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Nelson Rhodes
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Journal Articles

Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Nelson Rhodes, Dirk A. Heerding, Derek R. Duckett, Derek J. Eberwein, Victoria B. Knick, Timothy J. Lansing, Randy T. McConnell, Tona M. Gilmer, Shu-Yun Zhang, Kimberly Robell, Jason A. Kahana, Robert S. Geske, Elena V. Kleymenova, Anthony E. Choudhry, Zhihong Lai, Jack D. Leber, Elisabeth A. Minthorn, Susan L. Strum, Edgar R. Wood, Pearl S. Huang, Robert A. Copeland, Rakesh Kumar
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2366–2374.
https://doi.org/10.1158/0008-5472.CAN-07-5783
Published: 01 April 2008
View article titled, Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
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Includes: Supplementary data
Journal Articles

GSK690693, a pan-AKT kinase inhibitor with potent pharmacodynamic and antitumor activity in vivo.

Rakesh Kumar, Nelson Rhodes, Victoria Knick, Derek Eberwein, Derek Duckett, ShuYun Zhang, Tona Gilmer, Jack Leber, Elena Kleymenova, Rob Geske, Elisabeth Minthorn, Dirk Heerding, Pearl Huang
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 277.
Published: 01 May 2007
View article titled, GSK690693, a pan-AKT kinase inhibitor with potent pharmacodynamic and antitumor activity in vivo.
Journal Articles

GSK690693, a pan-AKT kinase inhibitor has potent anti-tumor activity and shows additive effect with lapatinib.

Nelson Rhodes, Victoria Knick, Randy McConnell, Timothy Lansing, David Rusnak, Derek Duckett, Tona Gilmer, Jason Kahana, Kimerly Robell, Jack Leber, Anthony Choudhry, Zhihong Lai, Edgar Wood, Susan Strum, Dirk Heerding, Pearl Huang, Rakesh Kumar
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 279.
Published: 01 May 2007
View article titled, GSK690693, a pan-AKT kinase inhibitor has potent anti-tumor activity and shows additive effect with lapatinib.
Journal Articles

Identification of a novel inhibitor of AKT kinase, GSK690693.

Dirk Heerding, Nelson Rhodes, Jack Leber, Anthony Choudhry, Tammy Clark, Nestor Concha, Derek Duckett, Derek Eberwein, Robert Geske, Tona Gilmer, Pearl Huang, Jason Kahana, Richard Keenan, Elena Kleymenova, Victoria Knick, Louis Lafrance, Zhihong Lai, Timothy Lansing, Mei Li, Elisabeth Minthorn, Kimberly Robell, David Rusnak, Igor Safonov, Edgar Wood, Rakesh Kumar
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): ND-2.
Published: 01 May 2007
View article titled, Identification of a novel inhibitor of AKT kinase, GSK690693.
Journal Articles

Synergistic induction of apoptosis between GW572016 and inhibitors of phosphatidylinositol 3-kinase/AKT pathway

Robert L. Tansik, Sara C. Singer, Steven L. Knapp, Nelson Rhodes, Tona M. Gilmer, Inderjit K. Dev
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1076.
Published: 01 April 2004
View article titled, Synergistic induction of apoptosis between GW572016 and inhibitors of phosphatidylinositol 3-kinase/AKT pathway
Journal Articles

Defective G2 Checkpoint Function in Cells from Individuals with Familial Cancer Syndromes

Richard S. Paules, Eleni N. Levedakou, Sandra J. Wilson, Cynthia L. Innes, Nelson Rhodes, Thea D. Tlsty, Denise A. Galloway, Lawrence A. Donehower, Michael A. Tainsky, William K. Kaufmann
Journal: Cancer Research
Cancer Res (1995) 55 (8): 1763–1773.
Published: 01 April 1995
View article titled, Defective G<sub>2</sub> Checkpoint Function in Cells from Individuals with Familial Cancer Syndromes
Open the PDF for Defective G<sub>2</sub> Checkpoint Function in Cells from Individuals with Familial Cancer Syndromes in another window