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Natasha Sahgal
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Journal Articles

Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response

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Ping Zhang, Isaac Kitchen-Smith, Lingyun Xiong, Giovanni Stracquadanio, Katherine Brown, Philipp H. Richter, Marsha D. Wallace, Elisabeth Bond, Natasha Sahgal, Samantha Moore, Svanhild Nornes, Sarah De Val, Mirvat Surakhy, David Sims, Xuting Wang, Douglas A. Bell, Jorge Zeron-Medina, Yanyan Jiang, Anderson J. Ryan, Joanna L. Selfe, Janet Shipley, Siddhartha Kar, Paul D. Pharoah, Chey Loveday, Rick Jansen, Lukasz F. Grochola, Claire Palles, Andrew Protheroe, Val Millar, Daniel V. Ebner, Meghana Pagadala, Sarah P. Blagden, Timothy S. Maughan, Enric Domingo, Ian Tomlinson, Clare Turnbull, Hannah Carter, Gareth L. Bond
Journal: Cancer Research
Cancer Res (2021) 81 (7): 1667–1680.
https://doi.org/10.1158/0008-5472.CAN-20-0177
Published: 01 April 2021
View articletitled, Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response
Open the PDF for Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response in another window
Includes: Supplementary data
Journal Articles

Abstract 104: miRNAs in the 14q32 cluster are involved in lapatinib resistance

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Juliette Chupin, Ai Nagano, Victoria Haley, Catherine Lenihan, Francesca Cavicchioli, Karen O’Leary, Natasha Sahgal, Cristiana Lo Nigro, Alice Shia, Claude Chelala, Peter Schmid
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 104.
https://doi.org/10.1158/1538-7445.AM2017-104
Published: 01 July 2017
View articletitled, Abstract 104: miRNAs in the 14q32 cluster are involved in lapatinib resistance
Journal Articles

Abstract 1981: Histone demethyalase JMJD1A promotes the DNA damage response of prostate cancer cells

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Lingling Fan, Guihong Peng, Natasha Sahgal, Ladan Fazli, Martin Gleave, Yuji Zhang, Arif Hussain, Feyruz Rassool, Jianfei Qi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1981.
https://doi.org/10.1158/1538-7445.AM2016-1981
Published: 15 July 2016
View articletitled, Abstract 1981: Histone demethyalase JMJD1A promotes the DNA damage response of prostate cancer cells
Journal Articles

Abstract LB-075: The histone demethylase JMJD1A is essential to prostate cancer cells through regulation of c-Myc expression

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Lingling Fan, Guihong Peng, Natasha Sahgal, Ladan Fazli, Martin Gleave, Yuji Zhang, Arif Hussain, Jianfei Qi
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-075.
https://doi.org/10.1158/1538-7445.AM2015-LB-075
Published: 01 August 2015
View articletitled, Abstract LB-075: The histone demethylase JMJD1A is essential to prostate cancer cells through regulation of c-Myc expression
Journal Articles

Abstract 5456: The E3 ubiquitin ligase Siah2 regulates the androgen receptor activity and contributes to castration-resistant prostate cancer.

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Jianfei Qi, Manisha Tripathi, Natasha Sahgal, Ladan Fazil, Susan Ettinger, William J. Placzek, Giuseppina Claps, Leland W.K. Chung, David Bowtell, Martin Gleave, Neil Bhowmick, Ze'ev Ronai
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5456.
https://doi.org/10.1158/1538-7445.AM2013-5456
Published: 15 April 2013
View articletitled, Abstract 5456: The E3 ubiquitin ligase Siah2 regulates the androgen receptor activity and contributes to castration-resistant prostate cancer.