1-19 of 19
Nancy Dumont
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 73: A ubiquitination cascade regulating the integrated stress response and survival in carcinomas

Lisa D. Cervia, Tsukasa Shibue, Benjamin Gaeta, Ashir A. Borah, Lisa Leung, Naomi Li, Nancy Dumont, Alfredo Gonzalez, Nolan Bick, Mariya Kazachkova, Joshua M. Dempster, John M. Krill-Burger, Federica Piccioni, Namrata D. Udeshi, Meagan E. Olive, Steven A. Carr, David E. Root, James M. McFarland, Francisca Vazquez, William C. Hahn
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 73.
https://doi.org/10.1158/1538-7445.AM2022-73
Published: 15 June 2022
View article titled, Abstract 73: A ubiquitination cascade regulating the integrated stress response and survival in carcinomas
Journal Articles

Abstract 1028: Phosphate dysregulation as a novel therapeutic strategy in ovarian and uterine cancers

Daniel Bondeson, Brenton Paolella, Adhana Asfaw, Michael Rothberg, Thomas Skipper, Gabriel Mesa, Alfredo Gonzalez, Lauren E. Surface, Kentaro Ito, Mariya Kazachkova, William N. Colgan, Allie Warren, Joshua Dempster, J Michael Krill-Burger, Maria Ericsson, Andrew Tang, Iris Fung, Emily S. Chambers, Mai Abdusamad, Nancy Dumont, John Doench, Federica Piccioni, David Root, Jesse Boehm, William C. Hahn, Michael Mannstadt, James McFarland, Francisca Vazquez, Todd Golub
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1028.
https://doi.org/10.1158/1538-7445.AM2022-1028
Published: 15 June 2022
View article titled, Abstract 1028: Phosphate dysregulation as a novel therapeutic strategy in ovarian and uterine cancers
Journal Articles

Abstract P3-09-01: A ubiquitination cascade regulating the integrated stress response and survival in carcinomas

Lisa D Cervia, Tsukasa Shibue, Benjamin Gaeta, Ashir A Borah, Lisa Leung, Naomi Li, Nancy Dumont, Alfredo Gonzalez, Nolan Bick, Mariya Kazachkova, Joshua M Dempster, John M Krill-Burger, Federica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-09-01.
https://doi.org/10.1158/1538-7445.SABCS21-P3-09-01
Published: 15 February 2022
View article titled, Abstract P3-09-01: A ubiquitination cascade regulating the integrated stress response and survival in carcinomas
Journal Articles

Abstract NG01: Synthetic lethal interaction between the ESCRT paralog enzymes VPS4A and VPS4B in cancers harboring loss of chromosome 18q or 16q

Jasper E. Neggers, Brenton Paolella, Adhana Asfaw, Michael V. Rothberg, Tom A. Skipper, Radha Kalekar, Michael Burger, Neekesh Dharia, Guillaume Kugener, Jeremie Kalfon, Nancy Dumont, Yvonne Li, Liam Spurr, Annan Yang, Wenbo Wu, AndrewAdam Durbin, Brian M. Wolpin, David E. Root, Jesse Boehm, Andrew D. Cherniack, Aviad Tsherniak, Andrew L. Hong, William C. Hahn, Kimberly Stegmaier, Todd Golub, Francisca Vazquez, Andrew J. Aguirre
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): NG01.
https://doi.org/10.1158/1538-7445.AM2021-NG01
Published: 01 July 2021
View article titled, Abstract NG01: Synthetic lethal interaction between the ESCRT paralog enzymes VPS4A and VPS4B in cancers harboring loss of chromosome 18q or 16q
Journal Articles

Abstract 1950: A ubiquitination cascade regulates the integrated stress response and epithelial cancer survival

Lisa D. Cervia, Tsukasa Shibue, Benjamin Gaeta, Ashir Borah, Lisa Leung, Naomi Li, Nancy Dumont, Alfredo Gonzalez, Nolan Bick, Mariya Kazachkova, Joshua Dempster, John M. Krill-Burger, Namrata Udeshi, Meagan Olive, Steven A. Carr, David E. Root, Federica Piccioni, James M. McFarland, Francisca Vazquez, William C. Hahn
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1950.
https://doi.org/10.1158/1538-7445.AM2021-1950
Published: 01 July 2021
View article titled, Abstract 1950: A ubiquitination cascade regulates the integrated stress response and epithelial cancer survival
Journal Articles

Abstract PO-011: Synthetic lethal interaction between the ESCRT paralog enzymes VPS4A and VPS4B in SMAD4 or CDH1-deleted cancers

Jasper E. Neggers, Brenton R. Paolella, Adhana Asfaw, Michael V. Rothberg, Thomas A. Skipper, Radha L. Kalekar, Michael J. Krill-Burger, Neekesh V. Dharia, Guillaume Kugener, Adam D. Durbin, Annan Yang, Nancy Dumont, Yvonne Y. Li, Brian M. Wolpin, Federica Piccioni, David E. Root, Jesse S. Boehm, Andrew D. Cherniack, Aviad Tsherniak, Andrew L. Hong, William C. Hahn, Kimberly Stegmaier, Todd R. Golub, Francisca Vazquez, Andrew J. Aguirre
Journal: Cancer Research
Cancer Res (2020) 80 (22_Supplement): PO-011.
https://doi.org/10.1158/1538-7445.PANCA20-PO-011
Published: 13 November 2020
View article titled, Abstract PO-011: Synthetic lethal interaction between the ESCRT paralog enzymes VPS4A and VPS4B in SMAD4 or CDH1-deleted cancers
Journal Articles

Abstract 3400: Adenosine receptor antagonists exhibit potent and selective off-target killing of FOXA1-high cancers

Steven M. Corsello, Ryan D. Spangler, Ranad Humeidi, Caitlin N. Harrington, Rohith T. Nagari, Ritu Singh, Vickie Wang, Mustafa Kocak, Jordan Rossen, Amael Madec, Nancy Dumont, Todd R. Golub
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3400.
https://doi.org/10.1158/1538-7445.AM2020-3400
Published: 15 August 2020
View article titled, Abstract 3400: Adenosine receptor antagonists exhibit potent and selective off-target killing of FOXA1-high cancers
Journal Articles

Abstract LB-053: VPS4A is a synthetic lethal target in VPS4B-deficient cancers due to co-deletion with SMAD4

Jasper E. Neggers, Brenton R. Paolella, Adhana Asfaw, Michael V. Rothberg, Thomas A. Skipper, Radha L. Kalekar, John M. Krill-Burger, Andrew L. Hong, Guillaume Kugener, Jeremie Kalfon, Annan Yang, Chen Yuan, Nancy Dumont, Alfredo Gonzalez, Mai Abdusamad, Yvonne Y. Li, Liam F. Spurr, Westley W. Wu, Federica Piccioni, Brian M. Wolpin, David E. Root, Jesse S. Boehm, Andrew D. Cherniack, Aviad Tsherniak, Todd R. Golub, Francisca Vazquez, Andrew J. Aguirre
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-053.
https://doi.org/10.1158/1538-7445.AM2020-LB-053
Published: 15 August 2020
View article titled, Abstract LB-053: <em>VPS4A</em> is a synthetic lethal target in <em>VPS4B</em>-deficient cancers due to co-deletion with <em>SMAD4</em>
Journal Articles

Abstract 2878: CRISPR-Cas9 screens identify the nuclear export factor NXT1 as a novel therapeutic target in MYCN-amplified neuroblastoma

Clare F. Malone, Neekesh V. Dharia, Guillaume Kugener, Brenton Paolella, Michael Rothberg, Mai Abdusamad, Alfredo Gonzalez, Nancy Dumont, Scott Younger, David Root, Francisca Vazquez, Kimberly Stegmaier
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2878.
https://doi.org/10.1158/1538-7445.AM2019-2878
Published: 01 July 2019
View article titled, Abstract 2878: CRISPR-Cas9 screens identify the nuclear export factor NXT1 as a novel therapeutic target in <em>MYCN-</em>amplified neuroblastoma
Journal Articles

Abstract 2948: Novel cell line barcoding method reveals tepoxalin as a selective drug against MDR1-high tumor cells

Steven M. Corsello, Ryan D. Spangler, Rohith T. Nagari, Mustafa Kocak, Jordan Rossen, Patrick O'Hearn, Jennifer Roth, Alfredo Gonzalez, Nancy Dumont, John Doench, Jesse S. Boehm, Francisca Vazquez, Aviad Tsherniak, Todd R. Golub
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2948.
https://doi.org/10.1158/1538-7445.AM2019-2948
Published: 01 July 2019
View article titled, Abstract 2948: Novel cell line barcoding method reveals tepoxalin as a selective drug against MDR1-high tumor cells
Journal Articles

Abstract LB-061: HER2-targeted PEGylated liposomal doxorubicin (MM-302) efficiently targets the HER2 intermediate cell population in vitro and in vivo

Elena Geretti, Christopher Espelin, Bambang Adiwijaya, Nancy Dumont, Silvia Coma, Zachary Koncki, Minh Pham, Gabriela Garcia, Troy Bloom, Victoria Rimkunas, Joe Reynolds, Karen Campbell, Victor Moyo, Istvan Molnar, Patricia LoRusso, Ian Krop, Kathy Miller, Cynthia Ma, Pamela Munster, Thomas Wickham
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-061.
https://doi.org/10.1158/1538-7445.AM2016-LB-061
Published: 15 July 2016
View article titled, Abstract LB-061: HER2-targeted PEGylated liposomal doxorubicin (MM-302) efficiently targets the HER2 intermediate cell population in vitro and in vivo
Journal Articles

Abstract 4134: MM-302 is more effective than PEGylated liposomal doxorubicin (PLD) at reducing pulmonary metastatic burden in breast cancer models expressing intermediate levels of HER2

Nancy Dumont, Elena Geretti, Shannon Curtis Leonard, Christopher Espelin, Daniel Gaddy, Bart Hendriks, Ulrik Nielsen, Thomas Wickham
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4134.
https://doi.org/10.1158/1538-7445.AM2015-4134
Published: 01 August 2015
View article titled, Abstract 4134: MM-302 is more effective than PEGylated liposomal doxorubicin (PLD) at reducing pulmonary metastatic burden in breast cancer models expressing intermediate levels of HER2
Journal Articles

Abstract P6-11-05: Tumor priming with cyclophosphamide for enhanced tumor delivery, penetration and anti-tumor activity of MM-302, HER2-targeted liposomal doxorubicin

Elena Geretti, Shannon C Leonard, Nancy Dumont, Christopher W Espelin, Daniel F Gaddy, Thomas J Wickham, Bart S Hendriks
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-11-05.
https://doi.org/10.1158/1538-7445.SABCS14-P6-11-05
Published: 01 May 2015
View article titled, Abstract P6-11-05: Tumor priming with cyclophosphamide for enhanced tumor delivery, penetration and anti-tumor activity of MM-302, HER2-targeted liposomal doxorubicin
Journal Articles

Abstract 3271: Tumor priming with cyclophosphamide increases delivery and activity of Her2-targeted liposomal doxorubicin (MM-302) in preclinical models of breast cancer.

Elena Geretti, Shannon C. Leonard, Daniel F. Gaddy, Nancy Dumont, Thomas J. Wickham, Bart S. Hendriks
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3271.
https://doi.org/10.1158/1538-7445.AM2013-3271
Published: 15 April 2013
View article titled, Abstract 3271: Tumor priming with cyclophosphamide increases delivery and activity of Her2-targeted liposomal doxorubicin (MM-302) in preclinical models of breast cancer.
Journal Articles

Abstract LB-273: The tumor suppressor p16INK4a regulates extensive plasticity in rare somatic cells found in adult human tissue.

Somdutta Roy, Philippe Gascard, Nancy Dumont, Jianxin Zhao, Deng Pan, Sarah Petrie, Marta Margeta, Thea Dorothy Tlsty
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-273.
https://doi.org/10.1158/1538-7445.AM2013-LB-273
Published: 15 April 2013
View article titled, Abstract LB-273: The tumor suppressor p16INK4a regulates extensive plasticity in rare somatic cells found in adult human tissue.
Journal Articles

Abstract 5285: Novel antibody-based probes for the detection and study of pre-malignant breast cancer cells

Christopher R. Drake, David Miller, Philippe Gascard, Nancy Dumont, David Tseng, Thea Tisty, Ella F. Jones
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5285.
https://doi.org/10.1158/1538-7445.AM2011-5285
Published: 15 April 2011
View article titled, Abstract 5285: Novel antibody-based probes for the detection and study of pre-malignant breast cancer cells
Journal Articles

Knockdown of the Transforming Growth Factor-β Type III Receptor Impairs Motility and Invasion of Metastatic Cancer Cells

Tracy L. Criswell, Nancy Dumont, Joey V. Barnett, Carlos L. Arteaga
Journal: Cancer Research
Cancer Res (2008) 68 (18): 7304–7312.
https://doi.org/10.1158/0008-5472.CAN-07-6777
Published: 14 September 2008
View article titled, Knockdown of the Transforming Growth Factor-β Type III Receptor Impairs Motility and Invasion of Metastatic Cancer Cells
Open the PDF for Knockdown of the Transforming Growth Factor-β Type III Receptor Impairs Motility and Invasion of Metastatic Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract LB-334: Signals from the microenvironment induce a malignant program accompanied by de novo epigenetic remodeling

Nancy Dumont, Yongping G. Crawford, Paul A. Reynolds, Matthew B. Wilson, Mahvash Sigaroudinia, Mona L. Gauthier, Colleen A. Fordyce, Thea D. Tlsty
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-334.
https://doi.org/10.1158/1538-7445.AM2008-LB-334
Published: 15 May 2008
View article titled, Abstract LB-334: Signals from the microenvironment induce a malignant program accompanied by de novo epigenetic remodeling
Journal Articles

Signals from the microenvironment induce a malignant program accompanied by de novo epigenetic remodeling

Nancy Dumont, Yongping Crawford, Paul Reynolds, Matthew Wilson, Mahvash Sigaroudinia, Mona Gauthier, Colleen Fordyce, Thea Tlsty
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-334.
Published: 01 May 2008
View article titled, Signals from the microenvironment induce a malignant program accompanied by de novo epigenetic remodeling