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Journal Articles

Abstract 6590: Novel WRN helicase inhibitors selectively target microsatellite unstable cancer cells

Gabriele Picco, Yanhua Rao, Angham Al Saedi, Sara F. Vieira, Yang Lee, Ray Shenje, Shriram Bhosle, Samantha Walker, Kieron May, Carmen Herranz-Ors, Cansu Dicer, Freddy Gibson, Ruby Banerjee, Thilo Werner, Josh Cottom, Yang Peng, Nanhua Deng, Phil Landis, Thomas Angel, Jacob Bush, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Howard Lightfoot, Francesca Zappacosta, Jonathan Pettinger, Syd Barthorpe, Chris Eberl, Brian Jones, Jess Schneck, Dennis Murphy, Josh Taygerly, Mike DeMartino, Matthew Coelho, Jon Houseley, Benjamin Schwartz, Mathew J. Garnett
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6590.
https://doi.org/10.1158/1538-7445.AM2024-6590
Published: 22 March 2024
View article titled, Abstract 6590: Novel WRN helicase inhibitors selectively target microsatellite unstable cancer cells
Journal Articles

Abstract 3215: STAT3 antisense oligonucleotide (ASO) reverses immunosuppression and enhances cytotoxic cell function to enhance PDL1 blockade

Srimathi Srinivasan, Yang Xu, Theresa Proia, Nanhua Deng, J. Carl Barrett, Alexandra-Chloe Villani, Patricia E. McCoon
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3215.
https://doi.org/10.1158/1538-7445.AM2019-3215
Published: 01 July 2019
View article titled, Abstract 3215: STAT3 antisense oligonucleotide (ASO) reverses immunosuppression and enhances cytotoxic cell function to enhance PDL1 blockade
Journal Articles

Abstract 3751: Inhibition of A2AR by AZD4635 induces anti-tumor immunity alone and in combination with anti-PD-L1 in preclinical models

Alexandra Borodovsky, Yanjun Wang, Minwei Ye, Joseph C. Shaw, Kris Sachsenmeier, Nanhua Deng, Kelly Goodwin, James D. Clarke, Richard Goodwin, Nicole Strittmatter, Carl Hay, Vasu Sah, Lawson Deborah, Corinne Reimer, Miles Congreve, Jonathan Mason, Fiona Marshall, Paul Lyne, Richard Woessner
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3751.
https://doi.org/10.1158/1538-7445.AM2018-3751
Published: 01 July 2018
View article titled, Abstract 3751: Inhibition of A<sub>2A</sub>R by AZD4635 induces anti-tumor immunity alone and in combination with anti-PD-L1 in preclinical models
Journal Articles

Abstract 3684: Inhibition of STAT3 by antisense oligonucleotide treatment decreases the immune suppressive tumor microenvironment in syngeneic and GEM tumor models

Rich Woessner, Vasu Sah, Patricia McCoon, Shaun Grosskurth, Nanhua Deng, Rachel DuPont, Deborah Lawson, Lourdes Pablo, Corinne Reimer, Marco A. De Velasco, Hirotsugu Uemura, Juliana Candido, Paul Lyne
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3684.
https://doi.org/10.1158/1538-7445.AM2017-3684
Published: 01 July 2017
View article titled, Abstract 3684: Inhibition of STAT3 by antisense oligonucleotide treatment decreases the immune suppressive tumor microenvironment in syngeneic and GEM tumor models
Journal Articles

Abstract 5580: Preclinical pharmacodynamics and antitumor activity of AZD4635, a novel adenosine 2A receptor inhibitor that reverses adenosine mediated T cell suppression

Alexandra Borodovsky, Yanjun Wang, Minwei Ye, Joseph C. Shaw, Kris F. Sachsenmeier, Nanhua Deng, Kelly J. DelSignore, Adrian J. Fretland, James D. Clarke, Richard J. Goodwin, Nicole Strittmatter, Carl Hay, Vasu R. Sah, Deborah Lawson, Corinne Reimer, Miles Congreve, Jonathan S. Mason, Fiona H. Marshall, Paul Lyne, Richard Woessner
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5580.
https://doi.org/10.1158/1538-7445.AM2017-5580
Published: 01 July 2017
View article titled, Abstract 5580: Preclinical pharmacodynamics and antitumor activity of AZD4635, a novel adenosine 2A receptor inhibitor that reverses adenosine mediated T cell suppression
Journal Articles

Abstract 4046: Targeting jak/stat adaptive mechanism with jak1 inhibitor azd4205 reduces residual disease and prolongs benefit of osimertinib

Huawei (Ray) Chen, Geraldine Bebernitz, Kirsten Bell, Erica Anderson, Nanhua Deng, Jason Kettle, Paul Lyne, Richard Woessner
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4046.
https://doi.org/10.1158/1538-7445.AM2017-4046
Published: 01 July 2017
View article titled, Abstract 4046: Targeting jak/stat adaptive mechanism with jak1 inhibitor azd4205 reduces residual disease and prolongs benefit of osimertinib
Journal Articles

Abstract 3267: Human population based engineered breast tumor model for in vivo biomarker discovery

Min Wu, Kimberly Clark, Nanhua Deng, Zuhua Cai, Megan E. Serpa, Tong Zi, Xiaojian Sun, Richard Nicoletti, Kathryn Sun, Bing Feng, Jie Lin, Joerg Heyer, M Isabel Chiu, Murray O. Robinson
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3267.
https://doi.org/10.1158/1538-7445.AM10-3267
Published: 15 April 2010
View article titled, Abstract 3267: Human population based engineered breast tumor model for in vivo biomarker discovery
Journal Articles

Macrophage Colony-stimulating Factor (CSF-1) Enhances Invasiveness in CSF-1 Receptor-positive Carcinoma Cell Lines

Andrew E. Filderman, Andrew Bruckner, Barry M. Kacinski, Nanhua Deng, Heinz G. Remold
Journal: Cancer Research
Cancer Res (1992) 52 (13): 3661–3666.
Published: 01 July 1992
View article titled, Macrophage Colony-stimulating Factor (CSF-1) Enhances Invasiveness in CSF-1 Receptor-positive Carcinoma Cell Lines
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