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Journal Articles

Abstract 2110: Characterization of the correlation between BTK degradation and tumor growth inhibition of the BTK target protein degraders using PK/PD modeling

Yue Wu, Shuran Li, Fan Wang, Nan Hu, Longbo Yin, Xiaomin Song, Jiye Zhang, Aiying Xu, Shasha Yang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2110.
https://doi.org/10.1158/1538-7445.AM2024-2110
Published: 22 March 2024
View article titled, Abstract 2110: Characterization of the correlation between BTK degradation and tumor growth inhibition of the BTK target protein degraders using PK/PD modeling
Journal Articles

Abstract 2461: Discovery of an orally available and liver-targeted ALPK1 agonist for cancer immunotherapy

Yupeng Wang, Nana Du, Xiaona Dong, Xuebing Sun, Yuan Hong, Xiaolong Yang, Zhijiang Ji, Qianyu Wang, Yun Lv, Zhichen Shi, Yajuan Gao, Xiaofu Hou, Yaxin Zhang, Juan Wang, Rui Mao, Yinxin Liu, Liang Li, Jingjin Ding, Hexiang Wang, Nan Hu, Counde O’Yang, Zhihong Li, Keith Bley, Feng Shao
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2461.
https://doi.org/10.1158/1538-7445.AM2024-2461
Published: 22 March 2024
View article titled, Abstract 2461: Discovery of an orally available and liver-targeted ALPK1 agonist for cancer immunotherapy
Journal Articles

Abstract 6158: BGB-24714, a novel oral IAP antagonist, displayed significant anti-tumor activities in preclinical models as a monotherapy and in combination with paclitaxel

Jie Li, Nan Hu, Yilu Zhang, Xiaolong Yang, Minjuan Deng, Wenfeng Gong, Longbo Yin, Yong Liu, Yajuan Gao, Wei Wei, Xing Wang, Xinyi Liang, Yanwen Ma, Xuxing Sang, Chang Liu, Jingyuan Wang, Qianqian Lu, Fengtao Song, Xi Yuan, Yibing Wang, Jing Li, Wei Jin, Xuesong Liu, Xiaomin Song
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6158.
https://doi.org/10.1158/1538-7445.AM2023-6158
Published: 04 April 2023
View article titled, Abstract 6158: BGB-24714, a novel oral IAP antagonist, displayed significant anti-tumor activities in preclinical models as a monotherapy and in combination with paclitaxel
Journal Articles

Abstract 2400: Fucosyltransferase expression is associated with head and neck cancer survival

Kevin Brown Chandler, Brittany Montesino, Nan Hu, Juan M. Lozano, Robert Sackstein
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2400.
https://doi.org/10.1158/1538-7445.AM2022-2400
Published: 15 June 2022
View article titled, Abstract 2400: Fucosyltransferase expression is associated with head and neck cancer survival
Journal Articles

Abstract P3-01-26: Mammographic density in relation to breast cancer risk factors among Chinese women

Hela Koka, Yuan Tian, Deng Lu, Kai Yu, Er-Ni Li, Changyuan Guo, Bin Zhu, Jennifer L Guida, Ariane Chan, Nan Hu, Ning Lu, Gretchen Gierach, Jing Li, Xiaohong R Yang
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-01-26.
https://doi.org/10.1158/1538-7445.SABCS21-P3-01-26
Published: 15 February 2022
View article titled, Abstract P3-01-26: Mammographic density in relation to breast cancer risk factors among Chinese women
Journal Articles

Loss of FBXW7 Correlates with Increased IDH1 Expression in Glioma and Enhances IDH1-Mutant Cancer Cell Sensitivity to Radiation

Zhuo Yang, Nan Hu, Weiwei Wang, Weihua Hu, Shaolong Zhou, Jianxiang Shi, Minghe Li, Zhou Jing, Chao Chen, Xuyang Zhang, Ruyi Yang, Xudong Fu, Xinjun Wang
Journal: Cancer Research
Cancer Res (2022) 82 (3): 497–509.
https://doi.org/10.1158/0008-5472.CAN-21-0384
Published: 02 February 2022
View article titled, Loss of FBXW7 Correlates with Increased IDH1 Expression in Glioma and Enhances IDH1-Mutant Cancer Cell Sensitivity to Radiation
Open the PDF for Loss of FBXW7 Correlates with Increased IDH1 Expression in Glioma and Enhances IDH1-Mutant Cancer Cell Sensitivity to Radiation in another window
Includes: Supplementary data
Journal Articles

Abstract 3077: Preclinical characterization of BGB-11417, a potent and selective Bcl-2 inhibitor with superior antitumor activities in haematological tumor models

Nan Hu, Yunhang Guo, Hai Xue, Ye Liu, Yin Guo, Fan Wang, Xiaomin Song, Ying Guo, Shuaishuai Chen, Haipeng Xu, Taichang Zhang, Yanwen Ma, Xuebing Sun, Yuan Hong, Yutong Zhu, Aiying Xu, Zhenzhen Cheng, Haimei Xing, Zhiwei Wang, Xuesong Liu, Lai Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3077.
https://doi.org/10.1158/1538-7445.AM2020-3077
Published: 15 August 2020
View article titled, Abstract 3077: Preclinical characterization of BGB-11417, a potent and selective Bcl-2 inhibitor with superior antitumor activities in haematological tumor models
Journal Articles

Abstract P5-08-20: Association between quantitative mammographic density and breast cancer subtypes among Chinese breast cancer patients

Xiaohong R Yang, Yuan Tian, Jennifer Guida, Hela Koka, Ariane Chan, Changyuan Guo, Erni Li, Eric Tang, Hyuna Sung, Ning Lu, Nan Hu, Gretchen Gierach, Jing Li
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-08-20.
https://doi.org/10.1158/1538-7445.SABCS19-P5-08-20
Published: 15 February 2020
View article titled, Abstract P5-08-20: Association between quantitative mammographic density and breast cancer subtypes among Chinese breast cancer patients
Journal Articles

Abstract 617: Aggressive phenotypes of luminal breast cancer demonstrate associations with body mass index analogous to triple-negative breast cancer

Mustapha Abubakar, Changyuan Guo, Hela Koka, Bin Zhou, Eric Tang, Joseph Deng, Nan Hu, Ning Lu, Xiaohong R. Yang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 617.
https://doi.org/10.1158/1538-7445.AM2019-617
Published: 01 July 2019
View article titled, Abstract 617: Aggressive phenotypes of luminal breast cancer demonstrate associations with body mass index analogous to triple-negative breast cancer
Journal Articles

Abstract 2905: Clinical features in relation to age at diagnosis in luminal breast cancer patients: A hospital-based case series study in Beijing, China

Hela Koka, Changyuan Guo, Mustapha Abubakar, Hyuna Sung, Hyuna Sung, Bin Zhuo, Eric Tang, Joseph Deng, Nan Hu, Ning Lu, Xiaohong R. Yang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2905.
https://doi.org/10.1158/1538-7445.AM2019-2905
Published: 01 July 2019
View article titled, Abstract 2905: Clinical features in relation to age at diagnosis in luminal breast cancer patients: A hospital-based case series study in Beijing, China
Journal Articles

Abstract 5290: Racial variation in terminal duct lobular unit (TDLU) involution in Chinese and Polish breast cancer patients

Hyuna Sung, Changyuan Guo, Jennifer Guida, Shan Zheng, Erni Li, Jing Li, Nan Hu, Joseph Deng, Montserrat Garcia-Closas, Jonine Figueroa, Mark Sherman, Gretchen Gierach, Ning Lu, Xiaohong R. Yang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5290.
https://doi.org/10.1158/1538-7445.AM2017-5290
Published: 01 July 2017
View article titled, Abstract 5290: Racial variation in terminal duct lobular unit (TDLU) involution in Chinese and Polish breast cancer patients
Journal Articles

Abstract LB-158: Germline mutations in PALB2, BRCA1 and RAD51C observed in gastric cancer cases

Ruta Sahasrabudhe, Paul Lott, Mabel Bohorquez, Ted Toal, Ana Estrada, John Suarez, Alejandro Brea-Fernández, Jose Cameselle-Teijeiro, Carla Pinto, Irma Ramos, Alejandra Mantilla, Rodrigo Prieto, Alejandro Corvalan, Enrique Norero, Carolina Alvarez, Teresa Tapia, Pilar Carvallo, Luz Gonzalez, Alicia Cock-Rada, Angela Solano, Florencia Neffa, Adriana Della Valle, Chris Yau, Gabriela Soares, Alexander Borowsky, Xiao-You Han, Li-JI He, Phillip Taylor, Alisa Goldstein, Nan Hu, Javier Torres, Magdalena Echeverry, Clara Ruiz-Ponte, Manuel Teixeira, Luis G. Carvajal-Carmona
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-158.
https://doi.org/10.1158/1538-7445.AM2017-LB-158
Published: 01 July 2017
View article titled, Abstract LB-158: Germline mutations in <em>PALB2</em>, <em>BRCA1</em> and <em>RAD51C</em> observed in gastric cancer cases
Journal Articles

Abstract 3257: Molecular characterization of the human stomach microbiota in gastric cancer patients

Guoqin Yu, Javier Torres, Nan Hu, Rafael Medrano-Guzman, Roberto Herrera-Goepfert, Michael S. Humphrys, Lemin Wang, Chaoyu Wang, Ti Ding, Jacques Ravel, Philip R. Taylor, Christian Abnet, Alisa Goldstein
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3257.
https://doi.org/10.1158/1538-7445.AM2017-3257
Published: 01 July 2017
View article titled, Abstract 3257: Molecular characterization of the human stomach microbiota in gastric cancer patients
Journal Articles

Abstract 1294: Prevalence and spectrum of germline rare variants in BRCA1/2 and PALB2 among breast cancer cases in Sarawak, Malaysia

Xiaohong (Rose) Yang, Beena Devi, Hyuna Sung, Jennifer Guida, Yanzi Xiao, Lisa Garland, Nan Hu, Maria Rodriguez-Herrera, Chaoyu Wang, Kristine Jones, Wen Luo, Belynda Hicks, Tieng Swee Tang, Karobi Moitra, Mike Dean
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1294.
https://doi.org/10.1158/1538-7445.AM2017-1294
Published: 01 July 2017
View article titled, Abstract 1294: Prevalence and spectrum of germline rare variants in <em>BRCA1/2</em> and <em>PALB2</em> among breast cancer cases in Sarawak, Malaysia
Journal Articles

Abstract 2010: BTK inhibitor BGB-3111 demonstrates anti-tumor activity in solid tumor models

Nan Hu, Jiye Zhang, Min He, Shuo Zhang, Yong Liu, Lai Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2010.
https://doi.org/10.1158/1538-7445.AM2017-2010
Published: 01 July 2017
View article titled, Abstract 2010: BTK inhibitor BGB-3111 demonstrates anti-tumor activity in solid tumor models
Journal Articles

Abstract 4796: BTK inhibitor BGB-3111 synergizes with lenalidomide in MCL models

Nan Hu, Shuo Zhang, Min He, Jiye Zhang, Bin Jiang, Zhijian Sun, Lusong Luo, Lai Wang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4796.
https://doi.org/10.1158/1538-7445.AM2016-4796
Published: 15 July 2016
View article titled, Abstract 4796: BTK inhibitor BGB-3111 synergizes with lenalidomide in MCL models
Journal Articles

Abstract 2561: Integrated analysis of ESCC tumor/normal tissues and patient blood samples using expression, genotypes and DNA somatic change data

Howard H. Yang, Hua Su, Huaitian Liu, Nan Hu, Chaoyu Wang, Lemin Wang, Ti Ding, Carol Giffen, Alisa M. Goldstein, Philip R. Taylor, Maxwell P. Lee
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2561.
https://doi.org/10.1158/1538-7445.AM2016-2561
Published: 15 July 2016
View article titled, Abstract 2561: Integrated analysis of ESCC tumor/normal tissues and patient blood samples using expression, genotypes and DNA somatic change data
Journal Articles

Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer

Nan Hu, Mitsutaka Kadota, Huaitian Liu, Christian C. Abnet, Hua Su, Hailong Wu, Neal D. Freedman, Howard H. Yang, Chaoyu Wang, Chunhua Yan, Lemin Wang, Sheryl Gere, Amy Hutchinson, Guohong Song, Yuan Wang, Ti Ding, You-Lin Qiao, Jill Koshiol, Sanford M. Dawsey, Carol Giffen, Alisa M. Goldstein, Philip R. Taylor, Maxwell P. Lee
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (7): 1714–1723.
https://doi.org/10.1158/0008-5472.CAN-15-0338
Published: 31 March 2016
View article titled, Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Open the PDF for Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2589: Investigations of covalent binding efficiency for third-generation EGFR irreversible inhibitors AZD9291 and CO-1686

Zhen Qin, Xuebing Sun, Ye Liu, Yunguang Du, Miao Wang, Nan Hu, Jiye Zhang, Hao Peng, Lai Wang, Min Wei, Lusong Luo
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2589.
https://doi.org/10.1158/1538-7445.AM2015-2589
Published: 01 August 2015
View article titled, Abstract 2589: Investigations of covalent binding efficiency for third-generation EGFR irreversible inhibitors AZD9291 and CO-1686
Journal Articles

Abstract 4622: Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers

Hyuna Sung, Howard H. Yang, Han Zhang, Qi Yang, Nan Hu, Ze-Zhong Tang, Hua Su, Lemin Wang, Chaoyu Wang, Ti Ding, Jin-Hu Fan, You-Lin Qiao, William Wheeler, Carol Giffen, Laurie Burdett, Zhaoming Wang, Maxwell P. Lee, Stephen J. Chanock, Sanford M. Dawsey, Neal D. Freedman, Christian C. Abnet, Alisa M. Goldstein, Kai Yu, Philip R. Taylor, Paula L. Hyland
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4622.
https://doi.org/10.1158/1538-7445.AM2015-4622
Published: 01 August 2015
View article titled, Abstract 4622: Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers