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Natalia Jura
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Journal Articles

Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers

Free
Adam J. Wolpaw, Richard Bayliss, Gabriele Büchel, Chi V. Dang, Martin Eilers, W. Clay Gustafson, Gwenn H. Hansen, Natalia Jura, Stefan Knapp, Mark A. Lemmon, David Levens, John M. Maris, Ronen Marmorstein, Steven J. Metallo, Julie R. Park, Linda Z. Penn, Michael Rape, Martine F. Roussel, Kevan M. Shokat, William P. Tansey, Kliment A. Verba, Seychelle M. Vos, William A. Weiss, Elmar Wolf, Yaël P. Mossé
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (7): 1627–1632.
https://doi.org/10.1158/0008-5472.CAN-20-3108
Published: 01 April 2021
View articletitled, Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers
Open the PDF for Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers in another window
Journal Articles

Abstract 223: Using physical, genetic and integrated cancer cell maps to investigate head and neck cancer and breast cancer

Free
Jason F. Kreisberg, Fan Zheng, Samson Fong, Brent M. Kuenzi, Kyle Ford, Danielle Swaney, Minkyu Kim, Jisoo Park, Zhiyong Wang, Dexter Pratt, Natalia Jura, Silvio Gutkind, Prashant Mali, Nevan Krogan, Trey Ideker
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 223.
https://doi.org/10.1158/1538-7445.AM2020-223
Published: 15 August 2020
View articletitled, Abstract 223: Using physical, genetic and integrated cancer cell maps to investigate head and neck cancer and breast cancer
Journal Articles

Abstract 1896: Patient-derived HER3 mutations transform ER+ and HER2+ breast cancer cells via MAPK pathway activation

Free
Rosalin Mishra, Samar Alanazi, Long Yuan, Thomas Solomon, Tarjani M. Thaker, Natalia Jura, Joan T. Garrett
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1896.
https://doi.org/10.1158/1538-7445.AM2018-1896
Published: 01 July 2018
View articletitled, Abstract 1896: Patient-derived HER3 mutations transform ER+ and HER2+ breast cancer cells via MAPK pathway activation
Journal Articles

Abstract 4590: Mechanism of PI3K activation by the HER3/ErbB3 receptor

Free
Nicole Michael, Michael Hopkins, Natalia Jura
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4590.
https://doi.org/10.1158/1538-7445.AM2016-4590
Published: 15 July 2016
View articletitled, Abstract 4590: Mechanism of PI3K activation by the HER3/ErbB3 receptor
Journal Articles

Abstract #3816: Insights into the activation mechanism of EGF receptor from the structure of the inactive kinase domain dimer

Free
Natalia Jura, Nicholas Endres, Kate Engel, Sebastian Deindl, Xuewu Zhang, John Kuriyan
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3816.
Published: 01 May 2009
View articletitled, Abstract #3816: Insights into the activation mechanism of EGF receptor from the structure of the inactive kinase domain dimer