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Mourad Tighiouart
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Journal Articles

Abstract PO1-19-07: A Phase I Study Accessing Immunotherapy Combination of Balstilimab and Ivermectin in Patients with Metastatic Triple Negative Breast Cancer

Yuan Yuan, Stephen Shiao, Mourad Tighiouart, Monica Mita, Jin-Sun Bitar, Philomena McAndrew, Park Dorothy, Maryliza El-Masry, Paul Frankel, Peter Lee
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-19-07.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-19-07
Published: 02 May 2024
View article titled, Abstract PO1-19-07: A Phase I Study Accessing Immunotherapy Combination of Balstilimab and Ivermectin in Patients with Metastatic Triple Negative Breast Cancer
Journal Articles

Abstract PO5-19-08: Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial

Heather McArthur, Jorge Henrique Santos Leal, Isaac Chan, Nisha Unni, Stephen Shiao, Joshua Gruber, Samira Syed, Namrata Peswani, Navid Sadeghi, Glenda Delgado, Dawn Klemow, Reva Basho, Meredith Carter, Mai Badran, Nasir Qureshi, Jessica Curtin, Joshua Weese, Stephanie Rice, Michelle Phillips, David Chan, Hugo Hool, Dorothy Park, Mary El-Masry, Philomena McAndrew, Swati Sikaria, Laura Spring, Aditya Bardia, Mourad Tighiouart, Farnaz Dadmanesh, Armando Giuliano, Katherine Sanchez, David Page
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-19-08.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-19-08
Published: 02 May 2024
View article titled, Abstract PO5-19-08: Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial
Journal Articles

Abstract OT3-25-01: Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial

Heather McArthur, Jorge Henrique Santos Leal, Christina DiLauro Abaya, Sangeetha Reddy, Meredith Carter, Reva Basho, Michelle Phillips, David Chan, Hugo Hool, Dorothy Park, Mary El-Masry, Philomena McAndrew, Swati Sikaria, Laura M. Spring, Aditya Bardia, Mourad Tighiouart, Farnaz Dadmanesh, Armando Giuliano, Stephen Shiao, David B. Page
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): OT3-25-01.
https://doi.org/10.1158/1538-7445.SABCS22-OT3-25-01
Published: 01 March 2023
View article titled, Abstract OT3-25-01: Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial
Journal Articles

Abstract PD5-04: Risk factors for long-term adjuvant chemotherapy toxicity using pre-treatment host factors and self-rated treatment bother (GP5) in a clinical trial population

N. Lynn Henry, Sungjin Kim, Ron D. Hays, Marcio A. Diniz, Michael Luu, Mourad Tighiouart, Reena S. Cecchini, Greg Yothers, Andre Rogatko, Patricia A. Ganz
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD5-04.
https://doi.org/10.1158/1538-7445.SABCS21-PD5-04
Published: 15 February 2022
View article titled, Abstract PD5-04: Risk factors for long-term adjuvant chemotherapy toxicity using pre-treatment host factors and self-rated treatment bother (GP5) in a clinical trial population
Journal Articles

Abstract OT2-04-04: Neoadjuvant HER2-targeted therapy +/- immunotherapy with pembrolizumab (neoHIP): An open label randomized phase 2 trial

Heather McArthur, Jorge Leal, David Page, Christina DiLauro Abaya, Reva Basho, Lindsey Ristow, Hannah Coleman, Stephen Shiao, Simon Knott, Monica Mita, Mourad Tighiouart, Alice Chung, Farnaz Dadmanesh, Philomena McAndrew, Scott Karlan, Sunil Verma, Armando Giuliano
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): OT2-04-04.
https://doi.org/10.1158/1538-7445.SABCS19-OT2-04-04
Published: 15 February 2020
View article titled, Abstract OT2-04-04: Neoadjuvant HER2-targeted therapy +/- immunotherapy with pembrolizumab (neoHIP): An open label randomized phase 2 trial
Journal Articles

Abstract B58: A phase I/II study of durvalumab and stereotactic radiotherapy in locally advanced pancreatic cancer

Richard Tuli, Nicholas Nissen, Simon Lo, Mourad Tighiouart, Veronica Placencio, Andrew Hendifar
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): B58.
https://doi.org/10.1158/1538-7445.PANCA19-B58
Published: 13 December 2019
View article titled, Abstract B58: A phase I/II study of durvalumab and stereotactic radiotherapy in locally advanced pancreatic cancer
Journal Articles

Abstract 5002: KRT13 promotes stemness and drives metastasis in breast cancer through direct interaction with plakoglobin-desmoplakin complexes regulating c-Myc signaling pathway

Lijuan Yin, Gina Chia-Yi Chu, Qinlong Li, Liyuan Yin, Michael Lewis, Mourad Tighiouart, Leland W. k. Chung, Haiyen E. Zhau
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5002.
https://doi.org/10.1158/1538-7445.AM2018-5002
Published: 01 July 2018
View article titled, Abstract 5002: KRT13 promotes stemness and drives metastasis in breast cancer through direct interaction with plakoglobin-desmoplakin complexes regulating c-Myc signaling pathway
Journal Articles

Abstract 1511: Stromal gene signature regulated by TGFβ signaling predicts poor clinical outcome in ovarian cancer .

Dong-Joo Cheon, Yunguang Tong, Myung-Shin Sim, Xiaojiang Cui, Dror Berel, Mourad Tighiouart, Wolf Ruprecht Wiedemeyer, Beth Karlan, Sandra Orsulic
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1511.
https://doi.org/10.1158/1538-7445.AM2013-1511
Published: 15 April 2013
View article titled, Abstract 1511: Stromal gene signature regulated by TGFβ signaling predicts poor clinical outcome in ovarian cancer .
Journal Articles

Abstract 112: An endogenous mTOR inhibitor, PRAS40, is upregulated in lung cancer and contributes to tumor cell invasion and chemoresistance

Zenggang Li, Yuhong Du, Gabriel Sica, Suresh S Ramalingam, Anthony A Gal, Lin Pan, Mourad Mourad Tighiouart, Fadlo R. Fadlo R. Khuri, Haian Fu
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 112.
https://doi.org/10.1158/1538-7445.AM2012-112
Published: 15 April 2012
View article titled, Abstract 112: An endogenous mTOR inhibitor, PRAS40, is upregulated in lung cancer and contributes to tumor cell invasion and chemoresistance
Journal Articles

Abstract 822: Withaferin A inhibits breast cancer invasion and metastasis at subcytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

Jose T. Thaiparambil, Laura Bender, Thota Ganesh, Erik Kline, Pritty Patel, Yuan Liu, Mourad Tighiouart, Paula M. Vertino, R Donald Harvey, Anapatricia Garcia, Adam Marcus
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 822.
https://doi.org/10.1158/1538-7445.AM2011-822
Published: 15 April 2011
View article titled, Abstract 822: Withaferin A inhibits breast cancer invasion and metastasis at subcytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
Journal Articles

Abstract LB-196: A folate receptor-targeted nanoparticle minimizes multidrug resistance in human cancer xenograft model

Xu Wang, Jun Li, Yuxiang Wang, Lydia Koenig, Ada Gjyrezi, Paraskevi Giannakakou, Edwin H. Shin, Mourad Tighiouart, Zhuo Chen, Shuming Nie, Dong M. Shin
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-196.
https://doi.org/10.1158/1538-7445.AM2011-LB-196
Published: 15 April 2011
View article titled, Abstract LB-196: A folate receptor-targeted nanoparticle minimizes multidrug resistance in human cancer xenograft model
Journal Articles

Abstract 1260: Analysis of death receptor 5 and caspase-8 expression in primary and metastatic head and neck squamous cell carcinoma and their prognostic impact

Heath A. Elrod, Songqing Fan, Susan Muller, Georgia Z. Chen, Lin Pan, Mourad Tighiouart, Dong M. Shin, Fadlo R. Khuri, Shi-Yong Sun
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1260.
https://doi.org/10.1158/1538-7445.AM10-1260
Published: 15 April 2010
View article titled, Abstract 1260: Analysis of death receptor 5 and caspase-8 expression in primary and metastatic head and neck squamous cell carcinoma and their prognostic impact
Journal Articles

Abstract 2333: Integrin β1 contributes to metastasis and prognosis of squamous cell carcinoma of the head and neck (HNSCC)

Dongsheng Wang, Yuxiang Wang, A.r.m Ruhul Amin, Ling Su, Susan Muller, Donghai Huang, Sreenivas Nannapaneni, Lydia Koenig, Zhengjia Chen, Lin Pan, Mourad Tighiouart, Dong Moon Shin, Zhuo (Georgia) Chen
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2333.
https://doi.org/10.1158/1538-7445.AM10-2333
Published: 15 April 2010
View article titled, Abstract 2333: Integrin β1 contributes to metastasis and prognosis of squamous cell carcinoma of the head and neck (HNSCC)
Journal Articles

Abstract #2449: Web-based head and neck cancer tissue database

Haibin Wang, Anna Kuehn, Erik Bouzyk, Susan Muller, Fadlo Khuri, Dong Shin, Mourad Tighiouart
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2449.
Published: 01 May 2009
View article titled, Abstract #2449: Web-based head and neck cancer tissue database
Journal Articles

Abstract #LB-163: A novel antiangiogenic feature of a dual targeting antibody (DMS3008) against EGFR and VEGF

Hongzheng Zhang, Sujin Yun, Thil Batuwangala, Michael Steward, Lin Pan, Mourad Tighiouart, Zhuo (Georgia) Chen, Dong M Shin
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-163.
Published: 01 May 2009
View article titled, Abstract #LB-163: A novel antiangiogenic feature of a dual targeting antibody (DMS3008) against EGFR and VEGF
Journal Articles

Abstract #3667: A novel folate receptor-targeted nanoparticle minimizes drug resistance in a human cancer model

Xu Wang, Yiqing Wang, Jun Li, Sreenivas Nannapaneni, Mourad Tighiouart, Zhuo (Georgia) Chen, Shuming Nie, Dong Shin
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3667.
Published: 01 May 2009
View article titled, Abstract #3667: A novel folate receptor-targeted nanoparticle minimizes drug resistance in a human cancer model
Journal Articles

BRCA1-Associated Protein-1 Is a Tumor Suppressor that Requires Deubiquitinating Activity and Nuclear Localization

Karen H. Ventii, Narra S. Devi, Kenneth L. Friedrich, Tatiana A. Chernova, Mourad Tighiouart, Erwin G. Van Meir, Keith D. Wilkinson
Journal: Cancer Research
Cancer Res (2008) 68 (17): 6953–6962.
https://doi.org/10.1158/0008-5472.CAN-08-0365
Published: 28 August 2008
View article titled, BRCA1-Associated Protein-1 Is a Tumor Suppressor that Requires Deubiquitinating Activity and Nuclear Localization
Open the PDF for BRCA1-Associated Protein-1 Is a Tumor Suppressor that Requires Deubiquitinating Activity and Nuclear Localization in another window
Journal Articles

IGF-I-dependent upregulation of ZEB1 expression drives EMT in human prostate cancer cells in vitro

Tisheeka Graham, Haiyen Zhau, Valerie Odero-Marah, Adeboye Osunkoya, Mourad Tighiouart, Tongrui Liu, Jonathan Simons, Ruth O'Regan
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3585.
Published: 01 May 2008
View article titled, IGF-I-dependent upregulation of ZEB1 expression drives EMT in human prostate cancer cells <em>in vitro</em>
Journal Articles

A dual antibody against EGFR and VEGF as a therapeutic agent for cancer treatment

Sujin Yun, Hongzheng Zhang, Sreenivas Nannapaneni, Michael Steward, Thil Batuwangala, Mourad Tighiouart, Selwyn Hurwitz, Zhuo (Georgia) Chen, Dong M Shin
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2401.
Published: 01 May 2008
View article titled, A dual antibody against EGFR and VEGF as a therapeutic agent for cancer treatment
Journal Articles

Efficacy of a novel folate receptor-targeted ternary nanoparticle in human cancer model

Xu Wang, Jun Li, Kwang Jae Cho, Sreenivas Nannapaneni, Mourad Tighiouart, Zhuo (Georgia) Chen, Shuming Nie, Dong Shin
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5730.
Published: 01 May 2008
View article titled, Efficacy of a novel folate receptor-targeted ternary nanoparticle in human cancer model