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Murray Korc
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Journal Articles

Abstract 2449: FGFR4 inhibitor BLU9931 induces cellular senescence in pancreatic ductal adenocarcinoma cell lines promoting sensitivity to senolytic therapy

Norihiko Sasaki, Fujiya Gomi, Hisashi Yoshimura, Masami Yamamoto, Yoko Matsuda, Masaki Michishita, Hitoshi Hatakeyama, Yoichi Kawano, Yoko Itakura, Masashi Toyoda, Murray Korc, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2449.
https://doi.org/10.1158/1538-7445.AM2021-2449
Published: 01 July 2021
View article titled, Abstract 2449: FGFR4 inhibitor BLU9931 induces cellular senescence in pancreatic ductal adenocarcinoma cell lines promoting sensitivity to senolytic therapy
Journal Articles

Abstract C31: The glycosaminoglycan syndecan-4 facilitates pancreatic cancer progression and biologic aggressiveness

Samantha McElyea, Murray Korc
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): C31.
https://doi.org/10.1158/1538-7445.PANCA19-C31
Published: 13 December 2019
View article titled, Abstract C31: The glycosaminoglycan syndecan-4 facilitates pancreatic cancer progression and biologic aggressiveness
Journal Articles

Abstract 4862: Protein arginine methyltransferase 5 as a tumor promoter and therapeutic target in gastrointestinal cancers

Lakshmi Prabhu, Lan Chen, Ahmad Safa, Murray Korc, Zhong-Yin Zhang, Tao Lu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4862.
https://doi.org/10.1158/1538-7445.AM2018-4862
Published: 01 July 2018
View article titled, Abstract 4862: Protein arginine methyltransferase 5 as a tumor promoter and therapeutic target in gastrointestinal cancers
Journal Articles

Abstract 2917: Differentiation therapy and the mechanisms that terminate malignant proliferation

Francis O. Enane, Xiaorong Gu, Murray Korc, Yogen Saunthararajah
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2917.
https://doi.org/10.1158/1538-7445.AM2018-2917
Published: 01 July 2018
View article titled, Abstract 2917: Differentiation therapy and the mechanisms that terminate malignant proliferation
Journal Articles

Abstract 4079: Perturbations in tat-interacting protein 30 (TIP30) levels contribute to pancreatic cancer aggressiveness

Imade E. Imasuen-Williams, Francis Enane, Murray Korc
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4079.
https://doi.org/10.1158/1538-7445.AM2018-4079
Published: 01 July 2018
View article titled, Abstract 4079: Perturbations in tat-interacting protein 30 (TIP30) levels contribute to pancreatic cancer aggressiveness
Journal Articles

Abstract B51: Regulation of HIF1α under hypoxia by APE1/Ref-1 impacts CA9 expression: Dual-targeting in patient-derived 3D pancreatic cancer models

Derek P. Logsdon, Michelle Grimard, Safi Shahda, Nicholas Zyromski, Ernestina Schipani, Fabrizio Carta, Claudiu T. Supuran, Murray Korc, Mircea Ivan, Mark R. Kelley, Melissa L. Fishel
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B51.
https://doi.org/10.1158/1538-7445.PANCA16-B51
Published: 14 December 2016
View article titled, Abstract B51: Regulation of HIF1α under hypoxia by APE1/Ref-1 impacts CA9 expression: Dual-targeting in patient-derived 3D pancreatic cancer models
Journal Articles

Abstract 3400: An angiogenesis gene signature points to active TGF-beta/JAK signaling pathways in a subset of human pancreatic ductal adenocarcinoma cancer patients that are distinct from pathways in pancreatic neuroendocrine tumors

Kelly E. Craven, Jesse Gore, Julie L. Wilson, Murray Korc
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3400.
https://doi.org/10.1158/1538-7445.AM2016-3400
Published: 15 July 2016
View article titled, Abstract 3400: An angiogenesis gene signature points to active TGF-beta/JAK signaling pathways in a subset of human pancreatic ductal adenocarcinoma cancer patients that are distinct from pathways in pancreatic neuroendocrine tumors
Journal Articles

Abstract 4180: TGF-beta promotes angiogenesis in an RB-deficient, Kras-driven mouse model of pancreatic cancer

Jesse Gore, Kelly E. Craven, Julie L. Wilson, Murray Korc
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4180.
https://doi.org/10.1158/1538-7445.AM2015-4180
Published: 01 August 2015
View article titled, Abstract 4180: TGF-beta promotes angiogenesis in an RB-deficient, Kras-driven mouse model of pancreatic cancer
Journal Articles

Abstract 172: Pathophysiological role of microRNA-29 in pancreatic cancer stroma

Jason J. Kwon, Sarah C. Nabinger, Ravi K. Alluri, Zachary Vega, Smiti S. Sahu, Zahi Abdul Sater, Zhangsheng Yu, A Jesse Gore, Grzegorz Nalepa, Romil Saxena, Murray Korc, Janaiah Kota
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 172.
https://doi.org/10.1158/1538-7445.AM2015-172
Published: 01 August 2015
View article titled, Abstract 172: Pathophysiological role of microRNA-29 in pancreatic cancer stroma
Journal Articles

Abstract B19: Redox factor 1 (Ref-1) signaling in the interaction between pancreatic tumor cells and cancer-associated fibroblasts

Melissa L. Fishel, Huiwen Cheng, Murray Korc, Mark R. Kelley
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B19.
https://doi.org/10.1158/1538-7445.PANCA2014-B19
Published: 30 June 2015
View article titled, Abstract B19: Redox factor 1 (Ref-1) signaling in the interaction between pancreatic tumor cells and cancer-associated fibroblasts
Journal Articles

Abstract 969: TGF-beta cross-talks with the EGF receptor family to promote proliferation of pancreatic cancer cells with dysfunctional RB

Jesse Gore, Samantha L. Deitz, Julie L. Wilson, Murray Korc
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 969.
https://doi.org/10.1158/1538-7445.AM2014-969
Published: 01 October 2014
View article titled, Abstract 969: TGF-beta cross-talks with the EGF receptor family to promote proliferation of pancreatic cancer cells with dysfunctional RB
Journal Articles

Abstract 4961: Longitudinal bioluminescence imaging of primary versus abdominal metastatic tumor growth in orthotopic pancreatic tumor models in NOD/SCIDγ(-/-) mice

Harlan E. Shannon, Melissa L. Fishel, Jingwu Xie, Dongsheng Gu, Brian P. McCarthy, Amanda A. Riley, Anthony L. Sinn, Jayne M. Silver, Mark R. Kelley, Helmut Hanenberg, Murray Korc, Karen E. Pollok, Paul R. Territo
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4961.
https://doi.org/10.1158/1538-7445.AM2014-4961
Published: 01 October 2014
View article titled, Abstract 4961: Longitudinal bioluminescence imaging of primary versus abdominal metastatic tumor growth in orthotopic pancreatic tumor models in NOD/SCIDγ(-/-) mice
Journal Articles

Abstract 249: Inhibition of nestin using siRNA as a novel therapeutic option for pancreatic cancer.

Toshiyuki Ishiwata, Hisashi Yoshimura, Taeko Suzuki, Yuji Yanagisawa, Yoko Kawamoto, Kiyoko Kawahara, Zenya Naito, Murray Korc, Yoko Matsuda
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 249.
https://doi.org/10.1158/1538-7445.AM2013-249
Published: 15 April 2013
View article titled, Abstract 249: Inhibition of nestin using siRNA as a novel therapeutic option for pancreatic cancer.
Journal Articles

Abstract 2951: DUSP1 is a novel target for enhancing pancreatic cancer cell sensitivity to gemcitabine.

Fang Liu, Murray Korc
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2951.
https://doi.org/10.1158/1538-7445.AM2013-2951
Published: 15 April 2013
View article titled, Abstract 2951: DUSP1 is a novel target for enhancing pancreatic cancer cell sensitivity to gemcitabine.
Journal Articles

Abstract 4433: RB mediates TGF-β effects on growth inhibition and invasion in pancreatic cancer cells

Jesse Gore, Murray Korc
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4433.
https://doi.org/10.1158/1538-7445.AM2012-4433
Published: 15 April 2012
View article titled, Abstract 4433: RB mediates TGF-β effects on growth inhibition and invasion in pancreatic cancer cells
Journal Articles

Abstract 3055: PD-0332991, a selective cyclin-dependent-kinase 4/6 Inhibitor, upregulates multiple genes promoting invasion and metastasis in pancreatic ductal adenocarcinoma

Fang Liu, Murray Korc
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3055.
https://doi.org/10.1158/1538-7445.AM2012-3055
Published: 15 April 2012
View article titled, Abstract 3055: PD-0332991, a selective cyclin-dependent-kinase 4/6 Inhibitor, upregulates multiple genes promoting invasion and metastasis in pancreatic ductal adenocarcinoma
Journal Articles

Abstract 3076: p53 homologue p63 trans-activates epidermal growth factor (EGF) receptor and 14-3-3α and thus promotes tumorigenesis and chemoresistance in pancreatic cancer

Alexey V. Danilov, Amitabh Srivastava, Elena V. Feofanova, Leigh Ann Humphries, James Direnzo, Murray Korc
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3076.
https://doi.org/10.1158/1538-7445.AM2012-3076
Published: 15 April 2012
View article titled, Abstract 3076: <em>p53 homologue p63 trans-activates epidermal growth factor (EGF) receptor and 14-3-3α and thus promotes tumorigenesis and chemoresistance in pancreatic cancer</em>
Journal Articles

Abstract 177: MiR-10b promotes migration and invasion in pancreatic cancer cells

Haoxu Ouyang, Murray Korc
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 177.
https://doi.org/10.1158/1538-7445.AM2012-177
Published: 15 April 2012
View article titled, Abstract 177: MiR-10b promotes migration and invasion in pancreatic cancer cells
Journal Articles

Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer

Juan R. Cubillos-Ruiz, Jason R. Baird, Amelia J. Tesone, Melanie R. Rutkowski, Uciane K. Scarlett, Ana L. Camposeco-Jacobs, Jorge Anadon-Arnillas, Noah M. Harwood, Murray Korc, Steven N. Fiering, Lorenzo F. Sempere, Jose R. Conejo-Garcia
Journal: Cancer Research
Cancer Res (2012) 72 (7): 1683–1693.
https://doi.org/10.1158/0008-5472.CAN-11-3160
Published: 01 April 2012
View article titled, Reprogramming Tumor-Associated Dendritic Cells <em>In Vivo</em> Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer
Open the PDF for Reprogramming Tumor-Associated Dendritic Cells <em>In Vivo</em> Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 223: ΔNp63α, a p53 family member protein, promotes tumor progression in pancreatic cancer

Alexey Danilov, Divas Neupane, James DiRenzo, Murray Korc
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 223.
https://doi.org/10.1158/1538-7445.AM2011-223
Published: 15 April 2011
View article titled, Abstract 223: ΔNp63α, a p53 family member protein, promotes tumor progression in pancreatic cancer