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Natalia Baran
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Journal Articles

Abstract 3455: Transcriptional and phenotypic heterogeneity underpinning venetoclax resistance

Vakul Mohanty, Natalia Baran, Yuefan Huang, Shan He, Ramiz Iqbal, CTD2 consortium, Jeffrey Tyner, Gordon Mills, Marina Konopleva, Ken Chen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3455.
https://doi.org/10.1158/1538-7445.AM2023-3455
Published: 04 April 2023
View article titled, Abstract 3455: Transcriptional and phenotypic heterogeneity underpinning venetoclax resistance
Journal Articles

Abstract 5927: Leveraging single cell RNA profiling to uncover intra-tumor heterogeneity across cytogenetic subgroups in acute myeloid leukemia

Bofei Wang, Christopher Ly, Fatima Zahra Jelloul, Enes Dasdemir, Guilin Tang, Sonali Jindal, Yulong Chen, Sreyashi Basu, Poonam Desai, Pamella Borges, Preethi Gunaratne, Natalia Baran, Qing Deng, Dapeng Hao, Sean Post, Michael Green Green, Marina Konopleva, Andy Futreal, Padmanee Sharma, Hussein A. Abbas
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5927.
https://doi.org/10.1158/1538-7445.AM2023-5927
Published: 04 April 2023
View article titled, Abstract 5927: Leveraging single cell RNA profiling to uncover intra-tumor heterogeneity across cytogenetic subgroups in acute myeloid leukemia
Journal Articles

Abstract 6314: Novel granzyme B-based fusion constructs targeting FRα on liquid and solid tumors

Ana Alvarez-Cienfuegos, Lawrence H. Cheung, Khalid A. Mohamedali, Natalia Baran, Marina Konopleva, Michael G. Rosenblum
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6314.
https://doi.org/10.1158/1538-7445.AM2023-6314
Published: 04 April 2023
View article titled, Abstract 6314: Novel granzyme B-based fusion constructs targeting FRα on liquid and solid tumors
Journal Articles

Abstract 3860: ERK1/2 inhibition overcomes resistance to venetoclax in AML by altering mitochondrial metabolism

Priyanka Sharma, Lauren Ostermann, Sujan Piya, Natalia Baran, Anudishi Tyagi, Christopher Hindley, Kim-Hien Dao, Martin Sims, V. Lokesh Battula, Michael Andreeff, Gautam Borthakur
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3860.
https://doi.org/10.1158/1538-7445.AM2023-3860
Published: 04 April 2023
View article titled, Abstract 3860: ERK1/2 inhibition overcomes resistance to venetoclax in AML by altering mitochondrial metabolism
Journal Articles

Abstract 3785: ME-344, a novel isoflavone mitochondrial inhibitor, in combination with venetoclax constitutes a new metabolism-targeted approach to overcome resistance to Bcl-2 inhibition and standard of care treatment in AML

Katie H. Hurrish, Yongwei Su, Shraddha Patel, Sandra E. Wiley, Zhanjun Hou, Jenna Carter, Hasini Kalpage, Maik Hüttemann, Connie Weng, Holly Edwards, Lisa Polin, Jing Li, Jay Yang, Larry H. Matherly, Sergej Naumovich Konoplev, Jeffrey W. Taub, Marina Konopleva, Yubin Ge, Natalia Baran
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3785.
https://doi.org/10.1158/1538-7445.AM2022-3785
Published: 15 June 2022
View article titled, Abstract 3785: ME-344, a novel isoflavone mitochondrial inhibitor, in combination with venetoclax constitutes a new metabolism-targeted approach to overcome resistance to Bcl-2 inhibition and standard of care treatment in AML
Journal Articles

Abstract 5337: Tolinapant (ASTX660) enhances the anti-leukemic activity of Venetoclax and Dexamethasone in T cell acute lymphoblastic leukemia (T-ALL)

Priyanka Sharma, Sujan Piya, Huaxian Ma, Natalia Baran, Muharrem Muftuoglu, Mahesh Basyal, Vivian Ruvolo, George Ward, Tomoko Smyth, Martin J. Sims, Michael Andreeff, Gautam Borthakur
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5337.
https://doi.org/10.1158/1538-7445.AM2022-5337
Published: 15 June 2022
View article titled, Abstract 5337: Tolinapant (ASTX660) enhances the anti-leukemic activity of Venetoclax and Dexamethasone in T cell acute lymphoblastic leukemia (T-ALL)
Journal Articles

Abstract 342: S63845, a novel BH3 mimetic Mcl-1 inhibitor synergizes with midostaurin to induce potent apoptosis in acute myeloid leukemia cells carrying FLT3-ITD mutations

Anna Skwarska, Qi Zhang, Shelley M. Herbrich, Natalia Baran, Ensar Halilovic, Peter Ruvolo, Vivian Ruvolo, Erick Morris, Andrew Wei, Donia Moujalled, Michael Andreff, Marina Konopleva
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 342.
https://doi.org/10.1158/1538-7445.AM2019-342
Published: 01 July 2019
View article titled, Abstract 342: S63845, a novel BH3 mimetic Mcl-1 inhibitor synergizes with midostaurin to induce potent apoptosis in acute myeloid leukemia cells carrying FLT3-ITD mutations
Journal Articles

Abstract 1875: Oxidative metabolism as a novel therapeutic target to eradicate T-ALL with mitochondrial complex I inhibitor IACS-010759

Natalia Baran, Alessia Lodi, Shannon Sweeney, Vinitha Mary Kuruvilla, Antonio Cavazos, Anna Skwarska, Sriram Shanmuga Velandy, Karine Harutyunyan, Ningping Feng, Jason Gay, Marcin Kaminski, Elias J. Jabbour, Adolfo Ferrando, M. Emilia Di Francesco, Joseph R. Marszalek, Stefano Tiziani, Marina Konopleva
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1875.
https://doi.org/10.1158/1538-7445.AM2018-1875
Published: 01 July 2018
View article titled, Abstract 1875: Oxidative metabolism as a novel therapeutic target to eradicate T-ALL with mitochondrial complex I inhibitor IACS-010759
Journal Articles

Cell Division Patterns in Acute Myeloid Leukemia Stem-like Cells Determine Clinical Course: A Model to Predict Patient Survival

Thomas Stiehl, Natalia Baran, Anthony D. Ho, Anna Marciniak-Czochra
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (6): 940–949.
https://doi.org/10.1158/0008-5472.CAN-14-2508
Published: 12 March 2015
View article titled, Cell Division Patterns in Acute Myeloid Leukemia Stem-like Cells Determine Clinical Course: A Model to Predict Patient Survival
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Includes: Supplementary data