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Monica Tortoreto
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Journal Articles

Abstract 6726: Effectiveness of irinotecan plus trabectedin in a desmoplastic small round cell tumor patient-derived xenograft

Valentina Zuco, Sandro Pasquali, Monica Tortoreto, Stefano Percio, Valentina Doldi, Marta Barisella, Paola Collini, Gianpaolo Dagrada, Silvia Brich, Patrizia Gasparini, Marco Fiore, Michela Casanova, Anna Maria Frezza, Alessandro Gronchi, Silvia Stacchiotti, Andrea Ferrari, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6726.
https://doi.org/10.1158/1538-7445.AM2023-6726
Published: 04 April 2023
View article titled, Abstract 6726: Effectiveness of irinotecan plus trabectedin in a desmoplastic small round cell tumor patient-derived xenograft
Journal Articles

Abstract 2504: Antiarrhythmic drugs repositioning to counteract the activated phenotype of prostate cancer-associated fibroblasts

Valentina Doldi, Monica Tortoreto, Stefano Percio, Paolo Gandellini, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2504.
https://doi.org/10.1158/1538-7445.AM2023-2504
Published: 04 April 2023
View article titled, Abstract 2504: Antiarrhythmic drugs repositioning to counteract the activated phenotype of prostate cancer-associated fibroblasts
Journal Articles

Abstract 1106: Cisplatin-induced activation of SDF-1/CXCR4 axis sustains lung cancer metastasis by promoting co-recruitment of metastasis initiating cells and inflammatory monocytes

Giulia Bertolini, Valeria Cancila, Orazio Fortunato, Giuseppe Lo Russo, Monica Tortoreto, Giovanni Centonze, Massimo Milione, Claudio Tripodo, Stefania Scala, Gabriella Sozzi, Luca Roz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1106.
https://doi.org/10.1158/1538-7445.AM2020-1106
Published: 15 August 2020
View article titled, Abstract 1106: Cisplatin-induced activation of SDF-1/CXCR4 axis sustains lung cancer metastasis by promoting co-recruitment of metastasis initiating cells and inflammatory monocytes
Journal Articles

Abstract 5098: Cues from extracellular matrix produced by fibroblasts prime lung cancer cells for distant dissemination

Giuliana Pollaci, Francesca Giovinazzo, Ornella Rondinone, Antonina Bruccoleri, Federica Facchinetti, Monica Tortoreto, Ugo Pastorino, Giulia Bertolini, Gabriella Sozzi, Luca Roz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5098.
https://doi.org/10.1158/1538-7445.AM2020-5098
Published: 15 August 2020
View article titled, Abstract 5098: Cues from extracellular matrix produced by fibroblasts prime lung cancer cells for distant dissemination
Journal Articles

Abstract 1912: Inhibition of Exportin-1 function reverses the pro-tumorigenic potential of lung fibrotic microenvironments

Antonina Bruccoleri, Ornella Rondinone, Francesca Andriani, Federica Facchinetti, Monica Tortoreto, Gabriella Sozzi, Giulia Bertolini, Luca Roz
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1912.
https://doi.org/10.1158/1538-7445.AM2019-1912
Published: 01 July 2019
View article titled, Abstract 1912: Inhibition of Exportin-1 function reverses the pro-tumorigenic potential of lung fibrotic microenvironments
Journal Articles

Abstract 3289: Microenvironment modulation and enhancement of cytotoxic therapy by the heparanase inhibitor Roneparstat against human B-non Hodgkin lymphomas

Massimo Di Nicola, Franco Zunino, Anna Rossini, Giusi Ruggiero, Micheleandrea De Cesare, Denis Cominetti, Monica Tortoreto, Cinzia Lanzi, Giuliana Cassinelli, Roberta Zappasodi, Claudio Tripodo, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3289.
https://doi.org/10.1158/1538-7445.AM2016-3289
Published: 15 July 2016
View article titled, Abstract 3289: Microenvironment modulation and enhancement of cytotoxic therapy by the heparanase inhibitor Roneparstat against human B-non Hodgkin lymphomas
Journal Articles

Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM− Lung Cancer–Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis

Giulia Bertolini, Lucia D'Amico, Massimo Moro, Elena Landoni, Paola Perego, Rosalba Miceli, Laura Gatti, Francesca Andriani, Donald Wong, Roberto Caserini, Monica Tortoreto, Massimo Milione, Riccardo Ferracini, Luigi Mariani, Ugo Pastorino, Ilaria Roato, Gabriella Sozzi, Luca Roz
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (17): 3636–3649.
https://doi.org/10.1158/0008-5472.CAN-14-3781
Published: 31 August 2015
View article titled, Microenvironment-Modulated Metastatic CD133<sup>+</sup>/CXCR4<sup>+</sup>/EpCAM<sup>−</sup> Lung Cancer–Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis
Open the PDF for Microenvironment-Modulated Metastatic CD133<sup>+</sup>/CXCR4<sup>+</sup>/EpCAM<sup>−</sup> Lung Cancer–Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis in another window
Includes: Supplementary data
Journal Articles

Abstract 3898: Disseminated cells from primary lung cancers contain a distinct cancer initiating subpopulation with mesenchymal-like features

Giulia Bertolini, Massimo Moro, Monica Tortoreto, Roberto Caserini, Ugo Pastorino, Luca Roz, Gabriella Sozzi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3898.
https://doi.org/10.1158/1538-7445.AM2014-3898
Published: 01 October 2014
View article titled, Abstract 3898: Disseminated cells from primary lung cancers contain a distinct cancer initiating subpopulation with mesenchymal-like features
Journal Articles

Abstract 3440: CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce the incidence of tumor spreading and improve overall survival in preclinical models of prostate cancer.

Giovanni Luca Gravina, Monica Tortoreto, Andrea Mancini, Paola Muzi, Luca Ventura, Sandra D'ascenzo, Alessandro Addis, Yosef Landesman, Dilara McCauley, Vincenza Dolo, Michael Kauffman, Sharon Shacham, Nadia Zaffaroni, Claudio Festuccia
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3440.
https://doi.org/10.1158/1538-7445.AM2013-3440
Published: 15 April 2013
View article titled, Abstract 3440: CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce the incidence of tumor spreading and improve overall survival in preclinical models of prostate cancer.
Journal Articles

Abstract 4719: The HDAC inhibitor ITF2357 blocks c-Myc expression via microRNA modulation and cap-dependent translation inhibition in human Burkitt's lymphoma

Roberta Zappasodi, Alessandra Cavane', Marilena V. Iorio, Monica Tortoreto, Giusi Ruggiero, Michele Magni, Elda Tagliabue, Franco Zunino, Carlo M. Croce, Alessandro M. Gianni, Massimo Di Nicola
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4719.
https://doi.org/10.1158/1538-7445.AM2012-4719
Published: 15 April 2012
View article titled, Abstract 4719: The HDAC inhibitor ITF2357 blocks c-Myc expression via microRNA modulation and cap-dependent translation inhibition in human Burkitt's lymphoma
Journal Articles

Abstract 504: Epithelial-mesenchymal transition confers stem-like properties and migratory ability to lung tumor cells

Giulia Bertolini, Luca Roz, Monica Tortoreto, Mattia Boeri, Ugo Pastorino, Gabriella Sozzi
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 504.
https://doi.org/10.1158/1538-7445.AM2011-504
Published: 15 April 2011
View article titled, Abstract 504: Epithelial-mesenchymal transition confers stem-like properties and migratory ability to lung tumor cells
Journal Articles

Abstract 566: Interaction of acetyl-L-carnitine with platinum compounds: A possible role of protein acetylation in modulation of antitumor activity

Claudio Pisano, Loredana Vesci, Ferdinando Maria Milazzo, Mario Bernandino Guglielmi, Rosanna Foderà, Marcella Barbarino, Giovanna Petrangolini, Monica Tortoreto, Paolo Carminati, Claudio Cavazza, Franco Zunino
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 566.
https://doi.org/10.1158/1538-7445.AM10-566
Published: 15 April 2010
View article titled, Abstract 566: Interaction of acetyl-L-carnitine with platinum compounds: A possible role of protein acetylation in modulation of antitumor activity
Journal Articles

Abstract 1598: Vasculogenic properties of triple negative breast carcinoma cells: possible implication for new molecular target

Elda Tagliabue, Ilaria Plantamura, Erica Dugnani, Cristina Ghirelli, Monica Tortoreto, Isabella Barajon, Francesca Arnaboldi, Roberto Agresti, Maria Luisa Carcangiu, Andrea Balsari, Marilena V. Iorio
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1598.
https://doi.org/10.1158/1538-7445.AM10-1598
Published: 15 April 2010
View article titled, Abstract 1598: Vasculogenic properties of triple negative breast carcinoma cells: possible implication for new molecular target
Journal Articles

Abstract 2089: MiR-205 role in triple negative breast cancer

Marilena V. Iorio, Claudia Piovan, Gianpiero Di Leva, Patrizia Casalini, Monica Tortoreto, Ilaria Plantamura, Cristian Taccioli, Carlo M. Croce, Elda Tagliabue
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2089.
https://doi.org/10.1158/1538-7445.AM10-2089
Published: 15 April 2010
View article titled, Abstract 2089: MiR-205 role in triple negative breast cancer
Journal Articles

Abstract #257: Targeting heparanase as a therapy for multiple myeloma

Yang Yang, Joseph Ritchie, Li Nan, Annamaria Naggi, Giangiacomo Torri, Benito Casu, Claudio Pisano, Paolo Carminati, Sergio Penco, Monica Tortoreto, Franco Zunino, Israel Vlodavsky, Ralph Sanderson
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 257.
Published: 01 May 2009
View article titled, Abstract #257: Targeting heparanase as a therapy for multiple myeloma
Journal Articles

Abstract #1811: Antitumor activity of SST0001 a new heparin derivative targeting heparanase

Claudio Pisano, Benito Casu, Annamaria Naggi, Giangiacomo Torri, Sergio Penco, Walter Cabri, Monica Tortoreto, Franco Zunino, Loredana Vesci, Rosanna Foderà, Ferdinando Milazzo, Marcella Barbarino, Federica Bucci, Concetta Aulicino, Nicola Gargano, Elisa Beghetto, Adriano Angelucci, Mauro Bologna, Paolo Carminati
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1811.
Published: 01 May 2009
View article titled, Abstract #1811: Antitumor activity of SST0001 a new heparin derivative targeting heparanase
Journal Articles

Biological Properties of IDN5174, a New Synthetic Camptothecin with the Open Lactone Ring

Giovanni L. Beretta, Giovanna Petrangolini, Michelandrea De Cesare, Graziella Pratesi, Paola Perego, Stella Tinelli, Monica Tortoreto, Massimo Zucchetti, Roberta Frapolli, Ezia Bello, Carla Manzotti, Gabriele Fontana, Ezio Bombardelli, Arturo Battaglia, Cristian Samorì, Franco Zunino
Journal: Cancer Research
Cancer Res (2006) 66 (22): 10976–10982.
https://doi.org/10.1158/0008-5472.CAN-06-2158
Published: 15 November 2006
View article titled, Biological Properties of IDN5174, a New Synthetic Camptothecin with the Open Lactone Ring
Open the PDF for Biological Properties of IDN5174, a New Synthetic Camptothecin with the Open Lactone Ring in another window
Journal Articles

A novel inhibitor of vacuolar H+-ATPase, NIK-12192, potentiates the antitumor effect of topotecan in BCRP-expressing tumor systems.

Rosanna Supino, Giovanna Petrangolini, Anna C. Croce, Laura Dal Bo, Monica Tortoreto, Graziella Pratesi, Paola Misiano, Carlo Farina, Franco Zunino
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1273.
Published: 15 April 2006
View article titled, A novel inhibitor of vacuolar H<sup>+</sup>-ATPase, NIK-12192, potentiates the antitumor effect of topotecan in BCRP-expressing tumor systems.
Journal Articles

Therapeutic Synergism of Gemcitabine and CpG-Oligodeoxynucleotides in an Orthotopic Human Pancreatic Carcinoma Xenograft

Graziella Pratesi, Giovanna Petrangolini, Monica Tortoreto, Alessandro Addis, Sara Belluco, Anna Rossini, Silvia Selleri, Cristiano Rumio, Sylvie Menard, Andrea Balsari
Journal: Cancer Research
Cancer Res (2005) 65 (14): 6388–6393.
https://doi.org/10.1158/0008-5472.CAN-05-0602
Published: 15 July 2005
View article titled, Therapeutic Synergism of Gemcitabine and CpG-Oligodeoxynucleotides in an Orthotopic Human Pancreatic Carcinoma Xenograft
Open the PDF for Therapeutic Synergism of Gemcitabine and CpG-Oligodeoxynucleotides in an Orthotopic Human Pancreatic Carcinoma Xenograft in another window
Journal Articles

Gemcitabine plus CpG-oligodeoxinucleotides: Strong efficacy against a human pancreatic orthotopic tumor xenograft

Giovanna Petrangolini, Monica Tortoreto, Sylvie Menard, Lucia Sfondrini, Anna Rossini, Silvia Selleri, Alessandro Addis, Andrea Balsari, Graziella Pratesi
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 169.
Published: 01 May 2005
View article titled, Gemcitabine plus CpG-oligodeoxinucleotides: Strong efficacy against a human pancreatic orthotopic tumor xenograft