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Abstract 3256: A novel therapy for mucinous adenocarcinoma of the ovary by using NVP-BEZ235 to inhibit PI3K and mTOR.

Akiko Kudoh, Tetsuro Oishi, Hiroaki Itamochi, Michiko Nonaka, Seiya Sato, Jun Naniwa, Shinya Sato, Muneaki Shimada, Naoki Terakawa, Junzo Kigawa, Tasuku Harada

Cancer Res (2013) 73 (8_Supplement): 3256.

DOI: https://doi.org/10.1158/1538-7445.AM2013-3256

Published: 15 April 2013

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Abstract 3740: NVP-BEZ235, a dual PI3K/ mTOR inhibitor, suppress tumorigenicity of ovarian clear cell carcinoma cells.

Tetsuro Oishi, Hiroaki Itamochi, Akiko Kudoh, Michiko Nonaka, Seiya Sato, Jun Naniwa, Shinya Sato, Muneaki Shimada, Naoki Terakawa, Junzo Kigawa, Tasuku Harada

Cancer Res (2012) 72 (8_Supplement): 3740.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3740

Published: 15 April 2012

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Journal Articles

Abstract 2561: Inhibiting the mTOR pathway synergistically enhances etoposide-induced cytotoxicity by upregulating c-Jun in ovarian cancer cells

Hiroaki Itamochi, Michiko Nonaka, Seiya Sato, Kazunori Uegaki, Jun Naniwa, Shinya Sato, Muneaki Shimada, Oishi Tetsuro, Naoki Terakawa, Junzo Kigawa, Tasuku Harada

Cancer Res (2011) 71 (8_Supplement): 2561.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2561

Published: 15 April 2011

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Journal Articles

Abstract 4497: NVP-BEZ235, a dual PI3K/ mTOR inhibitor, may be effective for ovarian clear cell carcinoma cells

Tetsuro Oishi, Hiroaki Itamochi, Michiko Nonaka, Seiya Sato, Jun Naniwa, Kazunori Uegaki, Shinya Sato, Muneaki Shimada, Naoki Terakawa, Junzo Kigawa, Tasuku Harada

Cancer Res (2011) 71 (8_Supplement): 4497.

DOI: https://doi.org/10.1158/1538-7445.AM2011-4497

Published: 15 April 2011

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Journal Articles

Abstract 3543: Activation of the ERK pathways overcome the cisplatin-resistance in ovarian carcinoma cells

Michiko Nonaka, Hiroaki Itamochi, Wakae Kawaguchi, Kazunori Uegaki, Jun Naniwa, Shinya Sato, Muneaki Shimada, Tetsuro Oishi, Naoki Terakawa, Junzo Kigawa, Tasuku Harada

Cancer Res (2010) 70 (8_Supplement): 3543.

DOI: https://doi.org/10.1158/1538-7445.AM10-3543

Published: 15 April 2010

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Journal Articles

Abstract #4580: Combination chemotherapy of oxaliplatin and 5-fluorouracil may be an effective regimen for mucinous adenocarcinoma of the ovary: A potential treatment strategy

Seiya Sato, Hiroaki Itamochi, Michiko Nonaka, Kazunori Uegaki, Jun Naniwa, Shinya Sato, Muneaki Shimada, Tetsuro Oishi, Junzo kigawa, Naoki Terakawa

Cancer Res (2009) 69 (9_Supplement): 4580.

Published: 01 May 2009

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Journal Articles

Galectin-3 may contribute to CDDP resistance in clear cell carcinoma of the ovary

Tetsuro Oishi, Hiroaki Itamochi, Seiya Sato, Wakae Kawaguchi, Ruri K. Shimogai, Shinya Sato, Masakuni Takahashi, Yasunobu Kanamori, Junzo Kigawa, Naoki Terakawa

Cancer Res (2006) 66 (8_Supplement): 304.

Published: 15 April 2006

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Adenovirus type 5 E1A gene therapy for ovarian clear cell carcinoma.

Hiroaki Itamochi, Junzo Kigawa, Yasunobu Kanamori, Tetsuro Oishi, Chandra Bartholomeusz, Rita Nahta, Francisco J. Esteva, Nour Sneige, Naoki Terakawa, Naoto T. Ueno

Cancer Res (2006) 66 (8_Supplement): 1289–1290.

Published: 15 April 2006

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Journal Articles

Bcl-2 Antisense Oligonucleotide Overcomes Resistance to E1A Gene Therapy in a Low HER2-Expressing Ovarian Cancer Xenograft Model

Chandra Bartholomeusz, Hiroaki Itamochi, Linda X.H. Yuan, Francisco J. Esteva, Christopher G. Wood, Naoki Terakawa, Mien-Chie Hung, Naoto T. Ueno

Cancer Res (2005) 65 (18): 8406–8413.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-1754

Published: 15 September 2005

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Journal Articles

Genetic diagnosis for chemosensitivity with drug-resistance genes in epithelial ovarian cancer

Jun Naniwa, Wakae Kawaguchi, Ruri Kaneko, Kazunori Uegaki, Muneaki Shimada, Masakuni Takahashi, Hiroaki Itamochi, Yasunobu Kanamori, Junzo Kigawa, Naoki Terakawa

Cancer Res (2005) 65 (9_Supplement): 1399–1400.

Published: 01 May 2005

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Journal Articles

Novel mechanism reduces proliferation of clear cell carcinoma of the ovary: cyclin-dependent kinase 2 (CDK2) activity is reduced by cytoplasmic sequestration of CDK2 by phosphorylated p27

Hiroaki Itamochi, Tomokazu Yoshida, Daisuke Aoki, Hideki Ishihara, Junzo Kigawa, Nao Suzuki, Shiro Nozawa, Naoki Terakawa, Naoto T. Ueno

Cancer Res (2005) 65 (9_Supplement): 1283.

Published: 01 May 2005

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Journal Articles

Cell-growth regulatory function of PTEN and prognosis in endometrial carcinoma

Kazunori Uegaki, Takahiro Iba, Hiroaki Itamochi, Yasunobu Kanamori, Junzo Kigawa, Jun Naniwa, Tetsuro Oishi, Muneaki Shimada, Naoki Terakawa

Cancer Res (2004) 64 (7_Supplement): 1028.

Published: 01 April 2004

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Journal Articles

Reduction of radiation-induced lung toxicities by specific expression of Bcl-2 in normal cells.

Hiroaki Itamochi, Tamotsu Sudo, Takeshi Takahashi, Chandra Bartholomeusz, Shalini Das, Naoki Terakawa, Elizabeth L. Travis, Naoto T. Ueno

Cancer Res (2004) 64 (7_Supplement): 872.

Published: 01 April 2004

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Journal Articles

Correlation between Expression of the Matrix Metalloproteinase-1 Gene in Ovarian Cancers and an Insertion/Deletion Polymorphism in Its Promoter Region

Yasunobu Kanamori, Mieko Matsushima, Takeo Minaguchi, Kanji Kobayashi, Satoru Sagae, Ryuichi Kudo, Naoki Terakawa, Yusuke Nakamura

Cancer Res (1999) 59 (17): 4225–4227.

Published: 01 September 1999

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Journal Articles

K-ras Activation in Neoplasms of the Human Female Reproductive Tract

Takayuki Enomoto, Masaki Inoue, Alan O. Perantoni, Naoki Terakawa, Osamu Tanizawa, Jerry M. Rice

Cancer Res (1990) 50 (19): 6139–6145.

Published: 01 October 1990

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Journal Articles

Growth Inhibition by Progestins in a Human Endometrial Cancer Cell Line with Estrogen-independent Progesterone Receptors

Naoki Terakawa, Miyoko Hayashida, Ikuya Shimizu, Hiromasa Ikegami, Hiroshi Wakimoto, Toshihiro Aono, Osamu Tanizawa, Keishi Matsumoto, Masato Nishida

Cancer Res (1987) 47 (7): 1918–1923.

Published: 01 April 1987

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NARROW

Abstract 3256: A novel therapy for mucinous adenocarcinoma of the ovary by using NVP-BEZ235 to inhibit PI3K and mTOR.

Abstract 3740: NVP-BEZ235, a dual PI3K/ mTOR inhibitor, suppress tumorigenicity of ovarian clear cell carcinoma cells.

Abstract 2561: Inhibiting the mTOR pathway synergistically enhances etoposide-induced cytotoxicity by upregulating c-Jun in ovarian cancer cells

Abstract 4497: NVP-BEZ235, a dual PI3K/ mTOR inhibitor, may be effective for ovarian clear cell carcinoma cells

Abstract 3543: Activation of the ERK pathways overcome the cisplatin-resistance in ovarian carcinoma cells

Abstract #4580: Combination chemotherapy of oxaliplatin and 5-fluorouracil may be an effective regimen for mucinous adenocarcinoma of the ovary: A potential treatment strategy

Galectin-3 may contribute to CDDP resistance in clear cell carcinoma of the ovary

Adenovirus type 5 E1A gene therapy for ovarian clear cell carcinoma.

Bcl-2 Antisense Oligonucleotide Overcomes Resistance to E1A Gene Therapy in a Low HER2-Expressing Ovarian Cancer Xenograft Model

Genetic diagnosis for chemosensitivity with drug-resistance genes in epithelial ovarian cancer

Novel mechanism reduces proliferation of clear cell carcinoma of the ovary: cyclin-dependent kinase 2 (CDK2) activity is reduced by cytoplasmic sequestration of CDK2 by phosphorylated p27

Cell-growth regulatory function of PTEN and prognosis in endometrial carcinoma

Reduction of radiation-induced lung toxicities by specific expression of Bcl-2 in normal cells.

Correlation between Expression of the Matrix Metalloproteinase-1 Gene in Ovarian Cancers and an Insertion/Deletion Polymorphism in Its Promoter Region

K-ras Activation in Neoplasms of the Human Female Reproductive Tract

Growth Inhibition by Progestins in a Human Endometrial Cancer Cell Line with Estrogen-independent Progesterone Receptors

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