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Nejat K. Egilmez
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Journal Articles

Dietary Fats High in Linoleic Acids Impair Antitumor T-cell Responses by Inducing E-FABP–Mediated Mitochondrial Dysfunction

Rong Jin, Jiaqing Hao, Yanmei Yi, Di Yin, Yuan Hua, Xiaohong Li, Hanmei Bao, Xianlin Han, Nejat K. Egilmez, Edward R. Sauter, Bing Li
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5296–5310.
https://doi.org/10.1158/0008-5472.CAN-21-0757
Published: 15 October 2021
View articletitled, Dietary Fats High in Linoleic Acids Impair Antitumor T-cell Responses by Inducing E-FABP–Mediated Mitochondrial Dysfunction
Open the PDF for Dietary Fats High in Linoleic Acids Impair Antitumor T-cell Responses by Inducing E-FABP–Mediated Mitochondrial Dysfunction in another window
Includes: Supplementary data
Journal Articles

Consumption of the Fish Oil High-Fat Diet Uncouples Obesity and Mammary Tumor Growth through Induction of Reactive Oxygen Species in Protumor Macrophages

Lianliang Liu, Rong Jin, Jiaqing Hao, Jun Zeng, Di Yin, Yanmei Yi, Mingming Zhu, Anita Mandal, Yuan Hua, Chin K. Ng, Nejat K. Egilmez, Edward R. Sauter, Bing Li
Journal: Cancer Research
Cancer Res (2020) 80 (12): 2564–2574.
https://doi.org/10.1158/0008-5472.CAN-19-3184
Published: 15 June 2020
View articletitled, Consumption of the Fish Oil High-Fat Diet Uncouples Obesity and Mammary Tumor Growth through Induction of Reactive Oxygen Species in Protumor Macrophages
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Includes: Supplementary data
Journal Articles

Abstract 4145: A novel form of 4-1BB agonist shows robust immune protection against various tumor types through CD4+ memory-like T and NK cell axis

Haval Shirwan, Hampartsoum B. Barsoumian, Lalit Batra, Pradeep Shrestha, William S. Bowen, Hong Zhao, Nejat K. Egilmez, Jorge G. Gomez-Gutierrez, Esma S. Yolcu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4145.
https://doi.org/10.1158/1538-7445.AM2019-4145
Published: 01 July 2019
View articletitled, Abstract 4145: A novel form of 4-1BB agonist shows robust immune protection against various tumor types through CD4+ memory-like T and NK cell axis
Journal Articles

A Novel Form of 4-1BBL Prevents Cancer Development via Nonspecific Activation of CD4+ T and Natural Killer Cells

Hampartsoum B. Barsoumian, Lalit Batra, Pradeep Shrestha, William S. Bowen, Hong Zhao, Nejat K. Egilmez, Jorge G. Gomez-Gutierrez, Esma S. Yolcu, Haval Shirwan
Journal: Cancer Research
Cancer Res (2019) 79 (4): 783–794.
https://doi.org/10.1158/0008-5472.CAN-18-2401
Published: 15 February 2019
View articletitled, A Novel Form of 4-1BBL Prevents Cancer Development via Nonspecific Activation of CD4+ T and Natural Killer Cells
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Journal Articles

Abstract LB-172: Novel mechanistic insight into the prevention and treatment of colorectal cancer and familial adenomatous polyposis by anthocyanidins

Ashley M. Mudd, Tao Gu, Jeyaprakash Jeyabalan, Radha Munagala, Nejat K. Egilmez, Ramesh C. Gupta
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-172.
https://doi.org/10.1158/1538-7445.AM2018-LB-172
Published: 01 July 2018
View articletitled, Abstract LB-172: Novel mechanistic insight into the prevention and treatment of colorectal cancer and familial adenomatous polyposis by anthocyanidins
Journal Articles

Expression of Adipocyte/Macrophage Fatty Acid–Binding Protein in Tumor-Associated Macrophages Promotes Breast Cancer Progression

Jiaqing Hao, Fei Yan, Yuwen Zhang, Ashley Triplett, Ying Zhang, Debra A. Schultz, Yanwen Sun, Jun Zeng, Kevin A.T. Silverstein, Qi Zheng, David A. Bernlohr, Margot P. Cleary, Nejat K. Egilmez, Edward Sauter, Shujun Liu, Jill Suttles, Bing Li
Journal: Cancer Research
Cancer Res (2018) 78 (9): 2343–2355.
https://doi.org/10.1158/0008-5472.CAN-17-2465
Published: 30 April 2018
View articletitled, Expression of Adipocyte/Macrophage Fatty Acid–Binding Protein in Tumor-Associated Macrophages Promotes Breast Cancer Progression
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Includes: Supplementary data
Journal Articles

Abstract 1605: Combined oral cytokine therapy effectively treats colon cancer in a murine model

Neal Bhutiani, Qingsheng Li, Charles D. Anderson, Tao Gu, Nejat K. Egilmez
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1605.
https://doi.org/10.1158/1538-7445.AM2017-1605
Published: 01 July 2017
View articletitled, Abstract 1605: Combined oral cytokine therapy effectively treats colon cancer in a murine model
Journal Articles

Abstract 1620: Oral IL-10 suppresses colon carcinogenesis via elimination of pathogenic CD4+ T-cells and induction of antitumor CD8+ T-cell activity

TAO GU, Magdia DeJesus, Thomas P. Burris, Nejat K. Egilmez
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1620.
https://doi.org/10.1158/1538-7445.AM2017-1620
Published: 01 July 2017
View articletitled, Abstract 1620: Oral IL-10 suppresses colon carcinogenesis via elimination of pathogenic CD4+ T-cells and induction of antitumor CD8+ T-cell activity
Journal Articles

Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites

Qilong Wang, Yi Ren, Jingyao Mu, Nejat K. Egilmez, Xiaoyin Zhuang, Zhongbin Deng, Lifeng Zhang, Jun Yan, Donald Miller, Huang-Ge Zhang
Journal: Cancer Research
Cancer Res (2015) 75 (12): 2520–2529.
https://doi.org/10.1158/0008-5472.CAN-14-3095
Published: 14 June 2015
View articletitled, Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites
Open the PDF for Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites in another window
Includes: Supplementary data
Journal Articles

Oral Interleukin-10 Alleviates Polyposis via Neutralization of Pathogenic T-Regulatory Cells

Allen Y. Chung, Qingsheng Li, Sarah J. Blair, Magdia De Jesus, Kristen L. Dennis, Charles LeVea, Jin Yao, Yijun Sun, Thomas F. Conway, Lauren P. Virtuoso, Nicholas G. Battaglia, Stacia Furtado, Edith Mathiowitz, Nicholas J. Mantis, Khashayarsha Khazaie, Nejat K. Egilmez
Journal: Cancer Research
Cancer Res (2014) 74 (19): 5377–5385.
https://doi.org/10.1158/0008-5472.CAN-14-0918
Published: 30 September 2014
View articletitled, Oral Interleukin-10 Alleviates Polyposis via Neutralization of Pathogenic T-Regulatory Cells
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Journal Articles

Central Role of IFNγ–Indoleamine 2,3-Dioxygenase Axis in Regulation of Interleukin-12–Mediated Antitumor Immunity

Tao Gu, Rachael B. Rowswell-Turner, Mehmet O. Kilinc, Nejat K. Egilmez
Journal: Cancer Research
Cancer Res (2010) 70 (1): 129–138.
https://doi.org/10.1158/0008-5472.CAN-09-3170
Published: 04 January 2010
View articletitled, Central Role of IFNγ–Indoleamine 2,3-Dioxygenase Axis in Regulation of Interleukin-12–Mediated Antitumor Immunity
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Includes: Supplementary data
Journal Articles

Cancer Immunotherapy with Interleukin 12 and Granulocyte-Macrophage Colony-stimulating Factor-encapsulated Microspheres: Coinduction of Innate and Adaptive Antitumor Immunity and Cure of Disseminated Disease

Hank C. Hill, Thomas F. Conway, Jr., Michael S. Sabel, Yong S. Jong, Edith Mathiowitz, Richard B. Bankert, Nejat K. Egilmez
Journal: Cancer Research
Cancer Res (2002) 62 (24): 7254–7263.
Published: 15 December 2002
View articletitled, Cancer Immunotherapy with Interleukin 12 and Granulocyte-Macrophage Colony-stimulating Factor-encapsulated Microspheres: Coinduction of Innate and Adaptive Antitumor Immunity and Cure of Disseminated Disease
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Journal Articles

Human CD4+ Effector T Cells Mediate Indirect Interleukin-12- and Interferon-γ-dependent Suppression of Autologous HLA-negative Lung Tumor Xenografts in Severe Combined Immunodeficient Mice

Nejat K. Egilmez, Stephen D. Hess, Fang-An Chen, Hiroshi Takita, Thomas F. Conway, Richard B. Bankert
Journal: Cancer Research
Cancer Res (2002) 62 (9): 2611–2617.
Published: 01 May 2002
View articletitled, Human CD4+ Effector T Cells Mediate Indirect Interleukin-12- and Interferon-γ-dependent Suppression of Autologous HLA-negative Lung Tumor Xenografts in Severe Combined Immunodeficient Mice
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Journal Articles

Antibody Targeting of Doxorubicin-loaded Liposomes Suppresses the Growth and Metastatic Spread of Established Human Lung Tumor Xenografts in Severe Combined Immunodeficient Mice

Masahiko Sugano, Nejat K. Egilmez, Sandra J. Yokota, Fang-An Chen, Jennifer Harding, Shi Kun Huang, Richard B. Bankert
Journal: Cancer Research
Cancer Res (2000) 60 (24): 6942–6949.
Published: 01 December 2000
View articletitled, Antibody Targeting of Doxorubicin-loaded Liposomes Suppresses the Growth and Metastatic Spread of Established Human Lung Tumor Xenografts in Severe Combined Immunodeficient Mice
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Journal Articles

In Situ Tumor Vaccination with Interleukin-12-encapsulated Biodegradable Microspheres: Induction of Tumor Regression and Potent Antitumor Immunity

Nejat K. Egilmez, Yong S. Jong, Michael S. Sabel, Jules S. Jacob, Edith Mathiowitz, Richard B. Bankert
Journal: Cancer Research
Cancer Res (2000) 60 (14): 3832–3837.
Published: 15 July 2000
View articletitled, In Situ Tumor Vaccination with Interleukin-12-encapsulated Biodegradable Microspheres: Induction of Tumor Regression and Potent Antitumor Immunity
Open the PDF for In Situ Tumor Vaccination with Interleukin-12-encapsulated Biodegradable Microspheres: Induction of Tumor Regression and Potent Antitumor Immunity in another window
Journal Articles

Antitumor Immune Response of Human Peripheral Blood Lymphocytes Coengrafted with Tumor into Severe Combined Immunodeficient Mice

Yoshimi Iwanuma, Fang-An Chen, Nejat K. Egilmez, Hiroshi Takita, Richard B. Bankert
Journal: Cancer Research
Cancer Res (1997) 57 (14): 2937–2942.
Published: 01 July 1997
View articletitled, Antitumor Immune Response of Human Peripheral Blood Lymphocytes Coengrafted with Tumor into Severe Combined Immunodeficient Mice
Open the PDF for Antitumor Immune Response of Human Peripheral Blood Lymphocytes Coengrafted with Tumor into Severe Combined Immunodeficient Mice in another window