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Nadia Zaffaroni
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Journal Articles

Abstract 2995: The ectopic expression of miR-380-5p interferes with the aggressive traits of diffuse malignant peritoneal mesothelima cells

Stefano Percio, Lorenzo Di Pietro, Eisa Naghshineh, Marcello Deraco, Nadia Zaffaroni, Marco Folini
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2995.
https://doi.org/10.1158/1538-7445.AM2024-2995
Published: 22 March 2024
View article titled, Abstract 2995: The ectopic expression of miR-380-5p interferes with the aggressive traits of diffuse malignant peritoneal mesothelima cells
Journal Articles

Abstract 4642: Fatty acid synthase as a novel prognostic biomarker and a potential therapeutic target in diffuse malignant peritoneal mesothelioma

Valentina Doldi, Silvia Martini, Chiara Maura Ciniselli, Alessia Beretta, Marcello Deraco, Shigeki Kusamura, Dario Baratti, Paolo Gandellini, Paolo Verderio, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4642.
https://doi.org/10.1158/1538-7445.AM2024-4642
Published: 22 March 2024
View article titled, Abstract 4642: Fatty acid synthase as a novel prognostic biomarker and a potential therapeutic target in diffuse malignant peritoneal mesothelioma
Journal Articles

Abstract 5922: Characterization of the biological effects of a quadruplex-interacting molecule in dedifferentiated liposarcoma cells

Eisa Naghshineh, Beatrice Tosoni, Lorenzo Di Pietro, Sandro Pasquali, Nadia Zaffaroni, Stephen Neidle, Sara N. Richter, Marco Folini
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5922.
https://doi.org/10.1158/1538-7445.AM2024-5922
Published: 22 March 2024
View article titled, Abstract 5922: Characterization of the biological effects of a quadruplex-interacting molecule in dedifferentiated liposarcoma cells
Journal Articles

Abstract 2504: Antiarrhythmic drugs repositioning to counteract the activated phenotype of prostate cancer-associated fibroblasts

Valentina Doldi, Monica Tortoreto, Stefano Percio, Paolo Gandellini, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2504.
https://doi.org/10.1158/1538-7445.AM2023-2504
Published: 04 April 2023
View article titled, Abstract 2504: Antiarrhythmic drugs repositioning to counteract the activated phenotype of prostate cancer-associated fibroblasts
Journal Articles

Abstract 2245: The transcriptomic profile of retroperitoneal primary well differentiated liposarcoma (WDLPS) and well differentiated (WD)/dedifferentiated (DD) components of DD liposarcoma (DDLPS) reveals the progression from WDLPS to DDLPS

Sandro Pasquali, Stefano Percio, Dario Callegaro, Silvia Martini, Alessia Beretta, Alessia Bertolotti, Silvia Brich, Paola Collini, Marta Barisella, Loris De Cecco, Viviana Vallacchi, Silvia Stacchiotti, Matteo Benelli, Alessandro Gronchi, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2245.
https://doi.org/10.1158/1538-7445.AM2023-2245
Published: 04 April 2023
View article titled, Abstract 2245: The transcriptomic profile of retroperitoneal primary well differentiated liposarcoma (WDLPS) and well differentiated (WD)/dedifferentiated (DD) components of DD liposarcoma (DDLPS) reveals the progression from WDLPS to DDLPS
Journal Articles

Abstract 6726: Effectiveness of irinotecan plus trabectedin in a desmoplastic small round cell tumor patient-derived xenograft

Valentina Zuco, Sandro Pasquali, Monica Tortoreto, Stefano Percio, Valentina Doldi, Marta Barisella, Paola Collini, Gianpaolo Dagrada, Silvia Brich, Patrizia Gasparini, Marco Fiore, Michela Casanova, Anna Maria Frezza, Alessandro Gronchi, Silvia Stacchiotti, Andrea Ferrari, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6726.
https://doi.org/10.1158/1538-7445.AM2023-6726
Published: 04 April 2023
View article titled, Abstract 6726: Effectiveness of irinotecan plus trabectedin in a desmoplastic small round cell tumor patient-derived xenograft
Journal Articles

Abstract A032: miR-205 reconstitution sensitizes prostate cancer cells and xenografts to radiotherapy, through PKCε suppression

Paolo Gandellini, Rihan El Bezawy, Marco Folini, Denis Cominetti, Stella Tinelli, Tiziana Rancati, Riccardo Valdagni, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): A032.
https://doi.org/10.1158/1538-7445.PRCA2017-A032
Published: 14 August 2018
View article titled, Abstract A032: miR-205 reconstitution sensitizes prostate cancer cells and xenografts to radiotherapy, through PKCε suppression
Journal Articles

Abstract 5452: Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: Persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism

Rihan El Bezawy, Michelandrea De Cesare, Marzia Pennati, Marcello Deraco, Paolo Gandellini, Valentina Zuco, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5452.
https://doi.org/10.1158/1538-7445.AM2017-5452
Published: 01 July 2017
View article titled, Abstract 5452: Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: Persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism
Journal Articles

Abstract 1070: Role of FOXO1 in response of ovarian carcinoma cells to the XPO1/CRM1 inhibitor KPT-330/selinexor in combination with cisplatin

Simone Stucchi, Michelandrea De Cesare, Cristina Corno, Nives Carenini, Emilio Ciusani, Nadia Zaffaroni, Laura Gatti, Paola Perego
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1070.
https://doi.org/10.1158/1538-7445.AM2017-1070
Published: 01 July 2017
View article titled, Abstract 1070: Role of FOXO1 in response of ovarian carcinoma cells to the XPO1/CRM1 inhibitor KPT-330/selinexor in combination with cisplatin
Journal Articles

Abstract 3289: Microenvironment modulation and enhancement of cytotoxic therapy by the heparanase inhibitor Roneparstat against human B-non Hodgkin lymphomas

Massimo Di Nicola, Franco Zunino, Anna Rossini, Giusi Ruggiero, Micheleandrea De Cesare, Denis Cominetti, Monica Tortoreto, Cinzia Lanzi, Giuliana Cassinelli, Roberta Zappasodi, Claudio Tripodo, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3289.
https://doi.org/10.1158/1538-7445.AM2016-3289
Published: 15 July 2016
View article titled, Abstract 3289: Microenvironment modulation and enhancement of cytotoxic therapy by the heparanase inhibitor Roneparstat against human B-non Hodgkin lymphomas
Journal Articles

Abstract 332: Spliceosome inhibition as novel strategy against diffuse malignant peritoneal mesothelioma

Rocco Sciarrillo, Valentina E. Gomez, Marzia Pennati, Anna Wojtuszkiewicz, Gert-Jan L. Kaspers, Carla Molthoff, Nadia Zaffaroni, Godefridus J. Peters, Gerrit Jansen, Elisa Giovannetti
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 332.
https://doi.org/10.1158/1538-7445.AM2016-332
Published: 15 July 2016
View article titled, Abstract 332: Spliceosome inhibition as novel strategy against diffuse malignant peritoneal mesothelioma
Journal Articles

Abstract 3113: SMO mutation identifies a subgroup of malignant pleural mesothelioma (MPM) patients with a worse prognosis

Monica Ganzinelli, Claudia Proto, Diego Signorelli, Laura Botta, Giulia Pasello, Marcello Tiseo, Annalisa Trama, Gemma Gatta, Adele Busico, Alessandra Fabbri, Nadia Zaffaroni, Giuseppe Pelosi, Ugo Pastorino, Filippo De Braud, Milena Vitali, Marina C. Garassino
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3113.
https://doi.org/10.1158/1538-7445.AM2016-3113
Published: 15 July 2016
View article titled, Abstract 3113: SMO mutation identifies a subgroup of malignant pleural mesothelioma (MPM) patients with a worse prognosis
Journal Articles

Abstract 19: Antitumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin

Nadia Zaffaroni, Michelandrea De Cesare, Denis Cominetti, Valentina Doldi, Alessia Lopergolo, Marcello Deraco, Paolo Gandellini, Yosef Landesman, Sharon Friedlander, Michael G. Kauffman, Sharon Shacham, Marzia Pennati
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 19.
https://doi.org/10.1158/1538-7445.AM2015-19
Published: 01 August 2015
View article titled, Abstract 19: Antitumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin
Journal Articles

Abstract B18: MiR-205 puts the brakes on the malignant interplay between prostate cancer cells and associated fibroblasts

Paolo Gandellini, Elisa Giannoni, Anna Casamichele, Maria Letizia Taddei, Maurizio Callari, Riccardo Valdagni, Nadia Zaffaroni, Paola Chiarugi
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): B18.
https://doi.org/10.1158/1538-7445.TIM2013-B18
Published: 01 May 2014
View article titled, Abstract B18: MiR-205 puts the brakes on the malignant interplay between prostate cancer cells and associated fibroblasts
Journal Articles

Abstract 3440: CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce the incidence of tumor spreading and improve overall survival in preclinical models of prostate cancer.

Giovanni Luca Gravina, Monica Tortoreto, Andrea Mancini, Paola Muzi, Luca Ventura, Sandra D'ascenzo, Alessandro Addis, Yosef Landesman, Dilara McCauley, Vincenza Dolo, Michael Kauffman, Sharon Shacham, Nadia Zaffaroni, Claudio Festuccia
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3440.
https://doi.org/10.1158/1538-7445.AM2013-3440
Published: 15 April 2013
View article titled, Abstract 3440: CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce the incidence of tumor spreading and improve overall survival in preclinical models of prostate cancer.
Journal Articles

Abstract LB-433: Biomarker analysis and final results of INT70/09 Phase II proof-of-concept study of Pazopanib (PZP) in refractory urothelial cancer (UC)

Andrea Necchi, Nadia Zaffaroni, Luigi Mariani, Nicola Nicolai, Flavio Crippa, Carlo Morosi, Maria Grazia Daidone, Alessandro Massimo Gianni, Filippo De Braud, Roberto Salvioni
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-433.
https://doi.org/10.1158/1538-7445.AM2012-LB-433
Published: 15 April 2012
View article titled, Abstract LB-433: Biomarker analysis and final results of INT70/09 Phase II proof-of-concept study of Pazopanib (PZP) in refractory urothelial cancer (UC)
Journal Articles

TLR9 Agonists Oppositely Modulate DNA Repair Genes in Tumor versus Immune Cells and Enhance Chemotherapy Effects

Michele Sommariva, Loris De Cecco, Michelandrea De Cesare, Lucia Sfondrini, Sylvie Ménard, Cecilia Melani, Domenico Delia, Nadia Zaffaroni, Graziella Pratesi, Valentina Uva, Elda Tagliabue, Andrea Balsari
Journal: Cancer Research
Cancer Res (2011) 71 (20): 6382–6390.
https://doi.org/10.1158/0008-5472.CAN-11-1285
Published: 12 October 2011
View article titled, TLR9 Agonists Oppositely Modulate DNA Repair Genes in Tumor versus Immune Cells and Enhance Chemotherapy Effects
Open the PDF for TLR9 Agonists Oppositely Modulate DNA Repair Genes in Tumor versus Immune Cells and Enhance Chemotherapy Effects in another window
Includes: Supplementary data
Journal Articles

Abstract 1186: PTEN expression predicts biochemical recurrence in prostate cancer

Steven Stone, Zaina Sangale, Silvia Veneroni, Julia Reid, Maurizio Colecchia, Amy Carlson, Riccardo Valdagni, Alexander Gutin, Maria G. Daidone, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1186.
https://doi.org/10.1158/1538-7445.AM10-1186
Published: 15 April 2010
View article titled, Abstract 1186: PTEN expression predicts biochemical recurrence in prostate cancer
Journal Articles

miR-205 Exerts Tumor-Suppressive Functions in Human Prostate through Down-regulation of Protein Kinase Cε

Paolo Gandellini, Marco Folini, Nicole Longoni, Marzia Pennati, Mara Binda, Maurizio Colecchia, Roberto Salvioni, Rosanna Supino, Roberta Moretti, Patrizia Limonta, Riccardo Valdagni, Maria Grazia Daidone, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2287–2295.
https://doi.org/10.1158/0008-5472.CAN-08-2894
Published: 17 March 2009
View article titled, miR-205 Exerts Tumor-Suppressive Functions in Human Prostate through Down-regulation of Protein Kinase Cε
Open the PDF for miR-205 Exerts Tumor-Suppressive Functions in Human Prostate through Down-regulation of Protein Kinase Cε in another window
Includes: Supplementary data
Journal Articles

Novel anthracene derivatives as telomerase inhibitors

Claudia Pivetta, Giuseppe Zagotto, Nadia Zaffaroni, Manlio Palumbo, Claudia Sissi
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2329.
Published: 01 May 2008
View article titled, Novel anthracene derivatives as telomerase inhibitors