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Myoung Sook Kim
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Journal Articles

Abstract 794: Inhibition of mitochondrial metabolism by a novel agent targeting RUNX2-DNA binding in breast cancer

Myoung Sook Kim, Ramkishore Gernapudi, Yessenia C. Cedeno, Brian M. Polster, Geoffrey D. Girnun, Antonino Passaniti
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 794.
https://doi.org/10.1158/1538-7445.AM2019-794
Published: 01 July 2019
View article titled, Abstract 794: Inhibition of mitochondrial metabolism by a novel agent targeting RUNX2-DNA binding in breast cancer
Journal Articles

Abstract 963: Epigenetic silencing of cancer-specific methylation may converge on therapeutic targets on human cancers

Keishi Yamashita, Myoung Sook Kim, Akira Ooki, Hiroshi Kato, Mina Waraya, Hiroshi Kawamata, Masahiko Watanabe, David Sidransky
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 963.
https://doi.org/10.1158/1538-7445.AM2012-963
Published: 15 April 2012
View article titled, Abstract 963: Epigenetic silencing of cancer-specific methylation may converge on therapeutic targets on human cancers
Journal Articles

Abstract LB-341: Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers

Mariana Brait, Shizhang Ling, Jatin Nagpal, Xiaofei Chang, Hannah Park, Juna Lee, Jun Okamura, Keishi Yamashita, David Sidransky, Myoung Sook Kim
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-341.
https://doi.org/10.1158/1538-7445.AM2012-LB-341
Published: 15 April 2012
View article titled, Abstract LB-341: Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers
Journal Articles

Abstract 2703: Loss of dependence on EGFR signaling by upregulation of Mig6 confers drug resistance to erlotinib

Xiaofei Chang, Aditi Chatterjee, Shyhmin Huang, Myoung Sook Kim, Chunbo Shao, Constance L. Monitto, Patrick K. Ha, Manuel Hidalgo, Paul M. Harari, David M. Berman, Atul Bedi, David Sidransky
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2703.
https://doi.org/10.1158/1538-7445.AM10-2703
Published: 15 April 2010
View article titled, Abstract 2703: Loss of dependence on EGFR signaling by upregulation of Mig6 confers drug resistance to erlotinib
Journal Articles

Abstract 5067: Neurofilament heavy polypeptide regulates the Akt-β-catenin pathway in human esophageal squamous cell carcinoma

Myoung Sook Kim, Xiaofei Chang, Cynthia LeBron, Jatin K. Nagpal, Juna Lee, Yiping Huang, Keishi Yamashita, Barry Trink, Edward A. Ratovitski, David Sidransky
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5067.
https://doi.org/10.1158/1538-7445.AM10-5067
Published: 15 April 2010
View article titled, Abstract 5067: Neurofilament heavy polypeptide regulates the Akt-β-catenin pathway in human esophageal squamous cell carcinoma
Journal Articles

Identification of Hypermethylated Genes Associated with Cisplatin Resistance in Human Cancers

Xiaofei Chang, Constance L. Monitto, Semra Demokan, Myoung Sook Kim, Steven S. Chang, Xiaoli Zhong, Joseph A. Califano, David Sidransky
Journal: Cancer Research
Cancer Res (2010) 70 (7): 2870–2879.
https://doi.org/10.1158/0008-5472.CAN-09-3427
Published: 31 March 2010
View article titled, Identification of Hypermethylated Genes Associated with Cisplatin Resistance in Human Cancers
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Includes: Supplementary data
Journal Articles

Abstract #1336: Promoter DNA methylation of HOP (homeobox only protein) identified by pharmacological unmasking microarray has a great potential of clinical utility as an aggressive marker in gastric cancer

Keishi Yamashita, Akira Ooki, Masaki Mori, Myoung Sook Kim, David Sidransky, Masahiko Watanabe
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1336.
Published: 01 May 2009
View article titled, Abstract #1336: Promoter DNA methylation of HOP (homeobox only protein) identified by pharmacological unmasking microarray has a great potential of clinical utility as an aggressive marker in gastric cancer
Journal Articles

Aberrant hypermethylation in the dfna5 gene promoter increases risk of lymph node metastasis in human breast cancer

Myoung Sook Kim, Cynthia Lebron, Jatin Nagpal, Young Chae, Xiaofei Chang, Yiping Huang, Keishi Yamashita, Barry Trink, Edward Ratovitski, David Sidransky
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2631.
Published: 01 May 2008
View article titled, Aberrant hypermethylation in the <em>dfna5 g</em>ene promoter increases risk of lymph node metastasis in human breast cancer
Journal Articles

Genome-Wide Promoter Analysis Uncovers Portions of the Cancer Methylome

Mohammad Obaidul Hoque, Myoung Sook Kim, Kimberly Laskie Ostrow, Junwei Liu, G. Bea A. Wisman, Hannah Lui Park, Maria Luana Poeta, Carmen Jeronimo, Rui Henrique, Ágnes Lendvai, Ed Schuuring, Shahnaz Begum, Eli Rosenbaum, Maté Ongenaert, Keishi Yamashita, Joseph Califano, William Westra, Ate G.J. van der Zee, Wim Van Criekinge, David Sidransky
Journal: Cancer Research
Cancer Res (2008) 68 (8): 2661–2670.
https://doi.org/10.1158/0008-5472.CAN-07-5913
Published: 15 April 2008
View article titled, Genome-Wide Promoter Analysis Uncovers Portions of the Cancer Methylome
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Includes: Supplementary data
Journal Articles

LOXL1 and LOXL4 Are Epigenetically Silenced and Can Inhibit Ras/Extracellular Signal-Regulated Kinase Signaling Pathway in Human Bladder Cancer

Guojun Wu, Zhongmin Guo, Xiaofei Chang, Myoung Sook Kim, Jatin K. Nagpal, Junwei Liu, Joni M. Maki, Kari I. Kivirikko, Stephen P. Ethier, Barry Trink, David Sidransky
Journal: Cancer Research
Cancer Res (2007) 67 (9): 4123–4129.
https://doi.org/10.1158/0008-5472.CAN-07-0012
Published: 04 May 2007
View article titled, <em>LOXL1</em> and <em>LOXL4</em> Are Epigenetically Silenced and Can Inhibit Ras/Extracellular Signal-Regulated Kinase Signaling Pathway in Human Bladder Cancer
Open the PDF for <em>LOXL1</em> and <em>LOXL4</em> Are Epigenetically Silenced and Can Inhibit Ras/Extracellular Signal-Regulated Kinase Signaling Pathway in Human Bladder Cancer in another window
Includes: Supplementary data
Journal Articles

Overexpression of Glycosylphosphatidylinositol (GPI) Transamidase Subunits Phosphatidylinositol Glycan Class T and/or GPI Anchor Attachment 1 Induces Tumorigenesis and Contributes to Invasion in Human Breast Cancer

Guojun Wu, Zhongmin Guo, Aditi Chatterjee, Xin Huang, Ethel Rubin, Feng Wu, Elizabeth Mambo, Xiaofei Chang, Motonobu Osada, Myoung Sook Kim, Chulso Moon, Joseph A. Califano, Edward A. Ratovitski, Susanne M. Gollin, Saraswati Sukumar, David Sidransky, Barry Trink
Journal: Cancer Research
Cancer Res (2006) 66 (20): 9829–9836.
https://doi.org/10.1158/0008-5472.CAN-06-0506
Published: 17 October 2006
View article titled, Overexpression of Glycosylphosphatidylinositol (GPI) Transamidase Subunits Phosphatidylinositol Glycan Class T and/or GPI Anchor Attachment 1 Induces Tumorigenesis and Contributes to Invasion in Human Breast Cancer
Open the PDF for Overexpression of Glycosylphosphatidylinositol (GPI) Transamidase Subunits Phosphatidylinositol Glycan Class T and/or GPI Anchor Attachment 1 Induces Tumorigenesis and Contributes to Invasion in Human Breast Cancer in another window
Includes: Supplementary data
Journal Articles

LKB1/STK11 Suppresses Cyclooxygenase-2 Induction and Cellular Invasion through PEA3 in Lung Cancer

Sunil Upadhyay, Chunyan Liu, Aditi Chatterjee, Mohammad O. Hoque, Myoung Sook Kim, James Engles, William Westra, Barry Trink, Edward Ratovitski, David Sidransky
Journal: Cancer Research
Cancer Res (2006) 66 (16): 7870–7879.
https://doi.org/10.1158/0008-5472.CAN-05-2902
Published: 15 August 2006
View article titled, LKB1/STK11 Suppresses Cyclooxygenase-2 Induction and Cellular Invasion through PEA3 in Lung Cancer
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Includes: Supplementary data
Journal Articles

Potential oncoprotein AQP5, triggering Ras signal pathway

Janghee Woo, Myoung Sook Kim, Jin Hyen Baek, Minjoo Park, Barry Trink, Edward Ratovitski, David Sidransky, Chulso Moon
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1133.
Published: 15 April 2006
View article titled, Potential oncoprotein AQP5, triggering Ras signal pathway
Journal Articles

DCC promoter hypermethylation in esophageal squamous cell carcinoma

Hannah Lui Park, Keishi Yamashita, Myoung Sook Kim, William H. Westra, Andre Lopes Carvalho, Jin Hyen Baek, Wei Wen Jiang, Jun-Wei Liu, Motonobu Osada, Joseph A. Califano, Masaki Mori, David Sidransky
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 8.
Published: 15 April 2006
View article titled, DCC promoter hypermethylation in esophageal squamous cell carcinoma
Journal Articles

NMDA receptor type 2A at 16p13 is epigenetically inactivated in human colorectal carcinoma

Myoung Sook Kim, Junwei Liu, Keishi Yamashita, Xiaofei Chang, Jin Hyen Baek, Hannah L. Park, Jang- Hee Woo, Motonobu Osada, Sunil Upadhyay, Chulso Moon, David Sidransky
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 13.
Published: 15 April 2006
View article titled, NMDA receptor type 2A at 16p13 is epigenetically inactivated in human colorectal carcinoma
Journal Articles

N-Methyl-d-Aspartate Receptor Type 2B Is Epigenetically Inactivated and Exhibits Tumor-Suppressive Activity in Human Esophageal Cancer

Myoung Sook Kim, Keishi Yamashita, Jin Hyen Baek, Hannah Lui Park, Andre Lopes Carvalho, Motonobu Osada, Mohammad Obaidul Hoque, Sunil Upadhyay, Masaki Mori, Chulso Moon, David Sidransky
Journal: Cancer Research
Cancer Res (2006) 66 (7): 3409–3418.
https://doi.org/10.1158/0008-5472.CAN-05-1608
Published: 03 April 2006
View article titled, <em>N-</em>Methyl-<sc>d</sc>-Aspartate Receptor Type 2B Is Epigenetically Inactivated and Exhibits Tumor-Suppressive Activity in Human Esophageal Cancer
Open the PDF for <em>N-</em>Methyl-<sc>d</sc>-Aspartate Receptor Type 2B Is Epigenetically Inactivated and Exhibits Tumor-Suppressive Activity in Human Esophageal Cancer in another window
Includes: Supplementary data
Journal Articles

PGP9.5 Methylation in Diffuse-Type Gastric Cancer

Keishi Yamashita, Hannah Lui Park, Myoung Sook Kim, Motonobu Osada, Yutaka Tokumaru, Hiroshi Inoue, Masaki Mori, David Sidransky
Journal: Cancer Research
Cancer Res (2006) 66 (7): 3921–3927.
https://doi.org/10.1158/0008-5472.CAN-05-1511
Published: 03 April 2006
View article titled, PGP9.5 Methylation in Diffuse-Type Gastric Cancer
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Includes: Supplementary data
Journal Articles

PGP9.5 Promoter Methylation Is an Independent Prognostic Factor for Esophageal Squamous Cell Carcinoma

Diana L. Mandelker, Keishi Yamashita, Yutaka Tokumaru, Koshi Mimori, David L. Howard, Yoichi Tanaka, Andre Lopes Carvalho, Wei-Wen Jiang, Hannah Lui Park, Myoung Sook Kim, Motonobu Osada, Masaki Mori, David Sidransky
Journal: Cancer Research
Cancer Res (2005) 65 (11): 4963–4968.
https://doi.org/10.1158/0008-5472.CAN-04-3923
Published: 01 June 2005
View article titled, PGP9.5 Promoter Methylation Is an Independent Prognostic Factor for Esophageal Squamous Cell Carcinoma
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Journal Articles

How could DNA promoter methylation apply for cancer clinics?

Keishi Yamashita, Yutaka Tokumaru, Myoung Sook Kim, Hannah Lui Park, Diana L. Mandelker, David Sidransky
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 651.
Published: 01 May 2005
View article titled, How could DNA promoter methylation apply for cancer clinics?
Journal Articles

Inhibition of Histone Deacetylase Increases Cytotoxicity to Anticancer Drugs Targeting DNA

Myoung Sook Kim, Mellissa Blake, Jin Hyen Baek, Glenda Kohlhagen, Yves Pommier, France Carrier
Journal: Cancer Research
Cancer Res (2003) 63 (21): 7291–7300.
Published: 11 November 2003
View article titled, Inhibition of Histone Deacetylase Increases Cytotoxicity to Anticancer Drugs Targeting DNA
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