1-20 of 20
Nancy E. Hynes
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 3685: Sustained Ret expression during mammary gland post-lactation induces premature involution and enhances cancer potential

Sabrina A. Vallone, Martín García Solá, Robert D. Cardiff, Roberto P. Meiss, Lewis A. Chodosh, Carolina Shere-Levy, Edith C C. Kordon, Nancy E. Hynes, Albana Gattelli
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3685.
https://doi.org/10.1158/1538-7445.AM2020-3685
Published: 15 August 2020
View article titled, Abstract 3685: Sustained Ret expression during mammary gland post-lactation induces premature involution and enhances cancer potential
Journal Articles

ErbB2: From an EGFR Relative to a Central Target for Cancer Therapy

Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2016) 76 (13): 3659–3662.
https://doi.org/10.1158/0008-5472.CAN-16-1356
Published: 30 June 2016
View article titled, ErbB2: From an EGFR Relative to a Central Target for Cancer Therapy
Open the PDF for ErbB2: From an EGFR Relative to a Central Target for Cancer Therapy in another window
Journal Articles

Abstract LB-013: The immunomodulatory effect of JAK inhibitors enhances metastasis by impairing antitumor immunity in preclinical models of breast cancer

Nancy E. Hynes, Alessia Bottos, Jason Gill, Thomas Radimerski, Alexander Tzankov, Aleksandra Wodnar-Filipowicz
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-013.
https://doi.org/10.1158/1538-7445.AM2015-LB-013
Published: 01 August 2015
View article titled, Abstract LB-013: The immunomodulatory effect of JAK inhibitors enhances metastasis by impairing antitumor immunity in preclinical models of breast cancer
Journal Articles

Abstract P1-07-19: Effects of JAK pathway inhibition in pre-clinical models of breast cancer bone marrow metastases

Alessia Bottos, Jason Gill, Thomas Radimerski, Alexandar Tzankov, Aleksandra Wodnar-Filipowicz, Nancy E Hynes
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P1-07-19.
https://doi.org/10.1158/1538-7445.SABCS14-P1-07-19
Published: 01 May 2015
View article titled, Abstract P1-07-19: Effects of JAK pathway inhibition in pre-clinical models of breast cancer bone marrow metastases
Journal Articles

Abstract SY20-02: Insights into mechanisms of breast cancer metastasis

Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): SY20-02.
https://doi.org/10.1158/1538-7445.AM2014-SY20-02
Published: 01 October 2014
View article titled, Abstract SY20-02: Insights into mechanisms of breast cancer metastasis
Journal Articles

Abstract 1479: Targeting breast cancer bone metastases looking at the cross-talk between tumor cells and bone environment

Alessia Bottos, Jason Gill, Aleksandra Wodnar-Filipowicz, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1479.
https://doi.org/10.1158/1538-7445.AM2012-1479
Published: 15 April 2012
View article titled, Abstract 1479: Targeting breast cancer bone metastases looking at the cross-talk between tumor cells and bone environment
Journal Articles

Potential for Targeting the Fibroblast Growth Factor Receptors in Breast Cancer

Nancy E. Hynes, Julien H. Dey
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5199–5202.
https://doi.org/10.1158/0008-5472.CAN-10-0918
Published: 30 June 2010
View article titled, Potential for Targeting the Fibroblast Growth Factor Receptors in Breast Cancer
Open the PDF for Potential for Targeting the Fibroblast Growth Factor Receptors in Breast Cancer in another window
Journal Articles

Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis

Julien H. Dey, Fabrizio Bianchi, Johannes Voshol, Debora Bonenfant, Edward J. Oakeley, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2010) 70 (10): 4151–4162.
https://doi.org/10.1158/0008-5472.CAN-09-4479
Published: 12 May 2010
View article titled, Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Open the PDF for Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 3380: The serine protease inhibitor PN-1 induces activation of FGFR-mediated signaling

Berengere Fayard, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3380.
https://doi.org/10.1158/1538-7445.AM10-3380
Published: 15 April 2010
View article titled, Abstract 3380: The serine protease inhibitor PN-1 induces activation of FGFR-mediated signaling
Journal Articles

The Serine Protease Inhibitor Protease Nexin-1 Controls Mammary Cancer Metastasis through LRP-1–Mediated MMP-9 Expression

Bérengère Fayard, Fabrizio Bianchi, Julien Dey, Eliza Moreno, Sabrina Djaffer, Nancy E. Hynes, Denis Monard
Journal: Cancer Research
Cancer Res (2009) 69 (14): 5690–5698.
https://doi.org/10.1158/0008-5472.CAN-08-4573
Published: 15 July 2009
View article titled, The Serine Protease Inhibitor Protease Nexin-1 Controls Mammary Cancer Metastasis through LRP-1–Mediated MMP-9 Expression
Open the PDF for The Serine Protease Inhibitor Protease Nexin-1 Controls Mammary Cancer Metastasis through LRP-1–Mediated MMP-9 Expression in another window
Includes: Supplementary data
Journal Articles

The Ret Receptor Tyrosine Kinase Pathway Functionally Interacts with the ERα Pathway in Breast Cancer

Anne Boulay, Madlaina Breuleux, Christine Stephan, Caroline Fux, Cathrin Brisken, Maryse Fiche, Markus Wartmann, Michael Stumm, Heidi A. Lane, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3743–3751.
https://doi.org/10.1158/0008-5472.CAN-07-5100
Published: 15 May 2008
View article titled, The Ret Receptor Tyrosine Kinase Pathway Functionally Interacts with the ERα Pathway in Breast Cancer
Open the PDF for The Ret Receptor Tyrosine Kinase Pathway Functionally Interacts with the ERα Pathway in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics

Patrizia Sini, Ivana Samarzija, Fabienne Baffert, Amanda Littlewood-Evans, Christian Schnell, Andreas Theuer, Sven Christian, Anja Boos, Holger Hess-Stumpp, John A. Foekens, Buddy Setyono-Han, Jeanette Wood, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2008) 68 (5): 1581–1592.
https://doi.org/10.1158/0008-5472.CAN-06-4685
Published: 03 March 2008
View article titled, Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics
Open the PDF for Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics in another window
Includes: Supplementary data
Journal Articles

Role of VEGFR signaling in tumor cells

Patrizia Sini, Fabienne Baffert, Jeanette Wood, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 659.
Published: 15 April 2006
View article titled, Role of VEGFR signaling in tumor cells
Journal Articles

The Efficacy of ErbB Receptor-targeted Anticancer Therapeutics Is Influenced by the Availability of Epidermal Growth Factor-related Peptides

Andrea B. Motoyama, Nancy E. Hynes, Heidi A. Lane
Journal: Cancer Research
Cancer Res (2002) 62 (11): 3151–3158.
Published: 01 June 2002
View article titled, The Efficacy of ErbB Receptor-targeted Anticancer Therapeutics Is Influenced by the Availability of Epidermal Growth Factor-related Peptides
Open the PDF for The Efficacy of ErbB Receptor-targeted Anticancer Therapeutics Is Influenced by the Availability of Epidermal Growth Factor-related Peptides in another window
Journal Articles

Interleukin 6 Inhibits Proliferation and, in Cooperation with an Epidermal Growth Factor Receptor Autocrine Loop, Increases Migration of T47D Breast Cancer Cells

Ali Badache, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2001) 61 (1): 383–391.
Published: 01 January 2001
View article titled, Interleukin 6 Inhibits Proliferation and, in Cooperation with an Epidermal Growth Factor Receptor Autocrine Loop, Increases Migration of T47D Breast Cancer Cells
Open the PDF for Interleukin 6 Inhibits Proliferation and, in Cooperation with an Epidermal Growth Factor Receptor Autocrine Loop, Increases Migration of T47D Breast Cancer Cells in another window
Journal Articles

Neu Differentiation Factor Induces ErbB2 Down-Regulation and Apoptosis of ErbB2-overexpressing Breast Tumor Cells

John M. Daly, Christian B. Jannot, Roger R. Beerli, Diana Graus-Porta, Francisca G. Maurer, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (1997) 57 (17): 3804–3811.
Published: 01 September 1997
View article titled, Neu Differentiation Factor Induces ErbB2 Down-Regulation and Apoptosis of ErbB2-overexpressing Breast Tumor Cells
Open the PDF for Neu Differentiation Factor Induces ErbB2 Down-Regulation and Apoptosis of ErbB2-overexpressing Breast Tumor Cells in another window
Journal Articles

Correspondence re: B. Fernandes et al., β1–6 Branched Oligosaccharides as a Marker of Tumor Progression in Human Breast and Colon Neoplasia. Cancer Res., 51: 718–723, 1991

Roger Chammas, Nathalie Cella, Lourdes A. Marques, Ricardo R. Brentani, Nancy E. Hynes, Eduardo L. F. Franco
Journal: Cancer Research
Cancer Res (1994) 54 (1): 306–307.
Published: 01 January 1994
View article titled, Correspondence re: B. Fernandes <em>et al.</em>, <em>β</em>1–6 Branched Oligosaccharides as a Marker of Tumor Progression in Human Breast and Colon Neoplasia. Cancer Res., <em>51:</em> 718–723, 1991
Open the PDF for Correspondence re: B. Fernandes <em>et al.</em>, <em>β</em>1–6 Branched Oligosaccharides as a Marker of Tumor Progression in Human Breast and Colon Neoplasia. Cancer Res., <em>51:</em> 718–723, 1991 in another window
Journal Articles

Selective Inhibition of Tumor Cell Growth by a Recombinant Single-Chain Antibody-Toxin Specific for the erbB-2 Receptor

Winfried Wels, Ina-Maria Harwerth, Marcel Mueller, Bernd Groner, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (1992) 52 (22): 6310–6317.
Published: 01 November 1992
View article titled, Selective Inhibition of Tumor Cell Growth by a Recombinant Single-Chain Antibody-Toxin Specific for the erbB-2 Receptor
Open the PDF for Selective Inhibition of Tumor Cell Growth by a Recombinant Single-Chain Antibody-Toxin Specific for the erbB-2 Receptor in another window
Journal Articles

γ-Interferon Reduces Expression of the Protooncogene c-erbB-2 in Human Ovarian Carcinoma Cells

Christian Marth, Elisabeth Müller-Holzner, Evi Greiter, Marcus V. Cronauer, Alain G. Zeimet, Wolfgang Doppler, Brigitte Eibl, Nancy E. Hynes, Günter Daxenbichler
Journal: Cancer Research
Cancer Res (1990) 50 (21): 7037–7041.
Published: 01 November 1990
View article titled, γ-Interferon Reduces Expression of the Protooncogene c-<em>erb</em>B-2 in Human Ovarian Carcinoma Cells
Open the PDF for γ-Interferon Reduces Expression of the Protooncogene c-<em>erb</em>B-2 in Human Ovarian Carcinoma Cells in another window
Journal Articles

Correlation of c-erbB-2 Gene Amplification and Protein Expression in Human Breast Carcinoma with Nodal Status and Nuclear Grading

Mark S. Berger, Gottfried W. Locher, Susanne Saurer, William J. Gullick, Michael D. Waterfield, Bernd Groner, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (1988) 48 (5): 1238–1243.
Published: 01 March 1988
View article titled, Correlation of c-<em>erbB</em>-2 Gene Amplification and Protein Expression in Human Breast Carcinoma with Nodal Status and Nuclear Grading
Open the PDF for Correlation of c-<em>erbB</em>-2 Gene Amplification and Protein Expression in Human Breast Carcinoma with Nodal Status and Nuclear Grading in another window