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Journal Articles

Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Toni M. Brand, Stefan Hartmann, Neil E. Bhola, Hua Li, Yan Zeng, Rachel A. O'Keefe, Max V. Ranall, Sourav Bandyopadhyay, Margaret Soucheray, Nevan J. Krogan, Carolyn Kemp, Umamaheswar Duvvuri, Theresa LaVallee, Daniel E. Johnson, Michelle A. Ozbun, Julie E. Bauman, Jennifer R. Grandis

Cancer Res (2022) 82 (17): 3188.

https://doi.org/10.1158/0008-5472.CAN-22-1307

Published: 02 September 2022

View article titled, Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Journal Articles

Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Cancer Res (2022) 82 (17): 3187.

https://doi.org/10.1158/0008-5472.CAN-22-1308

Published: 02 September 2022

View article titled, Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Journal Articles

Correction: Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer

Valerie M. Jansen, Neil E. Bhola, Joshua A. Bauer, Luigi Formisano, Kyung-Min Lee, Katherine E. Hutchinson, Agnieszka K. Witkiewicz, Preston D. Moore, Mónica Valéria Estrada, Violeta Sánchez, Paula G. Ericsson, Melinda E. Sanders, Paula R. Pohlmann, Michael J. Pishvaian, David A. Riddle, Teresa C. Dugger, Wenyi Wei, Erik S. Knudsen, Carlos L. Arteaga

Cancer Res (2019) 79 (4): 874.

https://doi.org/10.1158/0008-5472.CAN-18-4086

Published: 15 February 2019

View article titled, Correction: Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer

Journal Articles

Correction: Kinome-wide Functional Screen Identifies Role of PLK1 in Hormone-Independent, ER-Positive Breast Cancer

Neil E. Bhola, Valerie M. Jansen, Sangeeta Bafna, Jennifer M. Giltnane, Justin M. Balko, Mónica V. Estrada, Ingrid Meszoely, Ingrid Mayer, Vandana Abramson, Fei Ye, Melinda Sanders, Teresa C. Dugger, Eliezer V. Allen, Carlos L. Arteaga

Cancer Res (2019) 79 (4): 876.

https://doi.org/10.1158/0008-5472.CAN-18-4088

Published: 15 February 2019

View article titled, Correction: Kinome-wide Functional Screen Identifies Role of PLK1 in Hormone-Independent, ER-Positive Breast Cancer

Journal Articles

Correction: Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Neil E. Bhola, Valerie M. Jansen, James P. Koch, Hua Li, Luigi Formisano, Janice A. Williams, Jennifer R. Grandis, Carlos L. Arteaga

Cancer Res (2019) 79 (4): 875.

https://doi.org/10.1158/0008-5472.CAN-18-4087

Published: 15 February 2019

View article titled, Correction: Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Journal Articles

BET Inhibition Overcomes Receptor Tyrosine Kinase–Mediated Cetuximab Resistance in HNSCC

Brandon Leonard, Toni M. Brand, Rachel A. O'Keefe, Eliot D. Lee, Yan Zeng, Jacquelyn D. Kemmer, Hua Li, Jennifer R. Grandis, Neil E. Bhola

Cancer Res (2018) 78 (15): 4331–4343.

https://doi.org/10.1158/0008-5472.CAN-18-0459

Published: 31 July 2018

View article titled, BET Inhibition Overcomes Receptor Tyrosine Kinase–Mediated Cetuximab Resistance in HNSCC

Includes: Supplementary data

Journal Articles

Abstract 1972: Targeting the IL-6 signaling pathway overcomes cetuximab resistance in head and neck squamous cell carcinoma

Rachel A. O'Keefe, Neil E. Bhola, David S. Lee, Daniel E. Johnson, Jennifer R. Grandis

Cancer Res (2018) 78 (13_Supplement): 1972.

https://doi.org/10.1158/1538-7445.AM2018-1972

Published: 01 July 2018

View article titled, Abstract 1972: Targeting the IL-6 signaling pathway overcomes cetuximab resistance in head and neck squamous cell carcinoma

Journal Articles

Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Cancer Res (2018) 78 (9): 2383–2395.

https://doi.org/10.1158/0008-5472.CAN-17-1672

Published: 30 April 2018

View article titled, Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Includes: Supplementary data

Journal Articles

Abstract 95: Targeting BRD4 overcomes cetuximab resistance in HNSCC

Toni Brand, Yan Zeng, Brandon Leonard, Rachel O' Keefe, Hua Li, Daniel Johnson, Jennifer Grandis, Neil E. Bhola

Cancer Res (2017) 77 (13_Supplement): 95.

https://doi.org/10.1158/1538-7445.AM2017-95

Published: 01 July 2017

View article titled, Abstract 95: Targeting BRD4 overcomes cetuximab resistance in HNSCC

Journal Articles

Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer

Cancer Res (2017) 77 (9): 2488–2499.

https://doi.org/10.1158/0008-5472.CAN-16-2653

Published: 30 April 2017

View article titled, Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer

Includes: Supplementary data

Journal Articles

Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Neil E. Bhola, Valerie M. Jansen, James P. Koch, Hua Li, Luigi Formisano, Janice A. Williams, Jennifer R. Grandis, Carlos L. Arteaga

Cancer Res (2016) 76 (2): 440–452.

https://doi.org/10.1158/0008-5472.CAN-15-1640-T

Published: 14 January 2016

View article titled, Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Includes: Supplementary data

Journal Articles

Abstract 4240: TORC inhibition enriches for a cancer stem cell-like population with FGFR-dependent Notch1 activation

Neil E. Bhola, Valerie M. Jansen, Carlos L. Arteaga

Cancer Res (2015) 75 (15_Supplement): 4240.

https://doi.org/10.1158/1538-7445.AM2015-4240

Published: 01 August 2015

View article titled, Abstract 4240: TORC inhibition enriches for a cancer stem cell-like population with FGFR-dependent Notch1 activation

Journal Articles

Abstract 2844: RNA interference kinome-wide screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition ER-positive breast cancer

Valerie M. Jansen, Neil E. Bhola, Joshua A. Bauer, Carlos L. Arteaga

Cancer Res (2015) 75 (15_Supplement): 2844.

https://doi.org/10.1158/1538-7445.AM2015-2844

Published: 01 August 2015

View article titled, Abstract 2844: RNA interference kinome-wide screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition ER-positive breast cancer

Journal Articles

Kinome-wide Functional Screen Identifies Role of PLK1 in Hormone-Independent, ER-Positive Breast Cancer

Cancer Res (2015) 75 (2): 405–414.

https://doi.org/10.1158/0008-5472.CAN-14-2475

Published: 14 January 2015

View article titled, Kinome-wide Functional Screen Identifies Role of PLK1 in Hormone-Independent, ER-Positive Breast Cancer

Includes: Supplementary data

Journal Articles

Abstract 1945: TORC inhibitors increase the cancer stem cell (CSC) population and Notch signaling in triple negative breast cancer

Neil E. Bhola, Valerie Jansen, Carlos Arteaga

Cancer Res (2014) 74 (19_Supplement): 1945.

https://doi.org/10.1158/1538-7445.AM2014-1945

Published: 01 October 2014

View article titled, Abstract 1945: TORC inhibitors increase the cancer stem cell (CSC) population and Notch signaling in triple negative breast cancer

Journal Articles

Abstract 970: Mass spectrometry analysis of PIK3CA mutant mammary epithelial cells identifies EGFR as a paracrine effector of PI3K in basal-like breast cancer

Christian D. Young, Lisa J. Zimmerman, Michael L. Gatza, Meghan M. Morrison, Corbin A. Whitwell, Neil E. Bhola, Ariella B. Hanker, Thomas Stricker, Premal Patel, Dana M. Brantley-Sieders, Charles M. Perou, Ben H. Park, Daniel C. Liebler, Rebecca S. Cook, Carlos L. Arteaga

Cancer Res (2014) 74 (19_Supplement): 970.

https://doi.org/10.1158/1538-7445.AM2014-970

Published: 01 October 2014

View article titled, Abstract 970: Mass spectrometry analysis of PIK3CA mutant mammary epithelial cells identifies EGFR as a paracrine effector of PI3K in basal-like breast cancer

Journal Articles

Activation of MAPK Pathways due to DUSP4 Loss Promotes Cancer Stem Cell-like Phenotypes in Basal-like Breast Cancer

Justin M. Balko, Luis J. Schwarz, Neil E. Bhola, Richard Kurupi, Phillip Owens, Todd W. Miller, Henry Gómez, Rebecca S. Cook, Carlos L. Arteaga

Cancer Res (2013) 73 (20): 6346–6358.

https://doi.org/10.1158/0008-5472.CAN-13-1385

Published: 14 October 2013

View article titled, Activation of MAPK Pathways due to DUSP4 Loss Promotes Cancer Stem Cell-like Phenotypes in Basal-like Breast Cancer

Includes: Supplementary data

Journal Articles

Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors

Anindita Chakrabarty, Neil E. Bhola, Cammie Sutton, Ritwik Ghosh, María Gabriela Kuba, Bhuvanesh Dave, Jenny C. Chang, Carlos L. Arteaga

Cancer Res (2013) 73 (3): 1190–1200.

https://doi.org/10.1158/0008-5472.CAN-12-2440

Published: 31 January 2013

View article titled, Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors

Includes: Supplementary data

Journal Articles

Abstract 3475: Inhibition of the TGFβ pathway inhibits chemotherapy-induced enrichment of breast cancer stem cells in triple-negative breast cancer

Neil E. Bhola, Justin Balko, Carlos Arteaga

Cancer Res (2012) 72 (8_Supplement): 3475.

https://doi.org/10.1158/1538-7445.AM2012-3475

Published: 15 April 2012

View article titled, Abstract 3475: Inhibition of the TGFβ pathway inhibits chemotherapy-induced enrichment of breast cancer stem cells in triple-negative breast cancer

Journal Articles

Cross-talk between G Protein–Coupled Receptor and Epidermal Growth Factor Receptor Signaling Pathways Contributes to Growth and Invasion of Head and Neck Squamous Cell Carcinoma

Sufi Mary Thomas, Neil E. Bhola, Qing Zhang, Sarah C. Contrucci, Abbey L. Wentzel, Maria L. Freilino, William E. Gooding, Jill M. Siegfried, Daniel C. Chan, Jennifer Rubin Grandis

Cancer Res (2006) 66 (24): 11831–11839.

https://doi.org/10.1158/0008-5472.CAN-06-2876

Published: 18 December 2006

View article titled, Cross-talk between G Protein–Coupled Receptor and Epidermal Growth Factor Receptor Signaling Pathways Contributes to Growth and Invasion of Head and Neck Squamous Cell Carcinoma

NARROW

Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Correction: Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer

Correction: Kinome-wide Functional Screen Identifies Role of PLK1 in Hormone-Independent, ER-Positive Breast Cancer

Correction: Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

BET Inhibition Overcomes Receptor Tyrosine Kinase–Mediated Cetuximab Resistance in HNSCC

Abstract 1972: Targeting the IL-6 signaling pathway overcomes cetuximab resistance in head and neck squamous cell carcinoma

Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Abstract 95: Targeting BRD4 overcomes cetuximab resistance in HNSCC

Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer

Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Abstract 4240: TORC inhibition enriches for a cancer stem cell-like population with FGFR-dependent Notch1 activation

Abstract 2844: RNA interference kinome-wide screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition ER-positive breast cancer

Kinome-wide Functional Screen Identifies Role of PLK1 in Hormone-Independent, ER-Positive Breast Cancer

Abstract 1945: TORC inhibitors increase the cancer stem cell (CSC) population and Notch signaling in triple negative breast cancer

Abstract 970: Mass spectrometry analysis of PIK3CA mutant mammary epithelial cells identifies EGFR as a paracrine effector of PI3K in basal-like breast cancer

Activation of MAPK Pathways due to DUSP4 Loss Promotes Cancer Stem Cell-like Phenotypes in Basal-like Breast Cancer

Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors

Abstract 3475: Inhibition of the TGFβ pathway inhibits chemotherapy-induced enrichment of breast cancer stem cells in triple-negative breast cancer

Cross-talk between G Protein–Coupled Receptor and Epidermal Growth Factor Receptor Signaling Pathways Contributes to Growth and Invasion of Head and Neck Squamous Cell Carcinoma

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