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Nathalie Bonnefoy
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Journal Articles

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer

Eve Combès, Augusto F. Andrade, Diego Tosi, Henri-Alexandre Michaud, Flavie Coquel, Veronique Garambois, Delphine Desigaud, Marta Jarlier, Arnaud Coquelle, Philippe Pasero, Nathalie Bonnefoy, Jerome Moreaux, Pierre Martineau, Maguy Del Rio, Roderick L. Beijersbergen, Nadia Vezzio-Vie, Celine Gongora
Journal: Cancer Research
Cancer Res (2019) 79 (11): 2933–2946.
https://doi.org/10.1158/0008-5472.CAN-18-2807
Published: 03 June 2019
View article titled, Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (<em>ATR</em>) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer
Open the PDF for Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (<em>ATR</em>) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2718: Preclinical development of humanized CD39 and CD73 blocking antibodies targeting the ATP/adenosine immune checkpoint pathway for cancer immunotherapy

Ivan Perrot, Marc Giraudon Paoli, Séverine Augier, Marilyne Royannez Blemont, Marion Gaudin, Frédéric Bosco, Rachel Courtois, Stephane Delahaye, Diana Jecko, Nicolas Gourdin, Maryline Salin Agu, Cyril Perrier, Paul Ricaut, Aurélie Docquier, Stéphanie Chanteux, Benjamin Rossi, Agnès Représa, Caroline Denis, Romain Remark, Cécile Bonnafous, Laurent Gauthier, Ariane Morel, Nathalie Bonnefoy, Jérémy Bastid, Yannis Morel, Carine Paturel
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2718.
https://doi.org/10.1158/1538-7445.AM2018-2718
Published: 01 July 2018
View article titled, Abstract 2718: Preclinical development of humanized CD39 and CD73 blocking antibodies targeting the ATP/adenosine immune checkpoint pathway for cancer immunotherapy
Journal Articles

Abstract 1602: Generation of anti-IL-17B antibodies neutralizing IL-17B-mediated alterations of the immune microenvironment, promotion of tumor cell initiating capacity and chemoresistance

Emilie Laprevotte, Aurélie Docquier, Jeremy Bastid, Cécile Déjou, Marion Lapierre, Gilles Alberici, Armand Bensussan, Jean-François Eliaou, Nathalie Bonnefoy
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1602.
https://doi.org/10.1158/1538-7445.AM2017-1602
Published: 01 July 2017
View article titled, Abstract 1602: Generation of anti-IL-17B antibodies neutralizing IL-17B-mediated alterations of the immune microenvironment, promotion of tumor cell initiating capacity and chemoresistance
Journal Articles

Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX–Bevacizumab Drug Treatment Regimen

Emeric Limagne, Romain Euvrard, Marion Thibaudin, Cédric Rébé, Valentin Derangère, Angélique Chevriaux, Romain Boidot, Frédérique Végran, Nathalie Bonnefoy, Julie Vincent, Leila Bengrine-Lefevre, Sylvain Ladoire, Dominique Delmas, Lionel Apetoh, François Ghiringhelli
Journal: Cancer Research
Cancer Res (2016) 76 (18): 5241–5252.
https://doi.org/10.1158/0008-5472.CAN-15-3164
Published: 15 September 2016
View article titled, Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX–Bevacizumab Drug Treatment Regimen
Open the PDF for Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX–Bevacizumab Drug Treatment Regimen in another window
Includes: Supplementary data
Journal Articles

Abstract 3222: Preclinical development of a humanized blocking antibody targeting the CD39 immune checkpoint for cancer immunotherapy

Severine Augier, Ivan Perrot, Cecile Dejou, Rachel Joly, Stephane Delahaye, Helene Rispaud Blanc, Caroline Denis, Laurent Gauthier, Armand Bensussan, Jean-francois Eliaou, Yannis Morel, Nathalie Bonnefoy, Jeremy Bastid, Carine Paturel
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3222.
https://doi.org/10.1158/1538-7445.AM2016-3222
Published: 15 July 2016
View article titled, Abstract 3222: Preclinical development of a humanized blocking antibody targeting the CD39 immune checkpoint for cancer immunotherapy
Journal Articles

Abstract 3218: Disruption of the CD39 immune checkpoint pathway increases the efficacy of various anticancer therapies in syngeneic mouse models

Marion Lapierre, Cécile Dejou, Carine Paturel, Henri-Alexandre Michaud, Laurent Gros, Armand Bensussan, Jean-François Eliaou, Jeremy Bastid, Nathalie Bonnefoy
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3218.
https://doi.org/10.1158/1538-7445.AM2016-3218
Published: 15 July 2016
View article titled, Abstract 3218: Disruption of the CD39 immune checkpoint pathway increases the efficacy of various anticancer therapies in syngeneic mouse models
Journal Articles

Abstract 5027: Interleukin-17B promotes chemoresistance of breast tumors through ERK1/2 anti-apoptotic pathway

Emilie Laprevotte, Jeremy Bastid, Stéphanie Cochaud, Jerôme Giustiniani, Marion Philippe, Kathryn A. Frewer, Andrew J. Sanders, Wen G. Jiang, Armand Bensussan, Gilles Alberici, Jean-François Eliaou, Nathalie Bonnefoy
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5027.
https://doi.org/10.1158/1538-7445.AM2015-5027
Published: 01 August 2015
View article titled, Abstract 5027: Interleukin-17B promotes chemoresistance of breast tumors through ERK1/2 anti-apoptotic pathway
Journal Articles

Abstract 3171: IL-25/IL-17E does not induce breast tumor cell apoptosis and both IL-17A and IL-25/IL-17E contribute to breast cancer survival and proliferation associated with generation of pro-oncogenic low molecular forms of cyclin E

Jérôme Giustiniani, Hervé Curé, Christian Garbar, Yacine Merrouche, Nathalie Bonnefoy, Jérémy Bastid, Gilles Alberici, Jean-François Eliaou, Armand Bensussan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3171.
https://doi.org/10.1158/1538-7445.AM2015-3171
Published: 01 August 2015
View article titled, Abstract 3171: IL-25/IL-17E does not induce breast tumor cell apoptosis and both IL-17A and IL-25/IL-17E contribute to breast cancer survival and proliferation associated with generation of pro-oncogenic low molecular forms of cyclin E
Journal Articles

Abstract 5036: Blockade of the CD39 immunoregulatory pathway by monoclonal antibodies

Jeremy Bastid, Cécile Dejou, Jérôme Giustiniani, Stéphanie Cochaud, Gilles Alberici, Armand Bensussan, Jean-François Eliaou, Nathalie Bonnefoy
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5036.
https://doi.org/10.1158/1538-7445.AM2014-5036
Published: 01 October 2014
View article titled, Abstract 5036: Blockade of the CD39 immunoregulatory pathway by monoclonal antibodies
Journal Articles

Abstract B3: CD39+ cancer cells mediate immunosuppression reverted by CD39-blocking antibodies.

Anne Regairaz, Caroline Laheurte, Nathalie Bonnefoy, Jean-Francois Eliaou, Gilles Alberici, Armand Bensussan, Jeremy Bastid
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): B3.
https://doi.org/10.1158/1538-7445.TUMIMM2012-B3
Published: 02 April 2014
View article titled, Abstract B3: CD39+ cancer cells mediate immunosuppression reverted by CD39-blocking antibodies.
Journal Articles

Anthracyclines Trigger Apoptosis of Both G0-G1 and Cycling Peripheral Blood Lymphocytes and Induce Massive Deletion of Mature T and B Cells

Carole Ferraro, Laurence Quemeneur, Annie-France Prigent, Catherine Taverne, Jean-Pierre Revillard, Nathalie Bonnefoy-Berard
Journal: Cancer Research
Cancer Res (2000) 60 (7): 1901–1907.
Published: 01 April 2000
View article titled, Anthracyclines Trigger Apoptosis of Both G<sub>0</sub>-G<sub>1</sub> and Cycling Peripheral Blood Lymphocytes and Induce Massive Deletion of Mature T and B Cells
Open the PDF for Anthracyclines Trigger Apoptosis of Both G<sub>0</sub>-G<sub>1</sub> and Cycling Peripheral Blood Lymphocytes and Induce Massive Deletion of Mature T and B Cells in another window