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Nasser K. Altorki
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Journal Articles

Abstract 5489: The spatial landscape of early-stage lung adenocarcinoma

Junbum Kim, Hiranmayi Ravichandran, Liron Yoffe, Bhavneet Binder, Timothy McGraw, Nasser K. Altorki, Vivek Mittel, Olivier Elemento
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5489.
https://doi.org/10.1158/1538-7445.AM2024-5489
Published: 22 March 2024
View article titled, Abstract 5489: The spatial landscape of early-stage lung adenocarcinoma
Journal Articles

Abstract 4097: LNP-mRNA neoantigen vaccines to intercept progression of pre-invasive to invasive lung adenocarcinoma

Yongfeng He, Sijin Luo Zhong, Bhavneet Bhinder, Geoffrey Markowitz, Arshdeep Singh, Eric Gardner, Myung Soo Ko, Nasser K. Altorki, Shaoyi Jiang, Vivek Mittal
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4097.
https://doi.org/10.1158/1538-7445.AM2024-4097
Published: 22 March 2024
View article titled, Abstract 4097: LNP-mRNA neoantigen vaccines to intercept progression of pre-invasive to invasive lung adenocarcinoma
Journal Articles

Abstract 2: T cells selected from lymph node acquisition for adoptive cell therapyin NSCLC

Tatiana Delgado Cruz, Yanping Yang, Rachel Honigsberg, Geoffrey Markowitz, Nasser K Altorki, Vivek Mittal, Moonsoo M. Jin, Jonathan Villena-Vargas
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2.
https://doi.org/10.1158/1538-7445.AM2024-2
Published: 22 March 2024
View article titled, Abstract 2: T cells selected from lymph node acquisition for adoptive cell therapyin NSCLC
Journal Articles

Abstract 603: Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway to generate TCF1+ progenitor CD8+ T cells to improve checkpoint blockade

Geoffrey J. Markowitz, Yi Ban, Diamile A. Tavarez, Michael J. Crowley, Liron Yoffe, Mitchell T. Martin, Tito A. Sandoval, Dingcheng Gao, Juan R. Cubillos-Ruiz, Timothy E. McGraw, Nasser K. Altorki, Vivek Mittal
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 603.
https://doi.org/10.1158/1538-7445.AM2023-603
Published: 04 April 2023
View article titled, Abstract 603: Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway to generate TCF1+ progenitor CD8+ T cells to improve checkpoint blockade
Journal Articles

Abstract 5709: Whole genome error-corrected sequencing for sensitive circulating tumor DNA cancer monitoring

Alexandre P. Cheng, Adam J. Widman, Anushri Arora, Itai Rusinek, William F. Hooper, Rebecca Murray, Daniel Halmos, Theophile Langanay, Giorgio Inghirami, Soren Germer, Melissa Marton, Adrienne Helland, Rob Furatero, Jaime McClintock, Lara Winterkorn, Zoe Steinsnyder, Yohyoh Wang, Srinivas Rajagopalan, Asrar I. Alimohamed, Murtaza S. Malbari, Ashish Saxena, Margaret K. Callahan, Dennie T. Frederick, Lavinia Spain, Ariel Jaimovich, Doron Lipson, Samra Turajlic, Michael C. Zody, Nasser K. Altorki, Jedd D. Wolchok, Michael A. Postow, Nicolas Robine, Genevieve Boland, Dan A. Landau
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5709.
https://doi.org/10.1158/1538-7445.AM2023-5709
Published: 04 April 2023
View article titled, Abstract 5709: Whole genome error-corrected sequencing for sensitive circulating tumor DNA cancer monitoring
Journal Articles

Abstract 5884: Targeting T regulatory cells to intercept progression from preinvasive to invasive lung adenocarcinoma using a novel KRAS-driven murine model

Mitchell Martin, Michael J. Crowley, Geoffrey Markowitz, Alain Borczuk, Chen Zhang, Liron Yoffe, Arshdeep Singh, Nasser K. Altorki, Vivek Mittal
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5884.
https://doi.org/10.1158/1538-7445.AM2023-5884
Published: 04 April 2023
View article titled, Abstract 5884: Targeting T regulatory cells to intercept progression from preinvasive to invasive lung adenocarcinoma using a novel KRAS-driven murine model
Journal Articles

Abstract 68: Dissecting cellular and molecular alterations in pre-invasive to invasive lung cancer progression at single-cell resolution

Liron Yoffe, Alain Borczuk, Timothy E. McGraw, Olivier Elemento, Nasser K. Altorki, Vivek Mittal
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 68.
https://doi.org/10.1158/1538-7445.AM2023-68
Published: 04 April 2023
View article titled, Abstract 68: Dissecting cellular and molecular alterations in pre-invasive to invasive lung cancer progression at single-cell resolution
Journal Articles

Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis

Ana Rita Lourenco, Yi Ban, Michael J. Crowley, Sharrell B. Lee, Divya Ramchandani, Wei Du, Olivier Elemento, Jason T. George, Mohit Kumar Jolly, Herbert Levine, Jianting Sheng, Stephen T. Wong, Nasser K. Altorki, Dingcheng Gao
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (2): 163–169.
https://doi.org/10.1158/0008-5472.CAN-19-1427
Published: 15 January 2020
View article titled, Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis
Open the PDF for Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 4498: Targeting IRE1a-XBP1 signaling in lung cancer

Michael J. Crowley, Shira Yomtoubian, Geoffrey Markowitz, Nasser K. Altorki, Dingcheng Gao, Juan Cubillos-Ruiz, Vivek Mittal
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4498.
https://doi.org/10.1158/1538-7445.AM2017-4498
Published: 01 July 2017
View article titled, Abstract 4498: Targeting IRE1a-XBP1 signaling in lung cancer
Journal Articles

Abstract 2637: Impact of pre-diagnosis weight loss on outcomes in a prospective cohort of esophageal cancer patients

Sherry Shen, James L. Araujo, Nasser K. Altorki, Joshua R. Sonett, Adriana Rodriguez, Kivilcim Sungur-Stasik, Alfred I. Neugut, Julian A. Abrams
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2637.
https://doi.org/10.1158/1538-7445.AM2016-2637
Published: 15 July 2016
View article titled, Abstract 2637: Impact of pre-diagnosis weight loss on outcomes in a prospective cohort of esophageal cancer patients
Journal Articles

Abstract 4721: Epithelial to mesenchymal transition is not required for breast to lung metastasis but contributes to chemoresistance

Kari R. Fischer, Anna Durrans, Sharrell Lee, Jianting Sheng, Hyejin Choi, Fuhai Li, Stephen Wong, Nasser K. Altorki, Vivek Mittal, Dingcheng Gao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4721.
https://doi.org/10.1158/1538-7445.AM2015-4721
Published: 01 August 2015
View article titled, Abstract 4721: Epithelial to mesenchymal transition is not required for breast to lung metastasis but contributes to chemoresistance
Journal Articles

Abstract 1159: A novel HGF-MET paracrine signaling pathway promotes growth and resistance to chemotherapy in lung cancer

Hyejin Choi, Ding Cheng Gao, Sharrell B. Lee, Anna Durrans, Seongho Ryu, Olivier Elemento, Stephen Wong, Nasser K. Altorki, Vivek Mittal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1159.
https://doi.org/10.1158/1538-7445.AM2014-1159
Published: 01 October 2014
View article titled, Abstract 1159: A novel HGF-MET paracrine signaling pathway promotes growth and resistance to chemotherapy in lung cancer
Journal Articles

Abstract 4972: Analysis of the reprogrammed bone marrow-derived stroma in lung cancer unravels potential targets for prognosis and therapy.

Anna Durrans, Dingcheng Gao, Ravi Gupta, Seongho Ryu, Navneet Narula, Kari R. Fischer, Hyejin Choi, Brendon M. Stiles, Abu Nasar, Ramana V. Davuluri, Nasser K. Altorki, Vivek Mittal
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4972.
https://doi.org/10.1158/1538-7445.AM2013-4972
Published: 15 April 2013
View article titled, Abstract 4972: Analysis of the reprogrammed bone marrow-derived stroma in lung cancer unravels potential targets for prognosis and therapy.
Journal Articles

Myeloid Progenitor Cells in the Premetastatic Lung Promote Metastases by Inducing Mesenchymal to Epithelial Transition

Dingcheng Gao, Natasha Joshi, Hyejin Choi, Seongho Ryu, Mary Hahn, Raul Catena, Helen Sadik, Pedram Argani, Patrick Wagner, Linda T. Vahdat, Jeffrey L. Port, Brendon Stiles, Saraswati Sukumar, Nasser K. Altorki, Shahin Rafii, Vivek Mittal
Journal: Cancer Research
Cancer Res (2012) 72 (6): 1384–1394.
https://doi.org/10.1158/0008-5472.CAN-11-2905
Published: 14 March 2012
View article titled, Myeloid Progenitor Cells in the Premetastatic Lung Promote Metastases by Inducing Mesenchymal to Epithelial Transition
Open the PDF for Myeloid Progenitor Cells in the Premetastatic Lung Promote Metastases by Inducing Mesenchymal to Epithelial Transition in another window
Includes: Supplementary data
Journal Articles

Tobacco Smoke Stimulates the Transcription of Amphiregulin in Human Oral Epithelial Cells: Evidence of a Cyclic AMP-Responsive Element Binding Protein–Dependent Mechanism

Baoheng Du, Nasser K. Altorki, Levy Kopelovich, Kotha Subbaramaiah, Andrew J. Dannenberg
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5982–5988.
https://doi.org/10.1158/0008-5472.CAN-05-0628
Published: 01 July 2005
View article titled, Tobacco Smoke Stimulates the Transcription of Amphiregulin in Human Oral Epithelial Cells: Evidence of a Cyclic AMP-Responsive Element Binding Protein–Dependent Mechanism
Open the PDF for Tobacco Smoke Stimulates the Transcription of Amphiregulin in Human Oral Epithelial Cells: Evidence of a Cyclic AMP-Responsive Element Binding Protein–Dependent Mechanism in another window
Journal Articles

Levels of Cyclooxygenase-2 Are Increased in the Oral Mucosa of Smokers: Evidence for the Role of Epidermal Growth Factor Receptor and Its Ligands

Dimitrios Moraitis, Baoheng Du, Mariana S. De Lorenzo, Jay O. Boyle, Babette B. Weksler, Erik G. Cohen, John F. Carew, Nasser K. Altorki, Levy Kopelovich, Kotha Subbaramaiah, Andrew J. Dannenberg
Journal: Cancer Research
Cancer Res (2005) 65 (2): 664–670.
https://doi.org/10.1158/0008-5472.664.65.2
Published: 03 February 2005
View article titled, Levels of Cyclooxygenase-2 Are Increased in the Oral Mucosa of Smokers: Evidence for the Role of Epidermal Growth Factor Receptor and Its Ligands
Open the PDF for Levels of Cyclooxygenase-2 Are Increased in the Oral Mucosa of Smokers: Evidence for the Role of Epidermal Growth Factor Receptor and Its Ligands in another window
Journal Articles

Vaccine-induced CD4+ T cell responses to MAGE-3 protein in lung cancer patients

Djordje Atanackovic, Nasser K. Altorki, Elisabeth Stockert, Barbara Williamson, Achim A. Jungbluth, Erika Ritter, Darren Santiago, Cathy A. Ferrara, Mitsutoshi Matsuo, Annamalai Selvakumar, Bo Dupont, Yao-Tseng Chen, Eric W. Hoffman, Gerd Ritter, Lloyd J. Old, Sacha Gnjatic
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 325–326.
Published: 01 April 2004
View article titled, Vaccine-induced CD4<sup>+</sup> T cell responses to MAGE-3 protein in lung cancer patients
Journal Articles

Human Lung Cancer Antigens Recognized by Autologous Antibodies: Definition of a Novel cDNA Derived from the Tumor Suppressor Gene Locus on Chromosome 3p21.3

Ali O. Güre, Nasser K. Altorki, Elisabeth Stockert, Matthew J. Scanlan, Lloyd J. Old, Yao-Tseng Chen
Journal: Cancer Research
Cancer Res (1998) 58 (5): 1034–1041.
Published: 01 March 1998
View article titled, Human Lung Cancer Antigens Recognized by Autologous Antibodies: Definition of a Novel cDNA Derived from the Tumor Suppressor Gene Locus on Chromosome 3p21.3
Open the PDF for Human Lung Cancer Antigens Recognized by Autologous Antibodies: Definition of a Novel cDNA Derived from the Tumor Suppressor Gene Locus on Chromosome 3p21.3 in another window