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Neeta Somaiah
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Journal Articles

Abstract 5486: Spatial profiling reveals unique immune-transcriptomic features of tertiary lymphoid structures in melanoma

Manoj Chelvanambi, Brenda Melendez, Elise F. Nassif, Rossana N. Lazcano, Matthew J. Lastrapes, Bharat S. Bhushan, Sarah B. Johnson, Khalida Wani, Davis R. Ingram, Y David Seo, Beth A. Helmink, Michael G. White, Russell G. Witt, Laurence P. Diggs, Golnaz Morad, Monika Zelazowska, Somnath Paul, Florentia Dimitriou, Ashish V. Damania, Matthew C. Wong, Neeta Somaiah, Nadim J. Ajami, Emily Z. Keung, Wolf H. Fridman, James P. Allison, Padmanee Sharma, Kevin M. McBride, Tina Cascone, Christina L. Roland, Alexander J. Lazar, Jennifer A. Wargo
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5486.
https://doi.org/10.1158/1538-7445.AM2024-5486
Published: 22 March 2024
View article titled, Abstract 5486: Spatial profiling reveals unique immune-transcriptomic features of tertiary lymphoid structures in melanoma
Journal Articles

Abstract 3858: Peripheral CD38+ effector memory (EM) T cells are dynamic biomarkers of response to neoadjuvant immune checkpoint blockade (NeoICB) in patients (pts) with resectable dedifferentiated liposarcoma (DDLPS) and undifferentiated pleomorphic sarcoma (UPS)

Elise F. Nassif, Hsinyi Lu, Michael Stanford, Karen Millerchip, Diana Romero, Jared Malke, Brenna Matejka, Jeffrey E. Gershenwald, Susmita Kumari, Duncan H. Mak, Angelique J. Lin, Jared K. Burks, Wei-Lien Wang, Alexander J. Lazar, Neeta Somaiah, Cara Haymaker, Christina L. Roland, Emily Z. Keung
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3858.
https://doi.org/10.1158/1538-7445.AM2024-3858
Published: 22 March 2024
View article titled, Abstract 3858: Peripheral CD38+ effector memory (EM) T cells are dynamic biomarkers of response to neoadjuvant immune checkpoint blockade (NeoICB) in patients (pts) with resectable dedifferentiated liposarcoma (DDLPS) and undifferentiated pleomorphic sarcoma (UPS)
Journal Articles

Abstract 6558: Defining differentiation States in well-differentiated and de-differentiated liposarcoma

Danh Truong, Hannah C. Beird, Chia-Chin Wu, Sandhya Krishnan, Davis Ingram, Alexander Lazar, Emily Keung, Christina Roland, Wantong Yao, Robert Benjamin, Neeta Somaiah, Barry W. Feig, Joseph A. Ludwig
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6558.
https://doi.org/10.1158/1538-7445.AM2023-6558
Published: 04 April 2023
View article titled, Abstract 6558: Defining differentiation States in well-differentiated and de-differentiated liposarcoma
Journal Articles

Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time

Tuyen Duong Thanh Nguyen, Yan Wang, Tuyen N. Bui, Rossana Lazcano, Davis R. Ingram, Min Yi, Varshini Vakulabharanam, Linjie Luo, Marc A. Pina, Cansu Karakas, Mi Li, Nicole M. Kettner, Neeta Somaiah, Peter J. Hougton, Osama Mawlawi, Alexander J. Lazar, Kelly K. Hunt, Khandan Keyomarsi
Journal: Cancer Research
Cancer Res (2023) 83 (6): 939–955.
https://doi.org/10.1158/0008-5472.CAN-22-2258
Published: 15 March 2023
View article titled, Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Open the PDF for Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time in another window
Includes: Supplementary data
Journal Articles

Abstract CT123: Population pharmacokinetics of ripretinib in patients with advanced malignancies

Suzanne George, Filip Janku, Ping Chi, Margaret von Mehren, Neeta Somaiah, Hans Gelderblom, Robin L. Jones, Martine Allard, Adekemi Taylor, Xiaoyan Li, Julie Meade, Vienna Reichert, Rodrigo Ruiz-Soto, Jing Wang, Michael C. Heinrich
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT123.
https://doi.org/10.1158/1538-7445.AM2021-CT123
Published: 01 July 2021
View article titled, Abstract CT123: Population pharmacokinetics of ripretinib in patients with advanced malignancies
Journal Articles

Abstract LB057: Whole exome sequencing of tumor tissue and circulating tumor DNA ingastrointestinal stromal tumors (GIST)

Niamh Coleman, Charles Abbot, Neeta Somaiah, Sarina Piha-Paul, Shubham Pant, Jordi Rodon, S. Greg Call, Sean Boyle, Funda Meric-Bernstam, Filip Janku
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB057.
https://doi.org/10.1158/1538-7445.AM2021-LB057
Published: 01 July 2021
View article titled, Abstract LB057: Whole exome sequencing of tumor tissue and circulating tumor DNA ingastrointestinal stromal tumors (GIST)
Journal Articles

Abstract 518: Immunogenomic correlates of response to combination immune checkpoint blockade in advanced sarcoma

Akash Mitra, Neeta Somaiah, Anthony P. Conley, Behrang Amini, Heather Lin, Beatriz E. Sanchez, Celia Garcia-Prieto, Grace Mathew, Chantale Bernatchez, Vinod Ravi, Dejka Araujo, Maria A. Zarzour, John A. Livingston, Christina L. Roland, Najat Daw, Joshua Baguley, Wei-Lien Wang, Hannah Beird, Taylor Tate, Cara Haymaker, Latasha D. Little, Curtis Gumbs, Xingshi Song, Emily Z. Keung, Shaojun Zhang, Swati Gite, Jianhua Zhang, Luisa Solis, Hussein Tawbi, Linghua Wang, Shreyaskumar Patel, Robert S. Benjamin, Alexander J. Lazar, Ignacio I. Wistuba, Andrew Futreal
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 518.
https://doi.org/10.1158/1538-7445.AM2021-518
Published: 01 July 2021
View article titled, Abstract 518: Immunogenomic correlates of response to combination immune checkpoint blockade in advanced sarcoma
Journal Articles

Abstract CT150: A first-in-human phase I study of the OX40 agonist GSK3174998 (GSK998) +/- pembrolizumab in patients (Pts) with selected advanced solid tumors (ENGAGE-1)

Sophie Postel-Vinay, Vincent K. Lam, Willeke Ros, Todd M. Bauer, Aaron R. Hansen, Daniel C. Cho, F. Stephen Hodi, Jan H.M. Schellens, Jennifer K. Litton, Sandrine Aspeslagh, Karen A. Autio, Frans L. Opdam, Meredith McKean, Neeta Somaiah, Stephane Champiat, Mehmet Altan, Anna Spreafico, Osama Rahma, Elaine M. Paul, Christoph M. Ahlers, Helen Zhou, Herbert Struemper, Shelby A. Gorman, Maura Watmuff, Kaitlin M. Yablonski, Niranjan Yanamandra, Michael J. Chisamore, Emmett V. Schmidt, Axel Hoos, Aurélien Marabelle, Jeffrey S. Weber, John V. Heymach
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT150.
https://doi.org/10.1158/1538-7445.AM2020-CT150
Published: 15 August 2020
View article titled, Abstract CT150: A first-in-human phase I study of the OX40 agonist GSK3174998 (GSK998) +/- pembrolizumab in patients (Pts) with selected advanced solid tumors (ENGAGE-1)
Journal Articles

Abstract 1107: Cell-surface vimentin-positive macrophages like CTCs as novel biomarkers of metastatic gastrointestinal stromal tumors

Heming Li, Qing H. Meng, Hyangsoon Noh, Neeta Somaiah, Keila E. Torres, Xueqing Xia, Izhar Singh Batth, Cissimol P. Joseph, Zachary A. Mulder, Ruoyu Wang, Shulin Li
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1107.
https://doi.org/10.1158/1538-7445.AM2018-1107
Published: 01 July 2018
View article titled, Abstract 1107: Cell-surface vimentin-positive macrophages like CTCs as novel biomarkers of metastatic gastrointestinal stromal tumors
Journal Articles

Abstract CT029: Pharmacokinetic (PK), safety, and tolerability profile of DCC-2618 in a phase I trial supports 150mg QD selected for a pivotal phase III trial in gastrointestinal stromal tumor (GIST)

Filip Janku, Michael Heinrich, Albiruni Razak, Michael Gordon, Ping Chi, Kristen Ganjoo, Margaret von Mehren, Neeta Somaiah, Jongtae Lee, Keisuke Kuida, Rodrigo Ruiz Soto, Oliver Rosen, Suzanne George
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT029.
https://doi.org/10.1158/1538-7445.AM2018-CT029
Published: 01 July 2018
View article titled, Abstract CT029: Pharmacokinetic (PK), safety, and tolerability profile of DCC-2618 in a phase I trial supports 150mg QD selected for a pivotal phase III trial in gastrointestinal stromal tumor (GIST)
Journal Articles

Abstract LB-039: Translational research in a phase I proof-of-concept study supports that DCC-2618 is a pan-KIT inhibitor

Filip Janku, Albi Razak, Michael Gordon, David Brooks, Daniel Flynn, Anu Gupta, Michael Kaufman, Cynthia Leary, Bryan Smith, Deb Westwood, Neeta Somaiah, Elena Helman, Eric Gerstenberger, Oliver Rosen, Suzanne George
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-039.
https://doi.org/10.1158/1538-7445.AM2017-LB-039
Published: 01 July 2017
View article titled, Abstract LB-039: Translational research in a phase I proof-of-concept study supports that DCC-2618 is a pan-KIT inhibitor
Journal Articles

Abstract 1931: The first circulating tumor cell detection technique from frozen PBMCs

Heming Li, Izhar Singh Batth, Xueqing Xia, Frank J. Hsu, Neeta Somaiah, Keila Enitt Torres, Ruoyu Wang, Shulin Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1931.
https://doi.org/10.1158/1538-7445.AM2017-1931
Published: 01 July 2017
View article titled, Abstract 1931: The first circulating tumor cell detection technique from frozen PBMCs
Journal Articles

Abstract 4573: Characteristics and outcomes of patients with advanced sarcoma enrolled in early phase immunotherapy trials

Roman Groisberg, Vivek Subbiah, David Hong, Filip Janku, Sarina Piha-Paul, Aung Naing, Robert Benjamin, Shreyas Kumar Putal, Neeta Somaiah, Anthony Conley
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4573.
https://doi.org/10.1158/1538-7445.AM2017-4573
Published: 01 July 2017
View article titled, Abstract 4573: Characteristics and outcomes of patients with advanced sarcoma enrolled in early phase immunotherapy trials
Journal Articles

Universal Marker and Detection Tool for Human Sarcoma Circulating Tumor Cells

Arun Satelli, Abhisek Mitra, Jeffry J. Cutrera, Marcos Devarie, Xueqing Xia, Davis R. Ingram, Denada Dibra, Neeta Somaiah, Keila E. Torres, Vinod Ravi, Joseph A. Ludwig, Eugenie S. Kleinerman, Shulin Li
Journal: Cancer Research
Cancer Res (2014) 74 (6): 1645–1650.
https://doi.org/10.1158/0008-5472.CAN-13-1739
Published: 13 March 2014
View article titled, Universal Marker and Detection Tool for Human Sarcoma Circulating Tumor Cells
Open the PDF for Universal Marker and Detection Tool for Human Sarcoma Circulating Tumor Cells in another window
Includes: Supplementary data