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Neil O. Carragher
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Journal Articles

Abstract 4031: In vivo studies demonstrate differences in target inhibition and anticancer efficacy between NXP900 and dasatinib in ovarian clear cell carcinoma model

Saúl Navarro-Marchal, Carolin Temps, Iñigo Lanzagorta-Calvillo, John C. Dawson, Enrique Poradosu, Neil O. Carragher, Valerie G. Brunton, Asier Unciti-Broceta
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4031.
https://doi.org/10.1158/1538-7445.AM2023-4031
Published: 04 April 2023
View article titled, Abstract 4031: <em>In vivo</em> studies demonstrate differences in target inhibition and anticancer efficacy between NXP900 and dasatinib in ovarian clear cell carcinoma model
Journal Articles

A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability

Carolin Temps, Daniel Lietha, Emily R. Webb, Xue-Feng Li, John C. Dawson, Morwenna Muir, Kenneth G. Macleod, Teresa Valero, Alison F. Munro, Rafael Contreras-Montoya, Juan R. Luque-Ortega, Craig Fraser, Henry Beetham, Christina Schoenherr, Maria Lopalco, Mark J. Arends, Margaret C. Frame, Bin-Zhi Qian, Valerie G. Brunton, Neil O. Carragher, Asier Unciti-Broceta
Journal: Cancer Research
Cancer Res (2021) 81 (21): 5438–5450.
https://doi.org/10.1158/0008-5472.CAN-21-0613
Published: 01 November 2021
View article titled, A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability
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Includes: Supplementary data
Journal Articles

Abstract A13: Macrophage FLT1 mediated inflammatory response determines breast cancer distal metastasis

Bin-Zhi Qian, Hui Zhang, Jiufeng Li, Eun-Jin Yeo, Neil O. Carragher, Anne R. Bresnick, Richard A. Lang, Jeffrey W. Pollard
Journal: Cancer Research
Cancer Res (2016) 76 (7_Supplement): A13.
https://doi.org/10.1158/1538-7445.TUMMET15-A13
Published: 26 May 2016
View article titled, Abstract A13: Macrophage FLT1 mediated inflammatory response determines breast cancer distal metastasis
Journal Articles

Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer

Max Nobis, Ewan J. McGhee, Jennifer P. Morton, Juliane P. Schwarz, Saadia A. Karim, Jean Quinn, Mike Edward, Andrew D. Campbell, Lynn C. McGarry, T.R. Jeffry Evans, Valerie G. Brunton, Margaret C. Frame, Neil O. Carragher, Yingxiao Wang, Owen J. Sansom, Paul Timpson, Kurt I. Anderson
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (15): 4674–4686.
https://doi.org/10.1158/0008-5472.CAN-12-4545
Published: 31 July 2013
View article titled, Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer
Open the PDF for Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 4303: A high-throughput cell invasion assay combined with reverse phase protein microarrays for rational development of drug combination strategies targeting tumor invasion

John C. Dawson, Neil O. Carragher, Jennifer Fronczak, Keren Hulkower
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4303.
https://doi.org/10.1158/1538-7445.AM2012-4303
Published: 15 April 2012
View article titled, Abstract 4303: A high-throughput cell invasion assay combined with reverse phase protein microarrays for rational development of drug combination strategies targeting tumor invasion
Journal Articles

Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53

Paul Timpson, Ewan J. McGhee, Jennifer P. Morton, Alex von Kriegsheim, Juliane P. Schwarz, Saadia A. Karim, Brendan Doyle, Jean A. Quinn, Neil O. Carragher, Mike Edward, Michael F. Olson, Margaret C. Frame, Valerie G. Brunton, Owen J. Sansom, Kurt I. Anderson
Journal: Cancer Research
Cancer Res (2011) 71 (3): 747–757.
https://doi.org/10.1158/0008-5472.CAN-10-2267
Published: 01 February 2011
View article titled, Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53
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Includes: Multimedia, Supplementary data
Journal Articles

Real-time Study of E-Cadherin and Membrane Dynamics in Living Animals: Implications for Disease Modeling and Drug Development

Alan Serrels, Paul Timpson, Marta Canel, Juliane P. Schwarz, Neil O. Carragher, Margaret C. Frame, Valerie G. Brunton, Kurt I. Anderson
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2714–2719.
https://doi.org/10.1158/0008-5472.CAN-08-4308
Published: 01 April 2009
View article titled, Real-time Study of E-Cadherin and Membrane Dynamics in Living Animals: Implications for Disease Modeling and Drug Development
Open the PDF for Real-time Study of E-Cadherin and Membrane Dynamics in Living Animals: Implications for Disease Modeling and Drug Development in another window
Includes: Multimedia, Supplementary data