Sharlene Velichko, Susanne Müller, Duncan Hay, Danette L. Daniels, Marjeta Urh, Nicholas B. La Thangue, Tony Kouzarides, Rab Prinjha, Jürg Schwaller, Stefan Knapp
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (23): 5106–5119.
https://doi.org/10.1158/0008-5472.CAN-15-0236
Published: 30 November 2015
View articletitled, Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
Open the PDF for Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy in another window
Includes: Supplementary data
Journal Articles

Regulation of E2F4 Mitogenic Activity during Terminal Differentiation by Its Heterodimerization Partners for Nuclear Translocation

Free
Pier Lorenzo Puri, Letizia Cimino, Marcella Fulco, Christian Zimmerman, Nicholas B. La Thangue, Antonio Giordano, Adolf Graessmann, Massimo Levrero
Journal: Cancer Research
Cancer Res (1998) 58 (7): 1325–1331.
Published: 01 April 1998
View articletitled, Regulation of E2F4 Mitogenic Activity during Terminal Differentiation by Its Heterodimerization Partners for Nuclear Translocation
Open the PDF for Regulation of E2F4 Mitogenic Activity during Terminal Differentiation by Its Heterodimerization Partners for Nuclear Translocation in another window